QUALITY Quality Excipients for Pharma and Biopharma Applications

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1 QUALITY Quality Excipients for Pharma and Biopharma Applications

Excipients for Pharmaceutical Production This is a selection of top products, if you are interested in a specific product that is not listed, please contact us.

2 Excipients for Pharmaceutical Production This is a selection of top products, if you are interested in a specific product that is not listed, please contact us. Buffering agents Control of ph is critical to avoid degradation of drug during processing, storage and reconstitution, there by necessitating addition of buffering agents in the Injectable formulation. Wide range of buffering agents are available in order to achieve predetermined ph range for the maximum stability and solubility of the API. CI132 SO138 SO187 S1986 AM180 Citric Acid Monohydrate, Granular, USP Dibasic Sodium Phosphate, Dried, USP Monobasic Sodium Phosphate, Anhydrous, USP Sodium Citrate, Anhydrous, USP Strong Ammonia Solution, NF About us At PLANET SCIENCE, we understand our customers need and provide them, with the best suitable solution. Our customers demand the best, That s where PLANET SCIENCE is invaluable. When you need the best - we deliver. We not only provide the highest quality products but also technical support and regulatory documentation support for all our ingredients. Our in-house expertise on the end use application of our products is complemented by the technical excellence of the scientists at Spectrum Chemicals USA, Panreac Applichem Germany and Koster Keunen USA. Because of our long cherished relationship with these wizards, our customers automatically get access to the decades of scientific and technical experience from all our principals Spectrum, Panreac & Koster. PLANET SCIENCE & its principals do not cut corners, we stand behind our products to assure you, our valued customer, the highest quality excipients. We bring all our USP, EP, BP, JP, FCC grade excipients from current Good Manufacturing Practices (cgmp) per 21CFR, part 210 and 211 of the code of federal regulations, our FDA registered and inspected manufacturing, packaging and storing facilities, will support and make sure you need not receive anything less than the highest grade of excipients at the best price. Their state-of-the art manufacturing facilities are always dedicated to providing products that exceed industry standards. In order to provide timely service to our customers, we maintain inventory for our fast moving products at our central warehouse situated at Mumbai. Call PLANET SCIENCE today, and put our experience, expertise, and resources to work for you. Solvents & Co-Solvents Co- Solvents & Solvents are used in the formulation for increasing drug solubility and primary drying rate in case of lyophilized products and in certain case enhance the sterility assurance of sample solution. BE159 Benzyl Benzoate, USP Benzyl Benzoate (USP, BP, Ph. Eur.) Pharma Grade Benzyl Alcohol (USP-NF, BP, Ph. Eur.) Pharma Grade DU0462 Dibutyl Phthalate, NF (Complies BP) Dichloromethane stabilized with ~ 20 ppm of amylene (USP-NF, BP, Ph. Eur.) Pharma Grade Dimethyl Sulfoxide (USP, BP, Ph. Eur.) Pharma Grade N,N-Dimethylacetamide (BP, Ph. Eur.), Pharma Grade ET108 Ethanol 95% (190 Proof), USP Ethanol 96% v/v (Ph.Eur, BP, USP) GMP- IPEC Grade Ethanol absolute (Ph. Eur, BP, USP-NF, JP) GMP-IPEC Grade Hexylene Glycol (USP-NF), Pharma Grade Oleic Acid (Ph. Eur.) Pharma Grade O1181C Oleic Acid, NF Propanol (USP, BP, Ph. Eur.), Pharma Grade BR0294 Tert-Butyl Alcohol, ACS (Complies reag. USP ) Triethanolamine (BP, Ph. Eur., USP-NF), Pharma Grade Complexing agents Complexing agents are used to increase aqueous solubility of poorly soluble drugs and to increase their bioavailability and stability. H1235C S2400C (2-Hydroxypropyl)-beta-cyclodextrin (HPBCD), EP Sulfobutylether beta cyclodextrin sodium (SBEBCD), USP

