Assessing quality of life in sarkoma trials
|
|
- Daniela Allen
- 5 years ago
- Views:
Transcription
1 Pan-European Clinical Trials under current EU regulations: A training course for data managers, study nurses, and junior clinical investigators London, January 24/25, 2008 Assessing quality of life in sarkoma trials Gabriele Calaminus, MD QoL working group Dept. of Paediatric Oncology, Haematology, Münster, Germany 1
2 Frequency of sarcoma 8,3 6,6 4,5 11,1 % Sarcomas 12,2 6 3,4 4,5 21,4 33,1 soft tissue sarcomas bone tumours renal tumours Germ cell tumours other diagnosis Leukaemias CNS tumours Lymphomas Sympathetic nervous system tumours * Kaatsch et al. :Annual Report 2005 German Childhood Cancer Registry 2 6
3 Treating children with cancer Survival is the goal 3
4 Development of Survival Rates Years Survival Rates [%] Year of diagnosis Osteosarcoma Ewing s Sarcoma Rhabdomyosarcoma Morbus Hodgkin Wilms Tumor Acute lymphocytic leukemia Non-Hodgkin-Lymphoma Malignant germ-cell tumours Neuroblastoma Brain tumors Acute myelogenous leukemia 4
5 The Erice Statement
6 What is Quality of Life? the individual perspective in respect to aims, expectations, possibilities influenced by cultural environment. it contains but is not limited to social, emotional and physical capacities of the child / adolescent and his family it has to be viewed from the perspective of the child / adolescent and the family and should include developmental changes Bradlyn,
7 Child outward appearance (nice hair) physical activity (to run, climb, play...) friends Adolescent friends, body image, outward appearance, self dependency, professional training Young adult Autonomy (income, to live independent) professional training, job steady partnership 7
8 Factors influencing QoL age range prognostic variability education Health- /social system treatment diversity duration intensity mutilation compliance Psychosocial network patient / family Quality of life 8 2
9 Measuring QoL Why... How Analysis Interpretation Timing Logistics... 9
10 Measuring QoL: Why? 10
11 QoL data provide additional information to compare treatment strategies Additional information to survival data detection of changes in psychosocial functioning value of physical and psychosocial rehabilitation value of palliative care 11
12 Measuring QoL: How? 12
13 Interviews Limitations: data security, staff, time consuming self / proxy report Questionaires Limitations: different view on QoL and problems self reporting 8 years Limitations: age, ability to understand things 13
14 Analysis Evaluation of scores for different domains and correlation to Norm Groups - Age and sex Significant differences (negative/positive) Over time (E1 E2.. E3 same treatment At one time point between treatment arms 14 2
15 Examples 15
16 Quality of Life in schoolchildren n= % Prozente negativ 60 Autonomiy E K p < 0.05 C 40 Body image p < 0.05 FR J J J. FAM 16
17 Longitudinal comparision of QoL data E2 E3 E4 Week 10 ± 2 post surgery Week 72 ± 4 Week 144 ± 4 E2 E3 E4 E1 Week 10 ± 2 post surgery Week 72 ± 4 Week 144 ± 4 Week 5 E2 E3 E4 Week 10 ± 2 post surgery Week 72 ± 4 Week 144 ± 4 E2 E3 E4 Week 10 ± 2 post surgery Week 72 ± 4 Week 144 ± 4 17
18 Cross sectional comparision of QoL data E2 E3 E4 Week 10 ± 2 post surgery Week 72 ± 4 Week 144 ± 4 E2 E3 E4 E1 Week 10 ± 2 post surgery Week 72 ± 4 Week 144 ± 4 Week 5 E2 E3 E4 Week 10 ± 2 post surgery Week 72 ± 4 Week 144 ± 4 E2 E3 E4 Week 10 ± 2 post surgery Week 72 ± 4 Week 144 ± 4 18
19 Interpretation Correlation to Norm Groups Age and sex Correlation to treatment Surgery, chemo, RT Correlation to somatic data toxicity, functional abilities 19 2
20 Timing Intervals between evaluation > 6 weeks Time window not to short Instruments easy assessable Reminder system effective 20 2
21 Logistics 21 2
22 Flow of QoL information / data in Germany E1 / E2 COSS Stuttgart data synchronisation announcement of registration QoL-center Düsseldorf Deutsches Krebsregister Mainz Attending clinic/physician Patient / Parents E1 and E2 obligatory reminder / QoLbooklets were posted to but returned by patient/parents directly 22
23 Sarcoma What do we know about QoL? 23
24 3/16 (20%) of hospitals account for 60% of Ewing and osteosarcoma patients schooling/vocational training is of high importance in terms of successful long-term rehabilitation. This enables accessible employment, security and the ability to build up own family structures No difference for amputees and non-amputees 24 2
