Risk Assessment of NIAS in Food Contact Adhesives
|
|
- Frederica Horn
- 5 years ago
- Views:
Transcription
1 Dr. Monika Tönnießen and Dr. Matthias Frischmann September 2017 Risk Assessment of IAS in Food ontact Adhesives Globally relevant content
2 2/8 Risk Assessment of IAS in Food ontact Adhesives What are IAS? IAS is the abbreviation for non-intentionally added substances. This term was first mentioned in the Plastics Regulation, Regulation (EU) o 10/2011. In recitel 18 and 20 of this regulation IAS are defined as impurities, reaction products and degradation products. The General Guidance on Regulation (EU) o 10/2011 distinguishes four different types of IAS: impurities, by-products, decomposition products and reaction products. There is no food contact material without IAS. All ingredients of a food contact material might be transferred into foodstuffs, which includes the IAS with a low molecular weight below 1000 Da. G/MS screening of a migration solution can help to detect migrated IAS, though it is quite difficult to identify and quantify these substances. Therefore, sharing and exchanging information in the supply chain is a key factor to assess IAS.
3 3/8 Risk Assessment of IAS in Food ontact Adhesives IAS Along the Value hain At each stage of the value chain IAS might be introduced into a food contact material. A strong communication in this chain is essential to identify these substances and to be able to carry out a proper risk assessment. Examples for possible IAS in different types of adhesives are: // By-products as IAS Polyurethane adhesives are often polyester-based. The polyesters are formed by the reaction of diols with diacids. During the production not only polymeric esters are formed but also cyclic esters as unintended by-products. These small molecules easily migrate and have to be risk assessed as IAS. Many water-based adhesives contain a polyvinyl acetate dispersion. It is well-known that during the polymerization of polyvinyl acetate the substances formaldehyde, acetaldehyde, methyl acetate and acetic acid are formed. Also these by-products need to be considered as IAS. Polyvinyl alcohol is an often-used raw material in water-based adhesives. This polymer always contains a technically unavoidable amount of methanol, methyl acetate and sodium acetate as IAS. Figure 1 Polymer Intended main reaction By-products as IAS Unintended side reaction Diols Diacids Long chain polyester yclic esters // Decomposition products as IAS All hotmelt adhesives need stabilizers (antioxidants) to protect the polymer against oxidative degradation. Very often phosphites are used as antioxidants. During storage and in case of thermal stress the phosphite stabilizers in the products are oxidized and afterwards hydrolyzed and form decomposition products. TPP (trisnonylphenyl phosphite) is a well-known stabilizer used for PE material. TPP is listed in the Plastics Regulation (FM 69) and evaluated on European level. After its decomposition this antioxidant releases nonylphenol which is considered as hazardous substance with an endocrine effect. Figure 2 Stabilizer Decomposition product as IAS P xidation Hydrolysis H TPP (AS no ) onylphenol (AS no )
4 4/8 Risk Assessment of IAS in Food ontact Adhesives // Impurities as IAS The raw materials used for adhesives might contain impurities: Polyurethane adhesives are often based on aromatic isocyanates such as 4,4 -MDI and 2,4-TDI. Both monomers contain isomers (2,4 -MDI, 2,2 -MDI respectively 2,6-TDI) as technically unavoidable IAS. The polyurethane laminating adhesives are often based on solvents like ethyl acetate. It is well-known by literature that ethyl acetate contains ethanol, acetaldehyde and acetic acid as impurities due to its production process. Hotmelt adhesives are often polyolefin-based products. Flexible food packaging materials might contain PE or PP films. These polymers always contain a certain amount of low molecular weight oligomers, the so-called PSH (polyolefin oligomeric saturated hydrocarbons) which are IAS and need to be considered as migrateable substances. Figure 3 Monomers H 2 4,4 -MDI 2,4-TDI Isomers as IAS H 2 H 2 2,4 -MDI 2,2 -MDI 2,6-TDI // Reaction products as IAS Aromatic isocyanates are hydrolyzed easily during the application and curing process of polyurethane adhesives at the stage of the converter. These substances create primary aromatic amines (PAA) which are hazardous and considered as carcinogenic, e.g. MDI reacts to MDA as IAS. Figure 4 Monomer Reaction product as IAS H 2 H 2 Methylene diphenyl diisocyanate (MDI) Methylene diphenyl diamine (MDA)
5 5/8 Risk Assessment of IAS in Food ontact Adhesives How are IAS Defined in Analytical Assessments? The screening of migration solutions via G/MS (gas chromatography mass spectrometry) is a well-established and commonly accepted way to gain insight to unexpected and non-intentionally added substances. This technique offers characteristic mass spectra based on mass fragmentations, which help to identify those compounds clearly, either via manual interpretation of the fragmentation patterns or via comparison with comprehensive spectral libraries. For example, a wide range of above mentioned cyclic esters as well as stabilizerderived decomposition products can effectively be monitored using G/MS. Some compounds however cannot be analyzed via gas chromatography, as they are not volatile enough, or might decompose in the course of analysis due to thermal impact. In those cases, other analytical techniques should be considered, based on the chemical composition of the food contact material and the knowledge of typically expected IAS to be expected when using this chemistry. For example, primary aromatic amines (PAA) derived from polyurethane-based adhesives are typically not covered by a general G/MS screening and should be assessed by a targeted, specific test method like e.g. HPL-UV (high performance liquid chromatography UV detection) or L/MS (liquid chromatography mass spectrometry). It is self-evident that the wide range of expected and unexpected IAS needs strong communication along the supply chain to allow for an efficient analytical assessment. Figure 5 Monitoring using G/MS Gas chromatograph with attached mass spectrometer (G/MS) Gas chromatogram Extracted mass spectra Injection needle Detector arrier gas Splitter Injection port G column Unknown 1 = Substance A m/z Identification via spectral database and / or manual interpretation Time Unknown 2 = Substance B m/z
