cholinergic activation. European Journal of Pharmacology 468 (2) : Schimmer BP, Parker KL, Adrenocorticotropin Hormone; Adrenocortical

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1 DAFTAR PUSTAKA Armenia, Comparative Effectiveness of Defatted Hypotensive Crude Extract, Ethyl Acetate and Butanolic Fractions of Cassytha Filiformis L. on Different Models of Hypertensive Rats. World Journal of Pharmacy and Pharmaceutical Sciences 3(12): Armenia, Efek ekstrak butanol tali putri sebagai antikoagulan pada mencit putih jantan. Padang: Universitas Andalas (Unpublished). Armenia A, Munavvar AS, Abdullah N A, Helmi A, Johns ES The Contribution of Adrenoceptor Subtype(S) in the Renal Vasculature of Diabetic Spontaneously Hypertensive Rats. British Journal of Pharmacology 142(4): Atlas SA, The Renin-Angiotensin Aldosterone System: Pathophysiological Role and Pharmacologic Inhibition. Academy of Managed Care Pharmacy 13(8): Badyal DK, mh Lata and AP Dadhich, Animal Model of Hypertension and Effect of Drugs, Indian J. Pharmacol, 2003; 35: Balasuriya BWN, Rupasinghe HPV, Plant flavonoids as angiotensin converting enzyme inhibitors in regulation of hypertension. Functional Foods in Health and Disease 5: Beg M, Sharma V, Akthtar N, Gupta A, Mohd J, Role of Antioxidant in Hypertension. Journal Indian Academy of Clinical Medicine 12(2): Beevers G, Lip GYH, O Biren E, ABC of Hypertension : The Pathophysiology of Hypertension. British Medical Journal 322 (7291) : 912. Bergomi M, Rovesti S, Vinceti M, Vivoli R, Caselgrandi E, Vivoli G, Zinc and Copper Status and Blood Pressure. Journal of Trace Elements in Medicine and Biology 11(3): Charissa, N., Armenia, dan A. Bakhtiar Pengaruh gambir terstandardisasi terhadap tekanan darah, laju jantung dan volume urin tikus hipertensi. Skripsi Sarjana Farmasi, Universitas Andalas. Padang. Chobanian AV et al., The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure. Journal of the American Medical Association 289(19): Cowan MM, Plant Products as Antimicrobial Agents. Clinical Microbiology Reviews 12(4):

2 Dinas Kesehatan Kota Padang, Laporan Tahunan Tahun 2013 Edisi Juli. Padang. Dornas WC & ME Silva, Animal Model fot the Study of Hypertension, J. Biosci 36: Duarte J et al,., Antihypertensive effects of the flavonoid quercetin in spontaneously hypertensive rats. British Journal of Pharmacology 133: Fidan AF, Kucukkurt I, Yuksel H, Ozdemir A, Ince A, Dundar Y, The Effects of Structurally Different Saponin Containing Plants on Tissue Antioxidant Defense Systems, Lipid Peroxidation and Histopathological Change in Streptozocin-Induced Diabetic Rats. Journal of Animal and Veterinary Advences 8(5): Fidrianny I, Ayu D, Hartati R, Antioxidant capacities, phenolic, flavonoid and carotenoid content of various polarities extracts from three organs of Sechium edule (Jacq.) Swartz. Journal of Chemical and Pharmaceutical Research 7(5): Firdous SM, Sravanthi K, Debnath R, Neeraja K, Protective Efefect of Ethanolic Extract and its Ethylacetate and n-butanol Fraction of Sechium edule Fruits Against Tetrachloride Induced Hepatic Injury in Rat. International Journal of Pharmacy and Pharmaceutical Sciences 4(1): Gordon EA, Guppy LJ, Nelson M, The antihypertensive effects of the Jamaican Cho-Cho. West Indian Med J; 49: Gupta P, Bathia V, Corticosteroid Physiology and Principles of Therapy. Indian Journal of Pediatrics, 75 : Gusmelia, R., Armenia, dan Rusdi Hubungan efek penurunan tekanan darah dengan efek diuretic dari fraksi air daun tanaman akar mambu (Connarus grandis Jack.) terhadap tikus hipertensi. Skripsi Sarjana Farmasi, Universitas Andalas. Padang Guyton AC, Hall JE, Buku Ajar Fisiologi Kedokteran Edisi 11. Jakarta: Penerbit Buku Kedokteran EGC. Hedges LJ, Lister CE, Nutritional attributes of some exotic and lesser known vegetables. Plant & Food Research Confidential. January. New Zealand Herbie T, Kitab Tanaman Berkhasiat Obat.Yogyakarta : Penerbit OCTOPUS publishing house. Hirata Y, Satonaka H, Hypertension and Oxidative Stress. Japan Medical Association Journal, 44(12): ,

