April 28, RE: Immediate Action test change notification. Dear Valued Client:
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- Bernice Phelps
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1 April 28, 2010 RE: Immediate Action test change notification Dear Valued Client: The following pages detail important information regarding a test requiring database modifications. Please be advised that this urgent change is effective. Please use this packet of information to update your computer systems/records. This change is important to ensure standardization of our mutual laboratory databases. If you have any questions about the information contained in this packet, please call our Client Support Department at (866) Thank you for your continued support of and your assistance in implementing this change. Sincerely, 3701 Welsh Road, Willow Grove, Pennsylvania T F
2 Database Changes - Summary New Name Scope Specimen Stability Discontinued Reference Reqs comment 3996SP Bufotenine/Psilocybin, Serum/Plasma 3996U Bufotenine/Psilocybin Metabolite, Urine 4027SP Psilocybin Metabolite, Serum/Plasma 4027TI Psilocybin Metabolite, Tissue 4027U Psilocybin Metabolite, Urine 5496U Bufotenine/Psilocybin Metabolite Confirmation, Urine Psilocybin Metabolite Confirmation, Serum/Plasma 5570SP (Forensic) Drug Impaired Driving/DRE Toxicology 8074U Hallucinogens Add-On, Urine (Forensic) 8760SP Hallucinogens Profile, Serum/Plasma (Forensic) 8760U Hallucinogens Profile, Urine (Forensic) Misc. Page 1
3 NEW TESTS 5570SP Name Reporting Limit Psilocybin Metabolite Confirmation, Serum/Plasma (Forensic) Units Method / CPT Scope of Analysis: Psilocin 2.5 ng/ml LC-MS/MS (82542) Psilocin, the dephosphorylated, pharmacologically active hallucinogenic component of psilocybin, is usually present in lesser amounts in certain species of mushrooms and it is formed in the body as a metabolite following psilocybin ingestion. Specimen Requirements: Specimen Requirements: 5 ml Serum or Plasma Special Handling: Promptly centrifuge and separate Serum or Plasma into a plastic screw capped vial using approved guidelines. Rejection Criteria: Not received Light Protected. Received Room Temperature. Received Refrigerated. Polymer gel separation tube (SST or PST). Stability: Room Temperature: Not Stable Refrigerated: Not Stable Frozen (-20 C): 1 day(s) The CPT s provided in this document are based on AMA guidelines and are for informational purposes only. NMS Labs does not assume responsibility for billing errors due to reliance on the CPT s listed in this document. Page: 2
4 Method/CPT *, Units of Measurement, Scope of Analysis and Specimen Requirements Name Units Method / CPT 5496U Bufotenine/Psilocybin Metabolite Confirmation, Urine Scope of Analysis: Bufotenine 5.0 ng/ml LC-MS/MS (83789) Bufotenine is a tryptamine alkaloid found in the skin of some species of toads, mushrooms, and higher plants. It has hallucinogenic properties. Psilocin Total 5.0 ng/ml This analysis reports the total of unconjugated plus conjugated Psilocin. Specimen Requirements: Specimen Requirements: 3 ml Urine Special Handling: None Rejection Criteria: Not received Light Protected. Received Room Temperature. Received Refrigerated. Stability: Room Temperature: Not Stable Refrigerated: Not Stable Frozen (-20 C): Not Stable Reference comments were changed. Requested volume was changed. Transport Temperature was changed. The CPT s provided in this document are based on AMA guidelines and are for informational purposes only. NMS Labs does not assume responsibility for billing errors due to reliance on the CPT s listed in this document. Page: 3
5 Method/CPT *, Units of Measurement, Scope of Analysis and Specimen Requirements Name Units Method / CPT 8074U Drug Impaired Driving/DRE Toxicology Hallucinogens Add-On, Urine (Forensic) Specimen Requirements: Specimen Requirements: 9 ml Urine Special Handling: Glass containers are not acceptable. Rejection Criteria: Not received Light Protected. Glass container. Stability: Room Temperature: Undetermined Refrigerated: Undetermined Frozen (-20 C): Undetermined Requested volume was changed. Transport Temperature was changed. The CPT s provided in this document are based on AMA guidelines and are for informational purposes only. NMS Labs does not assume responsibility for billing errors due to reliance on the CPT s listed in this document. Page: 4
6 Method/CPT *, Units of Measurement, Scope of Analysis and Specimen Requirements Name Units Method / CPT 8760SP Hallucinogens Profile, Serum/Plasma (Forensic) Compound: Psilocin 2.5 ng/ml LC-MS/MS (83789) Psilocin, the dephosphorylated, pharmacologically active hallucinogenic component of psilocybin, is usually present in lesser amounts in certain species of mushrooms and it is formed in the body as a metabolite following psilocybin ingestion. Specimen Requirements: Specimen Requirements: 10 ml Serum or Plasma Special Handling: Glass containers are not acceptable. Collect sample in Gray top tube (Sodium Fluoride / Potassium Oxalate). Promptly centrifuge and separate Serum or Plasma into a plastic screw capped vial using approved guidelines. Rejection Criteria: Not received Light Protected. Glass container. Polymer gel separation tube (SST or PST). Stability: Room Temperature: Undetermined Refrigerated: Undetermined Frozen (-20 C): Undetermined Bufotenine was removed. Reference comment was changed. Psilocin: Confirmation testing is automatically performed on all positive findings [Confirmation Acode: 5570SP] The CPT s provided in this document are based on AMA guidelines and are for informational purposes only. NMS Labs does not assume responsibility for billing errors due to reliance on the CPT s listed in this document. Page: 5
7 Method/CPT *, Units of Measurement, Scope of Analysis and Specimen Requirements Name Units Method / CPT 8760U Hallucinogens Profile, Urine (Forensic) Scope of Analysis: Bufotenine 5.0 ng/ml LC-MS/MS (83789) Bufotenine is a tryptamine alkaloid found in the skin of some species of toads, mushrooms, and higher plants. It has hallucinogenic properties. Scope of Analysis: Psilocin - Total 5.0 ng/ml This analysis reports the total of unconjugated plus conjugated Psilocin. Specimen Requirements: Specimen Requirements: 10 ml Urine Special Handling: Glass containers are not acceptable. Rejection Criteria: Not received Light Protected. Glass container. Stability: Room Temperature: Undetermined Refrigerated: Undetermined Frozen (-20 C): Undetermined Reference comments were changed. Requested volume was changed. Transport Temperature was changed. DISCONTINUED TESTS Name Alternative 3996SP Bufotenine/Psilocybin, Serum/Plasma No alternate test available 3996U Bufotenine/Psilocybin Metabolite, Urine No alternate test available 4027SP Psilocybin Metabolite, Serum/Plasma No alternate test available 4027TI Psilocybin Metabolite, Tissue No alternate test available 4027U Psilocybin Metabolite, Urine No alternate test available The CPT s provided in this document are based on AMA guidelines and are for informational purposes only. NMS Labs does not assume responsibility for billing errors due to reliance on the CPT s listed in this document. Page: 6
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