6 6/8 Risk Assessment of IAS in Food ontact Adhesives How are IAS Risk Assessed and ommunicated? IAS are not intended to be included into the Union list of the Plastics Regulation. evertheless, some of the above mentioned IAS are listed because their use as monomers or additives for plastic materials is permitted. According to the General Guidance on Regulation (EU) o 10/2011 IAS have to comply with the general safety requirements of article 3 of the Framework Regulation and are subject to risk assessment in line with article 19 of the Plastics Regulation. Article 3 of the Framework Regulation (E) o 1935/2004 requires that materials and articles coming into contact with food shall be manufactured in such a way that they do not transfer substances into foodstuff in an amount which might endanger human health, cause an unacceptable change in the composition of the food or change the organoleptic characteristics of the food. Article 19 of the Plastics Regulation demands to assess unlisted substances, i.e. substances not yet included in the Union list, in accordance with internationally recognized scientific principles on risk assessment. In consequence, this means that for IAS the same rules have to be applied as for IAS (intentionally added substances). Henkel s evaluation of IAS starts with the food contact raw materials. In our food contact raw material questionnaire we ask our suppliers to list all possible impurities of the raw materials, by-products such as oligomers, decomposition products and reaction products. We also require information about the quantity of these substances in order to be able to carry out a risk assessment based on a worst case calculation. We additionally ask our suppliers if they are aware of possible IAS which might have been developed during the processing or application of the raw material under certain conditions or in contact with certain foodstuffs. After collecting all supplier information and identifying IAS by analytical assessments, we are finally able to create detailed food contact statements. These inform our customers about possible IAS in our raw materials, IAS produced on our stage of the supply chain, i.e. during our production, as well as about IAS our customers might create on their stage of the value chain (e.g. the development of PAAs as a result of an incomplete curing process or PAAs released from a fully cured polyurethane adhesive by hydrolytic decomposition under retort conditions). The IAS chapter represents an important part in our food contact statements. It allows our customers to identify unexpected substances that might possibly migrate. Thus, these will not remain unknown substances causing an uncontrollable issue but become known substances which can be risk assessed for the final product. Due to technical and scientific progress as well as changing customer demands in application, the risk assessment of IAS is not a singular event, but requires constant surveillance and revision of associated documentation.
7 7/8 Risk Assessment of IAS in Food ontact Adhesives Key Take Aways IAS are non-intentionally added substances, either impurities, by-products, decomposition products or reaction products. IAS might occur on each stage of the value chain. They have to be identified and quantified by analytical assessment. IAS have to be risk assessed in the same way as intentionally added substances. Either they are evaluated on European level, e.g. they are listed in the Union list of the Plastic Regulation, or they have to be assessed according to the requirements of article 3 of the Framework Regulation applying internationally recognized scientific principles. A strong communication throughout the whole value chain is the key factor to allow each member of the supply chain to identify IAS and to manage their risks. Literature and useful links Framework Regulation (E) o 1935/ Plastics Regulation (EU) o 10/ Union Guidelines on Regulation (EU) o 10/2011 on plastic materials and articles intended to come into contact with food
8 8/8 Risk Assessment of IAS in Food ontact Adhesives Meet Your Experts Dr. Monika Tönnießen is a chemist by profession and works in the Product Safety Department of the Henkel Adhesive Technologies division. Since 2006 she deals with customer inquiries and is an expert on all food contact related questions. She is a member of the paper & packaging group of the European Adhesive Association FEIA. Dr. Matthias Frischmann is a food chemist by profession and works in orporate Analytics. He is responsible for the Instrumental Analysis Group and a study director according to GLP and GMP guidelines. Since 2008 he is responsible for migration testing and the evaluation of food contact materials with special focus on adhesives and coatings. Further information Visit the Food Safe Packaging Premium Area offering webinars, white papers, FAQs, videos and more: ontact us! Many options available. Webinars ur webinars allow you to directly communicate with our Henkel food safety experts. heck our website for the dates of upcoming webinars. Henkel AG & o. KGaA Düsseldorf, Germany The information provided herein, especially recommendations for the usage and the application of our products, is based upon our knowledge and experience. Due to different materials used as well as to varying working conditions beyond our control we strictly recommend to carry out intensive trials to test the suitability of our products with regard to the required processes and applications. We do not accept any liability with regard to the above information or with regard to any verbal recommendation, except for cases where we are liable of gross negligence or false intention. The information is protected by copyright. In particular, any reproductions, adaptations, translations, storage and processing in other media, including storage or processing by electronic means, enjoy copyright protection. Any exploitation in whole or in part thereof shall require the prior written consent of Henkel AG & o. KGaA. Except as otherwise noted, all marks used in this document are trademarks and/or registered trademarks of Henkel and/or its affiliates in the US, Germany, and elsewhere. Henkel AG & o. KGaA, 9/2017
