Traumatic Brain Injury

Transcription

1

2 Joe s Story The National Football League (NFL) Hall of Fame quarterback, known as Broadway Joe for his dazzling performance on the field and largerthan-life persona, is now working to make his name synonymous with cutting-edge clinical research, hope and healing for those living with traumatic brain injury. The Joe Namath Neurological Research Center at Jupiter Medical Center holds promise not just for athletes facing neurological issues as a result of grueling competition, but also for military veterans, car accident victims, stroke patients and others suffering from the effects of TBI. On behalf of these people, Joe is determined to find a treatment that works. Joe made Jupiter, Florida, his adopted hometown more than 20 years ago. In 2012, he approached Dr. Lee Fox, Chief of Radiology at Jupiter Medical Center, about traumatic brain injury. Dr. Fox knew a colleague at the medical center who ran a Hyperbaric Oxygen Therapy (HBOT) program for wound care. He heard that the treatments were beginning to be tested for patients with injuries and disease of the brain linked to head trauma. After extensive neurological examination and cognitive tests, it was revealed that Joe was suffering from traumatic brain injury, so he decided to undergo HBOT at Jupiter Medical Center. Dr. Fox conducted SPECT scans and found areas of reduced blood flow in Joe s brain. Dr. Barry Miskin, Chief of Surgery and Co-Director of Hyperbarics, designed a customized regimen of HBOT treatments. The result was Joe s brain showed signs of recovery and new neurologic activity. After one year, Joe was retested, and not only did the benefits of his treatment remain, there was no regression.

3 My thinking is much clearer. Finding the right words has become easier and I remember events with more clarity. One of the great results is that my sleep has improved; I sleep more soundly and have vivid dreams. I now have more energy and strength I feel great! Joe Namath

4 Traumatic Brain Injury Traumatic brain injury (TBI) is one of the leading, undiagnosed brain injuries in the United States. Victims experience symptoms of confusion, loss of memory, slurred speech and seizures. Those living with TBI struggle with its devastating effects for days, months, years or even for the rest of their lives. Regardless of age, anyone can suffer a detrimental brain injury, including professional athletes, motorcyclists, children involved in team sports, military personnel and even senior citizens. The scope of traumatic brain injury is far-reaching and the effects are substantial. TBI occurs when a sudden physical assault on the head causes damage to the brain. The damage can be focal, confined to one part of the brain, or diffuse, involving more than one area of the brain. An estimated 1.7 million people sustain a traumatic brain injury annually in the United States. While 52,000 people die, 275,000 are hospitalized and 1.4 million (nearly 80%) are treated and released from an emergency department. Traumatic brain injury is a contributing factor to nearly a third (30.5%) of all injury-related deaths in the United States. The Centers for Disease Control and Prevention estimate the following: There were 2.5 million incidents of TBI in In 2010, TBI contributed to the deaths of more than 5,000 people. TBI-related emergency department visits increased by 70% from 2001 to ,000 children were treated for TBI that resulted from recreational or sporting activities in A vast number of articles and research studies have been published about the debilitating effects of traumatic brain injury. One theme is consistent there is a major epidemic occurring relating to TBI, however, few treatment options are available. Causes of TBI * 40% Falls 16% Sports Related (being struck by or against an object or person) 16% 40% 14% Motor Vehicle Traffic Incidents 11% Assaults 11% 19% Other (including military combatrelated injuries) * Source: Centers for Disease Control and Prevention (CDC), National Center for Injury Prevention and Control. Guide to Writing About Traumatic Brain Injury in News and Social Media. Atlanta (GA): Centers for Disease Control and Prevention; % 19%

5 Hyperbaric Oxygen Therapy (HBOT) Research at Jupiter Medical Center In 2014, Jupiter Medical Center received FDA approval to open a clinical research trial that aims to combat the devastating effects of TBI. Under the leadership of Co-Medical Directors Barry Miskin, MD, Principal Investigator, and Lee Fox, MD, Sub-Investigator, the clinical trial is a way to determine if hyperbaric oxygenation could be a leading-edge treatment option for brain injury patients. Over the past decade, there have been clinical studies undertaken to evaluate the use of HBOT in the treatment of TBI. The research at Jupiter Medical Center is designed to test the overarching hypothesis that patients with traumatic brain injury treated with HBOT will show improvement in function and an increased blood flow, as evidenced by a single-photon emission computed tomography (SPECT) scan. Improvement is evidenced by an increased number of pixels on SPECT scans and increased brain metabolism. Improvement may also be identified via cognitive assessments administered by the Jupiter Medical Center Research Department. Jupiter Medical Center has a long-established HBOT program on the hospital campus that utilizes a Monoplace, the largest, single-person pure oxygen chamber available. The program is supervised by a trained and experienced HBOT team of physicians and nurses.

6 Research Protocol Clinical Trial JMC-TBI-001 Under the guidance of the Food and Drug Administration (FDA), Jupiter Medical Center s new clinical trial will test the use of HBOT to determine if oxygenation can stimulate the healing process of brain injuries. The research team will carefully screen each patient for preexisting characteristics and administer HBOT using a highly standardized protocol. To be eligible for the trial, patients must have experienced brain injury, including loss of consciousness. The protocol includes patients receiving a total of 40 to 120 HBOT treatments based on the severity of their brain injury. These treatments are intense, with 1.5 ATA (atmospheres absolute) administered five times per week. Phases I and II of the clinical trial will include 100 patients to establish efficacy through data. Phase III will take place upon successful completion of Phases I and II. This trial will be conducted nationally with 1,000 patients, and it will incorporate changes learned in the previous trials to provide a greater statistical significance of efficacy. This larger trial will include partners such as universities and hospitals throughout the country. Impact Jupiter Medical Center is confident in the success of its mission to become a leader in the treatment of head trauma by developing scientifically proven methods to heal the brain, and also reverse the devastating effects of traumatic brain injury for the benefit of patients and their families. TBI is widely considered to be the most damaging condition to the human body, and the most misunderstood. With the knowledge that even a few exposures to HBOT might contribute to brain injury recovery, we are obligated to research this age-old technology as an effective treatment for the 21st century. The goal of this FDA-approved clinical trial is to determine if HBOT can have a significant impact on reversing the damage from head trauma, so that this treatment can become standard practice for patients suffering from TBI.

7 SPECT Scans Before Hyperbaric Oxygen Therapy SPECT Scans After Hyperbaric Oxygen Therapy Join Joe s Mission and Donate Today Today at the Joe Namath Neurological Research Center, you can help us fund this important research that explores Hyperbaric Oxygen Therapy as a treatment for debilitating traumatic brain injury. Through your generous donation, you can enable us to provide important answers and, more importantly, hope to those affected by head trauma.

8 Delivering Hope Through Research 1210 S. Old Dixie Hwy. Building East 1002 Jupiter, Florida NamathNeuroCenter.com JMCFoundation.com JupiterMed.com