INCREASING RADIOLOGY VALUE IN PATIENT CARE: STANDARDIZED EVIDENCE-BASED SURVEILLANCE RECOMMENDATIONS FOR ABDOMINAL AORTIC ANEURYSMS

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1 INCREASING RADIOLOGY VALUE IN PATIENT CARE: STANDARDIZED EVIDENCE-BASED SURVEILLANCE RECOMMENDATIONS FOR ABDOMINAL AORTIC ANEURYSMS

2 AUTHORS Sameer Ahmed 1, Jason Mitsky 2, Upma Rawal 2, Pamela Johnson 1, Sheila Sheth 1, Jay Bronner 2, Syed Zaidi 2 1 Johns Hopkins Department of Radiology, Baltimore, MD 2 Radiology Partners Research Institute, El Segundo, CA Disclosures: No relevant disclosures

3 INTRODUCTION Abdominal aortic aneurysms (AAA) require surveillance to predict risk of rupture, with rupture-associated mortality rates as high as 90%. 1 Risk of rupture is proportional to the AAA maximum diameter. 2 Asymptomatic AAA with maximum diameter 5.5 cm and/or rapid expansion (>5 mm in 6 months or 10 mm per year) are indications for elective repair, which reduces mortality by up to 10-fold compared to emergent repair following rupture. 2,3 Hospital cost of emergent repair of a AAA is 30% greater than elective repair. 4 Inadequate radiological surveillance of AAA have increased rates of rupture and death, as well as decreased rates of elective repair. 5-7 Lack of appropriate follow-up imaging, not exclusive to AAA, is often related to breakdown of communication between the radiologist and the referring clinician, including failure to provide explicit recommendations within the radiology report We present a performance improvement initiative conducted by a large national multi-state private radiology practice, Radiology Partners, which through its Research Institute, developed best practice guidelines for AAA surveillance and successfully increased inclusion of these recommendations within the radiology report across the practice.

4 BEST PRACTICE GUIDELINES Table 1: Best Practice Recommendations for AAA Surveillance AAA Size (cm) Recommended Follow-up cm to 2.9 cm Every 5 years cm to 3.4 cm Every 3 years 3.5 cm to 3.9 cm Every 12 months 4.0 cm to 4.4 cm Every 12 months & Vascular consult 4.5 cm to 5.4 cm Every 6 months & Vascular consult > 5.5cm Referral to Vascular Surgeon 1. Based upon the Society for Vascular Surgery Guidelines: J Vasc Surg Oct;50(4 Suppl):S For aortas of maximum diameter cm meeting the criteria for AAA (> 1.5 x proximal normal segment) Table 1: Best Practice Recommendations for AAA Surveillance

5 BEST PRACTICE GUIDELINES Imaging surveillance is based on maximum external aortic diameter, measured from outer wall to outer wall, perpendicular to vascular flow. For aortas measuring cm, it is important to differentiate between ectasia and aneurysmal dilatation. In this size range, the recommendation is to follow only those aortas that meet the established criteria for aneurysm based on relative size the maximum diameter is 1.5 times the size of the proximal normal abdominal aortic segment. 11 One important divergence from published guidelines is the recommendation of early referral to a vascular specialist when an aortic diameter reaches 4.0 cm. This recommendation was based on a few important considerations: Therapeutic uncertainty for AAA in the range of 4.0 to 5.4 cm. 2 Young otherwise healthy patients may benefit from early repair before the aortic diameter reaches 5.5 cm. 1,2 Risk of aneurysm rupture is greater and occurs at smaller diameters in women than in men. 12 This suggests that indication for elective repair should be slightly more liberal for women due the smaller size of the normal female abdominal aorta. Larger aneurysms expand more rapidly than small ones, with baseline aneurysm size being the best predictor of growth rate. 13 Aneurysms with an initial size of cm may expand at twice the rate of those measuring cm and are at greater risk of rupture without proper surveillance. 13,14 Ultimately, the decision to intervene is individualized and best determined by an expert in vascular disease. Early referral to a vascular specialist will facilitate both appropriate imaging surveillance and individualized patient care.