25 3/16 (20%) of hospitals account for 60% of Ewing and Osteosarcoma patients At assessment median age was 15 years, Mean scores were 60, 81, 76, 74, 70, 87 for general health, physical functioning, pain, mental health, self- esteem, family activity Lower results were observed for mental health in girls, for physical functioning, and self-esteem in patients with endoprosthesis, for family activity and pain in patients who had relapsed. 25 2
26 3/16 (20%) of hospitals account for 60% of Published studies patients The main impact on Qol has the ability to participate in normal life roles: get and maintain employment have a familiy and care for it participate in recreational activites 26 2
27 Clinical Outcome and QoL? 27
28 Examples 28
29 Craniopharngeoma impact of RT after incomplete resection 29
30 +/- RT do not implicate a difference in QoL in patients with incompletely resected craniopharngeoma > 2 years after the end of treatment % Median SE E KB C K Fam Fr Normgroup, n=550 - RT n=16 + RT n=21 0 (11/04) 30
31 obesity in Craniopharngeoma 2 years after Dx 31
32 Obese Craniopharyngeoma pts rate their QoL more negative than non-obese pts % Median SE E KB C K Fam Fr BMI > 3 SD BMI < 2 SD p <
33 Cross sectional / longitudinal QoL study (prospective, multicenter) Example: COSS/EURAMOS 1 Investigation of Quality of Life (QoL) in young patients with Osteosarkoma (as one secondary end of the trial) Trial opening in Germany 04/
34 COSS/EURAMOS 1 problems of interest 1. How do young patients with Osteosarkoma appraise their QoL? 2. Is there a difference in QoL between good and poor responders? (cross sectional comparison) 3. Does the additional application of interferon-alpha affect the QoL in patients with good prognosis? 4. Is the QoL affected in patients with poor responding and more intensive therapy? 5. Does the QoL change during and after therapy? (longitudinal comparison) 34
35 Further areas of interest Influence of disease age treatment on QoL surgery irradiation 35
36 Quality of Survival! professional rehabilitation functional outcome Risks histo/site therapy late effects Genetics Sarcoma patient Coping subjective well-being Intact social network Access to insurrance and health care 36
37 QoL working group (Münster) Gabriele Calaminus, MD Pediatrist Head QoL working group Andreas Wiener Pediatric Psychologist Study Coordinator Carmen Teske Data Manager Contact address: Dr. G. Calaminus University Children's Hospital Dept. of Paed.Oncology, Haematology University Hospital Albert-Schweitzerstr.33 D Münster Germany phone:
38 Thank you for your interest 38
36 years childhood cancer registration in Germany. A network between clinics, clinical studies and the registry
(GCCR) 36 years childhood cancer registration in Germany A network between clinics, clinical studies and the registry Peter Kaatsch Claudia Spix, Desiree Grabow 40 years Swiss Childhood Scientifc symposium,
More informationA Summary of Childhood Cancer Statistics in Australia,
What is the Australian Paediatric Cancer Registry (APCR)? The APCR is one of only a few national registries of childhood cancer in the world. It covers all Australian children aged 0-14 years old at diagnosis.
More informationSCIENTIFIC TIMETABLE SIOP 2015
SCIENTIFIC TIMETABLE SIOP 2015 September, 2015 WEDNESDAY, 7 TH OCTOBER 2015 / DAY 2 1.43 09:30 SIOP Committee 12:00 SIOP Essential Drugs Working 13:00 SIOP Work (Open) 14:00 Nurse Researchers 16:00 17:00
More informationSIOP. 7 TH ESO-SIOP EUROPE MASTERCLASS IN PaEDiatRic OncOlOGy June 2018 nauen Ot Groß Behnitz (Berlin area), Germany.
SIOP SIOP Europe the European Society for Paediatric Oncology 7 TH ESO-SIOP EUROPE MASTERCLASS IN PaEDiatRic OncOlOGy 16-21 June 2018 nauen Ot Groß Behnitz (Berlin area), Germany Chairs: S. Bielack, DE
More information6 TH ESO-SIOP EUROPE MASTERCLASS IN PAEDIATRIC ONCOLOGY June 2016 Berlin, Germany. Chairs: A. Eggert, DE B. Morland, UK R.
MASTERCLASS 6 TH ESO-SIOP EUROPE MASTERCLASS IN PAEDIATRIC ONCOLOGY Held with the support of 11-16 June 2016 Berlin, Germany Chairs: A. Eggert, DE B. Morland, UK R. Riccardi, IT INTRODUCTION ESO and SIOP-Europe
More informationShared Care & Survival CTYA SSCRG (Childhood Cancer Research Group)
Shared Care & Survival CTYA SSCRG (Childhood Cancer Research Group) January 2013 The NCIN is a UK-wide initiative, working to drive improvements in standards of cancer care and clinical outcomes by improving
More informationASCONA 07/11/08 PAEDIATRIC ONCOLOGY. 2 nd ESO-SIOPE MASTERCLASS IN November 2008 Ascona, Switzerland
MASTERCLASS ASCONA 07/11/08 2 nd ESO-SIOPE MASTERCLASS IN PAEDIATRIC ONCOLOGY 7-13 November 2008 Ascona, Switzerland Chair: R. Riccardi, IT - M.C.G. Stevens, UK - A. Eggert, DE Educational Advisor: W.
