WILLIAM J. BEUTLER, M.D., FAANS, FACS
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1 WILLIAM J. BEUTLER, M.D., FAANS, FACS Education Premedical The Johns Hopkins University Baltimore, Maryland B.E.S, Biomedical Engineering Medical State University of New York at Buffalo School of Medicine Buffalo, New York POST GRADUATE Georgetown University Hospital Department of Neurosurgery Neurosurgery Residency Atkinson Morley s Hospital London, England Neurosurgery Registrar PRIVATE PRACTICE OTHER POSITIONS Pennsylvania Spine Institute 820 Sir Thomas Court Harrisburg, PA July 2000-present Medical Director of PinnacleHealth Spine Institute October 2010-Present SPINE FELLOWSHIP LICENSURE Orthopedic Spine Fellowship State University of New York Upstate Medical University Syracuse, New York Hanson A. Yuan, M.D. (Director) PA MD043673E
2 Page 2 CERTIFICATION American Board of Neurological Surgery Fellow American College of Surgeons Fellow American Association of Neurological Surgeons NPI #: PROFESSIONAL SOCIETIES PUBLICATIONS American Association of Neurological Surgeons Congress of Neurosurgeons American College of Surgeons Pennsylvania Neurosurgical Society American Medical Association North American Spine Society Pennsylvania Medical Society International Society for Advancement of Spine Surgery (ISASS) Beutler, W.J. Ganglioside Patterns in Chinese Hamster Cells in Culture The Johns Hopkins University Undergraduate Science Bulletin, Vol. 7, No. 2, 3-10, Peterson, R.H.F., Beutler, W.J., Biedler, J.L. Anomalous Ganglioside Composition of Malignant and Actinomycin D-resistant Nonmalignant Chinese Hamster Cells, The Journal of Cell Biology, Vol 79, (part two), 229a, Peterson, R. H. F., Beutler, W.J., Biedler, J.L. Ganglioside Composition in Malignant and Actinomycin D-resistant Nonmalignant Chinese Hamster Cells, Biomedical Pharmacology, Vol. 28, No. 5, , Hirshfeld, A., Beutler, W.J., Seigle, J. Manz, H. Spinal Epidural Compression Secondary to Osteoblastic Metastatic Vertebral Expansion, Neurosurgery, Vol 23, , Frederickson, B.E., Baker, D., Murtland, A.M., Sweeney, C.A., Beutler, W.J. The Natural History of Spondylosis and Spondylolisthesis: 45-year Follow-up, Orthopedics Today. Frederickson, B.E., Baker, D., Murtland, A.M., Sweeney, C.A., Beutler, W.J. The Natural History of Spondylolysis and Spondylolisthesis: 45-year Follow-up, Spine Line, Page 29, September Beutler, W.J., Sweeney, C.A., Connolly, P.J. Recurrent Laryngeal Nerve Injury with Anterior Cervical Spine Surgery: Risk with Laterality of Surgical Approach, Spine, Vol. 26, No. 123, , 2001.
