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1 NAME Kastner, Sabine BIOGRAPHICAL SKETCH Provide the following information for the Senior/key personnel and other significant contributors. Follow this format for each person. DO NOT EXCEED FOUR PAGES. era COMMONS USER NAME (credential, e.g., agency login) skastner POSITION TITLE Professor of Psychology & Neuroscience EDUCATION/TRAINING (Begin with baccalaureate or other initial professional education, such as nursing, include postdoctoral training and residency training if applicable.) DEGREE INSTITUTION AND LOCATION MM/YY FIELD OF STUDY (if applicable) Georg-August University, Gottingen, Germany BA 06/85 History & Philosophy Heinrich-Heine University, Dusseldorf, Germany MD 12/93 Medicine Georg-August University, Gottingen, Germany MPI for Biophysical Chemistry, Gottingen National Institute of Mental Health, Bethesda, MD PhD Postdoc Postdoc 01/94 01/96 08/00 Neurophysiology Monkey physiology Functional brain imaging Citizenship: United States, Germany/European Union A. Personal Statement The goal of my research program is to better understand how large-scale networks operate during cognition. We use the visual attention network as a model network. Our work is guided by the questions how large-scale networks set up efficient communication and which neural code is used in different network nodes to drive behavior. We study these issues in two primate brain models, the human and the macaque monkey, using an integrated and complimentary methods approach of invasive electrophysiology (Electrocorticography in human epilepsy patients [together with Bob Knight, UC Berkeley, and Josef Parvizi, Stanford] and simultaneous multi-site recordings in monkeys) with several brain imaging modalities (functional magnetic resonance imaging, diffusion tensor imaging). Our studies in the two primate brain models are done in comparison that is afforded by tasks showing an identical behavioral pattern. Additional lines of research in the lab include the neural basis of attentional selection from natural scenes, the functional parcellation of the human parietal cortex, and the neural basis of object perception (including studies with patients suffering from object agnosia and amnesia together with Marlene Behrmann, Carnegie Mellon). B. Positions and Honors Positions and Employment 2012-present Visiting Scientist, Helen Wills Neuroscience Institute, UC Berkeley 2009-present Professor of Psychology & Neuroscience, Princeton University 2005-present Scientific Director, Neuroimaging Facility, Princeton University Associate Professor of Psychology & Neuroscience, Princeton University Assistant Professor of Psychology, Princeton University Visiting Research Associate, National Institute of Mental Health (Drs. L.G. Ungerleider & R. Desimone) 1996 Lecturer, Dept. of Psychiatry, Medical School, University of Gottingen, Germany Postdoctoral Research Fellow, MPI for Biophysical Chemistry, Gottingen/Germany (Drs. H.C. Nothdurft & I.N. Pigarev) PhD student, Max-Planck-Institute for Biophysical Chemistry, Gottingen/Germany (Dr. O.D. Creutzfeldt)

2 Other professional activities Senior Editor, Journal of Neuroscience, 2009 present Reviewing Editor, Journal of Neuroscience, Associate Editor, Journal of Neuroscience, Section Editor (Perception), Neuropsychologia, Handling Editor, NeuroImage, Section Editor (Attention), The Cognitive Neurosciences V (MIT Press, 2014) Editor, The Handbook of Attention (with AC Nobre) (Oxford University Press, 2014) Other editorial board memberships: Cognitive Neuroscience, Brain Topography, Frontiers in Neuroscience, Neuropsychologia, NeuroForum Member, Faculty of 1000, present Member, NIH study section Central Visual Processing (CVP/SPC), Member, NINDS Director s Advisory Panel (Basic Research), 2008 Ad hoc member for > 15 study sections, special emphasis panels since 2004 NSF Cognitive Neuroscience review panel, 2005, 2006, 2011 Honors Distinguished Fellow, Sage Center for the Study of the Mind, Santa Barbara, 2014 Fellow, American Psychological Society, 2010 Young Investigator Award, Cognitive Neuroscience Society, 2005 John McLean Jr., Presidential University Preceptorship, Princeton University, Fellows Award for Research Excellence, National Institutes of Health, 1999 & 2000 Fellow of the German National Scholarship Foundation, C. Selected Peer-Reviewed Publications (from a total of >100 publications) 1. Szczepanski SM, Kastner S (2013): Shifting attentional priorities: Control of spatial attention through hemispheric competition. J. Neurosci. 33: Fiebelkorn IC, Saalmann YB, Kastner S (2013): Sustained spatial selection leads to an interplay of periodic behavioral effects defined by object boundaries. Current Biology 23: Szczepanski SM, Douglas MM, Pinsk MA, Kastner S, Saalmann YB (2013): Fronto-parietal pathways to flexibly specify attentional priorities in different reference frames. Proc. Natl. Acad. Sci. 110: Saalmann YB, Pinsk MA, Wang L, Li X, Kastner S (2012): Pulvinar regulates information transmission between cortical areas according to attentional demands. Science 337: Wang L, Saalmann YB, Pinsk MA, Arcaro MJ, Kastner S (2012): Electrophysiological low-frequency coherence and cross-frequency coupling contributes to BOLD connectivity. Neuron 76, Seidl KM, Peelen MV, Kastner S (2012): Neural evidence for distracter suppression during visual search in real-world scenes. J. Neurosci. 32, Saalmann Y, Kastner S (2011): Cognitive and perceptual functions of the thalamus. Neuron 71: Konen CS, Behrmann M, Nishimura M, Kastner S (2011). The functional neuroanatomy of visual agnosia: A case study. Neuron 71: Peelen MV, Kastner S (2011). A neural basis for naturalistic search in human extrastriate cortex. Proc.Natl. Acad. Sci. 108: McMains SA, Kastner S (2011): Interactions of top-down and bottom-up mechanisms in biasing competition in human visual cortex. J. Neurosci. 31: Arcaro MJ, Pinsk MA, Li X, Kastner S (2011): Visuotopic organization of macaque posterior parietal cortex: An fmri study. J. Neurosci. 31:

