JOINT FAO/WHO MEETING ON FOOD ADDITIVES (JECFA) 7-16 June 2016

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1 JOINT FAO/WHO MEETING ON FOOD ADDITIVES (JECFA) 7-16 June 2016 List of WHO experts For FAO experts please refer to the FAO JECFA website: BARLOW Sue Brighton, East Sussex UK Sue Barlow has been involved in risk assessment of chemicals and food for many years. In her early career in academia she worked in reproductive/developmental toxicology research and taught pharmacology. She then worked in regulatory toxicology in the UK Department of Health and became chief scientist. Since 1996, she has been an independent consultant in toxicology. She has been a temporary adviser to JECFA since 2005 and a member of the WHO Expert Advisory Panel on Food Safety since She was involved in the preparation of the 2009 FAO/WHO guide to JECFA and JMPR Principles and Methods for the Risk Assessment of Chemicals in Food and was a coeditor of the 2002 IPCS-WHO/ILO/UNEP Global Assessment of the State-of-the Science of Endocrine Disrupters. She was a member Veterinary International Cooperation on Harmonisation Safety Working Group. She is an evaluator and reviewer for research proposals and projects funded by European Commission. She was a member of the European Commission s Scientific Committee on Food for 10 years. From she chaired the European Food Safety Authority s Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food. She was a member of EFSA s Scientific Committee from BENFORD Diane UK Food Standards Agency, London UK Dr Diane Benford is head of the Risk Assessment Unit at the UK Food Standards Agency. The Unit has overall responsibility for advice on risks associated with all types of chemicals in food and of microbial food contamination, but much of Diane s work focuses on chemical contaminants, food additives and natural toxicants. Diane s background is in toxicology, with particular expertise in mechanisms of toxicity and risk assessment. Her role at the Food Standards Agency also includes acting as scientific secretary to the Committee on Toxicity of Chemicals in Food, Consumer Products and 1

2 the Environment (COT) and part of the joint secretariat to its sister committee on Mutagenicity (COM) and Carcinogenicity (COC). In a personal capacity, Diane was a member of the scientific panel on contaminants in the food chain [CONTAM] of the European Food Safety Authority (EFSA) from 2006 to 2015, acting as chair of the panel for the final 3 year term of office. She is now a member of the EFSA Scientific Committee. She has participated in meetings of JECFA since 2001, firstly as a WHO Temporary Advisor and since 2013 as a member. FEELEY Mark Bureau of Chemical Safety, Food Directorate, Health Canada, Ottawa Canada Mark Feeley is the Associate Director, Bureau of Chemical Safety, Food Directorate, Health Products and Food Branch, Health Canada. The Bureau of Chemical Safety of Health Canada is responsible for policy, standard setting, risk assessment, research and evaluation activities with respect to chemicals in foods in Canada. Major programs for the Bureau of Chemical Safety include food additives, food contaminants (natural and anthropogenic), food packaging materials, food allergens and Novel foods, including GMOs. Mr. Feeley also serves as the chair of the Health Canada Animal Care Committee. Mark Feeley is currently the Head of the Canadian delegation for the Codex Committee on Contaminants in Food (CCCF), a member of both the Joint FAO/WHO Expert Committee on Food Additives (JECFA) Roster of Toxicological and Epidemiological Experts and of the World Health Organization Expert Advisory Panel on Food Safety. Mr. Feeley has published over 75 original research articles/book chapters on topics ranging from the safety assessment of food additives to human biomarkers for chemical contaminants. He has also been an invited expert to a number of international consultations dealing with various chemical food safety topics including melamine, BPA, Dioxins and Risk:Benefit analysis of fish consumption. Mr. Feeley is currently an associate editor with the journal Food and Chemical Toxicology. FIELDS Barry BSc, PhD Food Standards Australia New Zealand, Barton, ACT, Australia Dr Barry Fields is a Senor Toxicologist in the Risk Assessment Chemical Safety and Nutrition Section at Food Standards Australia New Zealand. Barry Fields completed a PhD in chemistry in 1993 at the University of Sydney, followed by postdoctoral research at the Center for Advanced Research in Biotechnology (now the Institute for Bioscience and Biotechnology Research, University of Maryland) and then returned to the University of Sydney in 1997 as a Senior Research Fellow. Barry joined the Therapeutic Goods Administration in 2003 as a Senior Toxicologist assessing data to support the approval of therapeutic drugs. Since joining FSANZ in 2008, Barry has contributed to safety/risk assessments of food additives, contaminants, processing aids, nutritive substances, novel foods and natural toxicants. In 2011, he was appointed as a temporary adviser on the JECFA roster of toxicological and epidemiological experts. 2