6 INCLUSION OF BEST PRACTICE RECOMMENDATIONS WITHIN RADIOLOGY REPORT A structured reporting macro to be inserted within the radiology report was integrated into dictation software. A short training video was created to educate the radiologists on the AAA BPR and physician attestation to watching the video was tracked. Following a five-month training period, the inclusion of recommendations within the radiology report was monitored. Performance was evaluated and reported for each local practice comprising our national practice on a scorecard (Fig 1) and distributed practice-wide each month. As with any successful change management program, constant and consistent feedback is vital to maintain performance. We found that it is critical to provide feedback in the form of actionable monthly scorecards to the practice leadership that include not only performance of the practice as a whole, but also performance of individual radiologists as well. This depth of detail enables the practice s leadership to provide each radiologist with a list of their cases lacking adherence to the AAA BPR, which becomes an important learning tool for the radiologist to adapt their dictation. The feedback loop between practice leadership and individual radiologists is how the initiative becomes anchored in the radiologists daily workflow and the overall culture of the practice.

7 MONTHLY SCORECARD Feb 2017 Jan 2018 Figure 1: Scorecard of monthly composite scores by local practice for adherence to AAA BPR during post-aaa QI study duration

8 STUDY POPULATION The study population included 345 of the practice s inpatient and outpatient facilities in seven states. Baseline data prior to the quality improvement initiative was collected retrospectively and included all crosssectional imaging (CT, MRI, and ultrasound) between July 1, 2015 and December 31, A total of 64,090 consecutive cross-sectional radiology reports were reviewed from this time period 855 incidental AAA were identified (1.3% of all baseline studies). Post-QI intervention data was collected between June 1, 2016 and January 31, ,474 consecutive CT, MRI, and ultrasound reports were reviewed from this time period. 9,167 reports were positive for AAA (1.9% of all post-qi intervention studies).

9 STUDY POPULATION BASELINE POST-QI INTERVENTION Age Mean Range Gender Male 598 (69.9%) 6467 (70.5%) Female 257 (30.1%) 2697 (29.4%) Unknown 0 (0%) 8 (0.1%) AAA Size Mean ± SD (cm) 4.0 ± ± 1.1 Range (cm) Table 2: Patient characteristics

10 RESULTS % adherence to BPR 100% 90% 80% 70% 60% 50% 40% 30% 20% 10% 0% 77.2% 77.1% 68.5% 19.4% 0.0% 1.9% Surveillance Consult Referral Baseline Post QI Figure 2: Adherence to AAA BPR pre and post-aaa QI intervention

11 PREDICTIVE MODEL Based on published rates of aneurysm rupture 15,16,17, a predictive model was created to estimate the potential number of ruptures averted and lives saved. We assumed aneurysm rupture rates at the midpoints of published ranges: 0.5% for <4 cm, 2.8% for cm, 9% for cm, 15% for cm, 30% for cm, and 40% for 8.0 cm. Based on these estimates, a total of 276 ruptures can be potentially averted during our study period with appropriate adherence to surveillance recommendations and timely intervention. Assuming a mortality rate of 90% following spontaneous rupture, a total of 248 lives may be saved over the course of 31 months (combination of pre- and post-intervention periods). Results from our predictive model are presented in Table 3.

12 PREDICTIVE MODEL Baseline Post QI Intervention Combined AAA size (cm) Rupture Rate 1 Cases Lives Saved 2 Cases Lives Saved 2 Cases Lives Saved 2 < % % % % % % Totals Average Annual Rupture Rate J Vasc Surg. May 2003;37(5): Lives Saved = Rupture Rate x Number of Cases x 90% (overall mortality rate for ruptured AAA) Table 3: Predictive model of potential lives saved over duration of study (31 months) through adherence to AAA BPR

13 CONCLUSION To our knowledge, this is the first study to report the frequency of radiology reports with AAA imaging follow-up recommendations. Our baseline data demonstrates a dramatic need for improvement on the part of the radiologist to include such recommendations. It is imperative to first establish best practice guidelines for AAA surveillance with consensus between radiology and vascular specialists in the institution. Following the implementation of the QI initiative and a training period, compliance tracking and monthly scorecard reporting are powerful drivers for performance improvement. To our knowledge, this is also the first reported quality improvement initiative to address the need for inclusion of AAA surveillance recommendations within the radiology report and document performance improvement. Radiologists are now charged to implement best practice recommendations in the imaging reports and develop automated mechanisms to facilitate communication to both provider and patient. National implementation of this performance improvement initiative will result in measurable decreases in AAA rupture, thereby decreasing mortality rates and costs.