Dr. Joerg Feesche November 2016 How to Determine Safety of a Food Contact Adhesive
Europespecific content Dr. Joerg Feesche November 2016 How to Determine Safety of a Food Contact Adhesive 2/5 How to Determine Safety of a Food Contact Adhesive Analysis of not Listed Substances One important
More informationGlobally relevant content. Dr. Monika Tönnießen June 2016 Mineral Oil Components in Food Packaging Adhesives
Globally relevant content Dr. Monika Tönnießen June 2016 Mineral Oil Components in Food Packaging Adhesives 02/11 Mineral Oil Components in Food Packaging Adhesives What is mineral oil? The term mineral
More informationDr. Monika Tönnießen, Hartmut Büsching I October 2016 Plasticizers in Food Contact Materials and Adhesives
Dr. Monika Tönnießen, Hartmut Büsching I ctober 2016 lasticizers in Food Contact Materials and Adhesives Europespecific content 02/11 lasticizers in Food Contact Materials and Adhesives Why are plasticizers
More informationComprehensive analysis of the total migrate from can coatings: Solvents vs. simulants vs. foods
Comprehensive analysis of the total migrate from can coatings: Solvents vs. simulants vs. foods What can migrate from FCMs? Known ingredients such as monomers, catalysts, solvents, suspension media, additives,
More informationOfficial Journal of the European Union REGULATIONS
L 30/2 6.2.2015 REGULATIONS COMMISSION REGULATION (EU) 2015/174 of 5 February 2015 amending and correcting Regulation (EU) No 10/2011 on plastic materials and articles intended to come into contact with
More informationUV/EB-curing printing inks
Polymeric Photoinitiators: UV Inks and Coatings for Food Packaging Technical Paper By Roger Küng UV/EB-curing printing inks and coatings are widely used in a variety of packaging applications. When it
More informationHow end-consumer concerns drive raw material innovation in food packaging
How end-consumer concerns drive raw material innovation in food packaging Michaela Hofbauer* 1, Lionel Spack 3 * 1 Eastman Chemical Company, Global Market Leader 3 Nestlé Europe, Senior Packaging Expert
More informationMineral oil hydrocarbons in food: adhesives for food packaging as a source
FEICA FACTSHEET Brussels, 08/09/2014 Mineral oil hydrocarbons in food: adhesives for food packaging as a source Executive Summary In 2011, health concerns were raised after studies were published indicating
More informationRISK ASSESSMENT OF PRIMARY PACKAGING MATERIALS FOR FOOD AND BEVERAGES WITH SPECIAL REFERENCE TO PLASTICS
RISK ASSESSMENT OF PRIMARY PACKAGING MATERIALS FOR FOOD AND BEVERAGES WITH SPECIAL REFERENCE TO PLASTICS Dr. S N Sabapathi Defence Food Research Laboratory Mysore 570 011 Food Contact Materials / Substances
More informationApproach for safety assessment of glass fibre-sizing agents in glass fibre-reinforced plastics for food contact
SCIENTIFIC OPINION ADOPTED: 23 June 2015 PUBLISHED: 14 July 2015 doi:10.2903/j.efsa.2015.4168 Approach for safety assessment of glass fibre-sizing agents in glass fibre-reinforced plastics for food contact
More informationSafe Adhesives for Food Packaging: Risk Assessment Toolbox
Safe Adhesives for Food Packaging: Risk Assessment Toolbox Packaged Summit 19 June 2107 Amsterdam Alexandra Roß Product Regulatory Specialist EIMEA 2 Agenda H.B. Fuller at a Glance Packaging and Packaging
More informationApproaches for the determination of NIAS as a part of Safety-By-Design
Approaches for the determination of NIAS as a part of Safety-By-Design M. Driffield 1, M. Garcia-Lopez 1, E.L. Bradley 1, P.T.K. Oldring 2 1 Fera Science Ltd, 2 Valspar Corp. malcolm.driffield@fera.co.uk
More informationPolyurethane Basic Products
Polyurethane Basic s Isocyanates and polyols for versatile polymers RZ_CMBroschuere_Iso_Poly_Update_0705015.indd Committed to the customer At BASF, our focus is on understanding and meeting our customers
More informationHybrid Coating Technologies Newsletter
Hybrid Coating Technologies Newsletter 2nd Qtr 2017 Issue No. 1 Photos below of the team at HCT and our recent attendance at the highly productive European Coatings Show. Letter from the CEO "Due to the
More informationNOVEL ADHESIVES AND COATINGS FOR FOOD PACKAGING WITH LOW EXTRACTABLES
NOVEL ADHESIVES AND COATINGS FOR FOOD PACKAGING WITH LOW EXTRACTABLES EARL MELBY, PATRICIA HARMAN, JENNY WEAVER, RICK WILLIAMS >>DYNA-TECH ADHESIVES & COATINGS ABSTRACT Coatings made using monomer free
More informationREGULATORY INFORMATION SHEET extrudr PLA NX2
1. Product identification 1.1 Product identifier Trade name Extrudr PLA NX2 1.2 Manufacturer Adress Email FD3D GmbH/Extrudr Höchsterstraße 81 A-6972 Fußach info@extrudr.eu 2. European Union Food Contact
More informationPreventing contamination from food packaging and other food contact materials
Preventing contamination from food packaging and other food contact materials Teagasc Food Packaging seminar for SMEs 29 November 2012 Dr Bernard Hegarty bhegarty@fsai.ie Overview Contamination - How packaging
More informationProbing for Packaging Migrants in a Pharmaceutical Impurities Assay Using UHPLC with UV and Mass Detection INTRODUCTION
Probing for Packaging Migrants in a Pharmaceutical Impurities Assay Using UHPLC with UV and Mass Detection Michael Jones Waters Corporation, Wilmslow, UK APPLICATION BENEFITS The ACQUITY Arc System is
More informationFood Packaging Forum Workshop 5 October 2017 Zürich, Switzerland
Food Packaging Forum Workshop 5 October 2017 Zürich, Switzerland Packaging Safety Challenges Supply Chain Communication Jim Huang Director, Food Contact Materials Global Scientific & Regulatory Affairs
More informationPACKAGING MIGRATION AND HARMFUL ELEMENT COMPLIANCES. By : Mr. Dilip Singh National Manager SGS India Pvt. Ltd.