3 GILLESPIE Zoe Health Canada, Ottawa, Ontario, Canada Ms. Gillespie has been a Senior Scientific Advisor for the Bureau of Chemical Safety, in the Food Directorate at Health Canada since January In this position, Ms. Gillespie is responsible for coordinating research and regulatory initiatives for priority setting and providing toxicology expertise for risk assessments of chemicals in food. Ms. Gillespie joined Health Canada in 2002 after obtaining her BSc Honours from the University of Guelph with a specialization in Biomedical Toxicology, gaining over a decade of extensive experience as a regulatory toxicologist and conducting risk assessments on pesticides, food additives, genetically modified foods, food contact materials, food contaminants and natural toxins. HILL Frances UK Food Standards Agency, London UK Mrs Frances Hill works as a toxicologist in the Chemical Risk Assessment Unit at the UK Food Standards Agency. The Unit has overall responsibility for advice on possible adverse human health effects of all types of chemicals in food, but she works specifically on food additives and flavourings, novel foods, natural toxicants and dietary supplements. In her role, she provides advice to the public and risk assessments to support the work of other government departments and policy colleagues. Frances is a member of the Secretariat for the UK Committee on Toxicity of Chemicals in Food, Consumer Products and the Environment (COT) and part of the joint secretariat for its sister Committees the Committee on Carcinogenicity (COC) and the Committee on Mutagenicity (COM). Between 2006 and 2013, she was also a member of the European Food Safety Authority (EFSA) working group on flavourings, contributing to drafting opinions for consideration by the EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF Panel). She has worked previously with JECFA experts on steviol glycosides (addendum) in 2007 and acidified sodium chlorite in She completed a BSc. in Biological Sciences at Lancaster University and an MSc. in Toxicology at the University of Birmingham. JIA Xudong China National Center for Food Safety Risk Assessment, Beijing, China Xudong Jia is a research professor of China National Centre for Food Safety Risk Assessment (CFSA). Dr Jia currently serves as Director of Laboratory of Toxicology. Dr Jia received a MD degree from Shandong Medical University in 1996 and a PhD in Nutrition and Food Hygiene from Chinese Academy of Preventive Medicine in He worked at Tufts University as a visiting scientist during , and at World Health Organization as a P4 technical officer from Dr Jia has over 15 years experience in research on Food Toxicology including toxicological safety evaluation on food and preventive effect of phytochemicals on chronic diseases. In recent years, his 3

4 research has focused on risk assessment techniques on food safety. Dr Jia has participated several projects including the GMO project, National Natural Science Foundation project and several international cooperative projects. He received a Scientific and Technological Progress Award in 2004 and 2011 respectively. Dr Jia has published more than 100 scientific papers in peer-reviewed scientific journals. Dr Jia is a member of the National Food Safety Standard Review Committee, a member of National Agricultural GMO Safety Committee, and a member of Chinese Society of Toxicology. MATTIA Antonia Food and Drug Administration, College Park, MD USA Dr. Antonia Mattia earned her Ph.D. degree in pharmacology in 1985 at the University of Maryland, Baltimore, MD. Before joining the Food and Drug Administration in 1991, she was a Research Associate in the Department of Pharmacology, College of Medicine, at the University of Arizona Health Sciences Center, Tucson, AZ. Dr. Mattia has been a toxicology reviewer, team leader and supervisor in the Center for Food Safety and Applied Nutrition (CFSAN), resulting in more than two decades of hands on experience in the safety assessment of food ingredients and contaminants. Since 2002, Dr. Mattia has served as the Director of the Division of Biotechnology and GRAS Notice Review in the Office of Food Additive Safety in CFSAN. In this position, Dr. Mattia is responsible for the technical evaluations of regulatory and scientific issues regarding direct food ingredients and plants that are bioengineered for food uses. MULDOON JACOBS Kristi Food and Drug Administration, College Park, MD USA Dr. Kristi Muldoon Jacobs earned her Ph.D. degree in 2006 Molecular Genetics, Microbiology & Immunology at the University of Medicine and Dentistry of New Jersey, Graduate School of Biomedical Sciences. Before joining the Food and Drug Administration in 2008, she was a fellow at the National Institute of Health, National Cancer Institute in the Radiation Oncology Branch. Dr. Muldoon Jacobs has been a toxicology reviewer, team leader and supervisor in the Center for Food Safety and Applied Nutrition (CFSAN), resulting in nearly a decade of hands on experience in the safety assessment of food ingredients and food contact materials. Since 2013, Dr. Muldoon Jacobs has served as the Toxicology Supervisor of the Division of Food Contact Notifications in the Office of Food Additive Safety in CFSAN. In this position, Dr. Muldoon Jacobs is responsible for the toxicology and safety evaluation of indirect additives including food contact substances, processing aids, antimicrobials along with their impurities, and constituents. PASCAL Gérard Saint Alyre d Arlanc, France 4