14 REFERENCES 1. Hirsch AT, Haskal ZJ, Hertzer NR, et al. ACC/AHA 2005 practice guidelines for the management of patients with peripheral arterial disease (lower extremity, renal, mesenteric, and abdominal aortic): A collaborative report from the American Association for Vascular Surgery/Society for Vascular Surgery, Society for Cardiovascular Angiography and Interventions, Society for Vascular Medicine and Biology, Society of Interventional Radiology, and the ACC/AHA task force on practice guidelines (writing committee to develop guidelines for the management of patients with peripheral arterial disease): Endorsed by the American Association of Cardiovascular and Pulmonary Rehabilitation; National Heart, Lung, and Blood Institute; Society for Vascular Nursing; TransAtlantic Inter-society Consensus; and Vascular Disease Foundation. Circulation. 2006;113(11): Chaikof EL, Brewster DC, Dalman RL, et al. The care of patients with an abdominal aortic aneurysm: The society for vascular surgery practice guidelines. J Vasc Surg. 2009;50(4 Suppl):2. 3. Dueck AD, Kucey DS, Johnston KW, Alter D, Laupacis A. Long-term survival and temporal trends in patient and surgeon factors after elective and ruptured abdominal aortic aneurysm surgery. J Vasc Surg. 2004;39(6): Haider AH, Obirieze A, Velopulos CG, et al. Incremental cost of emergency versus elective surgery. Ann Surg. 2015;262(2): Mell MW, Baker LC, Dalman RL, Hlatky MA. Gaps in preoperative surveillance and rupture of abdominal aortic aneurysms among medicare beneficiaries. J Vasc Surg. 2014;59(3): van Walraven C, Wong J, Morant K, Jennings A, Jetty P, Forster AJ. Incidence, follow-up, and outcomes of incidental abdominal aortic aneurysms. J Vasc Surg. 2010;52(2):2. 7. van Walraven C, Wong J, Morant K, et al. The influence of incidental abdominal aortic aneurysm monitoring on patient outcomes. J Vasc Surg. 2011;54(5):1297.e2. 8. Zafar HM, Bugos EK, Langlotz CP, Frasso R. "Chasing a ghost": Factors that influence primary care physicians to follow up on incidental imaging findings. Radiology. 2016;281(2): Berlin L. Pitfalls of the vague radiology report. AJR Am J Roentgenol. 2000;174(6): Sloan CE, Chadalavada SC, Cook TS, Langlotz CP, Schnall MD, Zafar HM. Assessment of follow-up completeness and notification preferences for imaging findings of possible cancer: What happens after radiologists submit their reports? Acad Radiol. 2014;21(12): Khosa F, Krinsky G, Macari M, Yucel EK, Berland LL. Managing incidental findings on abdominal and pelvic CT and MRI, part 2: White paper of the ACR incidental findings committee II on vascular findings. J Am Coll Radiol. 2013;10(10): Thompson MM. Controlling the expansion of abdominal aortic aneurysms. Br J Surg. 2003;90(8): Isselbacher EM. Thoracic and abdominal aortic aneurysms. Circulation. 2005;111(6): Lindholt JS, Vammen S, Juul S, Fasting H, Henneberg EW. Optimal interval screening and surveillance of abdominal aortic aneurysms. Eur J Vasc Endovasc Surg. 2000;20(4): Brewster DC, Cronenwett JL, Hallett JW, et al. Guidelines for the treatment of abdominal aortic aneurysms. report of a subcommittee of the joint council of the american association for vascular surgery and society for vascular surgery. J Vasc Surg. 2003;37(5): Brown LC, Powell JT. Risk factors for aneurysm rupture in patients kept under ultrasound surveillance. UK small aneurysm trial participants. Ann Surg. 1999;230(3): Scott RA, Tisi PV, Ashton HA, Allen DR. Abdominal aortic aneurysm rupture rates: A 7-year follow-up of the entire abdominal aortic aneurysm population detected by screening. J Vasc Surg. 1998;28(1):

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