CURRICULUM VITAE. NAME: Douglas Paddon-Jones, Ph.D., FACSM August, 2017

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1 CURRICULUM VITAE NAME: Douglas Paddon-Jones, Ph.D., FACSM August, 2017 PRESENT POSITION: Sheridan Lorenz Distinguished Professor in Aging and Health Department of Nutrition and Metabolism School of Health Professions The University of Texas Medical Branch 301 University Blvd Galveston, Texas USA Office: Admin: Lab: EDUCATION: Post-Doctoral Fellowship Protein Metabolism, Department of Surgery The University of Texas Medical Branch Shriners Hospital for Children. Galveston, Texas. USA Doctor of Philosophy (Ph.D.) Human Movement Studies The University of Queensland. Australia Master of Science (MS) Exercise Physiology Ball State University, Muncie, Indiana. USA 1994 Bachelor of Science with 1 st class Honours (BSc Hons, 1 st Class) Human Movement Studies The University of Queensland. Australia Bachelor of Science (BSc) The University of Queensland. Australia Diploma of Applied Science (Dip.App.Sc) Diagnostic Medical Imaging Queensland University of Technology. Australia ADDITIONAL COURSES AND TRAINING: 2008 University of Texas, TeleCampus (UTTC) Seminar Series, Austin, Tx 2007 Scholar in Education

2 Office of Educational Development, UTMB 2006 Facilitation Skills Workshop Integrated Medical Curriculum, Office of Educational Development 2002 Fellowship in Contrast Enhanced Ultrasound and Skeletal Muscle Microvascular Perfusion University of Virginia, Charlottesville 2000 Tracer Methodology in Biology and Medicine Department of Surgery / Metabolism Unit, UTMB 1996 Certified Strength and Conditioning Specialist (CSCS) National Strength and Conditioning Association. USA 1993 Post-Graduate Elective in Sports Medicine Australian Sports Medicine Federation, Brisbane, Australia Douglas Paddon-Jones 2

3 PROFESSIONAL EXPERIENCE: The University of Texas Medical Branch: Sheridan Lorenz Distinguished Professor in Aging and Health Director, Translational Research in Physical Activity & Functional Recovery Laboratory Co-Leader, Clinical Research Resource Core (CR-RC1). Claude D. Pepper Older Americans Independence Center Professor (with tenure). Department of Nutrition and Metabolism Vice-Chair, Institutional Review Board Associate Professor, Physical Therapy Director of Exercise Studies. General Clinical Research Center Member, Graduate Faculty. Preventative Medicine and Community Health Graduate Program. Graduate School of Biomedical Sciences Curriculum Faculty Member, Division of Rehabilitation Sciences Director, Exercise Metabolism Lab. Shriners Hospital for Children Assistant Professor. Department of Surgery Research Scientist. Surgery and Shriners Hospital for Children Other Professional Experience: Visiting Scholar, Ingestive Behavior Research Center Purdue Univ Adjunct Professor, University of the Sunshine Coast, Australia Strength and Conditioning Coach. Brisbane Bullets, Australian National Basketball League Staff / Locum Radiographer. Private Practice. Queensland, Australia Douglas Paddon-Jones 3

4 COMMITTEE RESPONSIBILITIES: The University of Texas Medical Branch: 2015 Institutional Security and Privacy Compliance Committee Student Grievance and Appeals Committee, SHP Institutional Faculty Grievance Board Institute for Translational Sciences, Scientific Review Committee 2013 Search Committee, UTMB Vice President and CRO Chair, Post Tenure Review Committee, SHP Chair, Institutional Committee on Scientific Integrity Academic Enterprise Space Advisory Committee Postdoctoral Advisory Committee Research Committee, Orthopedics Residency Program Executive Committee, Institutional Review Board Chair, Committee on Scientific Integrity 2007 Scholarship and Awards Committee, Physical Therapy Member, Institutional Review Board. Other committee / advisory board responsibilities: Leprino Foods, Nutrition Advisory Board 2015 Kraft Foods External Advisory Panel on Protein Nutrition 2013 Steering Committee. Protein Summit 2.0. Washington DC 2011 Sarcopenia Advisory Board. Takeda Global R&D 2011 Planning Committee, Institute of Medicine (IOM) Workshop on Nutrition and Healthy Aging in the Community NSBRI/NASA Space Human Factors & Habitability, Musculoskeletal Alterations Discipline Co-Lead Scientific Advisory Panel, American Egg Board Whey Protein Advisory Panel. National Dairy Council Mentor, Graduate Training Program in Space Life Sciences National Space Biomedical Research Institute and NASA Steering Committee. Protein Summit. Charleston, South Carolina Douglas Paddon-Jones 4

5 TEACHING EXPERIENCE: The University of Texas Medical Branch: Guest lecturer, PHYT 6342 Functional Training Techniques in Physical Therapy Course Coordinator: PHTY: Imaging of the Musculoskeletal and Neuromuscular Systems. Physical Therapy Lecturer. PMCH 6355: Tracer Methodology Lecturer. NASA BBSC 6102: Space physiology. Grad School of Biomedical Sciences Preventative Medicine and Community Health 2006 Facilitator. Cardiovascular and Pulmonary Physiology Course School of Medicine Course coordinator. Developing a Clinical Research Protocol 3 rd Year Surgery Rotation. School of Medicine Course coordinator. Metabolism Workshops. 3 rd Year Clinical Rotation. School of Medicine Facilitator. Essentials of Endocrinology and Reproduction. School of Medicine Student Supervisor. High School Summer Research Program National Space Biomedical Research Institute: NSBRI / NASA 2002 Student Supervisor. National Youth Leadership Forum on Medicine Graduate School of Biomedical Sciences The University of Queensland: Coordinator HM102 - Physical Fitness for Sport and Health 1998 Tutor HM331 Exercise Management Practicum 1997 Coordinator HM431 Major Practicum (Exercise Management) Tutor HM345 Sports Medicine Tutor HM274 Exercise Physiology Tutor HM373 Advanced Exercise Physiology Douglas Paddon-Jones 5