3 Page 3 William J. Beutler, M.D., FAANS, FACS Sagi, H.C., Beutler, W.J., Carroll, E., Connolly, P.J. Airway Complications Associated with Surgery on the Anterior Cervical Spine, Spine, Vol 27, No. 9, , Beutler, W.J., Dunn, Lori, Peppelman, W.C., Radiographic Assessment of Interbody Lumbar Interbody Fusion: The Cage-O-Gram, The Spine Journal, Vol. 2, No. 2S, 28S, Beutler, W.J., Peppelman, W.C., Anterior Lumbar Fusion with Paired-BAK Standard and Paired-BAK Proximity Cages: Subsidence Incidence, Subsidence Factors, and Clinical Outcome, The Spine Journal, Vol. 3, No. 4, , July/August Frederickson, B.E., Baker, D., Murtland, A.M., Sweeney, C.A., Beutler, W.J. The Natural History of Spondylolysis and Spondylolisthesis: 45-year Follow-up, Spine, Vol. 28, No. 10, , Beutler, W.J., Peppelman, W.C. Aesculap Shadow Posterior Segmental Instrumentation System, Spinal Instrumentation: Surgical Techniques. New York: Theime; 2005: (Book Chapter). Malloy, John P., Beutler, William, Peppelman, Harris, Ryan, Slotkin, Eric, Gillette, Jeff, Clinical Outcomes with Porous Tantalum in Lumbar Interbody Fusion, The Spine Journal, September 2009, Vol 10, Issue 9S, Supplement page S147-S148. McConnell, Jeffrey, Marzluf, Joseph, Tomaras, Christopher, Volcan, Ildemaro, Goodrich, Allan, Peppelman, Walter, Beutler, William, Asdorian, Paul L., Baker, Kelly A Clinical Comparison of a Cervical Artifical Disc and Anterior Cervical Discectomy and Fusion in a Prospective Randomized Trial: Two-Year Follow-up, The Spine Journal, October 2009, Vol 9, Issue 10, Supplement, Pages 190S- 191S. Beutler, William, Peppelman, Walter, Reuben, Jeff, Muzumdar, Aditya, Ingalhalikar, Aditya, Bucklen, Brandon, Moldavsky, Mark, Khalil, Saif, A Biomedical Comparison of Integrated vs. Variable Cross-Connectors and Dual-Diameter vs. Single Diameter Screw Constructs at L5-S, The Spine Journal, October 2009, Vol 9, Issue 10, Supplement, Pages 197S- 198S. Beutler, W.J., Peppelman, W.C., Clinical Experience Using Cortoss for Treating Vertebral Compression Fractures with Vertebroplasty and Kyphoplasty. Spine, Volume 35, No. 20, , Andrew L. Clavenna, MD, William J. Beutler, MD, Manasa Gudipally, MS, mark Moldavsky,BS, Saif Khalil, PhD., The Biomechanical Stability of a Novel Spacer with Integrated Plate in Contiguous Two-Level and Three-Level ACDF Models: An In Vitro Cadaveric Study. The Spine Journal, Vol 12, Number 2, (2012) pp Beutler, William J., MD, Clavenna, Andrew L., MD, Gudipally, Manasa, MS, Moldavsky,Mark, BS, Khalil, Saif, PhD., A biomechanical evaluation of a spacer with integrated plate for treating adjacent-level disease in the subaxial cervical spine. The Spine Journal, Vol 12 (2012) Number 7, pp
4 Page 4 Beutler, William J., MD, Peppelman, Walter, Jr.,DO, DiMarco,Luciano, D.O"The da Vinci Robotic Surgical Assisted Anterior Lumbar Interbody Fusion: Technical Development and Case Report", Spine, Volume 28 No. 4 February Vaccaro, Alexander MD, PhD, Beutler, William MD, Peppelman,Walter, DO, Marzluff, Joseph M. MD, Highsmith, Jason MD, Mugglin, Andrew PhD, Demuth, George, MS, Gudipally, Manasa MS, Baker, Kelly J. PhD., Clinical Outcomes With Selectively Constrained SECURE-C Cervical Disc Arthroplasty: Two-Year Results From a Prospective, Randomized, Controlled, Multicenter Investigational Device Exemption Study, Spine, December 2013, Vol 38, Issue 26 pages Gordon, Michael, MD, Peppelman, Walter C, DO, Beutler, William, MD, O Halloran Damien, PhD, Chintakunta, Suresh R., MS, Bucklen, Brandon, PhD., An In Vitro Evaluation of Fracture Reduction Achieved by Inflatable Bone Tamps Under Simulated Physiological Load, J. Spinal Disorder Techniques (pending publication) NATIONAL/INTERNATIONAL PRESENTATIONS Laterality of Surgical Approach, Beutler, W.J., C.A., Connolly, P.J. (Presented to the Cervical Spine Research Society (European), London, England, June 22, 2000). Laterality of Surgical Approach, Beutler, W.J., Sweeney, C.A., Connolly, P.J. (Presented to Cervical Spine Research Society, Charleston, South Carolina, November 30, 2000). Laterality of Surgical Approach, Beutler, W.J., Sweeney, C.A., Connolly, P.J. (Presented to AANS/CNS Section on Disorders of the Spine and Peripheral Nerves, Phoenix, Arizona, February 15, 2001). Laterality of Surgical Approach, Beutler, W.J., Sweeney, C.A., Connolly, P.J. (Presented to American Association of Neurological Surgeons, Toronto, Ontario, Canada, April 23, 2001). The Natural History of Spondylolysis and Spondylolisthesis: 45-year Follow-up, Frederickson, B.E., Baker, D., Murtland, A.M., Sweeney, C.A., Beutler, W.J. (Presented to Scoliosis Research Society, Sydney, Australia, October 19, 2000). The Natural History of Spondylolysis and Spondylolisthesis: 45-year Follow-up, Frederickson, B.E., Baker, D., Murtland, A.M., Sweeney, C.A., Beutler, W.J. (Presented to North American Spine Society, New Orleans, Louisiana, October 26, 2000).