PACKAGING MIGRATION AND HARMFUL ELEMENT COMPLIANCES By : Mr. Dilip Singh National Manager SGS India Pvt. Ltd. CONCEPT OF MIGRATION TESTING How do you know if the food packaging you wrap your Food in is
More informationChromatography Vacuum Ultraviolet Spectroscopy
Application Note Differentiation and Determination Differentiation and Determination of Fatty Acid Methyl of Fatty Esters Acid by Gas Methyl Chromatography Esters by Vacuum Gas Ultraviolet Spectroscopy
More informationFOOD SAFETY LEGISLATION INDUSTRY LEAFLET
FOOD SAFETY LEGISLATION INDUSTRY LEAFLET 1 AUTHOR Dr. Sara Limbo University of Milan, Italy EDITORS Dr. Johanna Lahti (WG2 Leader) Tampere University of Technology, Finland Sanne Tiekstra, Msc. (Chair
More informationOpinion of the Scientific Committee on Food on the 14th additional list of monomers and additives for food contact materials
EUROPEAN COMMISSION HEALTH & CONSUMER PROTECTION DIRECTORATE-GENERAL Directorate C - Scientific Opinions C2 - Management of scientific committees; scientific co-operation and networks SCIENTIFIC COMMITTEE
More informationNavigating the Regulatory Environment for Food Contact Applications in the USA. PMA 2014 Annual Meeting
Navigating the Regulatory Environment for Food Contact Applications in the USA 1 Introduction to FDA and Food Contact Any food additive should be deemed unsafe unless it is used in conformity with a regulation
More informationDIGLYCEROL. Solvay Interox. Diglycerol General Overview. Product Data Sheet
Product Data Sheet DIGLYCEROL Diglycerol General Overview Polyglycerols have been known since the beginning of the 20th century, and polyglycerol fatty acid esters have been used in Europe and America
More informationThere are no supported uses of VAM in direct consumer products or applications.
Global Product Strategy (GPS) Safety Summary Vinyl Acetate Monomer This GPS Safety Summary is a high-level summary intended to provide the general public with an overview of product safety information
More informationCOMMISSION REGULATION (EU) / of XXX
EUROPEAN COMMISSION Brussels, XXX SANTE/10747/2018 CIS (POOL/E2/2018/10747/10747-EN.doc) [ ](2018) XXX draft COMMISSION REGULATION (EU) / of XXX amending and correcting Regulation (EU) No 10/2011 on plastic
More informationBio-based Building Blocks - Priplast. Taipei, 24 th May 2017
Bio-based Building Blocks - Priplast Taipei, 24 th May 2017 Bio-based Building Blocks Company introduction Raw materials Technology Features & benefits Conclusion Our History Where We Operate Our Technologies
More informationFOOD CONTACT COMPLIANCE DECLARATION
The food contact products listed below are manufactured by Coveris Rigid UK LTD - under the following certified Management Systems in accordance with BRC/IoP 2023/2006/EC (GMP) Document Reference RPET
More informationDECLARATION OF COMPLIANCE
DECLARATION OF COMPLIANCE This document is a Document of Compliance within the meaning of Article 16(1) of Regulation (EC) No. 1935/200 on materials and articles intended to come in contact with food.
