DIVISION OF CLINCIAL NEUROSCIENCES REGISTER OF INTERESTS

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Mervin Fletcher
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1 DIVISION OF CLINCIAL NEUROSCIENCES REGISTER OF INTERESTS JOANNA M WARDLAW INTEREST 10k from Axaron for data supply Funding from Novartis for octreotide studies to department Reading CT scans for ECASS III; funding to department JMW is the contact reviewer for the Cochrane systematic review of thrombolytic treatment for acute stroke. JMW is a member of the IST-3 management group and leads a collaborative neuro-radiological group assessing the scans of patients entered in the trial. JMW is director of the SHEFC Brain Imaging Research Centre for Scotland. This is located within the Department of Clinical Neurosciences at the University of Edinburgh. The Centre houses a research magnetic resonance scanner which was funded by the UK Research Councils Joint Research Equipment Initiative, supplemented by grants and donations from various other sources including Novartis, Schering, GE and BI. These commercial sources contributed to the purchase of the scanner, but not the running costs or any individual studies. JMW has also attended meetings held by Boehringer Ingelheim to discuss the licencing of rt-pa. She attended as an unpaid independent external adviser but was refunded her travel expenses and the time away from work. JMW has received honorarium from Novartis ( 1,000) for work done in connection with evaluation of a new treatment for acromegally to be used for travel to conferences. JMW received a modest honorarium from BI (n 250) for presenting the Cochrane Thrombolysis Review at the third Advances in Stroke Management meeting in Sardinia, September JMW Register of Interests Page 1 of 5

2 Engineering and Physical Sciences Research Council Computational Modelling and 3D Imaging: Estimation of the Biomechanical Status of Diseased Arteries In-vivo Dr PR Hoskins, Prof. N McDicken, Dr I Marshall, Dr JM Wardlaw, Dr RE Blundell, Dr DJ Webb, Professor A Bradbury, Dr SRJ Maxwell, Dr PL Allan, Dr H Routh 1,361,311 1 May 2001 end 2007 Ref No GR/R 19793/01 The Row Fogo Trust Research studies in stroke and other common brain diseases Dr JM Wardlaw, Dr I Marshall, Dr M Bastin, and the Stroke Research Group 80,000 1 April 2001 to 31 July 2004 Renewed until 31 July 2007 at 192,000 Ref No R35865, Programme Grant Cognitive impairment in schizophrenia a clinical, imaging and genetic study of co-morbidity Professor EC Johnstone (PI), Professor JM Wardlaw, Professor DG Cunningham Owen, Dr SM Lawrie, Dr P Hoare, Dr W Muir 1,462,044 1 August July 2007 Ref No G /56724 Chest, Heart Stroke Scotland Research Fellowship Is blood brain barrier failure the cause of cerebral small vessel disease? Dr AJ Farrall, with Professor JM Wardlaw, Professor MS Dennis 89,500 October 2004 October 2007 University of Edinburgh Principal s elearning Initiative Development of elearning modules in Neuroradiology Professor JM Wardlaw, Dr A Farrall, Dr P White, Mr D Perry, Dr R Sellar, Dr D Summers, Dr P Armitage 118, February 2004 December 2007 JMW Register of Interests Page 2 of 5

3 Chief Scientist Office Is lacunar stroke due to disordered cerebral arteriolar permeability? Professor JM Wardlaw, Professor MS Dennis, Dr Paul Armitage, Professor G Lowe, Professor B Dhillon, Dr C Sudlow, Professor P Mitchell 162,618 1 December December 2007 Ref No CZB/4/281 NeuroGrid an escience Consortium in Neuroimaging Professor J Geddes (PI), and, alphabetically, Professor P Bath, Dr N Fox, Dr N Goddard, Professor J Hajnal, Dr D Hill, Professor E Johnstone, Dr S Lawrie, Mr D Perry, Dr R Proctor, Professor T Rodden, Professor M Rossor, Dr P Rothwell, Professor P Sandercock, Professor J M Wardlaw 2,185,687 1 March 2004 August 2008 Ref No G Chief Scientist Office - Fellowship Making sense of diagnostic meta-analyses using carotid artery imaging as a template Ms F Chappell 114,598 April 2005 March 2008 Ref No CZF/1/23 Third International Stroke Trial: IST-3 Professor P Sandercock, Professor M Dennis, Professor R Lindley, Professor J Wardlaw 2,800,000 April 2005 March 2010 Ref No G The Wellcome Trust Research Training Fellowship Can retinal vascular abnormalities shed light on pathophysiology of lacunar stroke? Dr Fergus Doubal 180,000 (approximately) March 2005 July 2008 Ref No JMW Register of Interests Page 3 of 5

4 The Wellcome Trust Integrated image data storage and processing facilities to support research in clinical neuroscience Dr I Marshall, Professor JM Wardlaw, Dr SM Lawrie, Professor IJ Deary, Dr AS Trew, Professor S Dela Salla 443, Ref No GR National Institutes of Health MRI and DTI-Based Tools for Analyzing White Matter Variation. A multidisciplinary study to develop software tools to segment and identify bundles of neural fibres in the brain Bastin ME, Armitage PA, Wardlaw JM, Whittle IR $277, September July 2009 NIBIB R01 EB A1 Help the Aged/Research into Ageing Major Gift Campaign. The Disconnected Mind Professor I Deary (PI), Dr K Horsburgh, Professor J McCulloch, Professor R Morris, Dr J Starr, Professor J Wardlaw 11, January Help the Aged/Research into Ageing Sydney De Haan Award Professor I Deary (PI), Dr K Horsburgh, Professor J McCulloch, Professor R Morris, Dr J Starr, Professor J Wardlaw 491,147 1 May Improving the management of blood pressure in acute stroke: the Efficacy of Nitric Oxide in Stroke (ENOS) Trial Professor P Bath (PI), Professor D Thomas, Professor K Lees, Professor J Wardlaw, Professor S Pocock, Professor D Whynes 3,174,379 MRC ( 3,962,153 FEC) Five years from 1 July 2006 Ref No G JMW Register of Interests Page 4 of 5

5 Chief Scientist Office A systematic review of experimental models of lacunar stroke: Linking models to the human disease Professor J Wardlaw (PI), Dr C Sudlow, Professor J McCulloch 52,569 Nine months from 1 March 2007 Ref No CZB/4/517 The Stroke Association Brain and body temperature after acute stroke Professor J Wardlaw (PI), Professor M Dennis, Dr I Marshall, Professor G Lowe, Dr S Keir 112,202 Over 24 months from 2007 Ref TSA 2006/11 SINAPSE Scottish Imaging Network: A Platform for Scientific Excellence Joint funding application from the universities of Aberdeen, Dundee, Edinburgh, Glasgow, St Andrews and Stirling 7,357,784 August 2007 August 2012 WYETH/TMRI LTD Joint funding application from the universities of Aberdeen, Edinburgh, and Glasgow Advanced brain imaging to assess salvageable tissue in acute stroke diagnosis and prognosis indicators Wardlaw J M, Muir K, MacLeod M J 722,965 August 2007 July 2008 NS-EU-082 JMW Register of Interests Page 5 of 5

Applications in Disease

Applications in Disease Semester 1 / Autumn 10 Credits Each Course is composed of Modules & Activities. Modules: Systematic review methodology IMSc NI4R Neurosurgery IMSc NI4R Stroke NI4R Applied MR in