More informationCLIC Sargent Eligibility Criteria
1 Eligibility Criteria DOCUMENT GOVERNANCE: Eligibility criteria Produced by J. Hawkins & Grants Team Sponsored by Dara de Burca Version Approval by Executive Team 10 th June 2014 Board of Trustees 3 rd
More informationPEDIATRIC. BRAIN ACNS 0332: Efficacy of Carboplatin Administered Concomitantly with Radiation and Isotretinoin as a COMPANION STUDIES
PEDIATRIC BRAIN ACNS 0332: Efficacy of Carboplatin Administered Concomitantly with Radiation and Isotretinoin as a Pro-Apoptotic Agent in other than Average Risk Medulloblastoma/PNET Patients. https://clinicaltrials.gov/ct2/show/nct00392327?term=0332&rank=6
More informationCancer in Children. Dr Anant Sachdev Cancer Lead Berkshire East, GPSI Palliative Medicine
Cancer in Children Dr Anant Sachdev Cancer Lead Berkshire East, GPSI Palliative Medicine 07976 608871 anant.sachdev@nhs.net Aim of this very short session! Facts and figures relating to Childrens Cancers
More informationChildhood Cancer. Dr Sarah Taaffe. Grace Kelly LadyBird Trust RCGP Child and Young Persons Cancer E-learning Session
Childhood Cancer Dr Sarah Taaffe Grace Kelly LadyBird Trust RCGP Child and Young Persons Cancer E-learning Session What I plan to cover in this session Background- Why this topic.. What types of cancer
More informationProspective Trial for the Diagnosis and Treatment of Intracranial Germ Cell Tumors (SIOPCNSGCTII)
1 von 9 10.12.2013 09:03 A service of the U.S. National Institutes of Health Trial record 1 of 1 for: UKM08_0057 Previous Study Return to List Next Study Prospective Trial for the Diagnosis and Treatment
More informationSpecializing Care for Adolescent Oncology Patients
Specializing Care for Adolescent Oncology Patients Susan D. Flynn Oncology Fellowship Kaitlin Byrne August 3, 2018 Question Amongst pediatric patients ages 1-18, is the implementation of individualized
More informationRESEARCH COMMUNICATION. Childhood Cancer Incidence and Survival , Thailand: Study from the Thai Pediatric Oncology Group
Childhood Cancer Incidence and Survival 2003-2005, Thailand RESEARCH COMMUNICATION Childhood Cancer Incidence and Survival 2003-2005, Thailand: Study from the Thai Pediatric Oncology Group Surapon Wiangnon
More informationPsychosocial Outcomes and Health-Related Quality of Life in Adult Childhood Cancer Survivors: A Report from the Childhood Cancer Survivor Study
435 Psychosocial Outcomes and Health-Related Quality of Life in Adult Childhood Cancer Survivors: A Report from the Childhood Cancer Survivor Study Lonnie K. Zeltzer, 1 Qian Lu, 1 Wendy Leisenring, 3 Jennie
More informationHealth-Related Quality of Life Among Children With Cancer in Hyderabad, India
Original Article Health-Related Quality of Life Among Children With Cancer in Hyderabad, India Susmitha Chirivella 1, Senthil Rajappa 2, Sudha Sinha 3, Tim Eden 4 and Ronald D. Barr 5 1 School of Medicine,
More informationChildhood Cancer Statistics, England Annual report 2018
Childhood Cancer Statistics, England Annual report 2018 Report on behalf of the Children, Teenagers and Young Adults Expert Advisory Group, National Cancer Registration and Analysis Service 1 About Public
More informationNew Surgical Oncology Clinic at Nationwide Children s Hospital
Hematology/Oncology & BMT New Surgical Oncology Clinic at Nationwide Children s Hospital This clinic offers convenient, comprehensive care for patients with cancer. Here, in one visit, pediatric patients
More informationTUESDAY, 18th OCTOBER, 2016 / DAY -2. THE SPENCER HOTEL Hall A Hall B (St. Lukes Hospital)
Legend: Keynote Educational Meet the Expert (MTE) Paediatric Psycho-Oncology () Opening/Closing Award Session Free Paper Session (FPS) Session Satellite SIOPe GA SIOP ABM Late Breaker Session Networking
More informationSurvival in Teenagers and Young. Adults with Cancer in the UK
Survival in Teenagers and Young Adults with Cancer in the UK Survival in Teenagers and Young Adults (TYA) with Cancer in the UK A comparative report comparing TYA cancer survival with that of children
More informationSubspecialty Inpatient Rotation: Pediatric Oncology at Memorial Sloan Kettering Cancer Center Senior Resident
Subspecialty Inpatient Rotation: Pediatric Oncology at Memorial Sloan Kettering Cancer Center Senior Resident Residents: Pediatric residents at the PL3 level Prerequisites: Successful completion or waiver
More informationRESEARCH COMMUNICATION. Childhood Cancer Burden in Part of Eastern India-Population Based Cancer Registry Data for Kolkata ( )