3 Hoffman BB, Therapy of Hypertension. Dalam (Brunton LL, Lazo JS and Parker KL Eds) Goodman & Gilman's The Pharmacological Basis Of Therapeutics - 11th Ed. San Diego, California : Mcgraw-Hil. James PA et al., Evidence-Based Guideline for the Management of High Blood Pressure in Adults: Report from the Panel Members Appointed to the Eighth Joint National Committee (JNC 8). Journal of the American Medical Association 311(5): Kementerian Kesehatan Republik Indonesia, Laporan Nasional Riset Kesehatan Dasar Desember. Jakarta. Kelly JJ, Tam SH, Williamson PM, Lawson J, Whitworth JA, The nitric oxide system and cortisol-induced hypertension in humas. Clin. Exp. Pharmacol. Physiol. 25(11), Kizhakekuttu TJ, Widlansky ME, Natural Antioxidant and Hypertension: Promise and Challenges. Cardiovascular Ther 28(4): Loizzo MR et al., Inhibition of Angiotensin Converting Enzyme (ACE) by Flavonoids isolated from Ailanthus excels (Roxb) (Simaroubaceae). Phytotherapy Research 21(1): Magen E, Viskoper RJ, Interactionc of Angiotensin-Converting Enzyme, Kinins and Nitric Oxide in Circulation and the Beneficial Effects of ACE Inhibitiom in Cardiovascular Disease. Israel Medical Association Journal 2(12): Maity S, Firdous SM, Debnath R, Evaluation of Antidiabetic Activity of Ethanolic Extract of Sechim Edule Fruits In Alloxan-Induced Diabetic Rats. World Journal of Pharmacy and Pharmaceutical Sciences. 2 (5): Marliana SD, Skrining Fitokimia dan Analisis Kromatografi Lapis Tipis Komponen Kimia Buah Labu Siam (Sechium edule Jacq. Swartz.) dalam Ekstrak Etanol. Biofarmasi 3 (1): MP System Hardware Guide,2015. BIOPAC System, Inc februari Na CS, Lee YH, Murai Y, Iwashina T, Kim TW, Hong SH, Flavonol 3,7- diglycosides from the aerial parts of Sicyos angulatus (Cucurbitaceae) in Korea and Japan. Biochemical Systematics and Ecology 48 (2013) Narayana KR, Reddy MS, Chaluvadi MR, Bioflavonoid and Classification, Pharmacological, Biochemical Effect and Therapeutic Potential. Indian Journal of Pharmacology 33: Nijveldt, Flavonoid : a review of probable mechanisms of action and potential applications. American Society for Clinical Nutrition 74:

4 Niu T, Thrasher KD, Gungy PD, Antioxidant Treatment Prevents Renal Damage and Dysfunction and Reduce Arterial Pressure in Salt- Sensitive Hypertension. Hypertension 2005; 45; 934 Oh H, Kang DG, Lee S, Lee Y, Lee HS, Angiotensin Converting Enzyme (ACE) inhibitory alkaloids from Fritillaria ussurensis. Planta Medica 69(6):564-5 Ordoñez AAL, Gomez JD, Cudmani NM, Vattuane MA and Isla MI, Antimicrobial Activity of Nine Extracts of Sechium edule (Jacq.) Swartz. Microbial Ecology in Health and Disease 15: Ordoñez, AAL, Gomez JD, Vattuone MA, Isla MI, Antioxidant activities of Sechium edule (Jacq.) Swart extracts. Food Chem 97, Paul AJ et al., Evidence-Based Guideline for the Management of High Blood Pressure in Adults: Report From the Panel Members Appointed to the Eighth Joint National Committee (JNC 8). Journal of the American Medical Association 311(5): Percival M, Antioxidants. Clinical Nutritional Insight 031(4):1-4. Plantamor, Plantamor Situs Dunia Tumbuhan, Informasi Spesies-labu. 2 Februari Prahasta A, Agribisnis Labu Siam. Bandung: Pustaka Grafika. Ragasa CY, Biona K, Shen CC, Chemical constituents of Sechium edule (Jacq.) Swartz. Der Pharma Chemica 6(5): Rilantono LL, Penyakit Kardiovaskular: 5 Rahasia. Jakarta: Badan Penerbit FKUI, hal Rizki A, The Miracle of Vegetables. Jakarta: Agromedia Pustaka. Rodriquez MS, Acosta H, Barroso C, 1984.Diuretic effect of chayote juice (Sechium edule) in rats. Rev Med Panama 9(1):68-94 Rozanna R, Potensi Tanaman Obat Sebagai Pangan Fungsional Mendorong Ekspor. Buku Panduan Seminar Nasional Tanaman Obat dan Obat Tradisional. BPPTO. Tawangmangu, Karanganyar, Surakarta. Jateng. Saruta T, Mechanism of Glucocorticoid-Induced Hypertension. Annual Meeting of The Japanese Society of Hypertension 19(1):1-8. Satttar, M.A. & Johns, E.J, Characteristics of a1-adrenoceptors in the rat renal vasculature. Br. J. Pharmacol., 104, 318P. Savci V, Goktalay G, Cansev V, Cavun S, Yilmaz MS, Ulus IH, Intravenously injected CDP-choline increases blood pressure and reverses hypotension in haemorrhagic shock: effect is mediated by central