6 SUPERVISION AND MENTORING: 2016 Marlou Dirks External Ph.D Committee Member Maastricht University, The Netherlands 2016 Caoileann Murphy External Ph.D Committee Member McMaster University, Canada Elfego Galvan, Ph.D., RD. Supervisor, Postdoc Fellow Lauren O Conner Ph.D. Dissertation Committee Member Purdue University 2015 Jessica Spahn, MS, RCEP, CPT Supervisor, Research Coordinator Sneha Nagamma, M.D. Supervisor, Senior Laboratory Manager Emily Arentson-Lantz, Ph.D. Supervisor, Postdoc Fellow (Current: Research Scientist, UTMB) Paul Reidy Ph.D. Dissertation Committee Member (Current: Postdoc. University of Utah) - Kempner postdoctoral scholar Joni Mettler, Ph.D. Supervisor, Postdoc Fellow (Current: Assistant Professor, Texas State University) Madonna Mamerow, Ph.D. Supervisor, Postdoc Fellow David Gunderman Ph.D. Dissertation Committee Member (Current: Postdoc. University of Florida) Barbara Doucet, OTR, Ph.D. Mentor, RRCD Scholar, Division of Rehabilitation Sciences (Current: Assistant Professor, LSU) Douglas Paddon-Jones 6

7 Kirk English Ph.D. Mentor (Current: Senior Scientist, NASA-Johnson Space Center) - Charles F. Otis Endowed Award for Clinical Research Donald Micks Scholarship Recipient Emily Dupree Scholarship Recipient Texas Space Grant Consortium Fellow Shanon Casperson Ph.D. Co-Mentor and Dissertation Committee Member (Current: Postdoc Fellow USDA-ARS, North Dakota) - Peyton and Lydia Schapper Endowed Scholarship Energy and Macronutrient Metabolism Research Interest Section of the American Society for Nutrition Award Energy and Macronutrient Metabolism Research Interest Section of the American Society for Nutrition Award Isotec Student Sponsorship at Experimental Biology Peyton and Lydia Schapper Endowed Scholarship The American Physiological Assoc., Environmental & Exercise Physiology, Predoctoral Gatorade Award Isotec Student Sponsorship at Experimental Biology Christopher Fry Ph.D. Dissertation Committee Member (Current: Assistant Professor, UTMB) - Kempner postdoctoral scholar William Amonette Ph.D. Dissertation Committee Member (Current: Assistant Professor, University of Houston) Erin Glynn Ph.D. Dissertation Committee Member (Current: Senior Scientist, Beach Body LLC) T. Brock Symons, Ph.D. Supervisor, Postdoc Fellow (Current: Assistant Professor, University Louisville) Melanie Green-Cree, M.D., Ph.D. Ph.D. Preventative Medicine and Community Health (Current: Instructor, University of Colorado) Douglas Paddon-Jones 7

8 RESEARCH ACTIVITIES: Clinical Translational Research: My research program focuses on the regulation of muscle metabolism, mass and function in healthy and at-risk populations. Thematic areas include: i) the effects of physical inactivity (bed rest) on young, middle-aged and older adults ii) the effects of amino acid / protein consumption on acute markers of anabolism Recent highlights from our team include: demonstrating that physical inactivity greatly accelerates the loss of muscle mass and function in middle aged and older adults showing that nutritional (amino acid/leucine/whey) support may partially protect muscle health during periods of inactivity proposing the "Catabolic Crisis Model" of muscle/function loss as an opportunity to provide targeted prevention and treatment interventions conceiving and providing proof of concept for the "Even Protein Distribution" theory GRANT SUPPORT: Ongoing RO1 NR Paddon-Jones (PI) 10/11-10/17 NIH/NINR Preserving muscle mass and function in bedridden older adults The goal of this study is to reduce the negative consequences of physical inactivity and promote rehabilitation in aging muscle. (Total costs: $2.7M) Dairy Research Institute Paddon-Jones (PI) 09/12-12/16 National Dairy Council Whey protein, aging and physical inactivity The goal of this study is to determine if whey protein supplementation can preserve muscle mass and function during inactivity. (Total costs: $565K) Dairy Research Institute Paddon-Jones (PI) 06/13-07/16 Dairy Council of California Distributed protein intake, whey protein and aging. The goal is to optimize protein distribution and reduce muscle and function loss during bed rest. (Total costs: $178K) Douglas Paddon-Jones 8