3 Antimicrobial preservatives Antimicrobial preservatives are used to kill or prevent growth of bacteria, yeast and mould in the dosage forms, antimicrobial agents are added to multi-dose formulations to prevent microbial growth during its shelf life and also added in the diluent for reconstitution of multidose container. BE158 Benzyl Alcohol, NF Benzyl Alcohol (USP-NF, BP, Ph. Eur.) Pharma Grade Chlorocresol, (USP-NF, BP, Ph. Eur.) Pharma Grade C2773 Metacresol, USP,EP ( Inj Grade ) Methylparaben (USP-NF, BP, Ph. Eur., JP) Pharma Grade ME163 Methylparaben, NF P1077 Phenoxyethanol, ( Complies NF) P1058 Phenylethyl Alcohol, USP PO301 Potassium Sorbate, Granular, NF PO300 Potassium Sorbate, Powder, NF PR133 Propylparaben, NF, BP, EP SO215 Sorbic Acid, Powder, NF Sorbic Acid (USP-NF, BP, Ph. Eur.) Pharma Grade S1172 Sodium Bisulfite, Granular, FCC ( Complies USP) Viscosity modifier/viscosity building agents Viscosity modifiers are used in pharmaceutical formulations to provide desired thickness to achieve suspendibility. We have wide range of CMC sodium with varied viscosity for optimum sedimentation rate. CA193 Carboxymethylcellulose Sodium, Low Viscosity, Viscosity of 2 Percent Aqueous 25 DEG C: cp, USP ph modifiers / ph adjusting agents A ph modifier is an acidifying or alkalizing agent used extensively in Injectable formulations to achieve a desirable ph for drug solubility, activity, absorption, stability and most importantly patient comfort. AL226 Dried Aluminum Hydroxide Gel, Powder, USP H1235C Hydroxypropyl beta-cyclodextrin (HPBCD) EP (Inj. Grade) L1010 Lactic Acid, Racemic, USP S2690C Sulfobutylether beta cyclodextrin sodium, USP (Inj. Grade) TA105 Tartaric Acid, Granular, NF L(+)-Tartaric Acid (USP-NF, BP, Ph. Eur.) pharma grade Tonicity adjusting agents Parenteral formulations should be isotonic with human plasma so as to avoid damage to the tissues. Utmost care should be taken, when either the injection volume or the infusion rate is higher, in case of intravenous injection. DE140 DE145 Dextrose, Anhydrous, Granular, USP, EP, BP, JP Dextrose, Monohydrate, Powder, USP Thickeners/Thicking agents A thickening agent or thickener is a substance which can increase the viscosity of a liquid without substantially changing its other properties. GU117 GU115 C1888 GM331C WAX#262P Emulsifiers & Stabilizers Emulsifiers are substances which make it possible to form or maintain a homogenous mixture of two or more immiscible phases such as oil and water in a foodstuff. Stabilizers are substances which make it possible to maintain the physico-chemical state of a product. Stabilizers include substances which enable the maintenance of a homogenous dispersion of two or more immiscible substances. GM331C IS160 M1122 M1122C PO125 Glyceryl Monostearate, USP Isopropyl Palmitate, NF Meglumine, USP Meglumine, USP,BP, EP, JP Polyethylene Glycol 3350, NF P1154 Polyethylene Glycol 400 Monostearate ( DMF Grade ) S1485 Sodium Tartrate, Dihydrate, Crystal, Reagent, ACS Sodium Tartrate, Dihydrate Reag. (Ph.Eur) Analysis Sorbitan Monolaurate (USP-NF, BP, Ph. Eur.) Pharma Grade SPA63 Acacia, Milled Powder, NF Acacia, Spray-Dried Powder, NF Cetostearyl Alcohol, NF Glyceryl Monostearate, USP White Beeswax, NF Sorbitan Monostearate, NF Sorbitan Monostearate (USP-NF, BP, Ph. Eur.) Pharma Grade Antioxidants & Reducing agents An antioxidant is a molecule that inhibits the oxidation of other molecules or itself gets oxidized in place of active. AS105 Ascorbic Acid, Crystalline Powder, USP AS102 Ascorbic Acid, Granular, USP L(+)-Ascorbic Acid (USP, BP, Ph. Eur.) Pharma Grade Butylated Hydroxytoluene (BP, Ph. Eur.) Pharma Grade B1196 Butylated Hydroxytoluene, Granular, NF Butylated Hydroxyanisole Powder (USP-NF, BP, Ph. Eur.) Pharma Grade B1194 Butylated Hydroxyanisole, Flakes, NF M1177 Monothioglycerol ( Complies USP ) P1453 Propyl Gallate, NF S1349 Sodium Ascorbate, Powder, USP S1172 Sodium Bisulfite, Granular, FCC ( Complies USP)