More information(Text with EEA relevance) (OJ L 141, , p. 3)
02009L0032 EN 09.11.2016 002.001 1 This text is meant purely as a documentation tool and has no legal effect. The Union's institutions do not assume any liability for its contents. The authentic versions
More informationBEPD butyl ethyl propane diol your glycol of choice for high performance polyester resins. Henrik Bernquist product manager Perstorp AB ECS 2013
BEPD butyl ethyl propane diol your glycol of choice for high performance polyester resins Henrik Bernquist product manager Perstorp AB ECS 2013 BEPD your glycol of choice for high performance polyester
More informationAnalysis of the Non-Ionic Surfactant Triton-X Using UltraPerformance Convergence Chromatography (UPC 2 ) with MS and UV Detection
Analysis of the Non-Ionic Surfactant Triton-X Using UltraPerformance Convergence Chromatography (UPC 2 ) with MS and UV Detection Jane Cooper, 1 Baiba Cabovska 2 1 Waters Corporation, Wilmslow, UK 2 Waters
More informationScientific Challenges in the Risk Assessment of Food Contact Materials 2017 Workshop of the Food Packaging Forum Foundation
Scientific Challenges in the Risk Assessment of Food Contact Materials 2017 Workshop of the Food Packaging Forum Foundation Zürich, October 5, 2017 www.foodpackagingforum.org Welcome FPF s mandate Donations
More informationImpact of FCN772 for Future Food Packaging Applications with UV/EB Technology & The Real-Life Converting Practice
Impact of FCN772 for Future Food Packaging Applications with UV/EB Technology & The Real-Life Converting Practice Presented by: Dr. Albert Lin Henkel Corporation Radtech Conference Chicago, May 5, 2008
More informationIntroduction to Adhesives
Introduction to Adhesives UPACO Division of Worthen Industries Barbara Strickland April 11, 2013 20,000 BC Cavemen Beeswax, Pine Sap feathers on arrows 1500 BC Egyptians Animal glues repair Asphalt mosaics
More informationSCIENTIFIC OPINION. EFSA Panel on food contact materials, enzymes, flavourings and processing aids (CEF) 2,3
SCIENTIFIC OPINION Scientific Opinion on the safety evaluation of the substance, cyclic oligomers of (butylene terephthalate), CAS No. 263244-54-8, for use in food contact materials 1 EFSA Panel on food
More informationBest Practices for OINDP Pharmaceutical Development Programs Leachables and Extractables. II. OINDP Container Closure Systems
Best Practices for OINDP Pharmaceutical Development Programs Leachables and Extractables II. OINDP Container Closure Systems PQRI Leachables & Extractables Working Group PQRI Training Course April 12-13,
More informationMEASURING GRINDING PERFORMANCE IN UV RESIN SYSTEMS FOR PIGMENT PASTES AND CONCENTRATES
MEASURING GRINDING PERFORMANCE IN UV RESIN SYSTEMS FOR PIGMENT PASTES AND CONCENTRATES Paulo Roberto Vieira Junior, Marc Heylen, Paul Gevaert, Francis Bergiers, Luc DeWaele, Rosalyn Waldo, and Peter Yuan.
More informationReactive polymer-bound stabilizers for polyols and PU, improving emissions and long term yellowing of foam
Reactive polymer-bound stabilizers for polyols and PU, improving emissions and long term yellowing of foam Antoni Puig Sales Manager EMEA PSE Europe, 28 th June 2017, Munich Milliken & Company Headquartered
More informationL 113/18 EN Official Journal of the European Union COMMISSION REGULATION (EU) 2017/752 of 28 April 2017 amending and correcting Regulation (
L 113/18 EN 29.4.2017 COMMISSION REGULATION (EU) 2017/752 of 28 April 2017 amending and correcting Regulation (EU) No 10/2011 on plastic materials and articles intended to come into contact with food (Text
More informationProduct Safety Summary for MDI, Polymeric MDI, and MDI-based Products
Product Safety Summary for MDI, Polymeric MDI, and MDI-based Products This Product Safety Summary is intended to provide a general description of certain Bayer MaterialScience (BMS) chemical products and
More informationRegulatory Data Sheet of LUCENE Polyolefin Elastomers LUCENE POE LF100 (Ethylene-1-OCtene-Copolymer)
Regulatory Data Sheet of LUCENE Polyolefin Elastomers LUCENE POE LF100 (Ethylene-1-OCtene-Copolymer) 1. United States Food and Drug Administration This product complies with the US FDA Regulation 21 CFR
More informationCOMMISSION REGULATION (EU) No /.. of XXX
EUROPEAN COMMISSION Brussels, XXX [ ](2013) XXX draft COMMISSION REGULATION (EU) No /.. of XXX amending Annex XVII to Regulation (EC) No 1907/2006 of the European Parliament and of the Council on the Registration,
More informationUVACURID C71 Series Low-Migration UV Curing Dry Offset Printing Ink
UVACURID C71 Series Low-Migration UV Curing Dry Offset Printing Ink Characteristics The UVACURID C71-Series is a low-migration ink series of the next generation. It is suitable for printing food packaging
More informationPolyester Diols. A comprehensive range of polyester diols that can be customized with flexibility and responsiveness. It s all about the chemistry
Polyester Diols A comprehensive range of polyester diols that can be customized with flexibility and responsiveness Formulators can achieve specific properties geared to the final application with our
More informationFatty acid product guide
Fatty acid product guide Kraton Corporation s Sylfat and Century fatty acids are useful in a wide range of industrial applications. These fatty acids (tall oil fatty acid, monomer acid, stearic acid and
More informationHPHP- A Component for Enviornmentally Advanced Coatings
HPHP- A Component for Enviornmentally Advanced Coatings m 2 fd- Don Morris Texas Eastman Division, P.O. Box 7444 Longview, Texas 75607 The coating s industry is undergoing a dramatic shift from solvent
More informationThis document is meant purely as documentation tool and the institutions do not assume any liability for its contents
1978L0142 EN 01.02.1978 000.001 1 This document is meant purely as documentation tool and the institutions do not assume any liability for its contents "B COUNCIL DIRECTIVE of 30 January 1978 on the approximation
More informationCOMMISSION REGULATION (EU)
11.3.2011 Official Journal of the European Union L 64/15 COMMISSION REGULATION (EU) No 234/2011 of 10 March 2011 implementing Regulation (EC) No 1331/2008 of the European Parliament and of the Council
More informationUsing Software Tools to Improve the Detection of Impurities by LC/MS. Application Note. Christine Miller Agilent Technologies.