5 Page 5 William J. Beutler, M.D, FAANS, FACS Anterior Lumbar Interbody Fusion with paired BAK Proximity and paired BAK Standard cages: Subsidence incidence and Clinical outcome, Beutler, W.J., Peppelman, W.C. (Oral poster presentation to the AANS/CNS Section on Disorders of the Spine and Peripheral Nerves, Phoenix, Arizona, February 15, 2001). Anterior Lumbar Interbody Fusion with paired BAK Proximity and paired BAK Standard cages: Subsidence incidence and Clinical outcome, Beutler, W.J., Peppelman, W.C. (Poster presentation North American Spine Society, November 2001). Radiographic Assessment of Interbody Lumbar Interbody Fusion: The Cage-O-Gram, Beutler, W.J., Dunn, L., Peppelman, W.C., Wolf, S.B. (Presented to North American Spine Society, November 3, 2001). Airway Complications Associated with Surgery on the Anterior Cervical Spine, Sagi, H.C., Beutler, W.J., Carroll, E., P.J. ( Presented to Cervical Spine Research Society, December 2001). Outcome Analysis of First Generation Unicortical Cervical Plate Fixation, Bennett, M.J., Beutler, W.J., Connolly, P.J., (Submitted to Cervical Spine Research Society and North American Spine Society). The Natural History of Spondylolysis and Spondylolisthesis: 45-year Follow-up, Frederickson, B.E., Baker D., Murtland, A.M., Sweeney, C.A., Beutler, W.J. (Presented at the Congress of Neurological Surgeons, Philadelphia, PA, September 2002). Posterior Lumbar Interbody Fusion with Posterior-oblique Lumbar Arthrodesis (POLAR): Indications and Outcome, Beutler, W.J., Peppelman, W.C. (Presented at the International Conference on Spinal Surgery, Beijing, China, October 2002). Anterior Lumbar Interbody Fusion with paired BAK Proximity and paired BAK Standard cages: Subsidence incidence and Clinical outcome, Beutler, W.J., Peppelman, W.C. (Presented at the International Conference on Spinal Surgery, Beijing, China, October 2002). Anterior Lumbar Interbody Fusion with paired BAK Proximity and paired BAK Standard cages: Subsidence incidence and Clinical outcome, Beutler, W.J., Peppelman, W.C. (Presented at the International Conference on Spinal Surgery, Chongqing, China, October 2002). Assessment of Lumbar Interbody Fusion Status by Discogram Technique: Rate of Concordant Pain Response, Determination of Pseudoarthrosis and Results of Revision Surgery: Beutler, W.J., Dunn, L., Peppelman, W.C., Petrizzo, A., (Presented to the North American Spine Society, Montreal, Canada, October 2002).