Burden of Childhood Cancer in the Population Based Cancer Registry, Kolkata (1997-2004) RESEARCH COMMUNICATION Childhood Cancer Burden in Part of Eastern India-Population Based Cancer Registry Data for
More informationIntroduction Pediatric malignancies Changing trends & Radiation burden Radiation exposure from PET/CT Image gently PET & CT modification - PET/CT
Introduction Pediatric malignancies Changing trends & Radiation burden Radiation exposure from PET/CT Image gently PET & CT modification - PET/CT protocols Tips Leukaemia / lymphoma: ~ 35% acute lymphoblastic
More informationTUESDAY, 18th OCTOBER, 2016 / DAY -2
Legend: Keynote Educational PODC Symposium Meet the Expert (MTE) Paediatric Psycho-Oncology () Opening/Closing Award Session Free Paper Session (FPS) Session Satellite Symposium SIOPe GA SIOP ABM Late
More informationReport on Cancer Statistics in Alberta. Childhood Cancer
Report on Cancer Statistics in Alberta Childhood Cancer November 2009 Surveillance - Cancer Bureau Health Promotion, Disease and Injury Prevention Report on Cancer Statistics in Alberta - 2 Purpose of
More informationChapter 1 MAGNITUDE AND LEADING SITES OF CANCER
Chapter 1 MAGNITUDE AND LEADING SITES OF CANCER Table 1.1 gives the total number of cancers diagnosed at five different hospital based cancer registries (HBCRs), over the period of two years from 1st January
More informationWe care for you. The University Hospital Muenster, Germany
We care for you. The University Hospital Muenster, Germany * International LivCom Award 2004 The University Hospital Muenster, Germany (UKM)......located within the the most liveable city world-wide *
More informationWHAT ARE PAEDIATRIC CANCERS
WHAT ARE PAEDIATRIC CANCERS INTRODUCTION Childhood cancers are RARE 0.5% of all cancers in the West Overall risk that a child will develop cancer during first 15 years of life is 1 in 450 and 1 in 600
More informationEvidence tables from the systematic literature search for premature ovarian insufficiency surveillance in female CAYA cancer survivors.
Evidence tables from the systematic literature search for premature ovarian insufficiency surveillance in female CAYA cancer survivors. Who needs surveillance? Chiarelli et al. Early menopause and Infertility
More informationUK Musculoskeletal Oncology: Something for All Ages. Lars Wagner, MD Pediatric Hematology/Oncology University of Kentucky
UK Musculoskeletal Oncology: Something for All Ages Lars Wagner, MD Pediatric Hematology/Oncology University of Kentucky Pediatric-Type Sarcomas of Bone and Soft Tissue The incidence of sarcoma continues
More informationChildhood cancer survival : Dr. Behçet Uz Children s Hospital registry
Turkish Journal of Cancer Vol.30/ No. 2/2000 Childhood cancer survival 1990-1997: Dr. Behçet Uz Children s Hospital registry ÖZNUR DÜZOVALI 1, RAGIP ORTAÇ 2, İRFAN KARACA 3, NAZİHAT ARGON 4, YASEMİN USLU
More informationSIOP Europe the European Society for Paediatric Oncology European Network for Cancer Research in Children and Adolescents
the European Society for Paediatric Oncology encca European Network for Cancer Research in Children and Adolescents EUROPEAN TRAINING PROGRAMME IN PAEDIATRIC HAEMATOLOGY AND ONCOLOGY EUROPEAN BOARD OF
More informationPsychosocial Late Effects. of Childhood Cancer. Matt Bitsko, Ph.D Departments of Pediatrics and Psychology
Psychosocial Late Effects of Childhood Cancer. Matt Bitsko, Ph.D Departments of Pediatrics and Psychology Learning Objectives: The learner will be able to identify the most common psychosocial late effects
More information28 OI November December A Medical Home for Adolescents and Young Adults with Cancer
28 OI November December 2013 www.accc-cancer.org A Medical Home for Adolescents and Young Adults with Cancer By Douglas S. Hawkins, MD Our team consists of more than 30 doctors specializing in cancers
More informationPediatric Oncology. Vlad Radulescu, MD
Pediatric Oncology Vlad Radulescu, MD Objectives Review the epidemiology of childhood cancer Discuss the presenting signs and symptoms, general treatment principles and overall prognosis of the most common
More informationChallenges in studying risk factors for childhood cancer
Challenges in studying risk factors for childhood cancer Julie A. Ross, Ph.D. Professor and Director, Division of Epidemiology & Clinical Research Department of Pediatrics, University of Minnesota & Masonic