Using Software Tools to Improve the Detection of Impurities Application Note Christine Miller Introduction The analysis of raw materials and finished products for or impurities presents a challenge in
More informationDRAFT MONOGRAPH FOR THE INTERNATIONAL PHARMACOPOEIA PAEDIATRIC RETINOL ORAL SOLUTION (August 2010)
August 2010 RESTRICTED DRAFT MONOGRAPH FOR THE INTERNATIONAL PHARMACOPOEIA PAEDIATRIC RETINOL ORAL SOLUTION (August 2010) DRAFT FOR COMMENT This document was provided by a quality control expert and was
More informationCYCLOSERINI CAPSULAE - CYCLOSERINE CAPSULES (AUGUST 2015)
August 2015 Document for comment 1 2 3 4 5 CYCLOSERINI CAPSULAE - CYCLOSERINE CAPSULES DRAFT PROPOSAL FOR THE INTERNATIONAL PHARMACOPOEIA (AUGUST 2015) DRAFT FOR COMMENT 6 Should you have any comments
More informationAS Application Note 1602
Determination of the fatty acid composition in refined oils and fats by alkaline transesterification by the ASAN 1602 Status: February 2018 Page 1 / 12 Introduction Animal and vegetable fats play a key
More informationa 1 st list of substances for food contact materials
, 1-9 Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food (AFC) on a request from the Commission related to a 1 st list of substances for
More informationOpinion of the Scientific Committee on Food on an additional list of monomers and additives for food contact materials (adopted the 18 September 1998)
Opinion of the Scientific Committee on Food on an additional list of monomers and additives for food contact materials (adopted the 18 September 1998) The Committee (re)evaluated a number of monomers and
More informationUltra High Performance Liquid Chromatograph. Nexera X2 C196-E079
Ultra High Performance Liquid Chromatograph Nexera X2 C196-E79 Maximizing the Potential of UHPLC/HPLC Analyses Intelligence Intelligent data solutions, including a new i -PDeA peak calculation method for
More informationVersatic. Acids and Derivatives. Product Overview
Versatic Acids and Derivatives Product verview Hexion is the number one global supplier of Versatic acids and derivatives, primarily to the polymer, paints, coatings, construction and adhesives markets.
More informationSmall Scale Preparative Isolation of Corticosteroid Degradation Products Using Mass-Based Fraction Collection Application
Small Scale Preparative Isolation of Corticosteroid Degradation Products Using Mass-Based Fraction Collection Application Pharmaceutical Author Cliff Woodward Agilent Technologies, Inc. 285 Centerville
More informationTECHNICAL UPDATE. Introducing SMA EP400 Resin and EP400S Resin Solution for Improved Copper Adhesion in Copper Clad Laminate BENEFITS.
BENEFITS Excellent reactivity Improved adhesion to copper Non-tacky prepregs Multi-functional, effective crosslinker High chemical resistance TARGET MARKETS Copper Clad Laminates Structural Composites
More informationFDA Food Contact Fundamentals
FDA Food Contact Fundamentals Deborah Attwood 2017 SPE International Polyolefins Conference March 1, 2017 Legal Highlights for Food 1906: Pure Food and Drug Act 1938: Federal Food, Drug and Cosmetic Act
More informationFDA s Food Additives Program
FDA s Food Additives Program LaShonda T. Cureton, PhD Office of Food Additive Safety US Food and Drug Administration Food Additives: A Global Perspective on Safety Evaluation and Use Procedures for Approval
More informationWATERBASED RADIATION-CURABLE POLYURETHANE ACRYLATE COATINGS
WATERBASED RADIATI-CURABLE PLYURETAE ACRYLATE CATIGS by Y. eischkel*, K. Menzel+, E. Beck+, K.. Sass&, C. A. Glotfelter, F. Masson#, C. Decker#, and R. Schwalm*, BASF AG, *Polymer Research Laboratory,
More informationQ2. What categories of production aids can be used in manufacturing paper pulp?
Q&A of the 4 th Food Contact Material Safety Forum With the publication of new Chinese FCM national safety regulations, the focus of this forum is to discuss the possible impacts on both the surveillance
More informationBio-based Solutions for High-Performance Polyurethane Adhesives. Angela Smits Bio-based Adhesives Conference 2013
Bio-based Solutions for High-Performance Polyurethane Adhesives Angela Smits Bio-based Adhesives Conference 213 Bio-based building blocks sustainable solutions CRODA: Naturally derived speciality chemicals
More informationDelegations will find attached document D044711/03 - Annex 1.