6 Page 6 Assessment of Lumbar Interbody Fusion with Posterior-Oblique Lumbar Arthrodesis (POLAR): Indications and Outcome, Beutler, W.J., Peppelman, W.C., (Presented to Pinnacle Health Hospitals, Medical Education Day, Harrisburg, Pennsylvania, February 2003). Assessment of Lumbar Interbody Fusion Status by Discogram Technique: Rate of Concordant Pain Response, Determination of Pseudoarthrosis and Results of Revision Surgery: Beutler, W.J., Dunn, L., Peppelman, W.C., Petrizzo, A., (Presented to Pinnacle Health Hospitals, Medical Education Day, Harrisburg, Pennsylvania, February 2003.) Laterality of Surgical Approach, Beutler, W.J., Sweeney, C.A., Connolly, P.J. (Presented to Pinnacle Health Hospitals, Medical Education Day, Harrisburg, Pennsylvania, February 2003). Laterality of Surgical Approach, Beutler, W.J., Sweeney, C.A., Connolly, P.J. (Presented to the AANS/CNS Section on Disorders of the Spine and Peripheral Nerves, 19 th Annual Meeting, Tampa, Florida, March 2003). Posterior Oblique and Transforaminal Lumbar Arthrodesis, Beutler, W.J., Peppelman, W.C. (Presented to the American College of Spine Surgery, 2003 Annual Meeting & Spine Surgery Review Course, Naples, Florida, September 2003). Recurrent laryngeal nerve injury with Anterior Cervical Spine Surgery: A prospective randomized study of risk with Laterality of Surgical Approach, Perri B., Beutler, W.J., (Poster presentation to the Cervical Spine Research Society, 31 st Annual Meeting, Scottsdale, Arizona, December 2003). Recurrent laryngeal nerve injury with Anterior Cervical Spine Surgery: A prospective randomized study of risk with Laterality of Surgical Approach, Perri B., Beutler, W.J., (Presented to the Congress of Neurological Surgeons, 54 th Annual Meeting, San Francisco, California, October 2004). Recurrent laryngeal nerve injury with Anterior Cervical Spine Surgery: A prospective randomized study of risk with Laterality of Surgical Approach, Perri B., Beutler, W.J., (Presented to the North American Spine Society, 19 th Annual Meeting, Chicago, Illinois, October 2004). S4 Spinal System: Clinical Use, Beutler, W.J., (Presented to Japanese surgeons, Okinawa, Japan, March 2005). S4 System Presentation and System Development, Beutler, W.J., (Presented in Okinawa, Japan, March 2005).
7 Page 7 Clinical Experience Using a Novel Bio-Ceramic for Treating Vertebral Compression Fractures in Vertebroplasty and Kyphoplasty; Report on the First 40 Patient s Bae, H., Maurer, P., Peppelman, W., Beutler, W., Linovitz, R., Westerlund E., Peppers, T., Lieberman, I., Kim, C., Girardi F., (Presented at IMAST, July 2005). A Prospective, Randomized Evaluation of Low Profile versus Standard Profile Pedicle Screw Constructs: Does size really matter? Beutler, W.J., Peppelman, W.C., (Presented as a posterior presentation at World Spine III, Rio de Janeiro, Brazil, August 2005). Clinical Experience Using a Novel Bio-Ceramic For Treating Vertebral Compression Fractures in Vertebroplasty and Kyphoplasty; Report on the First 40 Patient s, Bae, H., Maurer, P., Peppelman, W., Beutler, W., Linovitz, R., Westerlund E., Peppers, T., Lieberman, I., Kim, c., Girardi, F., (Presented at the North American Spine Society, Philadelphia, Pennsylvania, September 2005). Anterior Cervical Fusion with Variable Angle Screw Instrumentation: Selective Subsidence and Lordosis Progression, Cralwey, C., Beutler, W., Peppelman, W., Espenshade, M., (Presented at the North American Spine Society, Philadelphia, Pennsylvania, September 2005). Two Year Clinical Outcomes of a Cervical Artificial Disc Compared to Anterior Cervical Discectomy and Fusion in a Prospective Randomized Study, Marluff J., Highsmith J., Tomaras C., Morrison T., Steuer M., Volcan I., Goodrich A., Peppelman W., Beutler W., Wolfe S., (Presented at the North American Spine Society, Toronto, Canada, October 2008). Radiographic Outcomes Following Cervical Disco Arthroplasty Compared to Anterior Cervical Discectomy and Fusion in a Prospective Randomized Study, Marzluff J., Highsmith J., Tomaras C., Morrison T., Steuer M., Volcan I., Goodrich A., Peppelman W., Beutler W., Wolfe S., (Presented at the North American Spine Society, Toronto, Canada October 2008). A Prospective Study of Tantalum Trabecular Metal in Lumbar Interbody Fusion Beutler, W.J., Peppelman, W.C., (Presented at the American Academy of Orthopedic Surgeons, Boca Rotan, Florida, September 2008). A Clinical Comparison of a Cervical Artificial Disc and Anterior Cervical Discectomy and Fusion in a Prospective Randomized Trial: Two-Year Follow-Up, McConnell, J., Marzluff J., Tomaras C., Volcan I., Goodrich A., Peppelman W.C., Beutler W.J., Asdorourian P.L., Baker K., (Presented at the North American spine Society, San Francisco, CA, November 2009). A Biomechanical Comparison of Integrated vs. Variable Cross-Connectors and Dual- Diameter vs. Single Diameter Screw Constructs at L5-S1, Beutler W.J., Peppelman W.C., Reuben J., Muzumadar A., Ingalhalikar A., Bucklen B., Moldavsky M., Khalil S., (Presented at the North American Spine Society, San Francisco, CA, November 2009).
