Test Definition: IGFG Insulin-Like Growth Factor 1 (IGF-1) and Insulin-Like Growth Factor Binding Protein 3 (IGFBP-3) Growth Panel

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Sherman Fisher
5 years ago
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Reporting Title: IGF-1 and IGFBP-3 Growth Panel Performing Location: Rochester Specimen Requirements: Collection Container/Tube: Preferred: Red top Acceptable: Serum gel Submission Container/Tube:

1 Reporting Title: IGF-1 and IGFBP-3 Growth Panel Performing Location: Rochester Specimen Requirements: Collection Container/Tube: Preferred: Red top Acceptable: Serum gel Submission Container/Tube: Plastic vial Specimen Volume: 1 ml Collection Instructions: Spin down promptly. Aliquot into two equal portions. Additional Information: Indicate patient's age and sex. Specimen Type Temperature Time Serum Frozen 14 days Result Codes: Result ID Reporting Name Type Unit LOINC IGF1I Insulin-Like Growth Factor 1, S Numeric ng/ml In Process IGFB3 IGFBP-3, S Numeric mcg/ml Also used by tests: IGFB3 Components: Test ID Reporting Name CPT Units CPT Code Always Performed Orderable Separately IGF1I Insulin-Like Growth Factor 1, S Yes Yes IGFB3 IGFBP-3, S Yes Yes Reference Values: Males: Age ng/ml 0.1 Percentile (ng/ml) 0-11 months Document generated January 22, 2013 at 4:31pm CST Page 1 of 5

2 1 year years years years years years years years years years years years years years years years years years years years years years years years years years years years years years years years Document generated January 22, 2013 at 4:31pm CST Page 2 of 5

3 80-85 years years Females: Age ng/ml 0.1 Percentile (ng/ml) 0-11 months year years years years years years years years years years years years years years years years years years years years years years years years years years Document generated January 22, 2013 at 4:31pm CST Page 3 of 5

4 51-55 years years years years years years years years Reference values have not been established for patients that are >90 years of age. IGF-1 reference values according to Tanner stages I-V(2) Males - Stage I: ng/ml - Stage II: ng/ml - Stage III: ng/ml - Stage IV: ng/ml - Stage V: ng/ml Females - Stage I: ng/ml - Stage II: ng/ml - Stage III: ng/ml - Stage IV: ng/ml - Stage V: ng/ml Note: Puberty onset, ie the transition from Tanner stage 1 (prepubertal) to Tanner stage 2 (early pubertal), occurs for girls at a median age of 10.5 (+/- 2) years and for boys at a median age of 11.5 (+/-2) years. There is evidence that it may occur up to 1 year earlier in obese girls and in African-American girls. By contrast, for boys there is no definite proven relationship between puberty onset and body weight or ethnic origin. Progression through Tanner stages is variable. Tanner stage 5 (young adult) should be reached by age 18. INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN days: < or =0.7 mcg/ml 8-14 days: mcg/ml 15 days-11 months: unavailable 1 year: mcg/ml 2 years: mcg/ml 3 years: mcg/ml 4 years: mcg/ml 5 years: mcg/ml 6 years: mcg/ml 7 years: mcg/ml 8 years: mcg/ml 9 years: mcg/ml 10 years: mcg/ml 11 years: mcg/ml 12 years: mcg/ml Document generated January 22, 2013 at 4:31pm CST Page 4 of 5

5 13 years: mcg/ml 14 years: mcg/ml 15 years: mcg/ml 16 years: mcg/ml 17 years: mcg/ml 18 years: mcg/ml 19 years: mcg/ml 20 years: mcg/ml years: mcg/ml years: mcg/ml years: mcg/ml years: mcg/ml years: mcg/ml years: mcg/ml years: mcg/ml years: mcg/ml years: mcg/ml years: mcg/ml years: mcg/ml years: mcg/ml years: mcg/ml Tanner Stages: Males Stage I: mcg/ml Stage II: mcg/ml Stage III: mcg/ml Stage IV: mcg/ml Stage V: mcg/ml Females Stage I: mcg/ml Stage II: mcg/ml Stage III: mcg/ml Stage IV: mcg/ml Stage V: mcg/ml Note: Puberty onset, ie the transition from Tanner stage 1 (prepubertal) to Tanner stage 2 (early pubertal), occurs for girls at a median age of 10.5 (+/- 2) years and for boys at a median age of 11.5 (+/-2) years. There is evidence that it may occur up to 1 year earlier in obese girls and in African-American girls. By contrast, for boys there is no definite proven relationship between puberty onset and body weight or ethnic origin. Progression through Tanner stages is variable. Tanner stage 5 (young adult) should be reached by age 18. Document generated January 22, 2013 at 4:31pm CST Page 5 of 5

Result ID Reporting Name Type Unit LOINC. Z1886 Cortisol Alphanumeric ug/dl Z0226 Deoxycorticosterone (DOC) Alphanumeric ng/dl

Result ID Reporting Name Type Unit LOINC. Z1886 Cortisol Alphanumeric ug/dl Z0226 Deoxycorticosterone (DOC) Alphanumeric ng/dl Reporting Title: CAH Profile 6 Performing Location: Esoterix Endocrinol Specimen Requirements: Draw blood in a plain, red-top tube(s). Spin down and separate within 1 hour of collection and send 3.5 ml