9 Ongoing collaborative U01AR Rasmussen (PI) 12/16-12/21 NIH Molecular Transducers of Physical Activity in Humans, Adult Clinical Center. The goal is to assemble a comprehensive map of the molecular changes that occur in response to movement and relate these changes to the benefits of physical activity. Role: Clinical research core leader R56 AG Rasmussen (PI) 09/15-08/16 NIH/NIAMS Nutrient Sensing and Signaling in Aging Muscle The goal is to determine the role of muscle mtorc1 signaling in the etiology of anabolic resistance in older adults and whether physical activity interventions can be used as a treatment to reverse sarcopenia and improve the anabolic response to daily nutrition. Role: Co-Investigator P30 AG Volpi (PI) 06/10-04/20 NIH/NIA UTMB Claude Pepper Older Americans Independence Center The goals of this center grant is to support basic and clinical research on ways for elderly Americans to lead a more independent life for as long as possible. The center is focused on translating basic findings of muscle biology in aging to improve functional outcomes and recovery from illness in older adults. Role: Co-Investigator, Co-leader: Clinical Research Resource Core Industry Campbell (PI) 10/13-09/16 National Pork Board, American Egg Board-Egg Nutrition Center, Dairy Research Institute, and National Cattlemen's Beef Association Effects of dietary protein patterning on weight loss and resistance training-induced changes in body composition, skeletal muscle, and indices of metabolic syndrome. The goal is to evaluate the effects of patterning of dietary protein intake on energy-restriction induced changes. Site: Purdue University Role: Co-I Industry Campbell (PI) 05/ /2017 National Cattlemen s Beef Association and National Pork Board. Effects of incorporating red meat into a Mediterranean-style dietary pattern on cardiometabolic and emotional well-being. This research project will assess the impact of including greater amounts of red meat in a Mediterranean-style dietary pattern on changes in metabolic and emotional well-being. Site: Purdue University Role: Co-I Douglas Paddon-Jones 9

10 Completed R21 AR Lang (PI) 07/12-08/14 NIH/NINR PET/CT of Skeletal Muscle Amino Acid Kinetics Site: University of California San Francisco Role: Co-I NNJ08ZSA002N Paddon-Jones (PI) NSBRI 06/09-06/13 An integrated low-volume nutritional countermeasure to maintain muscle mass and function during space exploration. Abbott Education Paddon-Jones (PI) 09/12-10/13 Seminar Series in Rehabilitation and Nutrition. High Point Pharmaceuticals Paddon-Jones (PI) 09/12-06/13 A randomized, double-blind, placebo controlled, phase I study to evaluate the safety and tolerability of 28 day treatment with HPP593 capsules in healthy volunteers during and after limb immobilization. NCBA Paddon-Jones (PI) 06/09 07/11 National Cattlemen s Beef Association Protein Needs for Optimal Meal Response RO1 Sheffield-Moore (PI) 05/08-05/012 NIH/NIA Nutrition and anabolic interventions in cancer cachexia Role: Co-I UTMB Volpi (PI) 01/09-01/11 Institute Translational Science Multidisciplinary Translational Team Grant: Muscle Aging and Sarcopenia. Role: Co-I/Project coordinator RO1 AG Sheffield-Moore (PI) 09/03/05/09 NIH/NIA Muscle Perfusion and Protein Metabolism in Elderly and Young Role: Co-I UT TeleCampus Utsey (PI) 08/08-08/09 Pharmacology and Imaging: Online courses for DPT students and practicing physical therapist Role: Co-I/Course Instructor UTMB Paddon-Jones (PI) 04/07-04/08 Claude D. Pepper Older Americans Independence Center Restoration of Cell Signaling and Muscle Protein Synthesis in the Elderly Douglas Paddon-Jones 10

11 UTMB Paddon-Jones (PI) 12/07-08/08 Center for Rehabilitation Sciences Infrastructure grant to support submitted PO1 Translational Research in Muscle Metabolism Industry Paddon-Jones (PI) 06/05 09/07 National Cattlemen s Beef Association Effect of dose and composition of dietary beef on muscle protein anabolism in young and elderly NNJ04HD68G. Ferrando/ Paddon-Jones (PI) 08/04-05/07 NASA Artificial gravity as a multi-system countermeasure to bedrest deconditioning NPFR Paloski (PI) 07/05-06/08 NASA 90 Day Bedrest Campaign 3C. Role: Project lead, muscle team NCBA Paddon-Jones (PI) 03/05 09/05 National Cattlemen s Beef Association Beef ingestion and muscle protein metabolism GCRC Pilot Program Grant Paddon-Jones (PI) 06/02 06/03 Regulation of muscle protein synthesis in the young and elderly Role: PI AG Evans (PI) 07/05-06/06 NIH/NIA Program Project Bedrest and Aging: Amino Acid Supplementation and Muscle (UTMB/UAMS) Role: Co-I R01 AG Wolfe (PI) 09/03 5/08 NIH Muscle Protein Metabolism and Nutrition in the Elderly Role: Co-I NPFR00205 Wolfe (PI) 05/01-01/04 National Space Biological Research Institute Skeletal muscle response to bedrest and cortisol induced stress Role: Co-I MEMBERSHIP IN SCIENTIFIC SOCIETIES: Sports Medicine Australia American Physiological Society American College of Sports Medicine American Society for Nutrition Douglas Paddon-Jones 11