8 Page 8 William J. Beutler, M.D., FAANS, FACS Does a Combination of Integrated Rods with Dual Outer Diameter Pedicle Screws Provide Increased Stability and Fixation at the Lumbosacral Junction? : An in vitro study, William J. Beutler, M.D., Walter Peppelman, Jr., D.O., Jeff Reuben, M.D., Aditya Muzumdar, MS, Adity Ingalhalikar, MS, Brandon Bucklen, PhD, Mark Moldavsky, BS, Saif Khalil, PhD, (E-Poster presented at NASS 2009). An In-Vitro Biomechanical Study Evaluating a Spacer with Integrated Plate for Treating Adjacent Level Disease in the Subaxial Cervical Spine, Andrew Clavenna, M.D., William J. Beutler, M.D., Manasa Gudipally, MD, Mark Moldavsky, BS, Saif Khalil, PhD. (Poster presentation at CNS, San Francisco 2010.) Clinical Outcomes and Porous Tantalum in Lumbar Interbody Fusion, John P. Malloy, IV, D.O., William Beutler, M.D., Walter Peppelman, D.O., Ryan Harris, D.O., Eric Slotkin, D.O., Jeff Gillette, D.O., (Presented at the North American Spine Society, Orlando, Florida October 2010). A Prospective, Randomized, Pivotal Study of the Secure-C Cervical Artificial Disc: Two Year Outcomes, W. Beutler, W. Peppelman, J.M. Marzluff, C. Tomaras, I. Volcan, P. Asdourian, J. Mcconnell, K. Baker, J. Myer, (Presented at SAS April 2011, Las Vegas, NV) Radiographic Outcomes Following Cervical Disc Arthroplasty Compared to Anterior Cervical Discectomy and Fusion in a Prospective Randomized Study, W. Peppelman, W. Beutler, J. McConnell, J. Mcconnell, K. Baker, J. Myer, (Presented at SAS April 2011, Las Vegas, NV). SECURE-C Cervical Artificial Disc: Outcomes from a Prospective, Randomized IDE Study at 24 months and Beyond, W. Beutler, W.C. Peppelman, J.M. Marzluff, C. Tomaras, I. Volcan, P. Asdourian, J. Myer, K. Baker, (Presented at ISASS Annual Meeting, Barcelona, Spain, March 2012). Novel Anterior versus Combined Anterior-Posterior Instrumentation Technique for a Simulated Bilateral Cervical Facet Dislocation: An In-Vitro Human Cadaver Study, W. Beutler, W. Peppelman, M. Gudipally, M. Adu-Lartey, J. Brooks, P. Niknam, S. Khalil, (Presented at ISASS Annual Meeting, Barcelona, Spain, Mach 2012). Cervical Arthroplasty with the SECURE-C Cervical Artificial Disc: A Superior Option, William Beutler, MD, Walter C. Peppelman, Jr., D.O., Joseph Marzluff, M.D., Christopher Tomaras, M.D., Ildemaro Volcan, M.D., Paul Asdourian, M.D., Jacqueline Myer, Kelly Baker, PhD. (Presented at North American Spine Society s 27 th Annual Meeting, Dallas, Texas, October 2012).
