Critical Appraisal Worksheets 1. Critical Appraisal Worksheets

Transcription

1 Critical Appraisal Worksheets 1 Critical Appraisal Worksheets

2 Critical Appraisal Worksheets 2..Primary Studies

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6 Critical Appraisal Worksheets 6 CRITICAL REVIEW FORM ON APPLICABILITY I. BIOLOGIC: 1. Are there pathophysiologic differences in the illness under study that may lead to a diminished treatment response? 2. Are there patient differences that may diminish the treatment response? II. SOCIAL AND ECONOMIC: 1. Are there important differences in patient compliance that may diminish the treatment response? 2. Are there important differences in provider compliance that may diminish the treatment response? III. EPIDEMIOLOGIC: 1. Do my patients have comorbid conditions that significantly alter the potential benefits and risks of treatment? 2. Are there important differences in untreated patients at risk of adverse outcomes that might alter the efficiency of treatment? References: JAMA 1994; 271: , JAMA 1994; 271:

7 Critical Appraisal Worksheets 7..Integrative Studies

8 Critical Appraisal Worksheets 8 CRITICAL REVIEW FORM FOR A PRACTICE GUIDELINE I. Are the Results Valid? 1. Were all important options and outcomes clearly specified? 2. Was an explicit and sensible process used to identify, select, and combine the evidence? 3. Was an explicit and sensible process used to consider the relative value to different outcomes? 4. Is the guideline likely to account for important recent developments? 5. Has the guidelines been subject to peer review and testing? II. What are the recommendations? 1. Are clear, practical, and important recommendations made? 2. How strong are the recommendations? 3. Could the uncertainty in the evidence or values change the guideline is recommendations? III. Will the results help me in caring for my patients? 1. Is the objective of the guideline consistent with mine? 2. Are the recommendations applicable to my patients? References: JAMA 1995; 274: , JAMA 1995; 274:

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10 Critical Appraisal Worksheets 10 CRITICAL REVIEW FOR HEALTH SERVICES RESEARCH I. Three Initial Questions 1. Were the outcome measures accurate and comprehensive? 2. Were there clearly identified, sensible comparison groups? 3. How well did the compared groups match up on important factors that can affect the outcomes of a health service: 4. Who provided the service? 5. What service was provided? 6. When was the service provided? 7. Where was the service provided? 8. How was the service provided? II. Further Questions 1. Were all important prognostic factors measure? 2. Were measures of patients prognostic factors reproducible and accurate? 3. Were patients similar with respect to these factors? 4. How much difference in outcome(s) remains after adjustment for the prognostic factors? References: JAMA 1996; 275:

11 Critical Appraisal Worksheets 11 CRITICAL REVIEW FORM FOR DECISION ANALYSIS I. Are the Results Valid? 1. Were all important strategies and outcomes included? 2. Was an explicit and sensible process used to assemble the evidence into probabilities? 3. Were the utilities obtained in an explicit and sensible way from credible sources? 4. Was the impact of uncertainty in evidence explored? II. What Are the Results? 1. Does one strategy yield a clinically important gain for patients? If not, is the result a "toss-up"? 2. How strong is the evidence used in the analysis? 3. Could uncertainty in the evidence change the results? III. Will the Results Help Me In My Patient Care? 1. Do the probabilities fit my patients clinical features? 2. Do the utilities reflect my patients values? References: JAMA 1995; 273: , JAMA 1995; 273:

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