4 Oils for Pharma & Personal Care Molecules that are non-ionisable, lipophilic, and nonpolar are challenging to formulate due to their low water solubility and no effect of ph on solubility, thus non polar oils are mostly used to solve the purpose Castor Oil (BP, Ph. Eur.) Pharma Grade CA208 MI501 MI500 PE090 SO255 Castor Oil, USP Light Mineral Oil, NF Mineral Oil, USP Peanut Oil, NF Soybean Oil, USP Taste Modifiers/ Sweeteners Taste-modifying compounds or taste modifiers are chemical substances that alter one or more of the basic taste. Many studies have discovered numerous types of taste-modifying proteins found in nature that are categorized as having sweet, antisweet, and sweetness-inducing abilities. DE140 Dextrose, Anhydrous, Granular, USP, EP, BP, JP SO200 Saccharin Sodium, Dihydrate, Powder, USP SA105 Saccharin, Powder, NF L(+)-Tartaric Acid (USP-NF, BP, Ph. Eur.) Pharma Grade TA105 Tartaric Acid, Granular, NF Our Core Strengths Strict adherence to cgmp regulations Adopted IPEC-PQG GMP guide for pharmaceutical excipients Multinational principals from US & Europe, that are renowned and respected globally Comprehensive support for regulatory documentation Excipients for Injectable / Ophthalmic dosage forms Excipients for Dermatological/Semi-solid dosage forms Excipients for Liquid dosage forms Highly evolved business processes that meet the global quality standards Single product compliance to different pharmacopoeias (Multicompendial offerings) Sourcing from world renowned manufacturers across the globe Lubricants & Glidants Lubricants prevent ingredients from clumping together and from sticking to the tablet punches or capsule filling machine. Lubricants also ensure that tablet formation and ejection can occur with low friction between the solid and die wall. Glidants are used to promote powder flow by reducing interparticle friction and cohesion. These are used in combination with lubricants as they have no ability to reduce die wall friction. D1097 Diethyl Phthalate, NF Hexylene Glycol, USP Pharma Grade Custom-made products to meet specifications, precisely Prompt sample support for initiation of critical projects Highly skilled & technically sound manpower to resolve customer queries Wide variety of pack sizes that comply with both, R & D levels and commercial batches Zero compromise on customer-centric solutions Nationwide reach to support established and growing business entities Ample warehouse space to stock all fast moving products Ingredients/Constituents Benzoyl Peroxide humidified with ~ 25% of H 2 O (USP, BP, Ph. Eur.) Pharma Grade BE156 Hydrous Benzoyl Peroxide, USP C1473 Cysteine Hydrochloride, Monohydrate, USP G1044 Guar Gum, USP HY113 Hydroquinone, USP O1236 Octisalate, USP SA130 Salicylic Acid, Powder, USP Salicylic Acid (USP, BP, Ph. Eur.) Pharma Grade Sodium chloride ASTM B ( For Aeronautical Applications ) Sodium Succinate 6-hydrate for Pharma Analysis Logistic support that ensures JIT (Just in time) delivery High-priority for meeting safety standards, right from manufacturing to delivery Provision of audit (on request) at manufacturing plants

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5 Registered Office: G,A-48, Lake City Mall, Kapurbavdi Circle, Thane (W) , Mumbai, Maharashtra, INDIA T: (100 Lines) For Technical Queries : E: info@planetscience.in W: A Division of Planet Science Sales Office: 706,Lodha Supremus,Road No 22, Wagle Industrial Estate, Thane(W) Mumbai, Maharashtra, INDIA T: (7 lines) E: info@qualityexcipients.com W:

Manufacturer of High Purity Chemicals PRODUCT LIST

Manufacturer of High Purity Chemicals PRODUCT LIST Ammonium NH4 Ammonium Jost Chemical Co. manufactures a range of high purity ammonium phosphates, sulfates and citrates. Ammonium phosphates can be used