9 Page 9 The Role of Cervical Arthroplasty in Reducing the Incidence of Secondary Surgery, William Beutler, M.D., Walter C. Peppelman, Jr., D.O., James Lindley, Jeffrey McConnell, M.D., Jacqueline Myer, Kelly Baker PhD. (Presented at North American Spine Society s 27 th Annual Meeting, Dallas, Texas, October 2012). The da Vinci Robotic Surgical Assisted Anterior Lumbar Interbody Fusion: Technical Development and Case Report William Beutler, M.D., Walter C. Peppelman, Jr., D.O., Luciano DiMarco, D.O. (Poster presented at ISASS 2013, Vancouver, BC). SECURE-C Cervical Artificial Disc IDE Clinical Trial: Outcomes at Two and Five Year, W.J. Beutler, W.C. Peppelman, J. Marzluff, C. Tomaras, I. Volcan, P. Asdourian, K. Baker, J. Myer. (Presented at ISASS 2013, Vancouver, BC). Does Preservation of Motion in the Cervical Spine after Treatment with the SECURE-C Artificial Disc Result in Fewer Subsequent Surgical Interventions? J. McConnell, W.J. Beutler, W.C. Peppelman, J. Marzluff, J. Highsmith, J. Lindley, K. Baker, J. Myer. (Poster presented at ISASS 2013, Vancouver, BC). An in vitro Evaluation of Fracture Reduction Achieved by Two Inflatable Balloon Tamps under Stimulated Physiological Load, M. Gordon, W. Beutler, W.C. Peppelman, S. R. Chinthakunta, D.O. Holloran, (Poster presented at ISASS 2013, Vancouver, BC). The Incidence of Surgical Treatment at Adjacent Segments after Anterior Cervical Discectomy and Fusion or Cervical Arthroplasty, W. Beutler, W. Peppelman, J. McConnell, J. Lindley, C. Tomaras, K. Baker, J. Myer, D. McKee. (Presented at ISASS 2014, Miami, FL). The Incidence of Symptomatic Adjacent Segment Disease Requiring Treatment: Cervical Arthroplasty Versus ACDF, William Beutler, MD, FACS; Jeffrey R. McConnell, MD; James G. Lindley, MD and Jacqueline Myer ( E-poster at NASS 2014, San Francisco, CA). Long Term Experience with Cervical Arthroplasty: Six and Seven Year Outcomes from the Secure-C Cervical Artificial Disc Study, W. Beutler,, J. Highsmith, I. Vocan, P. Asdourian, J., McDonnell, K. Baker, J. Myer (Presented at ISASS 2015, San Diego, CA). SECURE-C Cervical Artificial Disc: A Proven Superior Option, W. Beutler, I. Volcan, P. Asdourian, K. Baker, J. Myer (Presented at ISASS 2016, Las Vegas, Nevada). Superiority of Cervical Arthroplasty vs. ACDF: Seven Year Outcomes from the Evaluation of the SECURE-C Cervical Artificial Disc, J. Myer, W Beutler (Presented at NASS 2016, Boston, MA). The Impact of Time on Patients Perception of Cervical Arthroplasty with SECURE-C: An Analysis of Patient-reported Outcomes at Two and Seven Years Postoperative, W. Beutler,I. Volcan, P. Asdourian, J. Myer, K. Baker (Presented at ISASS 2017, Boca Raton, FL).
10 Page 10 ON-PEER REVIEWED ARTICLES Beutler, W.J., Breaking News on Backs, Today s Harrisburg Woman News Magazine, Page 15, July Beutler, W.J., New Hope with Kyphoplasty, Lifestyles & Wellness, Senior News, Page 12, September Reviewer for The Spine Journal 2006 Reviewer for the Spine Arthroplasty Society Journal 2007 to present AWARDS Best Attending Presentation, Stereotactic Brain Biopsy Polyclinic Medical Center Medical Education Day April 4, 1991 Research Traveling Fellowship Award North American Spine Society October 27, 2000 Robert L. Green Orthopedic Excellence Aware June 2001 Best Attending Presentation, Kyphoplasty Medical Education Day March 29, 2001 Best Surgical Attending Presentation, Artificial Lumbar & Cervical Disc: Current Status & Clinical Results April 21, 2006 Best Attending Presentation, Cervical Fusion vs. Artificial Cervical Disc Beutler, W.J., Peppelman; W.C. Medical Education Day April 16, 2008 JTE Service Pillar Award Highest Industry HCAHPS Inpatient Scores 2010
11 Page 11 Best Attending Physician Presentation Development of the da Vinci Robotic Assisted Anterior Lumbar Interbody Fusion Medical Education Day April 2012 Pinnacle Health Physician Recognition Award Recognizing Clinical Quality and Patient Experience Awarded June 2017 Revised 01/24/2018
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