Epidemiological situation on rotavirus infection and prospects for vaccination introduction in the Republic of Belarus

Transcription

1 Epidemiological situation on rotavirus infection and prospects for vaccination introduction in the Republic of Belarus I. Karaban, Ministry of Health of the Republic of Belarus I. Glinskaya, Deputy Chief Medical Officer of the State Institution «Republican centre, for hygiene, epidemiology and public health», candidate of medical sciences H. Samoylovich, Head of the vaccine-preventable infections laboratory of the State Institution «Republican research and practical centre for epidemiology and microbiology» doctor of medical sciences, professor

2 MAIN CHARACTERISTICS OF EPIDEMIOLOGICAL SURVEILLANCE FOR ROTAVIRUS INFECTION SYSTEM IN THE REPUBLIC OF BELARUS Epidemiological surveillance system Integrated surveillance Information subsystem Laborotary-based surveillance Лабораторноориентированный надзор Syndromic surveillance Синдромный надзор Diagnostic subsystem Informal surveillance Неформальный надзор Organization of sanitary and antiepidemic activities

3 MAIN CHARACTERISTICS OF EPIDEMIOLOGICAL SURVEILLANCE FOR ROTAVIRUS INFECTION SYSTEM IN THE REPUBLIC OF BELARUS Rotavirus infection sentinel surveillance Clinical bases: infectious hospitals of regional cities and 12 major cities The purpose of conduction: - in-depth evaluation of the epidemiological situation; - monitoring of the circulation of virus genotypes - introduction of measures to prevent the spread of infection Microbiological laboratories of regional and Minsk city centres for hygiene and epidemiology State institution «Republican Research and Practical Centre for Epidemiology and Microbiology»

4 LONG-TERM MORBIDITY DYNAMICS IN THE REPUBLIC OF BELARUS FOR (INDICATOR PER 100 THOUSAND POPULATION) Number of nosological forms широко распространенные инфекции средне распространенные инфекции мало распространенные инфекции редко встречающиеся инфекции

5 ANNUAL MORBIDITY DYNAMICS ACCORDING TO THE AVERAGE LONG-TERM FIGURES FOR (INDICATOR PER 100 THOUSAND POPULATION) Specific weight for year-round morbidity- 35%, Specific weight for seasonal morbidity 65% No incidence of outbreak was recorded June July August 4, ,59 1, September ,644 2,208 2,502 October 3,81 November December 5,21 7,328 May 6,482 January The peak of incidence was in April 9,236 April 8,342 February March average monthly incidence rate on average long-term figures for upper limit of year-round incidence

6 ROTAVIRUSES GENETIC STRUCTURE (MINSK (n=1122) % G3 P[8] 64.7% G4 P[8] % % 16.8% 60.4% 54.9% 42.4% 23.5% 55.4% 69.4% 61.5% 40.8% G9 P[8] 40.0% 0% 20% 40% 60% 80% 100% G1P[8] G2P[4] G3P[8] G4P[8] G9P[8] G2P[6] G2P[8] G3P[9] G4P[6] G8P[4] G9P[4] G12P[6] G12P[8] Смеси Nt

7 AGE-STRUCTURE OF ROTAVIRUS INFECTION MORBIDITY FOR YEARS (IN PERCENTAGES (%) 100,0 90,0 3,5 4,8 0,5 2,8 0,2 2,8 5,8 5,5 4,5 0,4 1,1 1,0 4,0 6,0 5,9 80,0 24,3 23,0 23,1 25,1 25,2 70,0 Adults in per centages (%) 60,0 50,0 40,0 46,2 48,7 46,3 42,9 43,3 Children aged Children aged ,0 Children aged ,0 Children aged ,0 22,7 20,4 20,4 19,3 20,1 Children under the age of 1 0,

8 SOCIAL AND AGE STRUCTURE AND SEVERITY OF ROTAVIRUS INFECTION MORBIDITY, (IN PERCENTAGES(%) 5,2 0,5 4,6 children not attending preschool children attending preschool 6,7 0,65,9 27,1 62,6 schoolchildren college and univ ersity students adults 27,8 59,0 weighted average annual data for specific weight for 6 month of ,6 97 0,4 slight aver age severe

9 IMMUNIZATION PROGRAMME PROSPECTS Haemophilus infection Varicella Pneumococcal infection Meningococcal infection Rotavirus HPV-infection

10 IMMUNIZATION PROGRAMME PROSPECTS Haemophilus infection Introduced in 2018 Varicella Pneumococcal infection Rotavirus Meningococcal infection HPV-infection

11 Expert Council on Immunization of the Ministry of Health of the Republic of Belarus - analogue of the National Technical Advisory Group on Immunization Orders of the Ministry of Health of the Republic of Belarus from May 6, and from April 22, chairman deputy chairman pediatricians, infectious disease doctors, clinical pharmacologist, epidemiologists, microbiologists, virologist, phthisiatrician, obstetrician-gynecologist, specialist in vaccine regulation

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