More informationCURRENTLY ENROLLING ONCOLOGY TREATMENT STUDIES (as of 4/27/2017)
CURRENTLY ENROLLING ONCOLOGY TREATMENT STUDIES (as of 4/27/2017) Leukemia AALL0932 closed after Induction Treatment of Patients with Newly Diagnosed Standard Risk B-Lymphoblastic Leukemia (B-ALL) or Localized
More informationHaematopoietic stem cell transplantation (SCT)
HAEMATOPOIETIC TEM CELL TRANPLANTATION FOR CHILREN IN BELGIUM Marie-Françoise resse 1 & Yves Beguin 2 1 epartment of Paediatrics, ivision of Hemato-Oncology, UHOPL, University of Liege, Liège, Belgium;
More informationPediatrics -Proton Beam Therapy in Children -
Pediatrics -Proton Beam Therapy in Children - Beate Timmermann, M.D. West German Proton Therapy Centre Essen Germany Preview Survival Toxicity Why protons? (theoretically) Experiences so far (clinically)
More informationΤhe unique constellation of tumors in AYA: Not an adult, not a child
Τhe unique constellation of tumors in AYA: Not an adult, not a child Giannis Mountzios MSc, PhD Medical Oncologist 251 General Aiforce Hospital 2 nd Oncology Department, Henry Dunant Hospital Centre Athens,
More informationBreast Cancer in Childhood Cancer Survivors: The Impact of Screening on Morbidity
Breast Cancer in Childhood Cancer Survivors: The Impact of Screening on Morbidity WORKING GROUP: This report will be written within the Cancer Control Working Group with oversight from the Second Malignant
More informationEPIDEMIOLOGICAL REVIEW CANCERS AMONG CHILDREN AND ADOLESCENTS AT A CANCER HOSPITAL IN PAKISTAN
EPIDEMIOLOGICAL REVIEW CANCERS AMONG CHILDREN AND ADOLESCENTS AT A CANCER HOSPITAL IN PAKISTAN Farhana Badar, Shahid Mahmood Cancer Registry and Clinical Data Management, Shaukat Khanum Memorial Cancer
More informationEpidemiology of Childhood Cancers: Challenges and Opportunities Prof Tezer Kutluk MD PhD, FAAP President UICC, Union for International Cancer Control
Epidemiology of Childhood Cancers: Challenges and Opportunities Prof Tezer Kutluk MD PhD, FAAP President UICC, Union for International Cancer Control Moscow, 02 th October 2015 Oncology Hospital Children
More informationSOLID TUMOURS IN CHILDHOOD
SOLID TUMOURS IN CHILDHOOD Fareed Omar Paediatric Oncology Steve Biko Academic hospital Introduction 1 Introduction Lymphomas and Leukemias make up about 40% of all childhood Cancers (Systemic cancers)
More informationDisturbances of female reproductive system in survivors of childhood cancer
Disturbances of female reproductive system in survivors of childhood cancer Assoc. Prof. Zana Bumbuliene VU Faculty of Medicine Clinic of Obstetrics and Gynaecology 13 SEP 2014 Introduction Cancer is the
More informationTitle: Characterization of drinking in childhood cancer survivors compared to general population
Title: Characterization of drinking in childhood cancer survivors compared to general population Working Group and Investigators: Anne Lown, Rob Goldsby, and Dan Dohan Background and Rationale: During
More informationRadiation Oncology Study Guide
Radiation Oncology Study Guide For the Initial CertificationQualifying (Computer-Based) Examination General and Radiation Oncology This examination is designed to assess your understanding of the entire
More informationChildhood Cancer Report on Cancer Statistics in Alberta. December Cancer Care. Cancer Surveillance
December 12 1 Report on Cancer Statistics in Alberta Acknowledgements 2 This report was made possible through Alberta Health Services,, and the many contributions of staff and management across Alberta
More informationChildhood Cancer: A Parent's Guide To Solid Tumor Cancers, 2nd Edition PDF
Childhood Cancer: A Parent's Guide To Solid Tumor Cancers, 2nd Edition PDF This second edition of the most complete parent guide available, features detailed and precise medical information about solid
More information5/2/2016. Caring for Adolescents and Young Adults with Cancer. Objectives. AYA Oncology. Cancer Incidence: SEER 18, , ages
Objectives Caring for Adolescents and Young Adults with Cancer Oncology Nursing: Planting Seeds of Hope and Healing May 4 th, 2016 Describe distinctive aspects of disease biology in AYA population List
More informationCHILDHOOD CANCER SURVIVOR STUDY ANALYSIS CONCEPT PROPOSAL
CHILDHOOD CANCER SURVIVOR STUDY ANALYSIS CONCEPT PROPOSAL 1. Study title: Subsequent neoplasms among survivors of childhood cancer not previously treated with radiation 2. Working group and investigators:
More informationDr Sneha Shah Tata Memorial Hospital, Mumbai.