5 Gérard Pascal, engineer in biochemistry, has been head of department then scientific director for human nutrition and food safety at the French Research Institute on Agriculture (INRA). In his early career he worked on safety assessment of antioxidant food additives, on nutritional requirement of poly-unsaturated fatty acids in the perinatal period and on the relationship between food and xenobiotics toxicity. Since 2008, he has been an independent consultant in nutrition and toxicology. More than 150 publications in peer-reviewed scientific journals and book chapters. He was consulting professor at ENSIA (Engineer school on food industry) for 20 years. He chaired the nutrition section of the Conseil supérieur d hygiène publique de France and the scientific board of Agence Française de Sécurité Sanitaire des Aliments (AFSSA). He was ( ) member and chair of several scientific committees at EU level: Scientific Committee for Food, Multidisciplinary Committee on BSE, Scientific Steering Committee and panels at European Food Safety Authority (EFSA). He was co-author of reports at the origin of AFSSA and EFSA. He has been WHO Member of JECFA for the first time in 1993 and since participated in 13 of its meetings. PAUMGARTTEN Francisco National School of Public Health, FIOCRUZ, Rio de Janeiro Brazil Francisco Paumgartten is full professor (Toxicology and Environmental Health) at the National School of Public Health (Oswaldo Cruz Foundation - FIOCRUZ, Ministry of Health - Brazil). Prof. Paumgartten studied Medicine (Federal University of Rio de Janeiro, 1974), earned his PhD degree in Pharmacology at Paulista School of Medicine (Federal University of São Paulo, 1983) and had a post-doc training in Toxicology at the Institute of Embryopharmacology and Toxicology (Freie Universitaet Berlin, 1989). Currently, he is the leader of a research group on Environmental Health and Toxicology and the head of the Laboratory of Environmental Toxicology at FIOCRUZ, and a member of the Technical Chamber of Medicines (CATEME) of the Brazilian National Health Surveillance Agency (ANVISA). Paumgartten served as an Editorial board member of the Journal of Environmental Science and Health Part A ( ) and of Reproductive Toxicology ( ). He has published over 150 papers in scientific journals most of which in the areas of chemical and drug safety, reproductive and developmental toxicology, genetic toxicology, xenobiotic metabolism and toxicokinetics. PRONK Marja National Institute for Public Health and the Environment (RIVM), Bilthoven The Netherlands Marja Pronk is a senior toxicologist at the Centre for Safety of Substances and Products in RIVM, with a background in toxicology and human nutrition. She has more than 25 years of hands-on experience in policy advice on human toxicology and risk assessment of chemicals, both food- and non-food related (such as veterinary drugs, novel foods, food additives, industrial chemicals, nanomaterials). Over the years she has contributed to the development and improvement of methodologies and guidance for human health risk assessment, and participated in several national and international expert (working) 5