12 HONORS AND AWARDS: 2016 Sheridan Lorenz Distinguished Professor in Aging and Health The University of Texas Medical Branch 2015 Fellow. American College of Sports Medicine 2012 The Max K. Horwill Distinguished Nutrition Lectureship Saint Louis University 2012 Senior Fellow, Sealy Center on Aging The University of Texas Medical Branch 2009 SHP Award for Research Excellence The University of Texas Medical Branch 2006 Vernon Young International Award for Amino Acid Research American Society for Nutrition 2002 Fellow, Sealy Center on Aging The University of Texas Medical Branch 1999 Warren Walsh Memorial Award Outstanding Ph.D. Graduate. The University of Queensland 1998 Gatorade Sports Science Institute Student Research Award Doctoral Thesis. The University of Queensland Post-Graduate Research Scholarship The University of Queensland Post-Graduate Scholarship Ball State University, IN. USA NIH STUDY SECTION REVIEWS: 2015 National Center for Complementary & Integrative Health [NCCIH)] Study Section, November 4 National Institute of Diabetes and Digestive and Kidney Diseases [NIDDK] Special Emphasis Panel, July 9 Special Emphasis Panel. March NIH-Nursing and Related Clinical Sciences [NRCS] Study Section October NIH - Musculoskeletal Rehabilitation Sciences [MRS] Study Section June Douglas Paddon-Jones 12

13 A. ARTICLES IN PEER-REVIEWED JOURNALS: H-index : Arentson-Lantz EJ, Saeed IH, Frassetto LA, Masharani U, Harnish RJ, Seo Y, VanBrocklin HF, Hawkins RA, Mari-Aparici C, Pampaloni MH, Slater J, Paddon-Jones D, Lang TF. 11 C-Lmethyl methionine dynamic PET/CT of skeletal muscle: response to protein supplementation compared to L-[ring 13C6] phenylalanine infusion with serial muscle biopsy. Ann Nucl Med. Mar Ellison, J.B., Drummond, M. Dickinson, J.M., McGaugh, J.M., Paddon-Jones, D., Volpi, E. Short-Term Intensive Rehabilitation Induces Recovery of Physical Function After 7 Days of Bed Rest in Older Adults. J. of Acute Care Physical Ther. 7(4): Lamon, S. Zacharewicz, E. Arentson-Lantz, E., Della Gatta, P.A., Ghobrial, L., Gerlinger- Romero, F., Garnham, A., Paddon-Jones, D., Russell, A.P. Erythropoietin does not enhance skeletal muscle protein synthesis following exercise in young and older adults. Frontiers in Physiology. 8;7: English, K.L., Mettler, J.A., Ellison JB., Mamerow, M.M., Arentson-Lantz, E., Pattarini JM., Ploutz-Snyder R., Sheffield-Moore, M., Paddon-Jones, D. Leucine partially protects muscle mass and function during bed rest in middle-aged adults. Am. J. Clin. Nutr. 103(2): Arentson-Lantz E., English KL, Paddon-Jones D., Fry CS. Atrophy of skeletal muscle fibers and decline in satellite cell content in middle-aged adults during bed rest. J Appl. Physiol. 120(8): Markofski MM, Dickinson JM, Drummond MJ, Fry CS, Fujita S, Gundermann DM, Glynn EL, Jennings K, Paddon-Jones D, Reidy PT, Sheffield-Moore M, Timmerman KL, Rasmussen BB, Volpi E. Effect of age on basal muscle protein synthesis and mtorc1 signaling in a large cohort of young and older men and women. Exp Gerontol. 65: Mamerow, M.M., Mettler, J.A., English, K.L., Casperson, S.L., Arentson-Lantz, E., Sheffield- Moore, M., Layman, D.K., Paddon-Jones, D. Dietary Protein Distribution Positively Influences 24-h Muscle Protein Synthesis in Healthy Adults. J. Nutr /jn Casperson SL, Sheffield-Moore M, Hewlings SJ, Paddon-Jones D. Leucine supplementation chronically improves muscle protein synthesis in older adults consuming the RDA for protein. Clin. Nutr. 31(4): Drummond MJ, Dickinson JM, Fry CS, Walker DK, Gundermann DM, Reidy PT, Timmerman KL, Markofski MM, Paddon-Jones D, Rasmussen BB, Volpi E. Bed rest impairs skeletal muscle amino acid transporter expression, mtorc1 signaling, and protein synthesis in response to essential amino acids in older adults. Am J Physiol Endocrinol Metab.15; 302(9):E Douglas Paddon-Jones 13