Dr Sneha Shah Tata Memorial Hospital, Mumbai. Topics covered Lymphomas including Burkitts Pediatric solid tumors (non CNS) Musculoskeletal Ewings & osteosarcoma. Neuroblastomas Nasopharyngeal carcinomas
More informationTHE BURDEN OF CANCER IN NEBRASKA: RECENT INCIDENCE AND MORTALITY DATA
THE BURDEN OF CANCER IN NEBRASKA: RECENT INCIDENCE AND MORTALITY DATA Presented by: Bryan Rettig, MS Nebraska Dept. of Health & Human Services Division of Public Health May 31, 2017 Nebraska Cancer Registry
More informationPERFORMANCE AFTER HSCT Mutlu arat, md ıstanbul bilim un., dept. hematology ıstanbul, turkey
PERFORMANCE AFTER HSCT Mutlu arat, md ıstanbul bilim un., dept. hematology ıstanbul, turkey Joint Educational Meeting of the EBMT Severe Aplastic Anaemia, Late Effects and Autoimmune Diseases Working Parties
More informationCancer Incidence in Belgium
Cancer Incidence in Belgium 2010 Special issue Cancer in Children and Adolescents Belgian Cancer Registry Cancer Incidence in Belgium 2010 Special issue Cancer in Children and Adolescents Belgian Cancer
More informationAYA Cancer: The Lost Tribe
AYA Cancer: The Lost Tribe Date: February 22, 2010 Leah Kroon, MN, RN None 1. Discuss why AYA cancer outcomes are not keeping up with pediatric and/or adult cancer patient outcomes 2. Identify special
More informationCURRENTLY ENROLLING ONCOLOGY TREATMENT STUDIES (as of )
Leukemia AALL0932 closed after Induction CURRENTLY ENROLLING ONCOLOGY TREATMENT STUDIES (as of 10.10.2017) Treatment of Patients with Newly Diagnosed Standard Risk B-Lymphoblastic Leukemia (B-ALL) or Localized
More informationReproductive function in cancer survivors
Reproductive function in cancer survivors Professor W Hamish Wallace hamish.wallace@nhs.net Symposium 20: Endocrine consequences of childhood cancer treatment Liffey Hall 2, 0905 19 May 2015 CONFLICT OF
More informationMethoden / Methods inc. ICCC-3 105
Methoden / Methods inc. ICCC-3 105 Internationale Klassifikation der Krebserkrankungen bei Kindern (ICCC-3) Zuordnung von ICD-O-3-Codes für Morphologie und Topographie zu diagnostischen Kategorien International
More informationFamily education programme nephrotic syndrome
programme Pipilotta und der Nierendetektiv Marcus R. Benz 1, E.-M. Rüth 2, F. Kusser 1, T. Volkmar 1, H. Fehrenbach 3, D. Kleinert 3, J. Dötsch 2, L.T. Weber 1 1 Paediatric Nephrology, Dr. von Haunersches
More informationChildren with Cancer: Animal- Assisted Therapy and Coping with the Illness. Victoria Cooper. Temple University. Foundations of TR Practice / 2103
Running Head: Children with Cancer Children with Cancer: Animal- Assisted Therapy and Coping with the Illness Victoria Cooper Temple University Foundations of TR Practice / 2103 April 14, 2011 Dr. Heather
More informationLong-term PHARMacovigilance for Adverse effects in Childhood arthritis focusing on Immune modulatory drugs
Long-term PHARMacovigilance for Adverse effects in Childhood arthritis focusing on Immune modulatory drugs EMEA meeting, june 28, 200 A European collaboration between pediatric rheumatology centers regarding
More informationLong term toxicity of treatment. Laurence Brugieres Children and Adolescent Oncologic department
Long term toxicity of treatment Laurence Brugieres Children and Adolescent Oncologic department Most TYA with cancer are cured from their malignancy TRAMA 2016 2 What are the consequences of cancer treatment?
More informationConnecting with the World:
Connecting with the World: Updates and Insights from Multicenter Study of Rare Disease in the Adult Airway November 3, 2016 Alexander Gelbard MD Vanderbilt University School of Medicine 4th Annual Contemporary
More informationOverview of 2010 Hong Kong Cancer Statistics
Overview of 2010 Hong Kong Cancer Statistics Cancer Registration in Hong Kong The Hong Kong Cancer Registry has since the 1960s been providing population-based cancer data for epidemiological research
More informationOVERVIEW OF PAEDIATRIC SURGICAL ONCOLOGY SERVICES IN KENYA
OVERVIEW OF PAEDIATRIC SURGICAL ONCOLOGY SERVICES IN KENYA PROF. ROBERT TENGE KUREMU Paediatric Surgeon, Moi University School of Medicine KENYA PAEDIATRIC ASSOCIATION ANNUAL SCIENTIFIC CONFERENCE ELDORET
More informationThe Development of Pediatric Oncology in Turkey:
The Development of Pediatric Oncology in Turkey: Improving Childhood Cancer Survival Rate Through Professional Training and Education Prof. Dr. Tezer Kutluk, MD PhD, FAAP UICC president & Hacettepe University