3 12. Szczepanski SM, Konen CS, Kastner S (2010): Mechanisms of spatial attention control in frontal and parietal cortex. J. Neurosci. 30: Schneider KA, Kastner S (2009): Effects of sustained spatial attention in the human lateral geniculate nucleus and superior colliculus. J. Neurosci. 29: Arcaro M, McMains SA, Kastner S (2009): Retinotopic organization of human ventral visual cortex. J. Neurosci. 29: Saalmann Y, Kastner S (2009): Gain control in the visual thalamus during perception and cognition. Curr. Opinion Neurobiol. 19: Silver M, Kastner S (2009): Topographic maps in human frontal and parietal cortex. Trends in Cog. Neurosci. 13: Peelen MV, Fei-fei Li, Kastner S (2009). Neural basis of rapid scene categorization. Nature 460: Konen CS, Kastner S (2008a). Two hierarchically organized neural systems for object information in human visual cortex. Nature Neurosci. 11: Konen CS, Kastner S (2008b): Representation of eye movements and stimulus motion in topographically organized areas of human PPC. J. Neurosci. 28: Pinsk MA, DeSimone K, Moore T, Gross CG, Kastner S (2005): Representations of faces and body parts in macaque temporal cortex: an fmri study. Proc. Natl. Acad. Sci. 102: Beck DM, Kastner S (2005). Stimulus context modulates competition in human extrastriate cortex. Nature Neurosci. 8: Wunderlich K, Schneider KA, Kastner S (2005): Neural correlates of binocular rivalry in the human LGN. Nature Neurosci. 8: Schneider KA, Richter M, Kastner S (2004). Retinotopic organization and functional subdivisions of the human lateral geniculate nucleus: A high-resolution fmri study. J. Neurosci. 24: O Connor DH, Fukui MM, Pinsk MA, Kastner S (2002). Attention modulates responses in the human lateral geniculate nucleus. Nature Neurosci. 5: Kastner S, Ungerleider LG (2000). Mechanisms of visual attention in the human cortex. Ann. Rev. Neurosci. 23, Kastner S, Pinsk MA, De Weerd P, Desimone R, Ungerleider LG (1999). Increased activity in human visual cortex during directed attention in the absence of visual stimulation. Neuron 22: Kastner S, DeWeerd P, Desimone R, Ungerleider LG (1998). Mechanisms of directed attention in ventral extrastriate cortex as revealed by functional MRI. Science 282: D. Research Support Ongoing Research Support 1RO1-EY Kastner (PI) 09/01/12 08/31/16 NIH-NEI Functions of the thalamus in perception and cognition. This project aims to explore the role of the macaque pulvinar in attentional selection using physiology methods in monkeys trained to perform an attention task. BCS Kastner (PI) 10/01/13 09/30/16 NSF Attentional selection from natural scenes. This project aims to explore the neural basis of selecting object information from natural scenes in the human brain using a combination of behavioral, transcranial magnetic stimulation and functional magnetic resonance imaging studies.

