PRODUCT TECHNICAL DOSSIER. L-CYSTEINE HCl MONOHYDRATE

Transcription

1 PRODUCT TECHNICAL DOSSIER L-CYSTEINE HCl MONOHYDRATE Product Code: P0352 Raw Material Full Name: L-Cysteine Hydrochloride Monohydrate Raw Material Full Botanical/Chemical/Latin/Trade Name/Synonyms: L-Cysteine Hydrochloride Monohydrate This material is Food Grade Limit/Range/Specification: 98.5% % CAS Number: EC/EINECS Number: Molecular Formula for the raw material: C 3 H 7 NO 2 S. HCL. H 2 O Average Molecular weight: Solubility in Water: >98% ph: Loss on Drying: %

2 Residue on Ignition: Max 0.10% Identification: Infrared Absorption Specific Rotation: 5.5 o 7.0 o Chloride Content: 19.89% % Ammonium (NH4+): Max 0.02% Sulphate (SO42-): Max 0.02% Country of Origin: China Country of Origin of the Manufacture: China Base Source/Start Material: Duck Feathers Material is: 100% Compound Ingredients: None Shelf Life from Date of Manufacture: 2 Years Storage Conditions: This material is to be stored in a tightly sealed bag/container and to be kept in a cool place away from moisture and direct sunlight.

3 Appearance: Free Flowing Crystals/Crystalline Powder Colour: White/Off White Flavour/Taste: Acidic Taste Texture: Powder Odour: Characteristic Metals Heavy Metals Max 10ppm Arsenic (As): Max 1ppm Iron (Fe): Max 10ppm Lead (Pb): Max 3ppm Mercury (Hg): Max 0.1ppm Cadmium (Cd): Max 1ppm Pharmacopeia Standard Used: AJI92 There are no nuts in this recipe and are no nuts on site, however we cannot guarantee that the raw materials entering the site are nut free.

4 INTOLERANCE DATA If No please give details Free from All Animal Products (Beef, Pork, Poultry or other) NO Duck Feathers Free from Bovine Products or Derivatives by using hormones to increase milk yield in cows Free from Bone Meal Free from Peanuts and Peanut Derivatives (including possible cross contamination) Free from other Nut and Nut Derivatives Free from Nut Derived Oil Free from Sesame Seeds and Sesame Seed Derivatives Free from Poppy Seeds and Poppy Seed Derivatives Free from Sunflower Seeds and Sunflower Seeds Derivatives Free from other Seeds and Seed Derivatives Free from Milk and Milk Derivatives (including lactose) Free from Egg and Egg Derivatives Free from Cereals containing Gluten (wheat / rye / oats / barley/ spelt/ kamut or their hybridised strains) and Derivatives Free from Soya and Soya Derivatives Free from Maize and Maize Derivatives Free from Corn and Corn Derivatives Free from Lupin and Lupin Derivatives Free from Yeast and Yeast Derivatives Free from Cotton Seeds (Flour) and Cotton Seed Derivatives Free from Rice and Rice Derivatives Free from Mustard and Mustard Derivatives Free from Celery or Celery Derivatives Free from Celeriac or Celeriac Derivatives Free from Fruit and Fruit Derivatives Free from Vegetable and Vegetable Derivatives Free from Carrot and Carrot Derivatives Free from Legumes / Pulses Free from Fish and Fish Derivatives Free from Crustaceans / Molluscs and their Derivatives Free from Additives Free from Added Salt Free from Added Sugar Free from Antioxidants Free from Artificial Glutamates Free from Aspartame Free from Azo and Coal Tar Dyes Free from Benzoates (E210 / E219) Free from BHA / BHT (E320 / E321) Free from Caffeine Free from Cinnamon Free from Cocoa Free from Colours (Artificial / Nature Identical / Natural / Smoked) Free from Dextrose Free from Dioxins Free from Ethanol