6 groups and meetings. Currently she is member of the Committee for Risk Assessment (RAC) of the European Chemicals Agency (ECHA) since its start in She has participated as temporary adviser in meetings of JECFA since 1996, first on veterinary drugs, later on food additives. SCHLATTER Josef Zürich Switzerland Josef Schlatter has been toxicologist for 28 years at the Nutritional and Toxicological Risks Section of the Swiss Federal Office of Public Health, Food Safety Division, and was the head of the section for 21 years until his retirement in The main responsibility of the section was performing risk assessments in the area of diet and nutrition and all types of chemicals in food. These include natural toxicants, contaminants in food and drinking water (residues of veterinary drugs, pesticides, environmental pollutants), food additives, cosmetics, food contact materials and toxicological evaluation of novel foods. His research focussed mainly on natural toxicants (inherent food-plant toxins, mycotoxins) and contaminants. He was a lecturer in toxicology for more than 10 years at the Swiss Federal Institute of Technology, Zürich and was teaching/organising block courses in food toxicology. In a personal capacity, he has been a member of the Scientific Committee on Food of the European Commission and was chairing the scientific panel on contaminants in the food chain of the European Food Safety Authority for 9 years ( ), and is currently member of the EFSA Scientific Committee. He has participated in about 20 meetings of JECFA since SIPES Glenn Department of Pharmacology, College of Medicine, University of Arizona USA Dr. I. Glenn Sipes is Professor Emeritus at the University of Arizona. His research program focused on the biotransformation of xenobiotics and on chemical-induced liver and ovarian injury. He authored over 250 research publications and was a co-editor-in- Chief of Comprehensive Toxicology. For 29 years he served as Head of Pharmacology and Toxicology in the College of Pharmacy and Head of Pharmacology in the College of Medicine. During that time he was the founding Director of both the Center for Toxicology and the Southwest Environmental Health Sciences Center. Dr. Sipes participated in a number of professional/scientific organizations. For the Society of Toxicology he served President and as Editor of Toxicology and Applied Pharmacology. He was also President of the International Union of Toxicology. He was a member of the National Academy of Sciences Committee of Toxicology as well as its Board of Environmental Studies and Toxicology and was a member of the National Advisory Environmental Health Sciences Council (NIEHS). Dr. Sipes was elected a Fellow of AAAS and of the Academy of Toxicological Sciences for which he served as President. For 20 years he has been a technical advisor to JECFA and a member and Chair of the Research Institute for Fragrance Material s Expert Panel. Recent honors include the 6

7 2011 Distinguished Scientist Award from the American College of Toxicology, 2015 Mildred S. Christian Career Achievement Award from The Academy of Toxicological Sciences and the 2016 Society of Toxicology Distinguished Toxicology Scholar Award. Utz MUELLER Food Standards Australia New Zealand, Barton, ACT, Australia Dr Utz Mueller is the Principal Toxicologist and Manager of the Risk Assessment Chemical Safety and Nutrition Section in Food Standards Australia New Zealand. Prior to joining FSANZ in 2006 he was the Chief Scientist in the Office of Chemical Safety with responsibility for toxicological assessments of pesticides. Dr Mueller holds a Bachelor of Science (Hons) and PhD in Pharmacology from the University of Western Australia, Perth, WA. Dr Mueller was a Senior Research Fellow at Flinders University in South Australia prior to joining the Therapeutic Goods Administration in 1996 where his primary task was the safety evaluation of pre-market therapeutic drugs. He subsequently joined the Office of Chemical Safety in 1997 to undertake pre-market safety assessments and review the safety of existing agricultural and veterinary chemicals. He has also been a scientific advisor for the FAO/WHO Joint Meeting on Pesticide Residues (JMPR) and Joint Expert Committee of Food Additives (JECFA) for several years. He is currently a JECFA panel member. WILLIAMS Gary Department of Pathology, New York Medical College, New York USA Gary Williams, M.D. is Professor of Pathology and Professor of Clinical Public Health at New York Medical College, Valhalla, NY. Dr. Williams received the Batchelor of Arts degree from Washington and Jefferson College, Washington, PA. and earned the Doctor of Medicine from the University of Pittsburgh School of Medicine, Pittsburgh, PA. He trained in pathology at the Massachusetts General Hospital, Boston, MA., and Temple University Hospital, Philadelphia, PA. He is certified by the American Board of Pathology, the American Board of Toxicology, and is a Fellow in Toxicologic Pathology of the International Academy of Toxicologic Pathology and a Fellow of the Royal (U.K.) College of Pathologists. He was made an Honorary Member of the American College of Veterinary Pathologists. Dr. Williams has received several awards, including the Arnold J. Lehman (1982), Enhancement of Animal Welfare (2002) and Merit (2009) Awards from the Society of Toxicology, the 2001 Ambassador in Toxicology from the Mid- Atlantic Chapter of the Society of Toxicology and was designated Distinguished Scientist 2005 by the American Chemical Society, Westchester Chemical Society. In 2005 he received the Dean s Distinguished Research Award from New York Medical College. His research focuses on chemical toxicology and carcinogenesis, on which he has authored or coauthored 533 papers. 7

