ASCONA 07/11/08 PAEDIATRIC ONCOLOGY. 2 nd ESO-SIOPE MASTERCLASS IN November 2008 Ascona, Switzerland

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1 MASTERCLASS ASCONA 07/11/08 2 nd ESO-SIOPE MASTERCLASS IN PAEDIATRIC ONCOLOGY 7-13 November 2008 Ascona, Switzerland Chair: R. Riccardi, IT - M.C.G. Stevens, UK - A. Eggert, DE Educational Advisor: W. Gatzemeier, IT

Aims and objectives Following the success of the first Masterclass in 2006, ESO and SIOP-Europe are pleased to announce the second Masterclass in Paediatric Oncology.

2 Aims and objectives Following the success of the first Masterclass in 2006, ESO and SIOP-Europe are pleased to announce the second Masterclass in Paediatric Oncology. This clinically-oriented educational programme has been designed for young pediatric oncologists who wish to improve their skills in the management of paediatric oncology patients. It is designed to offer a unique learning experience providing practice-oriented training. Teaching format The Masterclass offers plenary lectures focusing on state-of-the-art treatment and concluding with take-home messages. Case presentations prepared by all the participants will be discussed between the participants and the experts. All sessions will be closed by the chairman with a summary to identify key learning points. FACULTY D.C. Aronson, Academic Medical Center, Emma Children s Hospital, Amsterdam, NL S. Bielack, Olgahospital, Dept. of Oncology, Stuttgart, DE H.N. Caron, Academic Medical Center, Emma Children's Hospital, Amsterdam, NL G. Cecchetto, Clinico-Ospedaliero di Padova, Padua, IT F. Doz, Institut Curie, Paris, FR A. Eggert, Universitäts Kinderklinik, Essen, DE A. Ferrari, Fondazione IRCCS Istituto Nazionale dei Tumori, Div. of Paediatric Oncology, Milan, IT W. Gatzemeier, Salvatore Maugeri Foundation, Pavia, IT M. Gaze, University College Hospital, London, UK F. Giangaspero, Università " La Sapienza" di Roma, Rome, IT G. Gosheger, University of Muenster, Tumor and Revision Surgery Dept. of Orthopaedics, DE T. Jaspan, University of Nottingham, Imaging Centre, UK D. Körholz, Universitätsklinikum Halle, Halle, DE R. Ladenstein, Children's Cancer Research Institute, Vienna, AT T. Lehrnbecher, Paediatric Haematology and Oncology, University of Frankfurt, Germany, DE K. McHugh, Great Ormond Street Hospital, Department of Radiology, UK B. Morland, Birmingham Childrens Hospital, Dept. of Oncology, Birmingham, UK M. Paulussen, University Children's Hospital Basel, CH K. Pritchard Jones, Royal Marsden Hospital, Surrey, UK R. Riccardi, Policlinico Universitario A. Gemelli, Div. of Paediatric Oncology, Rome, IT M.C.G. Stevens, Royal Hospital for Children, Dept. of Oncology, Bristol, UK G. Vassal, Institut Gustave Roussy, Dept. of Paediatrics and Clinical Pharmacology Lab, Villejuif, FR M. Vinchon, CHU Lille, Neurosurgery, Lille, FR D.A. Walker, University of Nottingham, Division of Child Health, UK

3 SATURDAY, 8 NOVEMBER NEUROBLASTOMA A. Eggert, DE 8:30 Epidemiology, pathology and embryology H. Caron, NL 9:15 Molecular genetics and biology A. Eggert, DE 10:00 Staging and prognostic classification A. Eggert, DE 10:30 Coffee break 11:00 Overview of treatment strategies in Europe + US R. Ladenstein, AT 11:15 HR treatment R. Ladenstein, AT 12:00 LR treatment: which groups not to treat? A. Eggert, DE 12:20 Novel strategies H. Caron, NL 12:45 Summary to identify key learning points A. Eggert, DE 17:30 Key note lecture: How to develop a new drug in pediatric oncology? G. Vassal, FR SUNDAY, 9 NOVEMBER CNS TUMOURS R. Riccardi, IT 8:30 Epidemiology and pathology F. Giangaspero, IT 9:15 Radiology: morphological and non-morphological imaging of brain tumours T. Jaspan, UK 10:00 Brain tumour related syndromes D.A. Walker, UK 10:15 Role of neurosurgery in modern approach to treatment of CNS tumours M. Vinchon, FR 10:45 Coffee break 11:15 Biology of medulloblastoma into clinical practice F. Doz, FR 12:00 Low grade glioma: the case for multidisciplinary approach D.A. Walker, UK 12:30 Ethics and communication of CNS tumour treatment R. Riccardi, IT 12:45 Summary to identify key learning points R. Riccardi, IT 17:30 Key note lecture: Clinical Trials K. Pritchard Jones, UK

