LEMONS, GUINEA PIGS & SATURDAY NIGHT FEVER
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1 LEMONS, GUINEA PIGS & SATURDAY NIGHT FEVER DE-MYSTIFYING CLINICAL RESEARCH PRESENTED BY TAMMY BEAUDOIN CLINICAL RESEARCH FACILITATOR OCTOBER 13, 2016 WORLD THROMBOSIS DAY Affiliated with Affilié à
2 CLINICAL RESEARCH MAKES ME THINK OF. Needles & all things scary Labs & potions Crazy experiments New drugs & treatments Human guinea pigs 2
3 HISTORICALLY SPEAKING Clinical research has been around for centuries just in a less formal format Every one of us has been impacted by past clinical research initiatives In 1946, the first documented randomized In 1747 The Dr. Nuremberg James Lind trial controlled trial was suspected began that on December the acids in 9, conducted in Tuberculosis lemons 1946, would led effectively by the United treat patients Scurvy in States sailors. 20 Nazi physicians were tried and convicted for Bed their rest alone? Bed rest plus part in brutal human Streptomycin (antibiotic)? experiments at Auschwitz Which had a better outcome? The group that received From this trial, 10 laws Chest to which x-rays were used to assess the citrus fruit, recovered doctors must conform the when TB and monitoring of the quickly the vitamin C was carrying out clinical research patients were showed increased determined to be of developed and are now improvement accepted with antibiotics! benefit! worldwide. 3
4 DID YOU KNOW? Many of the treatments we have in Canada today are available thanks to people like you volunteering to take part in clinical research! Clinical trials have helped develop screening processes and ways to prevent disease altogether! Lifestyle changes such as exercise and diet are often studied in clinical research and lead to people living longer with diseases like cancer, heart disease, etc. A recent study has revealed that exercising can drastically reduce the risk of breast cancer, bowel cancer, heart disease and stroke. 4
5 WHAT IS CLINICAL RESEARCH ANYWAY? Any research conducted with human subjects OR on material of human origin (blood, stem cells, tissues) It is a branch of health care that determines if medications, devices, diagnostic products and treatment plans are safe and effective for humans Sometimes focuses on a specific group of people specific gender, specific illness, specific geographic location It is not always interventional, lots of clinical research is observational! 5
6 MAKING SENSE OF CLINICAL RESEARCH 6
7 Health Canada Regulated Trial Participant Risks Research Ethics Protocol Cohort Case Control Phase I Serious Diagnosis Eligibility Criteria Placebo Randomized Controlled Trial Questionnaires Informed Consent Study Drug Benefits Quality of Life Experiment 7
8 I WANT TO LEARN MORE ABOUT CLINICAL RESEARCH 8
9 WHAT S THE POINT OF ALL OF THIS? Researchers may find The safest options & may learn about side effects if applicable. Which treatment works better. New ways to use treatments we already have available to us. Which groups benefit the most perhaps children or elderly. How to prevent a disease that is common in society. How to identify at risk patients before a disease surfaces. 9
10 WHAT ABOUT ME? WHY SHOULD I PARTICIPATE? Learn about new treatments Try a new treatment Help others in the future Learn more about a disease & prevention Help improve healthcare process Advances health care 10
11 ALWAYS KEEP IN MIND Participation in any type of research is 100% voluntary. You can withdraw at any time. Your decision will not impact your care! 11
12 ALWAYS KEEP IN MIND Ask questions it is your right! Work with your research team, research is a joint effort. If you aren t sure about something or are uncomfortable with something, speak up! 12
13 ALWAYS KEEP IN MIND You will be given a consent form, Take the time to read it. Ask as many questions as you like. If you are unsure about something, tell someone! 13
14 TRUE OR FALSE? I can only participate in clinical research if I m really sick or have been hurt very badly? I will benefit from participating in a clinical trial? The care/services I receive will not be affected if I don t participate in clinical research? The only role I can play in clinical research is as a patient participant? 14
15 CLINICAL RESEARCH AT THE OTTAWA HOSPITAL CIHR IS THE MAJOR FEDERAL AGENCY RESPONSIBLE FOR FUNDING HEALTH RESEARCH IN CANADA INSPIRED BY RESEARCH As a patient, you will be approached and asked to consider hearing about research that is conducted here saying yes means your are open to the idea. More than 600 clinical trials were being conducted at TOH in 2015 More than 15,000 patient volunteers were involved! We are in the top 3 Canadian hospitals to receive funding from the Canadian Institutes of Health Research (CIHR) taxpayer dollars at work! 15
16 CLINICAL RESEARCH AT THE OTTAWA HOSPITAL DRIVEN BY COMPASSION Interacting with patients, hearing what their questions are and trying to answer those questions are the reasons that drive me to do clinical research - Dr. Marc Carrier 16
17 WE AND ARE THIS RECOGNIZED INTERNATIONALLY FOR THIS 17
18 OUR RESEARCH IN THE HEADLINES! 18
19 WE NEED YOUR HELP! We want to hear from you! If you have ever been approached to be part of a research study or clinical trial we need your feedback! 19
20 The song Stayin Alive from the movie Saturday Night Fever is applicable to this presentation! Why? In 2008, a physician-researcher from Chicago determined that this song has 103 beats per minute it is the recommended rate for compressions during CPR!! One other song was identified as having the same beat, but it is less encouraging. Any guesses?? Another One Bites the Dust Research is educational & fun!! 20
21 Thank You! Affiliated with Affilié à 21
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