5 INTOLERANCE DATA If No please give details Free from Ethylene Oxide Free from Flavourings (Artificial / Nature Identical / Natural / Smoked) Free from Garlic Free from Gelatine Free from Glutamates (E620 to E625) Free from Histamine Free from Hickory Free from Honey Free from Lactose Free from Latex Free from MSG (Added and Naturally Occurring E621) Free from Nucleotides (E627, E630, E631, E635) Free from Polyols Free from Preservatives Free from Starch Products (Including Maltodextrin) Free from Sorbic Acid (E200, E203) Free from Sulphur Dioxide and Sulphites at levels above 10mg/kg or 10mg/litre expressed as SO 2 Free from Sulphites (E220, E228) Free from Sweeteners Free from Vannillin Suitable for Diabetics Suitable for Coeliacs Suitable for Ovo-Lacto Vegetarians NO Duck Feathers Suitable for Vegans NO Duck Feathers Kosher Certified NO Not Certified Halal Certified NO Not Certified

6 CONFIRMATION OF BSE/TSE STATUS This is to certify that this product complies with all relevant current UK and EU Legislative requirements in regard to Transmissible Spongiform Encephalopathies (TSE) and Bovine Spongiform Encephalopathy (BSE) for human food, and so is free of TSE/BSE. This is also to certify that, during the course of their manufacture, the above-mentioned product did not come into contact with any materials, which could be derived from TSE/BSE risk materials. CONFIRMATION OF GM STATUS This is to certify that this product is not manufactured from GM raw materials and is therefore not subject to labelling under regulations 1829/2003/EC and 1830/2003/EC. CONFIRMATION OF NON IRRADIATION STATUS This is to certify that this product, whole or in part, has not been subjected to Ionising Radiation as per European Directives 1999/2/EC and 1000/3/EC. CONFIRMATION OF NANDROLONE STATUS This is to certify that this product, whole or in part, has not come into contact with Nandrolone or any of its precursors in any way. CONFIRMATION OF IOC PRODUCT STATUS This is to certify that this product, whole or in part, has not come into contact with any product/s, which is banned by the IOC (International Olympics Committee). CONFIRMATION OF ANIMAL TESTING STATUS This is to certify that all the products sold by Cambridge Commodities have not been tested on animals in any part of its manufacture in accordance with regulation 86/609/EEC. CONFIRMATION OF PESTICIDES STATUS This is to certify that the above-mentioned product complies with the regulation (EC) No.396/2005 of 23 rd February 2005 and commission Regulation (EU) No. 559/2011 of 7 th June 2011 amending annexes II and III of the above Regulation.

7 PRODUCT FLOW CHART Duck Feathers Hydrolysis Decolouring Filtrating Crystallization Centrifugation Drying Dissolving Electrolysis Decolouring Filtrating

8 PRODUCT FLOW Continued Ultra filtrating Concentration Crystallizing Centrifugation Drying Finished product

9 SAFETY DATA SHEET (REACH regulation (EC) No 1907/2006 NO 453/2010) SECTION 1: IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND THE COMPANY UNDERTAKING 1.1 Product identifier Product Name: Product Code: L-CYSTEINE HCL MONOHYDRATE P Details of the Supplier of the safety data sheet: Cambridge Commodities Limited 59 Lancaster Way, Ely, Cambridgeshire, CB6 1NW. Tel: SECTION 2 HAZARDS IDENTIFICATION 2.1 Classification of the substance or mixture In compliance with EC regulation No. 1272/2008 and its amendments Skin irritation, Category 2. Eye irritation, Category 2. Specific target organ toxicity (single exposure), Category 3. This substance does not represent a physical hazard. This substance does not represent an environmental hazard under standard conditions of use. In compliance with directives 67/548/EEC, 1999/45/EC and their amendments. Possibility of irritation to the eyes, by inhalation and skin. 2.2 Label elements In compliance with EC regulation No 1272/2008 and its amendments. Hazard pictograms:

10 Section 2 Continued GHSO7 Signal Word: WARNING Product identifiers: EC CYSTEINE HYDROCHLORIDE MONOHYDRATE Hazard statements: H315 H319 H335 Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation. Precautionary statements Prevention: P271 P280 Use only outdoors or in well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection Precautionary statements Response: P302 + P352 P304 + P340 P305 + P351 + P338 IF ON SKIN: Wash with plenty of soap and water. IF INHALED; Remove victim to fresh air and keep at rest in a position comfortable for breathing. IF IN E: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing. In compliance with directives 67/548/EEC, 1999/45/EC and their amendments. Hazard symbols: Irritant Risk phrase: R36/37/38 Irritating to eyes, respiratory system and skin. Safety phrase: S24/25 Avoid contact with skin and eyes 2.3. Other hazards