8 YANG Xingfen Guangdong Provincial Center for Disease Control and Prevention, Guangzhou, P.R.China Dr. Xingfen Yang received her Medical Degree and Ph.D. in toxicology from School of Public Health, Sun Yat-Sen University [formerly Sun Yat-Sen University of Medical Sciences (SUMS)]. In 1994 and 1996, she was a visiting scholar at COFM, National University of Singapore. She has served as a Lecturer, Associate Professor and Professor in School of Public Health, SUMS from 1984 to She is now the chief scientist of Guangdong Provincial Center for Disease Control and Prevention, China. She has been deputy director of Guangdong CDC since 2001, where she is mainly engaged in research of applied toxicology and food safety surveillance and risk assessment. Dr. Yang has been a WHO expert of JECFA since She is currently a member of National Expert Committee for Food Safety Risk Assessment, Vice Chairman of Chinese Society of Toxicology (CSOT) and Professional Committee of Food Toxicology, Committee of Alternatives and Translational Toxicology, CSOT. Currently, her research interests focus on the risk assessment of food contaminants and additives (e.g cadmium, mercury), and alternative methods to animal tests of toxicological safety evaluation. YOON Hae Jung Ministry of Food and Drug Safety Republic of Korea Dr Hae Jung Yoon is Director of the Food Standard Division at the Ministry of Food and Drug Safety in Republic of Korea. Yoon earned her Ph.D in Chemistry in 1995 at Ewha Womans University, Republic Korea and her work has focused on chemical risk assessment that encompasses monitoring/surveying chemicals in food (food additives, contaminants, pesticides, and packaging materials). Dr Yoon has been participated FAO/WHO Roster of experts for JECFA for exposure assessment of chemicals in food since 2006 and involved other international activities including WHO Expert meeting for Toxicological and Health Aspects of Melamine and Cyanuric acid in 2008 and preparation of Environmental Health Criteria for Dermal Exposure in Disclaimer: In order to enhance its management of Conflicts of Interest as well as strengthen public trust and transparency in connection with WHO meetings involving the provision of technical/normative advice, the names and brief biographies of individuals ( Published Information ) being considered for participation in such meetings are disclosed for public notice and comment. The Published Information is provided by the experts themselves and is the sole responsibility of the individuals concerned. WHO is not responsible for the accuracy, veracity and completeness of the Published Information provided. Furthermore, in no event will WHO be responsible or liable for damages in relation to the use of, and reliance upon, the Published Information. 8

9 The comments received by WHO through the public notice and comment process are treated confidentially and their receipt will be acknowledged through a generic notification to the sender. Comments and perceptions brought to the knowledge of WHO through this process are an integral component of WHO s conflict of interest assessment policy and are carefully reviewed. WHO reserves the right to discuss information received through this process with the relevant expert with no attribution to the provider of such information. Upon review and assessment of the information received through this process, WHO, in its sole discretion, may take appropriate management action in accordance with its policies. The participation of an expert in a WHO meeting does not imply that they are endorsed or recommended by the World Health Organization nor does it create a binding relationship between the expert and WHO. The list of participating experts, a summary of relevant interests disclosed by such experts, and any appropriate mitigation measures taken by WHO relating to the management of conflicts of interests, will be reported publically in accordance with WHO practice. Send your comments to: jecfa@who.int 9

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