14 10. Sheffield-Moore, M., Dillon, E.L., Casperson, S.L., Gilkison, C.R., Paddon-Jones, D., Durham, W.J., Grady, J.J., Urban, R.J. A Randomized Pilot Study of Monthly Cycled Testosterone Replacement or Continuous Testosterone Replacement Versus Placebo in Older Men. J Clin Endocrinol Metab. 96(11):E Symons T.B., Sheffield-Moore, M., Mamerow, M., Wolfe,R.R. and Paddon-Jones, D. The Anabolic Response to Resistance Exercise and a Protein-Rich Meal is not Diminished by Age. J. Nutr. Health and Aging. 15(5): Durham WJ, Casperson SL, Dillon EL, Keske MA, Paddon-Jones D, Sanford AP, Hickner RC, Grady JJ, Sheffield-Moore M. Age-related anabolic resistance after endurance-type exercise in healthy humans. FASEB J. 24(10): Cree, M.G., Paddon-Jones, D., Newcomer, B.R., Ronsen, O, Aarsland, A., Wolfe, R.R., Ferrando A. Twenty-eight-day bed rest with hypercortisolemia induces peripheral insulin resistance and increases intramuscular triglycerides. Metabolism. 59 (5): Ferrando*, A.A., Paddon-Jones*, D. Hays, N.P., Kortebien, P., Ronsen, O., Williams, R.H., McComb, A., Symons, T.B., Wolfe, R.R., Evans, W. EAA supplementation to increase nitrogen intake improves muscle function during bed rest in the elderly. (*contributed equally)clin. Nutr. 29(1): Symons T.B., Sheffield-Moore M., Chinkes D.L, Ferrando A.A., and Paddon-Jones D. NASA Artificial gravity maintains skeletal muscle protein synthesis during 21 days simulated microgravity. J.Appl. Physiol. 107(1): Symons T.B., Sheffield-Moore, M., Wolfe,R.R. and Paddon-Jones, D. A moderate serving of high-quality protein maximally stimulates skeletal muscle protein synthesis in young and elderly. J. Am. Dietetic Assoc. 109(9): Dillon E.L., Sheffield-Moore, M., Paddon-Jones, D., Gilkison, C., Sanford, A.P., Casperson, S.L., Jiang, J., Chinkes, D.L. and Urban, R.J. Amino acid supplementation increases lean body mass, basal muscle protein synthesis and IGF-I expression in older women. J. Clin. Endocrinol. Metab., 94(5): Kortebein P., Symons, T.B., Ferrando, A.A., Paddon-Jones, D., Ronsen, O., Protas, E., Conger, S., Lombeida, J., Wolfe, R.R., Evans, W.J. Functional impact of ten days bed rest in healthy older adults. J. Geron. 63(10): Katsanos CS, Chinkes DL, Paddon-Jones D, Zhang XJ, Aarsland A, Wolfe RR. Whey protein ingestion in elderly persons results in greater muscle protein accrual than ingestion of its constituent essential amino acid content. Nutr Res. 28(10): Cree M.G., Newcomer B.R., Read, L.K., Sheffield-Moore M., Paddon-Jones D., Chinkes, D., Aarsland, A., Wolfe, R.R. Plasma triglycerides are not related to tissue lipids and insulin sensitivity in elderly following PPAR-alpha agonist treatment. Mech Ageing Dev. 128(10): Douglas Paddon-Jones 14

15 21. Dillon E.L., Volpi E., Wolfe R.R., Sinha S., Sanford A.P., Concepcion A.D., Urban R.J., Casperson S.L., Paddon-Jones D., Sheffield-Moore M. Amino acid metabolism and inflammatory burden in ovarian cancer patients undergoing intense oncological therapy. Clin. Nutr. 26(6): Symons, T.B., Cocke, T.L., Schutzler, S.E., Wolfe, R.R. and Paddon-Jones, D. Aging does not impair the anabolic response to a protein-rich meal. Am. J. Clin. Nutr. 86; Fitts, R.H., Romatowski, J., Peters, J., Lim,W., Ferrando, A.A., Paddon-Jones, D., Wolfe, R.R. Effect of essential amino acid supplements on the functional capacity of fast- and slow-twitch muscle fibers in response to bed rest. Am. J. Physiol. Cell. 293(1):C Uchakin, P.N., Stowe, R.P., Paddon-Jones, D., Ferrando, A.A., Tobin, B.W., Wolfe, R.R. Effects of bed-rest on type 1 vs. type 2 cytokine secretion and latent herpes virus reactivation. Aviat Space Environ Med. 78(6): Paddon-Jones, D., Sheffield-Moore, M., Cree,M.G., Hewlings, S.J., Aarsland, A.A., Wolfe, R.R., Ferrando, A.A. Increased muscle protein catabolism during inactivity and stress. J. Clin. Endocrinol Metab. 91(12): Sheffield-Moore, M., Paddon-Jones, D., Casperson,, S.L., Gilkison, C., Volpi, E., Wolf, S.E., Jiang, J., Rosenblatt, J., Urban, R.J. Androgen Therapy Induces Muscle Protein Anabolism in Older Women. J. Clin. Endocrinol Metab. Oct;91(10): Zwart, S.R, Davis-Street, J.E., Paddon-Jones, D., Ferrando, A.A., Wolfe, R.R., Smith, S.M. Amino acid supplementation increases bone resorption during simulated weightlessness. J. Appl. Physiol. 99: , Paddon-Jones, D., Sheffield-Moore, M., Zhang X.J, Katsanos, C.S., and Wolfe, R.R. Differential stimulation of muscle protein synthesis in elderly humans following isocaloric ingestion of amino acids or whey protein. Experimental Gerontology. Nov. 22., Paddon-Jones, D., Keech, A., Lonergan, A., Abernethy, P. Differential expression of muscle damage in humans following acute fast and slow velocity eccentric exercise. J Sci. and Med. in Sports. Sep;8(3): Paddon-Jones, D., Sheffield-Moore, M., Urban, R.J., Aarsland, A., Wolfe, R.R. Ferrando, A.A. The catabolic effects of prolonged inactivity and acute hypercortisolemia are offset by dietary supplementation. J. Clin. Endocrinol Metab. 90(3): Paddon-Jones, D., Sheffield-Moore, M., Aarsland, A., Wolfe, R.R., Ferrando, A.A. Exogenous amino acids stimulate human muscle anabolism without interfering with the response to mixed meal ingestion. Am. J. Physiol. Endocrinol. Metab., 288(4):E Sheffield-Moore, M., Paddon-Jones, D., Sanford, A. P., Rosenblatt, J. I., Matlock, A. G., Cree, M. G. and Wolfe, R.R. Mixed muscle and hepatic-derived plasma protein metabolism is Douglas Paddon-Jones 15