11 SECTION 3: COMPOSITION/INFORMATION ON INGREDIENTS. 3.1.Substances No substances fulfil the criteria set forth in annexe II section A of the REACH regulation (EC) n o 1907/ Mixtures Composition Identification Name Classification % CAS: CYSTEINE HYDROCHLORIDE GHS07, Wng 100% EC: MONOHYDRATE Xi H: R: 36/37/38 SECTION 4: FIRST AID MEASURES As a general rule, in case of doubt or if symptoms persist, always call a doctor. NEVER induce swallowing by an unconscious person. 4.1.Description of first aid measures. In the event of exposure by inhalation: In the event of massive inhalation of dust, remove the person to fresh air. Keep warm and at rest. If the person is unconscious, place in recovery position. Notify a doctor in all events, so as to ascertain whether observation and supportive hospital care will be necessary. If breathing is irregular or has stopped, effect mouth to mouth resuscitation and call a doctor. In the event of splashes or contact with eyes: Wash thoroughly with soft, clean water for 15 minutes holding the eyelids open. If there is any redness, pain or visual impairment, consult an ophthalmologist. In the event of splashes or contact with the skin: Remove contaminated clothing and wash the skin thoroughly with soap and water or a recognised cleaner. Watch out for any remaining product between skin and clothing, watches, shoes, etc. If the contaminated area is widespread and/or there is damage to the skin, a doctor must be consulted. In the event of swallowing: Do not give the patient anything orally. If the quantity is small (no more than a mouthful), rinse the mouth with water and consult a doctor. Seek medical attention immediately, showing the label if possible.

12 Section 4 Continued 4.2. Most important symptoms and effects, both acute and delayed: 4.3. Indication of any immediate medical attention and special treatment needed: No data available SECTION 5: FIREFIGHTING MEASURES Non-flammable Extinguishing media 5.2. Special hazards arising from the substance or mixture: A fire will often produce a thick black smoke. Exposure to decomposition products may be hazardous to health. Do not breathe in smoke. In the event of a fire the following may be formed: -Carbon monoxide (CO) -Carbon dioxide (CO2) 5.3. Advice for fire fighters No data available SECTION 6: ACCIDENTAL RELEASE MEASURES 6.1. Personal precautions, protective equipment and emergency procedures Consult the safety measures listed under headings 7 and 8 For non-fire fighters Avoid any contact with the skin and eyes. Avoid inhaling dust. If a large quantity has been spilt, evacuate all personnel and only allow intervention by trained operators. For fire fighters Fire fighters will be equipped with suitable personal protective equipment (See section 8) Environmental precautions Prevent any material from entering drains or waterways Methods and materials for containment and clearing up Retrieve the material by mechanical means (sweeping/vacuuming). Do not generate dust 6.4. Refere3nce to other sections

13 SECTION 7: HANDLING AND STORAGE Requirements relating to storage premises apply to all facilities where the substance is handled Precautions for safe handling Always wash hands after handling. Remove and wash contaminated clothing before re-using. Fire prevention Handle in well ventilated areas. Prevent access by unauthorised personnel. Recommended equipment and procedures For personal protection, see section 8. Observe precautions stated on label and also industry safety regulations. Provide breathing apparatus for certain short tasks of an exceptional nature and for emergency interventions. In all cases, recover emissions at source. Avoid skin and eye contact with this substance. Prohibited equipment and procedures No smoking, eating or drinking in areas where the substance is used Conditions for safe storage, including any incompatibilities Storage Keep the container tightly closed in a dry, well ventilated place Packaging Always keep in packaging made of an identical material to the original Specific end use(s)

