10 Mechanism, Structure, and Biological Role of Selenocysteine Lyase Hisaaki Mihara, Ryuta Tobe, and Nobuyoshi Esaki

Transcription

1 Contents Part I The Machinery of Selenoprotein Biosynthesis 1 Selenocysteine trna [Ser]Sec : From Nonsense Suppressor trna to the Quintessential Constituent in Selenoprotein Biosynthesis... 3 Bradley A. Carlson, Byeong Jae Lee, Petra A. Tsuji, Ryuta Tobe, Jin Mo Park, Ulrich Schweizer, Vadim N. Gladyshev, and Dolph L. Hatfield 2 Eukaryotic Mechanisms of Selenocysteine Incorporation and Its Reconstitution In Vitro Mark H. Pinkerton and Paul R. Copeland 3 Probing Selenoprotein Translation by Ribosome Profiling Michael T. Howard 4 Pathways in De Novo Biosynthesis of Selenocysteine and Cysteine in Eukaryotes Vadim N. Gladyshev, Bradley A. Carlson, and Dolph L. Hatfield 5 Prokaryotic Selenoprotein Biosynthesis and Function Michael Rother 6 The Role of Selenium in Human Evolution Louise White and Sergi Castellano 7 The Chemistry of Selenocysteine in Proteins Rebecca N. Dardashti, Linoy Dery, Reem Mousa, Shahar Dery, Post S. Reddy, and Norman Metanis 8 Evolution of Selenophosphate Synthetase Marco Mariotti, Didac Santesmasses, and Roderic Guigó 9 Structure and Mechanism of Selenocysteine Synthases Malgorzata Dobosz-Bartoszek and Miljan Simonović xvii

2 xviii Contents 10 Mechanism, Structure, and Biological Role of Selenocysteine Lyase Hisaaki Mihara, Ryuta Tobe, and Nobuyoshi Esaki Part II Selenoproteins, Their Occurrence and Function 11 Eukaryotic Selenoproteomes Vadim N. Gladyshev 12 Prokaryotic Selenoproteins and Selenoproteomes Yan Zhang 13 Functional Genomics of Selenoproteins and Se-responsive Pathways Catherine Méplan and John Hesketh 14 Selenium Regulation of the Selenoprotein and Non-selenoprotein Transcriptomes in a Variety of Species Roger A. Sunde Se NMR Spectroscopy of Selenoproteins Jun Liu and Sharon Rozovsky 16 Thioredoxin Reductase 1 as an Anticancer Drug Target Edward E. Schmidt and Elias S. J. Arnér 17 Basics and News on Glutathione Peroxidases Leopold Flohé and Regina Brigelius-Flohé 18 Glutathione Peroxidase Matilde Maiorino, Valentina Bosello-Travain, Giorgio Cozza, Giovanni Miotto, Laura Orian, Antonella Roveri, Stefano Toppo, Mattia Zaccarin, and Fulvio Ursini 19 The 15 kda Selenoprotein: Insights into Its Regulation and Function Bradley A. Carlson, Janelle M. Hartman, and Petra A. Tsuji 20 Selenoprotein K and Protein Palmitoylation in Regulating Immune Cell Functions Peter R. Hoffmann 21 Selenoprotein M: Structure, Expression and Functional Relevance Ting Gong, Marla J. Berry, and Matthew W. Pitts 22 Selenoprotein P and Selenium Distribution in Mammals Ulrich Schweizer, Lutz Schomburg, and Josef Köhrle