16 differentially regulated in older and younger men following resistance exercise. Am. J. Physiol. Endocrinol. Metab.,288(5):E Paddon-Jones, D., Sheffield-Moore, M., Urban, R.J., Sanford, A.P., Aarsland, A., Wolfe, R.R. Ferrando, A.A. Essential amino acid and carbohydrate supplementation ameliorates muscle protein loss during 28 days bedrest. J. Clin. Endocrinol Metab. Sept Sheffield-Moore, M., Yeckel, C. W., Volpi, E., Wolf, S. E., Morio, B., Chinkes, D. L., Paddon- Jones, D. and Wolfe R. R. Post-exercise protein metabolism in older and younger men following moderate intensity aerobic exercise. Am. J. Physiol. Endocrinol. Metab., 287(3), E , Paddon-Jones, D., Sheffield-Moore, M., Zhang X-J, Volpi, E., Wolf, S.E., Aarsland, A., Ferrando, A.A. and Wolfe, R.R. Amino acid ingestion improves muscle protein synthesis in the young and elderly. Am. J. Physiol. Endocrinol. Metab. Oct Paddon-Jones, D., Sheffield-Moore, M., Creson, D.L., Wolf, S.E., Sanford, A.P., Wolfe, R.R., and Ferrando, A.A. Hypercortisolemia alters muscle protein anabolism following ingestion of essential amino acids. Am. J. Physiol. Endocrinol. Metab. Feb Ferrando, A.A., Sheffield-Moore, M., Paddon-Jones, D., Wolfe, R.R., and Urban, R.J. Differential anabolic effects of testosterone and amino acid feeding in older men. J. Clin. Endocrinol Metab. 88: Ferrando, A.A., Paddon-Jones, D., and Wolfe, R.R. Alterations in protein metabolism during space flight and inactivity. Nutr. 18: Rasmussen, B. Holmbäck, U., Volpi, E. Morio-Liondore, B. Paddon-Jones, D. and Wolfe. R. Malonyl-CoA regulates functional carnitine palmitoyl-transferase I activity and fat oxidation in human skeletal muscle. J. Clin. Invest. 110: Paddon-Jones, D., Keech, A. and Jenkins, D. Short term ß-hydroxy-ß-methylbutyrate supplementation does not reduce symptoms of eccentric muscle damage. Int. J. Sports Nutr. 11 (4): Paddon-Jones, D., Leveritt, M., Lonergan, A. and Abernethy, P. Adaptation to chronic eccentric exercise in humans: the influence of contraction velocity. Eur. J. Appl. Physiol. 85: Paddon-Jones, D. and Abernethy, P. Acute adaptation to low volume eccentric exercise. Med. Sci. Sports Exerc. Jul; 33 (7): Paddon-Jones, D., Muthalib, M. and Jenkins, D. The effects of a repeated bout of eccentric exercise on indices of muscle damage and delayed onset muscle soreness. J. Sci. Med. Sport. 3(1): Paddon-Jones, D. and Pearson, D.R. The cost-effectiveness of pre-exercise carbohydrate meals and their impact on endurance performance. J. Strength and Cond. Res. 12(2) Douglas Paddon-Jones 16

17 45. Paddon-Jones, D. and Quigley, B.M. The effect of cryotherapy on muscle soreness and strength following eccentric exercise. Int. J. Sports Med. 18(8) Douglas Paddon-Jones 17

18 INVITED REVIEWS 1. Paddon-Jones, D., Cross-Bu, J.A., Phillips, S.M, Morris, C.R., Wernerman, J. Variation in protein origin and utilization: clinical application. Nutr. Clin. Practice. 32(1_suppl):48S-57S Phillips, S.M, Dickerson, R.N., Moore, F.A., Paddon-Jones, D., Weijs, P.J. Protein turnover and metabolism in the elderly ICU patient. Nutr. Clin. Practice. 32(1_suppl):112S-120S. 3. Rugeles SJ, Ochoa Gautier JB, Dickerson RN, Coss-Bu JA, Wernerman J, Paddon-Jones D. How Many Nonprotein Calories Does a Critically Ill Patient Require? A Case for Hypocaloric Nutrition in the Critically Ill Patient. Nutr Clin Pract Apr;32(1_suppl):72S-76S. 4. Wernerman J, Morris CR, Paddon-Jones D, Sarav M. Assessment of Protein Turnover in Health and Disease. Nutr Clin Pract Apr;32(1_suppl):15S-20S. 5. Hurt RT, McClave SA, Martindale RG, Ochoa Gautier JB, Coss-Bu JA, Dickerson RN, Heyland DK, Hoffer LJ, Moore FA, Morris CR, Paddon-Jones D, Patel JJ, Phillips SM, Rugeles SJ, Sarav Md M, Weijs PJ, Wernerman J, Hamilton-Reeves J, McClain CJ, Taylor B. Summary Points and Consensus Recommendations From the International Protein Summit. Nutr Clin Pract Apr;32(1_suppl):142S-151S. 6. Galvan, E., Arentson-Lantz, E.J., Lamon, S., Paddon-Jones, D. Protecting Skeletal Muscle with Protein and Amino Acid during Periods of Disuse. Nutrients. 8(7), Paddon-Jones, D., Campbell, W.W., Jacques, P., Kritchevsky, S.B., Moore, L., Rodriguez, N., van Loon, L.C.J. Protein and Healthy Aging. Am. J. Clin. Nutr. 101 (6S), Arentson-Lantz, E., Clairmont, S, Paddon-Jones, D., Tremblay, A., Elango, R. Protein: A nutrient in focus. Appl Physiol Nutr Metab. Aug;40(8): Paddon-Jones, D. and Leidy, H. Protein and muscle in older persons. Curr. Opin. Clin. Nutr. Metab. Care. 17(1): English, K. and Paddon-Jones, D. Protecting muscle mass and function in older adults during bed rest. Curr. Opin. Clin. Nutr. Metab. Care. 13(1): Paddon-Jones, D. and Rasmussen,B.B. The Role of Protein Intake on the Preservation of Muscle Mass in Aging. Curr. Opin. Clin. Nutr. Metab. Care. Jan;12(1): Paddon-Jones, D., Short, K.R., Campbell, W.W., Garlick, P.J., Volpi, E., Wolfe, R.R. The role of dietary protein in the sarcopenia of aging. Am. J. Clin. Nutr. 87(5):1562S-1566S Paddon-Jones, D., Westman, E., Mattes, R.D., Wolfe, R.R., Astrup, A.A., Westerterp- Plantenga, M.. Protein, weight management and satiety. Am. J. Clin. Nutr. 87(5):1558S-1561S Douglas Paddon-Jones 18