5 cholinergic activation. European Journal of Pharmacology 468 (2) : Schimmer BP, Parker KL, Adrenocorticotropin Hormone; Adrenocortical Steroids and Their Synthetic Analogs; Inhibitors of The Synthesis and Actions of Adrenocortical Hormones. Dalam (Brunton LL, Lazo JS and Parker KL Eds) Goodman & Gilman's The Pharmacological Basis Of Therapeutics - 11th Ed. San Diego, California : Mcgraw-Hil. Sharon LHO, Whitworth JA, How do Glucocorticoid Cause Hypertension: Role of Nitric Oxide Deficiency, Oxidative Stress, and Eicosanoids. Endocrinol Metab Clin 40(2): Sherwood L, Fisiologi Manusia: dari Sel ke Sistem Edisi 6. Jakarta: Penerbit Buku Kedokteran EGC. Speisky H, Cassels BK, Lissi EA, Videla LA, Antioxidant Properties of The Alkaloid Boldine in Systems Undergoing Lipid Peroxidation and Enzyme Inactivation. Biochemical Farmacology 41(11) : Sulastri D, Rahmatini, Lipoeto NI, Edwar Z, The Role of Antioxidant Intake on enos3 Gene Expressionin Minangkabau Ethnic Grup Patient with Hypertension. Majalah Kedokteran Indonesia 60(12): Suryohudoyo P,1993. Oksidan, Antioksidan, dan Radikal Bebas.Surabaya. Thompson EB, Drug bioscreening. America: Graceway Publishing Company, Inc. 40 : 118. Tsao R, Chemistry and Biochemistry of Dietary Polyphenols. Nutrients 2: ; Vaziri,ND, Wang XQ, Oveisi F and Rad B, Determining the antioxidant activity of certain medicinal plants of Sonitpur (Assam), India using DPPH assay. J Phytol. 1(1): Victor RG, Systemic Hypertension : Mechanism and Diagnosis in : Braunwald s heart disease : A text book of cardiovascular medicine, Braunwald s, E., et al (Ed). Philadelphia : Elsevier. pp Wei T, Chen C, Hou J, Xin W, Mori A, Nitric Oxide induces oxidative stress and apoptosis in neuronal cells. Biochimica et Biophysica Acta. Elsevier. Pp Whitworth JA, Mechanisms of Glucocorticoid-induced Hypertension. Kidney International 31(5): Wink DA, Miranda KM, Espey MG, Pluta RM, Hewett SJ, Colton C, Feelish M, Grishman MB. Mechanisme pf the antioxidant effect of nitric oxide. Antioxid Redox Signal 3(2):203-13

6 World Health Organization, A global brief on Hypertension. ertension/en/. 24 Juli 2015 (14.20). Xiao J, Jiang X, Chen X, Antibacterial, Anti-inflammatory and Diuretic Effect of Flavonoids From Marchantia Convoluta. African Journal of Traditional, Complementary and Alternative Medicines 2(3): Yogiantoro M, Hipertensi Essensial. Dalam (Sudoyo AW, Setiyohadi B, Idrus A, Simadibrata M, Setiati S ed) Buku Ajar Penyakit Ilmu Penyakit Dalam. Jakarta: InternaPublishing, hal Yuliandra Y, Armenia, Arifin H, Studi Efek Antihipertensi Tumbuhan Tali Putri (Cassytha Filiformis L.) pada Tikus Hipertensi yang Diinduksi Prednison dan Garam. Prosiding Seminar Nasional Perkembangan Terkini Sains Farmasi dan Klinik III. Zhang Y, Croft KD, Mori TA, Schyvens CG, McKenzie KU, Whitworth JA,2004. The antioxidant tempol prevents and partially reverse dexamethasoneinduced hypertension in the rat. Am. J. Hypertens. 17(3);

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