More informationChallenging Paediatric Brain Tumours. ASP Belfast March 2017 Dr Jane Pears Consultant Paediatric Oncologist, Dublin
Challenging Paediatric Brain Tumours ASP Belfast March 2017 Dr Jane Pears Consultant Paediatric Oncologist, Dublin Overview (i) Paediatric malignancy (ii) Central nervous system tumours (iii) Diffuse Intrinsic
More informationCancer in adolescents and Young Adults
17 th ESO-ESMO Masterclass in Clinical Oncology 24-29 March 2018, Cancer in adolescents and Young Adults Laurence Brugières Gustave Roussy Cancer Center Villejuif, France Cancer in TYA A rare disease in
More informationHealth Consultation CHILDHOOD CANCER INCIDENCE UPDATE: A REVIEW AND ANALYSIS OF CANCER REGISTRY DATA, FOR
Health Consultation CHILDHOOD CANCER INCIDENCE UPDATE: A REVIEW AND ANALYSIS OF CANCER REGISTRY DATA, 2001-2005 FOR TOWNSHIP OF TOMS RIVER, OCEAN COUNTY, NEW JERSEY AUGUST 20, 2008 U.S. DEPARTMENT OF HEALTH
More informationPediatric Cancer in Idaho,
Pediatric Cancer in Idaho, 1996-2006 Although relatively rare in comparison with cancer in older adults, cancer is the second leading cause of death in persons aged 1-14 years. The epidemiology of cancer
More informationEpidemiology of AYA tumours. Dan Stark, MD Consultant in Medical Oncology Leeds UK
Epidemiology of AYA tumours Dan Stark, MD Consultant in Medical Oncology Leeds UK Summary Why we should study the epidemiology of AYA tumours What is already known What is not already known and is important
More informationPEDIATRIC CANCER IN FLORIDA
PEDIATRIC CANCER IN FLORIDA 1981-2 paulo pinheiro jaclyn button lora fleming youjie huang brad wohler jill mackinnon james wilkinson PEDIATRIC CANCER IN FLORIDA 1981-2 Paulo S Pinheiro, MD MSc CTR Jaclyn
More informationClinical Commissioning Policy: Haematopoietic Stem Cell Transplantation. December Reference : NHSCB/B4/a/1
Clinical Commissioning Policy: Haematopoietic Stem Cell Transplantation December 2012 Reference : NHSCB/B4/a/1 NHS Commissioning Board Clinical Commissioning Policy: Haematopoietic Stem Cell Transplantation
More informationAcknowledgements and Disclaimer
Infant Cancers in California, 1988 2011 Acknowledgements and Disclaimer The collection of cancer incidence data used in this study was supported by the California Department of Public Health as part of
More informationNational Horizon Scanning Centre. Rituximab (MabThera) for chronic lymphocytic leukaemia. September 2007
Rituximab (MabThera) for chronic lymphocytic leukaemia This technology summary is based on information available at the time of research and a limited literature search. It is not intended to be a definitive
More informationMore than 80% of the 200,000 new cases of
R E S E A R C H P A P E R Childhood Cancer Incidence in India Betweem 2012 and 2014: Report of a Population-based Cancer Registry SUMAN DAS, DILIP KUMAR PAUL, KUMAR ANSHU AND SUBHAJIT BHAKTA From Department
More informationFACULTY MEMBERSHIP APPLICATION Tulane Cancer Center
FACULTY MEMBERSHIP APPLICATION Tulane Cancer Center 1430 Tulane Ave., Box SL-68, New Orleans, LA 70112-2699 J. Bennett Johnston Building, Mezzanine (Floor 1A), Suite A102 (504) 988-6060, fax (504) 988-6077,
More informationPaediatric Oncology: Past, present and future
Paediatric Oncology: Past, present and future Jan Millar CNS Children s Haematology Oncology Centre April 15th 2010 The past I believe that there is merit in looking at the past in order to have a perspective
More informationPast Chapter Summaries Educational Topics Summary
Below is a comprehensive summary of all of the different Educational Topics our Local Chapters have presented and/or provided 2014 1. The most powerful force in nursing 2. Hope and meaning in life in adolescent
More informationLong-term PHARMacovigilance for Adverse effects in Childhood arthritis focusing on Immune modulatory drugs
Long-term PHARMacovigilance for Adverse effects in Childhood arthritis focusing on Immune modulatory drugs EMEA meeting, december 4, 2009 A European collaboration between pediatric rheumatology centers
More informationTreatment of Paediatric Cancers in Hong Kong: An Interim Report
HK J Paediatr (new series) 2001;6:110-115 in Hong Kong: An Interim Report CK LI, GCF CHAN, KW CHIK, SY HA, YL LAU, ACW LEE, CY LEE, CK LI, SC LING, CW LUK, MMK SHING, HL YUEN, PMP YUEN Abstract Key words
More informationSolid tumors in young children in Moscow Region of Russian Federation
doi:10.2478/v10019-007-0037-2 Solid tumors in young children in Moscow Region of Russian Federation Denis Y Kachanov 1,2, Konstantin V Dobrenkov 2, Tatyana V Shamanskaya 1,2, Ruslan T Abdullaev 1,2, Evgueniya