19 14. Paddon-Jones, D. Interplay of stress and physical inactivity on muscle loss: nutritional countermeasures. Recent Advances in Nutritional Sciences. J. Nutr. Aug;136(8): Sheffield-Moore M., Paddon-Jones, D. and Urban, R.J. Amino Acid Supplementation and Skeletal Muscle Metabolism in Adults. Hormone Research. 66 Suppl 1: Ferrando, A.A., Paddon-Jones, D. and Wolfe, R.R. Bedrest and myopathies. Current Opin. Clin Nutr & Critical Care. Jul;9(4): Paddon-Jones, D., Wolfe, R.R and Ferrando, A.A. Amino acid supplementation for reversing bedrest and steroid myopathies. J. Nutr. 135(7): , Paddon-Jones, D., Børsheim, E., Wolfe, R.R. Potential ergogenic effects of arginine and creatine supplementation. J. Nutr. 134:2888S-2894S, Casiano, E., Paddon-Jones, D., Ostir, G., and Sheffield-Moore, M. Essential Components of Functional Status Tests: A Guide for Healthcare Professionals. Phys. Ther. Reviews. 7: 2002 B. BOOK CHAPTERS / LETTERS 1. [editorial] Paddon-Jones, D. Protein Recommendations for Bodybuilders: In This Case, More May Indeed Be Better. J. Nutr Mar [letter] Arentson-Lantz E., English KL, Paddon-Jones D., Fry CS. The intersection of disuse-induced muscle atrophy and satellite cell content: reply to Snijders, Nederveen, and Parise. J.Appl.Physiol , [letter] Phillips, S.M., Tipton, K.D., van Loon, L.J.C., Verdijk, L.B., Paddon-Jones, D., Close, G.L. Exceptional body composition changes attributed to collagen peptide supplementation and resistance training in older sarcopenic men. Letter to the Editor. British J. Nutr. 116(3): Paddon-Jones, D., and Russell, A. Functional Status and Physical Activity in Older Adults Handbook of Clinical Nutrition and Aging, 3E, (Bales, Locher, and Saltzman eds) Paddon-Jones, D., and Van Loon, L. Nutritional Approaches to Prevent Sarcopenia. Sarcopenia. Wiley Publishers. (Cruz-Jentoft and Morley eds) Sheffield-Moore, M., Paddon-Jones, D. and Urban, R.J. Amino acid supplementation and skeletal muscle metabolism in adults. Hormone Research. 66 (Suppl. 1): Sheffield-Moore M., Paddon-Jones D., Cree M. G., Lackan, D. W. and Urban, R. J. Effect of Androgens on Muscle, Bone, and Hair in Men. In: Tan RS (ed.). Aging Men's Health. New York: Thieme Medical Publishers; 83-93: 2005 Douglas Paddon-Jones 19