4 MONDAY, 10 NOVEMBER WILMS AND HODGKIN S D. Körholz, DE - K. Pritchard Jones, UK 8:30 Overview of renal tumours of childhood and approaches to treatment of Wilms tumour K. Pritchard Jones, UK 9:15 Imaging and Diagnosis of Renal Tumours of Childhood K. McHugh, UK 9:30 Surgical Issues in Wilms tumour G. Cecchetto, IT 10:00 Radiotherapy in Wilms tumour - who needs it and how much? M. Gaze, UK Summary to identify key learning points K. Pritchard Jones, UK 10:45 Coffee break 11:15 Evolution of treatment strategy for children and adolescents with classical Hodgkin s lymphoma from 1978 to present day D. Körholz, DE 12:00 New concepts in diagnostic and Treatment of Lymphophocyte predominant Hodgkin s lymphoma D. Körholz, DE 12:45 Summary to identify key learning points D. Körholz, DE 17:30 Key note lecture: Advances in imaging for solid tumours K. McHugh, UK TUESDAY, 11 NOVEMBER SOFT TISSUE SARCOMA M.C.G.Stevens, UK 8:30 Introduction to Soft Tissue Sarcoma M.C.G. Stevens, UK 8:50 RMS - treatment and outcome M.C.G. Stevens, UK 9:40 Radiotherapy for RMS M. Gaze, UK 10:10 Imaging in STS K. McHugh, UK 10:30 Coffee break 11:00 Non Rhabdo Soft Tissue Sarcoma A. Ferrari, IT 12:00 Challenges of local control G. Cecchetto, IT (with comments from other members of the faculty) 12:45 Summary to identify key learning points M.C.G. Stevens, UK 17:30 Key note lecture: Conduct of Phase I/II studies: methodological and ethical aspects B. Morland, UK

5 WEDNESDAY, 12 NOVEMBER BONE TUMOURS AND LIVER D. Aronson, NL - S. Bielack, DE 8:30 Pathology, epidemiology and clinical presentation S. Bielack, DE 8:45 Staging S. Bielack, DE 8:55 Biopsy G. Gosheger, DE 9:05 Principles of multimodal therapy M. Paulussen, CH 9:15 Surgery G. Gosheger, DE 9:45 Systemic Treatment: Osteosarcoma and recurrent osteosarcoma S. Bielack, DE 10:10 Systemic Treatment: Ewing tumour and recurrrent Ewing tumours M. Paulussen, CH 10:35 Summary to identify key learning points S. Bielack, DE 10:45 Coffee break 11:15 Liver tumours in children D. Aronson, NL 12:00 Treatment of Hepatoblastoma and HCC D. Aronson, NL 12:45 Summary to identify key learning points D. Aronson, NL 17:30 Key note lecture: The impact of infection on treatment strategies and results? T. Lehrnbecher, DE

GENERAL INFORMATION FOR FURTHER INFORMATION CONTACT: Rita De Martini European School of Oncology Via del Bollo, 4 20123 Milan - Italy Tel: +39 02 8546 4527 - Fax: +39 02 8546 4545 Email:

The successful applicants are granted free registration but the cost of half-board accommodation at the course venue CHF 1000 ( approx EUR 630) for the period 7-13 November 2008 and travel will be

6 GENERAL INFORMATION FOR FURTHER INFORMATION CONTACT: Rita De Martini European School of Oncology Via del Bollo, Milan - Italy Tel: Fax: rdemartini@eso.net - Website: Information and application form available at APPLICATION DEADLINE: 20 June 2008 PARTICIPATION Admittance to the Masterclass is by competitive application. The successful applicants are granted free registration but the cost of half-board accommodation at the course venue CHF 1000 ( approx EUR 630) for the period 7-13 November 2008 and travel will be covered by the participants. All participants will be expected to reside at the course venue and their full participation is compulsory throughout the course. The Masterclass will be taught entirely in English and fluency in English is necessary for admission. IDEAL MASTERCLASS CANDIDATE Age between 30 and 40 years 2-4 years experience in paediatric oncology Involvement in scientific activities and clinical trials Fluency in English HOW TO APPLY Interested oncologists should submit an application form (available on-line at with the following documents by the application deadline: Letter describing motivation for attending the Masterclass Short CV (maximum 2 pages) with list of recent publications Supporting letter from Head of Department / Mentor Abstract (1 page) with proposed presentation of a clinical case relating to one of the main themes of the Masterclass (bone tumours, central nervous system tumours, Hodgkin s disease, liver tumours, neuroblastoma, soft-tissue sarcoma, Wilms tumour) The abstract should be presented in the form of a grand-round clinical discussion rather than a publication report, and describe: Diagnostic considerations Treatment Outcome (follow-up) Up to three questions that the author proposes for discussion by the faculty and participants TRAVEL GRANT ESO and SIOP-E are grateful to the Italian Neuroblastoma Foundation for having provided Travel Grants to mainly support participants coming from countries defined as low-/ lower-middle income economies by the World Bank The request for a travel grant must be mentioned in the letter accompanying the application, indicating the amount needed to cover travel costs.

6 TH ESO-SIOP EUROPE MASTERCLASS IN PAEDIATRIC ONCOLOGY June 2016 Berlin, Germany. Chairs: A. Eggert, DE B. Morland, UK R.

MASTERCLASS 6 TH ESO-SIOP EUROPE MASTERCLASS IN PAEDIATRIC ONCOLOGY Held with the support of 11-16 June 2016 Berlin, Germany Chairs: A. Eggert, DE B. Morland, UK R. Riccardi, IT INTRODUCTION ESO and SIOP-Europe