Council of the European Union Brussels, 12 May 2016 (OR. en) 8801/16 ADD 1 DENLEG 44 AGRI 255 SAN 179 COVER NOTE From: European Commission date of receipt: 10 May 2016 To: General Secretariat of the Council
More informationINTERNATIONAL PHARMACOPOEIA MONOGRAPH ON LAMIVUDINE TABLETS
RESTRICTED INTERNATIONAL PHARMACOPOEIA MONOGRAPH ON LAMIVUDINE TABLETS DRAFT FOR COMMENT Please address any comments you may have on this document, by 12 July 2006, to Dr S. Kopp, Quality Assurance and
More informationChemicals Based on Ethylene
Chemicals Based on Ethylene Ethylene is sometimes known as the king of petrochemicals because more commercial chemicals are produced from ethylene than from any other intermediate. This unique position
More informationThe Chemicals Migration Research Of Plastic Food Packaging
2017 3rd International Conference on Environment, Biology, Medicine and Computer Applications(ICEBMCA 2017) The Chemicals Migration Research Of Plastic Food Packaging Yang Wang1, Biao Zhang1, * 1 Quality
More informationAlkyd-derived Urethane Acrylate Oligomers in UV Curable Coatings; Synthesis and Properties
Alkyd-derived Urethane Acrylate ligomers in UV Curable Coatings; Synthesis and Properties A.J. Tortorello DSM Desotech, Inc. 1122 St. Charles Street Elgin, IL 60120 USA Introduction Urethane acrylates
More informationEuropean Union legislation on Food additives, Food enzymes, Extractions solvents and Food flavourings
European Union legislation on Food additives, Food enzymes, Extractions solvents and Food flavourings European Commission, DG, Unit E3 Chemicals, contaminants and pesticides Serbia-Screening meeting on
More informationUV/EB Chemistry to Improve Package Durability. James E. Goodrich
UV/EB Chemistry to Improve Package Durability James E. Goodrich May 24, 2010 Introduction UV/EB chemistry has many environmental and processing advantages that are useful Still more advantages being researched
More informationOPINION ON AN ADDITIONAL LIST OF MONOMERS AND ADDITIVES FOR FOOD CONTACT MATERIALS
EUROPEAN COMMISSION HEALTH & CONSUMER PROTECTION DIRECTORATE-GENERAL Directorate B - Scientific Health Opinions Unit B3 - Management of scientific committees II SCIENTIFIC COMMITTEE ON FOOD SCF/CS/PM/(GEN)/M80
More informationPOSITION PAPER. Monomers - Proposed requirements for Appendix C of the Toy Safety Directive
POSITION PAPER Monomers - Proposed requirements for Appendix C of the Toy Safety Directive 7 MAY 2018 Contact Person: Tania Vandenberghe, Senior Programme Manager (tania.vandenberghe@anec.eu) Raising standards
More informationQuantification of isocyanates and amines in polyurethane foams and coated products by liquid chromatography tandem mass spectrometry
ORIGINAL RESEARCH Quantification of isocyanates and amines in polyurethane foams and coated products by liquid chromatography tandem mass spectrometry Motoh Mutsuga, Miku Yamaguchi & Yoko Kawamura National
More informationMATERIAL SAFETY DATA SHEET
SECTION 1 - PRODUCT AND COMPANY IDENTIFICATION Product Name: Plastics Bonding UV Visible Light Adhesive Item Numbers MATERIAL SAFETY DATA SHEET Extreme 3106 UV curing Adhesive Product Use/Class: Extreme
More informationCarnitine / Acylcarnitines Dried Blood Spots LC-MS/MS Analysis Kit User Manual
Page 1 / 14 Carnitine / Acylcarnitines Dried Blood Spots LC-MS/MS Analysis Kit User Manual ZV-3051-0200-15 200 Page 2 / 14 Table of Contents 1. INTENDED USE... 3 2. SUMMARY AND EXPLANATION... 3 3. TEST
More informationThe Italian approach to the safety assessment of coatings intended for food contact application
The Italian approach to the safety assessment of coatings intended for food contact application Riccardo CREBELLI, Maria Rosaria MILANA Istituto Superiore di Sanità Roma ( ITALY) FIP Network - EFSA ( TC)
More informationPOLIMERSAN A.S. Orta Mahalle Universite Cd. 29 Orhanli-Tuzla Istanbul (EE)
FOOD PACKAGING MATERIALS FOOD CONTACTS 04\FPM\FDC\14_3 Rev. 1 1/05/2014 1 POLIMERSAN A.S. Orta Mahalle Universite Cd. 2 Orhanli-Tuzla 3456 Istanbul (EE) D.P.R. 777 dated 23/08/182, D.L. 108 dated 25/01/12,
More informationCORROSION INHIBITORS CATALOGUE
CORROSION INHIBITORS CATALOGUE PETROSTEP CORROSION INHIBITORS: PROTECT AND PRESERVE Corrosive agents can be found throughout the oilfield, from pipelines to production and injection wells, to storage
More informationKey Words: Brassica oleraceae, glucosinolate, liquid chromatography mass spectrometry, FNH-I-003
IDENTIFICATION OF MAJOR GLUCOSINOLATES IN BROCCOLI (Brassica oleracea var. italica) BY LIQUID CHROMATOGRAPHY MASS SPECTROMETRY (LC-MS) AND DETERMINATION OF ANTICANCER PROPERTIES OF BROCCOLI EXTRACTS Carlos
More informationProduct Safety Assessment Toluenediamine Propoxylated/Ethoxylated Polyols
Product Safety Assessment Toluenediamine Propoxylated/Ethoxylated Polyols Product Safety Assessment documents are available at: www.dow.com/productsafety/finder/. Select a Topic: Names Product Overview
More informationMATERIAL SAFETY DATA SHEET
Page 1 of 5 SECTION I: PRODUCT INFORMATION PRODUCT: Sikaflex -221 US (MSDS N o 604251) REVISION DATE: April 18 th, 2016 USAGE: SUPPLIER: ONE COMPONENT URETHANE BASED ADHESIVE / SEALANT SIKA CANADA INC.