4 1R21-EY02565 Kastner (PI) 06/01/14 05/31/16 (pending) NIH-NEI Attention network dynamics in the primate brain. This project aims to compare attentional mechanisms across primate species by using electrocorticography, single-cell and local field potential recordings in human epilepsy patients and macaques. Completed research support (during the last three years): 5RO1-MH64043 Kastner (PI) 06/01/02 12/31/13 NIH-NIMH Neural basis of visual attention. This project aims to explore neural mechanisms underlying visual attention in the human brain using functional magnetic resonance imaging (fmri). BCS Kastner (PI) 10/01/10 09/30/13 NSF Representation of object information in the primate brain. This project aims to explore the representation of object information in the dorsal pathway relative to those of the ventral pathway in healthy subjects, in nonhuman primates, and in patients with lesions of the ventral pathway using fmri and behavioral measures. CBIR11PIL026 Pinsk (PI) 06/01/11 05/31/13 NJCBIR (New Jersey Commission on Brain Injury Research) Cortical lesion effects on white matter connectivity: DTI of the macaque. This project seeks to establish monkey diffusion tensor imaging methods in order to examine the macaque attention network, and to explore changes in network connectivity in a longitudinal lesion model. Role: Co-PI E. INVITED PRESENTATIONS & CHAIRS* (last 6 years) *Note that I limit travel to 8-10 talks per year due to family responsibilities. Symosium on Electrocorticography, Society for Neuroscience, Washington, D.C., 2014 Donders Lecture, Donders Institute, Nijmegen 2014 Gordon Research Conference, Newry, ME, 2014 Neuroimaging Program, Medical College Wiscon, Madison, WI, 2014 Neuroscience Program, University of Kentucky, Louisville, 2014 Neuroscience Program, Harvard University, Cambridge, MA, 2014 Vision Seminar, Department of Psychology, Harvard University, Cambridge, MA, 2014 Cognitive Neuroscience Summer Institute, Lake Tahoe, CA, 2013 Workshop, Oxford University, Oxford, 2013 Attention symposium, CNS, San Francisco, CA, 2013 Neuroscience program, University of Rochester, 2013 Department of Neuroscience, Caltech, Pasadena, CA, 2013 Neuroscience program, Duke University, NC, 2013 Key Note Speaker, ASSC, San Diego, CA, 2013 Department of Psychology, Ohio State University, Columbus, OH, 2013 Key Note Speaker, Neuroscience Symposium, University of NC, Chapelhill, NC, 2013 Baylor Medical College, Houston, TX, 2012 Washington University, St. Louis, 2012 Georgetown University, Washington D.C., 2012 Johns Hopkins University, Baltimore, MD, 2012 UC Davis, Davis, CA, 2012

5 Vision Science Society (Symposium), Naples, FL, 2012 Society for Neuroscience (Chair), New Orleans, LO, 2012 University of Tuebingen (Workshop), Tuebingen, Germany, 2012 University of Montreal, Montreal, CA, 2012 MBI Cognitive Neuroscience Workshop, Columbus, OH, 2012 University of Western Ontario, London, CA, 2011 Xiangshang Conference, Hongkong, CH, 2011 Workshop on concepts, actions and objects, Rovereto, IT, 2011 Human Brain Mapping, Quebec, CA, 2011 Department of Neuroscience, Rockefeller University, NYC, 2011 Department of Psychology, Brandeis University, Boston, 2011 Florida Atlantic University, Boca Raton, FL, 2011 Mini-Symposium (Chair & organizer), SfN, Washington D.C., 2011 University of Virginia, Richmond, VA, 2011 Department of Psychology, University of Toronto, Toronto, 2010 Neuroscience Program, Brown University, Providence, RI, 2010 Workshop on selective attention, Hebrew University, Jerusalem, 2010 Columbia University, New York City, NY, 2010 NYU, New York City, NY, 2010 Attention symposium, Human Brain Mapping Conference, Barcelona, 2010 Gordon Research Conference, Waterville, NH, 2010 Neuroscience Program, University of Chicago, IL, 2010 Society for Neuroscience, San Diego, CA (Chair), 2010 Department of Neurobiology, UT Houston, TX, 2010 Yale University, New Haven, CT, 2009 Plasma Physics Laboratory, Princeton University, Princeton, NJ, 2009 Stanford University, Palo Alto, CA, 2009 Carnegie Mellon University, Pittsburgh, PA, 2009 Duke University, Durham-Raleigh, NC, 2009 University of Washington, Seattle, WA, 2009 Cosyne, Salt Lake City, 2008 Dept. of Psychology, Vanderbilt University, 2008 EBA, Boston, 2008 Days of Molecular Medicine, Stockholm, 2008 Dept. of Psychology, Rutgers University, 2008 Summer Institute in Cognitive Neuroscience, Lake Tahoe, 2008 Optical Society of America, Rochester, 2008 Society for Neuroscience, Washington (Chair), 2008

35 Gedney Rd

Ryan E.B. Mruczek home address: phone, e-mail, and website: 35 Gedney Rd 401.573.3022 Lawrence, NJ 08648 rmruczek@unr.edu http://wolfweb.unr.edu/~rmruczek/ Academic Employment Research Scientist Department