More informationChildhood Cancer Survivor Study Analysis Concept Proposal
Title: Multiple Subsequent Neoplasms Working Group and Investigators: Childhood Cancer Survivor Study Analysis Concept Proposal This proposed publication will be within the Second Malignancy Working Group
More informationCHILDHOOD CANCER SURVIVAL STUDY CONCEPT PROPOSAL
Version: March 3, 2006 CHILDHOOD CANCER SURVIVAL STUDY CONCEPT PROPOSAL I- Title: Neurocognitive and Psychosocial Correlates of Adaptive Functioning in Survivors of Childhood Leukemia and Lymphoma. II-
More informationPEDIATRIC CANCER IN IDAHO
PEDIATRIC CANCER IN IDAHO 2001-2010 May 2013 A Publication of the ACKNOWLEDGMENTS The Idaho Hospital Association (IHA) contracts with, and receives funding from, the Idaho Department of Health and Welfare,
More informationPEDIATRIC CANCER IN IDAHO
PEDIATRIC CANCER IN IDAHO 1999-2008 May 2011 A Publication of the ACKNOWLEDGMENTS The Idaho Hospital Association (IHA) contracts with, and receives funding from, the Idaho Department of Health and Welfare,
More informationModule Guide 2017/18
MSc in Oncology Including PG Certificate and PG Diploma Cancer Treatments 2 Module Guide 2017/18 Part B Clinical Sciences Contents Module details 1.1 Module overview... 3 1.2 Module specification... 3
More informationThe 100,000 Genomes Project
The 100,000 Genomes Project Dr Matina Prapa, Scientific co ordinator Genomics England Clinical Interpretation Partnership William Harvey Research Institute Queen Mary University of London Genomics England
More informationAccess to Clinical Trials International Initiatives
Access to Clinical Trials International Initiatives Stefan Bielack Cooperative Osteosarcoma Study Group COSS Stuttgart Cancer Center Klinikum Stuttgart Olgahospital Zentrum für Kinder-, Jugend- und Frauenmedizin
More informationÉpidémiologie des sarcomes en Belgique
1 Épidémiologie des sarcomes en Belgique Dr. Liesbet Van Eycken 12 es journées annuelles du GSF-GETO Oud Sint-Jan Bruges, 22-24 juin 2016 Overview Introduction Descriptive epidemiology Incidence Age specific
More informationThe International Classification of Diseases for Oncology (ICD-O) is
1425 COMMENTARY Classification Schemes for Tumors Diagnosed in Adolescents and Young Adults Ronald D. Barr, M.B., Ch.B., M.D. 1 3 Eric J. Holowaty, M.D., M.Sc. 4 Jillian M. Birch, B.Sc., M.Sc., Ph.D. 5
More informationI SURVIVED CANCER, BUT SCHOOL IS KILLING ME ANNE MAUCK, CPNP, CPON NOVEMBER 2017
I SURVIVED CANCER, BUT SCHOOL IS KILLING ME ANNE MAUCK, CPNP, CPON NOVEMBER 2017 OBJECTIVES DESCRIBE SURVIVORSHIP DESCRIBE SPECIFIC CANCER TREATMENTS AS THEY RELATE TO SCHOOL FUNCTION DISCUSS THE IMPACT
More informationChildhood cancers in Chennai, India, : Incidence and survival
Int. J. Cancer: 122, 2607 2611 (2008) ' 2008 Wiley-Liss, Inc. Childhood cancers in Chennai, India, 1990 2001: Incidence and survival Rajaraman Swaminathan 1 *, Ranganathan Rama 1 and Viswanathan Shanta
More informationdiagnosis and initial treatment at one of the 27 collaborating CCSS institutions;
Peer-delivered smoking counseling for childhood cancer survivors increases rate of cessation: the Partnership for Health Study Emmons K M, Puleo E, Park E, Gritz E R, Butterfield R M, Weeks J C, Mertens
More informationNew RT techniques: childhood cancer
Methodology for literature review, data mining, modeling of dose response in pediatric radiation oncology Søren M Bentzen, Ph.D., D.M.Sc. Division of Biostatistics and Bioinformatics, UMGCC Shared Biostatistics
More information1. Study Title. Exercise and Late Mortality in 5-Year Survivors of Childhood Cancer: a Report from the Childhood Cancer Survivor Study.
CCSS Analysis Concept Proposal Exercise, Mortality, & Childhood Cancer 1 1. Study Title. Exercise and Late Mortality in 5-Year Survivors of Childhood Cancer: a Report from the Childhood Cancer Survivor
More informationPRELIMINARY PROGRAM MAY 31 - JUNE 4, 2019
MONDAY, JUNE 3, 2019 7:30 AM - 9:15 AM HIGHLIGHTS OF THE DAY 8:00 AM - 9:00 AM S 8:00 AM - 9:15 AM S S 8:00 AM - 11:00 AM S Highlights of the Day Session II Bringing New and Innovative Glioblastoma Treatments
More informationCorporate Medical Policy
Corporate Medical Policy Hematopoietic Stem-Cell Transplantation for Solid Tumors of File Name: Origination: Last CAP Review: Next CAP Review: Last Review: hematopoietic_stem-cell_transplantation_for_solid_tumors_childhood
More information