More informationScientific Opinion on the safety evaluation of the process INTERSEROH Step 1 used to recycle polypropylene crates for use as food contact material 1
ABSTRACT SCIENTIFIC OPINION Scientific Opinion on the safety evaluation of the process INTERSEROH Step 1 used to recycle polypropylene crates for use as food contact material 1 EFSA Panel on Food Contact
More informationScientific Opinion on the safety evaluation of the substance bis(2,6-diisopropylphenyl)carbodiimide for use in food contact materials 1
SCIENTIFIC OPINION Scientific Opinion on the safety evaluation of the substance bis(2,6-diisopropylphenyl)carbodiimide for use in food contact materials 1 EFSA Panel on food contact materials, enzymes,
More informationMOSH/MOAH QUESTIONS AND ANSWERS
MOSH/MOAH QUESTIONS AND ANSWERS WHAT IS MOSH/MOAH? MOSH/MOAH is the umbrella term describing mineral oil hydrocarbons that can migrate from packaging materials into foodstuffs during transportation and
More informationKUMHO SAN Overview. November, Kumho Petrochemical Research & Business Development Center
KUMHO Overview November, 2016 Kumho Petrochemical Research & Business Development Center Table of Contents I. General Features of KUMHO Resin II. KUMHO Products III. Food Contact Materials Ⅰ. General Features
More informationSunPak FSP. 1. Description SunPak FSP is a series of low migration* sheetfed offset process inks for sensitive (food and tobacco) packaging.
1. Description SunPak FSP is a series of low migration* sheetfed offset process inks for sensitive (food and tobacco) packaging. 2. Product features SunPak FSP inks: allow the production of food packaging
More informationFTR-601A Adhesive, Part A
SAFETY DATA SHEET FiberTite FTR-601A Adhesive, Part A Rev. Date: 23 Dec 2014 SECTION 1. Product Name: PRODUCT & COMPANY INFORMATION FTR-601A Adhesive, Part A Recommended Use: Foamable adhesive Manufacturer:
More informationMATERIAL SAFETY DATA SHEET
Page 1 of 5 SECTION I: PRODUCT INFORMATION REVISION DATE: February 1 st, 2015 USAGE: ONE COMPONENT URETHANE BASED SEALANT / ADHESIVE MANUFACTURER/SUPPLIER: SIKA CANADA INC. 601, avenue Delmar Pointe Claire,
More informationScientific Opinion on the safety evaluation of the substance, 3,4-diacetoxy-1-butene, CAS No , for use in food contact materials 1
SCIENTIFIC OPINION Scientific Opinion on the safety evaluation of the substance, 3,4-diacetoxy-1-butene, CAS No. 18085-02-4, for use in food contact materials 1 EFSA Panel on food contact materials, enzymes,
More informationSCIENTIFIC OPINION. EFSA Panel on food contact materials, enzymes, flavourings and processing aids (CEF) 2, 3
SCIENTIFIC OPINION Scientific Opinion on the safety evaluation of the substance, poly(12-hydroxystearic acid)-polyethyleneimine copolymer, CAS No. 124578-12-7, for use in food contact materials 1 EFSA
More informationProf. Marina Heinonen University of Helsinki Member of the NDA Panel and EFSA s WG on Novel Foods
Guidance on Novel Foods Composition, production process and specification Prof. Marina Heinonen University of Helsinki Member of the NDA Panel and EFSA s WG on Novel Foods Info-Session 06 March 2017 Parma
More informationScientific Opinion on the safety evaluation of the substance glycolic acid for use in food contact materials 1
SCIENTIFIC OPINION Scientific Opinion on the safety evaluation of the substance glycolic acid for use in food contact materials 1 EFSA Panel on food contact materials, enzymes, flavourings and processing
More informationOpinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) on a request related to
The EFSA Journal (2006) 316 to 318, 1-10 Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) on a request related to an 11 th list of
More informationPRODUCT REGULATORY INFORMATION SHEET Print Date: 5/6/2016 Version: 05/06/2016 (00,000.00,000) Eastman Amphora(TM) 3D Polymer HT5300
PRODUCT NAME COMPANY INFORMATION Address Eastman Chemical Company P. O. Box 511 Kingsport, TN 37662 FOOD CONTACT / FOOD ADDITIVE / FEED ADDITIVE INFORMATION Asia Pacific Region China EMEA Region European
More informationAQ 191 A Page 1 of 5 Sika Canada Inc. MATERIAL SAFETY DATA SHEET Date:99/09/30 App S.G.
Page 1 of 5 SECTION I: PRODUCT INFORMATION PRODUCT: SIKAFLEX PRIMER 429/202 REVISION DATE: February 15, 2006 USAGE: MANUFACTURER: SIKA CANADA INC. 601, avenue Delmar Pointe Claire, QC H9R 4A9 EMERGENCY
More informationSCIENTIFIC OPINION. EFSA Panel on food contact materials, enzymes, flavourings and processing aids (CEF) 2, 3
EFSA Journal 2012;10(7):2825 SCIENTIFIC OPINION Scientific Opinion on the safety evaluation of the substance, 2-phenyl-3,3-bis(4-hydroxyphenyl)phthalimidine, CAS No. 6607-41-6, for use in food contact
More informationKEYWAX WX1014 RUBBER WAX CONCENTRATE
PRODUCT DESCRIPTION ADVANTAGES KEYWAX WX1014 RUBBER WAX CONCENTRATE (TYPICAL PROPERTIES) These should not be considered as specifications. KEYWAX WX1014 is a is a blend of 15% polyisobutylene rubber in
More informationSuper Absorbent Polymers (SAPs)
TPP Super Absorbent Polymers (SAPs) A comprehensive range of products that provide comfort and convenience in countless ways SONGWON offers an extensive range of polymers. Solution (thermosetting and/or
More information