20 C. SELECTED INVITED PRESENTATIONS / KEY NOTE ADDRESSES 1. South East Asia Dairy Conference. Singapore, December Protein Think Tank. Chicago. October, American Dairy Association/ Wegmans Protein Symposium. NY. October, St. Luke s Hospital Grand Rounds, Boise Idaho. October Idaho Pressure Ulcer Prevention Coalition. Boise Idaho. October Alpha Protein Summit, Singapore, October International Egg Nutrition, Functional Food and Human Health Symposium, Banff, Oct International Protein Summit, Protein in the ICU. Nestle. Charleston SC. September, Sports nutrition symposium. Boise, Idaho. August, US Dairy Export Council Key Note Seminar. Denpasar, Bali. August ACSM. Dietary Protein in Support of Exercise Adaptations and Health. Boston. June Live Well Conference. Austin Tx. April, Research Symposium Keynote Address. Louisiana State University HSC. March, NEP Seminar Series, University of Missouri. February AND-FNCE Annual Meeting. Nashville. October, Gerontological Advanced Practice Nurses Association. San Antonio, September, Institute of Food Technologists Annual Meeting & Food Expo. Chicago, July, Asian Congress of Nutrition, Yokohama, Japan. May, International Conference on Frailty & Sarcopenia Research. Boston. April, Idaho Academy of Nutrition and Dietetics Annual Meeting. Boise. April, Oklahoma State University, Health and Wellness Symposium. April, Gerontological Society of America Annual Meeting. Washington DC. November, Enhanced Recovery after Surgery (ERAS) symposium. Edmonton CA. October, Nestlé Nutrition Institute, Commonwealth Scientific and Industrial Research Organization (CSIRO) and Australasian Society for Parenteral and Enteral Nutrition (AUSPEN) symposium. Melbourne, Australia. October, th International Whey Conference. Rotterdam. September, Chinese Nutrition Society Annual Meeting. Shanghai. June, American College of Sports Medicine. Florida. May, th Nutrition and Health: State of the Science. University of Arizona. April, Texas Academy of Nutrition and Dietetics Annual Meeting. Corpus Christi. April, Colorado Academy of Nutrition and Dietetics Annual Meeting. Denver. April, Dairy Farmers of Canada Symposium on Nutrition and Health. Edmonton, Toronto, Moncton, Montreal. December, Culinary Institute of America. New York. October, Protein Summit 2.0. Washington DC. October, American Assn. of Nurse Practitioners. National Conference. Las Vegas. June, Steve Nissan Honorary Seminar, Iowa State University, May, Canadian Nutrition Society Annual Meeting, Montreal. May, First Caribbean Nutrition Summit, Dominican Republic. May 2013 Douglas Paddon-Jones 20

21 38. 4th World Congress on Exercise is Medicine. Indianapolis. April, Nebraska Dietetic Association Annual Meeting. Overland Park, April, West Virginia Dietetic Association Annual Meeting. Marshall University, March, Nutrition Obesity Research Center (NORC), University of Alabama, Feb, US Dairy Export Council Key Note Seminar, Japan and Korea, November, ADA-FNCE Annual Meeting. Philadelphia, PA, October, SANCYD Congress. Seville, Spain. March, Sports, Cardiovascular Wellness and Nutrition Annual Conf., Baltimore, April British Association for Parenteral and Enteral Nutrition, Annual Conference. Nov Dietetic Forum. Culinary Institute of America, Hyde Park, NY. October, Spanish Society of Enteral and Parental Nutr. Annual Meeting, Girona, Spain. May Californian Society of Enteral and Parental Nutr. Los Angeles, May Rhode Island Dietetic Association, April EUGMS Dublin, Ireland, September US Dairy Export Council Key Note Seminar, Shanghai, China, September European Society of Enteral and Parenteral Nutrition (ESPEN), Nice, France. Aug Southern California Society of Enteral and Parental Nutrition, July, Institute of Food Technologists Annual Meeting & Food Expo. Chicago, July Utah Dietetic Association Annual Meeting, Ogden, UT. April Kentucky Dietetic Association Annual Meeting, Bowling Green, KY. April Iowa Dietetic Association Annual Meeting, Altoona, IA. November Abbott Nutrition Research Conference, Columbus OH, June USDA Seminar Program. Baltimore, MD. May Nebraska Dietetic Association Annual Meeting. Lincoln NB. April Missouri Dietetic Association Annual Meeting. Branson MZ. April American Society of Bariatric Physicians, Annual Meeting. Charleston, SC. April Texas Academy of Cardiovascular Pulmonary Rehab. Annual Meeting. March American Dietetic Assoc., Food & Nutrition Conference. Chicago, IL. October Protein Metabolism and Nutrition, Florida Dietetic Association, September Protein Think Tank and Summit, Seattle, WA September A Nutrition Adventure: Explore the Power of Protein, Kansas City, MO. May New Jersey Dietetic Association Annual Meeting, New Brunswick, NJ. May Nutrition & Aging XXII: Frailty in Older Adults. Little Rock, AR September US Dairy Export Council Seminar Series. Singapore, Jakarta, Surabaya. September Florida Dietetic Association Annual Meeting. San Marco Island. Fl. July Idaho Academy of Family Physicians, Annual Meeting. Boise, ID, May Texas Academy of Family Physicians, Scientific Assembly. Corpus Christi, July Weight Management Dietetic Practice Group, Annual Meeting. Scottsdale, May Sports, Cardiovascular and Wellness Nutrition Dietetic Practice Group Awards Luncheon and Annual Symposium. Austin, TX, April Grand Rounds. St. Luke s Hospital, Boise, ID. April, Ground Rounds. Mercy Medical Center, Nampa, ID. April, 2007 Douglas Paddon-Jones 21

22 79. Ground Rounds. Boise VA Hospital, Boise ID. April, Annual Physician Assistant Meeting, Sun Valley, ID. April, Clinical Nutrition Management Dietetic Practice Group (ADA). Tampa FL. March Live Well 2006: A Toast to the Senses and Science. Napa Valley. June, American Dietetic Association Nutrition News Forecast. Vancouver, May, Idaho Dairy Council, Annual Dietetic Conference. Idaho Falls, April, Grand Rounds, Eastern Idaho Regional Medical Center. Idaho Falls, April, Nutrition Research Discovery Symposium. Denver, CO. April, 2006 Douglas Paddon-Jones 22