3 Contents xix 23 Selenoprotein T: From Discovery to Functional Studies Using Conditional Knockout Mice Loubna Boukhzar, Yannick Tanguy, Houssni Abid, Matthieu Castex, Abdallah Hamieh, Ifat Alsharif, Dorthe Cartier, Gaëtan Prevost, Anthony Falluel-Morel, Isabelle Lihrmann, Abdeslam Chagraoui, and Youssef Anouar 24 Biochemistry and Function of Methionine Sulfoxide Reductase Byung Cheon Lee Part III Dietary Selenium and Its Impact on Human Health 25 Selenium: Dietary Sources, Human Nutritional Requirements and Intake Across Populations Kristin M. Peters, Sarah E. Galinn, and Petra A. Tsuji 26 Human Clinical Trials Involving Selenium Lutz Schomburg 27 Status of Dietary Selenium in Cancer Prevention Gerald F. Combs Jr. and Lin Yan 28 Selenium in HIV/AIDS Adriana Campa, Sabrina Sales Martinez, and Marianna K. Baum 29 Genetic Variations in the Genes for Selenoproteins Implicate the Encoded Proteins in Cancer Etiology Rama Saad and Alan M. Diamond 30 Is Adequate Selenium Important for Healthy Human Pregnancy? Margaret P. Rayman 31 The Epidemiology of Selenium and Human Health Marco Vinceti, Barbara Burlingame, Tommaso Filippini, Androniki Naska, Annalisa Bargellini, and Paola Borella 32 Sex-Specific Differences in Biological Effects and Metabolism of Selenium Lutz Schomburg 33 Selenium and Endocrine Tissues Josef Köhrle 34 Selenium Antagonism with Mercury and Arsenic: From Chemistry to Population Health and Demography Anatoly V. Skalny, Margarita G. Skalnaya, Alexandr A. Nikonorov, and Alexey A. Tinkov 35 Biological Selenium Species and Selenium Speciation in Biological Samples Katarzyna Bierla, Joanna Szpunar, and Ryszard Lobinski

4 xx Contents Part IV Selenoproteins in Human Health 36 Selenoproteins in Nervous System Development, Function and Degeneration Ulrich Schweizer 37 Interplay of Selenoproteins and Different Antioxidant Systems in Various Cancers Petra A. Tsuji, Bradley A. Carlson, Byeong J. Lee, Vadim N. Gladyshev, and Dolph L. Hatfield 38 Glutathione Peroxidase 2, a Selenoprotein Exhibiting a Dual Personality in Preventing and Promoting Cancer Regina Brigelius-Flohé and Anna P. Kipp 39 Selenoproteins in Cardiovascular Redox Pathology Diane E. Handy and Joseph Loscalzo 40 What Do We Know About Selenium Contributions to Muscle Physiology? Alain Lescure, Mickaël Briens, and Ana Ferreiro 41 Tissue-Specific Regulation of Thyroid Status by Selenodeiodinases Alessandro Marsili, P. Reed Larsen, and Ann Marie Zavacki 42 The Role of Selenoproteins in Resolution of Inflammation Bastihalli T. Diwakar, Emily R. Finch, Chang Liao, Ashley E. Shay, and K. Sandeep Prabhu 43 Glutathione Peroxidase 4 and Ferroptosis José Pedro Friedmann Angeli, Bettina Proneth, and Marcus Conrad 44 Mutations in Humans That Adversely Affect the Selenoprotein Synthesis Pathway Erik Schoenmakers, Nadia Schoenmakers, and Krishna Chatterjee 45 Alteration of Selenoprotein Expression During Stress and in Aging Zahia Touat-Hamici, Yona Legrain, Jordan Sonet, Anne-Laure Bulteau, and Laurent Chavatte Part V Biological Models for Elucidating the Role of Selenium and Selenoproteins in Biology and Medicine 46 Selenocysteine trna [Ser]Sec Mouse Models for Elucidating Roles of Selenoproteins in Health and Development Bradley A. Carlson 47 Mouse Models that Target Individual Selenoproteins Marcus Conrad and Ulrich Schweizer

5 Contents xxi 48 The Naked Mole Rat and Selenium Alexei V. Lobanov and Vadim N. Gladyshev 49 Glutathione Peroxidase 1: Models for Diabetes and Obesity Xin Gen Lei and Marko Vatamaniuk 50 Selenium in Livestock and Other Domestic Animals Peter F. Surai and Vladimir I. Fisinin Index

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