14 SECTION 8: EXPOSURE CONTROLS/PERSONAL PROTECTION 8.1. Control parameters 8.2. Exposure controls Personal protection measures, such as personal protective equipment Use personal protective equipment that is clean and has been properly maintained. Store personal protective equipment in a clean place, away from the work area. Never eat drink or smoke during use. Remove and wash contaminated clothing before re-using. Ensure that there is adequate ventilation, especially in confined areas. Eye/face protection Avoid contact with eyes. Before handling powders or dust emission, wear mask goggles in accordance with standard EN166. Prescription glasses are not considered as protection. Provide eye wash stations in facilities where the product is handled constantly. Hand protection Protective creams may be used for exposed skin, but they should not be applied after contact with product. Wear suitable protective gloves in the event of prolonged or repeated skin contact. Use suitable protective gloves that are resistant to chemical agents in accordance with standard EN374. Gloves must be selected according to the application and duration of use at the workstation Protective gloves need to be selected according to their suitability for the workstation in question: other chemical products that may be handled, necessary physical protections(cutting, pricking, heat protection), level of dexterity required Recommended properties Impervious gloves in accordance with standard EN374 Body protection Avoid skin contact. Wear suitable protective clothing. Wear protective clothing against solid chemicals and particles suspended in the air (type 5) in accordance with standard EN to prevent skin contact. Work clothing worn by personnel shall be laundered regularly. After contact with the product, all parts of the body that have been soiled must be washed.

15 Section 8 Continued Respiratory protection Avoid breathing dust. If the ventilation is insufficient, wear appropriate breathing apparatus. When workers are confronted with concentrations that are above occupational exposure limits, they must wear a suitable, approved, respiratory protection device. Wear a disposable half mask dust filter in accordance with standard EN149. Category: FFPI Anti-gas and vapour filter(s) (Combined filters) in accordance with standard EN14387: A1 (Brown). SECTION 9: PHYSICAL AND CHEMICAL PROPERTIES 9.1. Information on basic physical and chemical properties General information: Physical state: powder or dust Important health, safety and environmental information: ph Not relevant. Boiling point/boiling range: Not relevant. Flash point interval: Not relevant. Vapour pressure: Not relevant. Water solubility: Soluble. Melting point/melting range: Not relevant 9.2. Other information SECTION 10: STABILITY AND REACTIVITY Reactivity Chemical stability This substance is stable under the recommended handling and storage conditions in section Possibility of hazardous reaction Conditions to avoid Dusts can form an explosive mixture with air.

16 Section 10 Continued 10.5 Incompatible materials 10.6 Hazardous decomposition products The thermal decomposition may release/form carbon monoxide (CO), carbon dioxide (CO2). SECTION 11: TOXICOLOGICAL INFORMATION Information on toxicological effects May cause irreversible damage to the skin; namely inflammation of the skin or the formation of erythema and eschar or oedema following exposure up to four hours Repeat or prolonged contact with the substance may cause removal of natural oil from the skin resulting in non-allergic contact dermatitis and absorption through the skin. May cause eye irritation which is totally reversible by the end of observation at 21 days. Respiratory tract irritation which occur, together with symptoms such as coughing, choking and breathing difficulties. Mixture No toxicological data available for the mixture SECTION 12: ECOLOGICAL INFORMATION Toxicity Substances No aquatic toxicity data available for the substance. Mixture No aquatic toxicity data available for the mixture Persistence and degradability Bio accumulative potential Mobility in soil Results of PBT and vpvb assessment Other adverse effects

17 SECTION 13: DISPOSAL CONSIDERATIONS Proper waste management of the substance and/or its container must be determined in accordance with directive 2008/98/EC Waste treatment methods Do not pour into drains or waterways Waste: Waste management is carried out without endangering human health, without harming the environment and, in particular without risk to water, air, soil, plants or animals. Recycle or dispose of waste in compliance with current legislation, preferably via a certified collector or company. Do not contaminate the ground or water with waste, do not dispose of waste into the environment. Soiled packaging: Empty containers completely. Give to a certified disposal contractor. SECTION 14: TRANSPORT INFORMATION Exempt from transport classification and labelling. Transport product in compliance with provisions of the ADR for road, RID doe rail, IMDG for sea and ISAO/IATA for air transport (ADR 2009 IMDG 2008 ICAO/IATA 2011) SECTION 15: REGULATORY INFORMATION Safety, health and environmental regulations/legislation specific for the substance or mixture -Particular provisions: 15.2 Chemical safety assessment.

18 Section 16 Other Information This advice is given by Cambridge Commodities Ltd who accept no legal liability for it. The information contained herein is based on the present state of our knowledge and is intended to describe our products from the point of view of safety requirements. It should not therefore be construed as guaranteeing specific properties. Individuals working with chemicals should consider all chemicals to be potentially hazardous even if their individual hazards may be uncharacterised or unknown. We confirm that the information above is sourced from the original manufacturers/suppliers Specification To be used as per local legislation Version No: 2