Date of Preparation: December 8, 2017 A. GENERAL INFORMATION. 1. Name: Eun Sook KO Citizenship: Republic of Korea

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1 Date of Preparation: December 8, 2017 A. GENERAL INFORMATION 1. Name: Eun Sook KO Citizenship: Republic of Korea B. EDUCATIONAL & TRAINING BACKGROUND Degree Institution name and location Dates attended Year Awarded M.D. Gyeongsang National University College of Medicine M.S. Gyeongsang National University Graduate School PhD. Kangwon National University Graduate School Internship Gyeongsang National University Hospital Radiology Residency Gyeongsang Natl Univ. Hospital Radiology Fellowship (Breast Section) Seoul Natl Univ. Hospital C. PROFESSIONAL POSITIONS AND EMPLOYMENT Dates Position Institution name and location Clinical Assistant Professor, Department of Radiology, Gyeongsang Natl Univ Hospital, Jinju Radiologist, Department of Radiology, Korea Cancer Center Hospital, Seoul Clinical Assistant Professor, Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul present Assistant Professor, Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul D. PROFESSIONAL MEMBERSHIPS KSR (Korean Society of Radiology) KSBI (Korean Society of Breast Imaging) Public relations secretary 2016-now Training secretary KSMRM (Korean Society of Magnetic Resonance in Medicine) Scientific secretary (breast)

2 E. HONORS AND AWARDS F. BIBLIOGRAPHY Peer-Reviewed articles: 1. MRI of the breast for the detection and assessment of the size of ductal carcinoma in situ. Kim do Y, Moon WK, Cho N, Ko ES, Yang SK, Park JS, Kim SM, Park IA, Cha JH, Lee EH. Korean J Radiol Jan-Feb;8(1): Sonographically-guided 14-gauge core needle biopsy for papillary lesions of the breast. Ko ES, Cho N, Cha JH, Park JS, Kim SM, Moon WK. Korean J Radiol May-Jun;8(3): (First author) 3. Correlation between high resolution dynamic MR features and prognostic factors in breast cancer. Lee SH, Cho N, Kim SJ, Cha JH, Cho KS, Ko ES, Moon WK. Korean J Radiol Jan-Feb;9(1): Noncalcified ductal carcinoma in situ: imaging and histologic findings in 36 tumors. Kim JH, Ko ES, Kim do Y, Han H, Sohn JH, Choe du H. J Ultrasound Med Jul;28(7): Sonographic changes after removing all benign breast masses with sonographically guided vacuum-assisted biopsy. Ko ES, Han H, Lee BH, Choe du H. Acta Radiol Nov;50(9): (Corresponding ahuthor) 6. Background enhancement in Breast MR: Correlation with breast density in mammography and background echotexture in ultrasound. Ko ES, Lee BH, Choi HY, Kim RB, Noh WC. Eur J Radiol Dec;80(3): Triple-negative breast cancer: correlation between imaging and pathological findings. Ko ES, Lee BH, Kim HA, Noh WC, Kim MS, Lee SA. Eur Radiol May;20(5): (Corresponding ahuthor) 8. Invasive ductal carcinoma in a mammary hamartoma: case report and review of literature. Choi N, Ko ES. Korean J Radiol Nov-Dec;11(6): Application of sonoelastography: comparison of performance between mass and non-mass lesion. Ko ES, Choi HY, Kim RB, Noh WC. Eur J Radiol Apr;81(4): (Corresonding author) 10.Central washout sign in computer-aided evaluation of breast MRI: preliminary results. Ko ES, Choi HY, Lee BH, Noh WC, Kim RB. Acta Radiol Apr 1; 52(3):

3 11. Thyroid lymphoma: correlation of radiologic and pathologic features. Nam M, Shin JH, Han BK, Ko EY, Ko ES, Hahn SY, Chung JH, Oh YL. J Ultrasound Med Apr;31(4): Analysis of factors that influence the accuracy of magnetic resonance imaging for predicting response after neoadjuvant chemotherapy in locally advanced breast cancer. Ko ES, Han BK, Kim RB, Ko EY, Shin JH, Hahn SY, Nam SJ, Lee JE, Lee SK, Im YH, Park YH. Ann Surg Oncol Aug;20(8): (First author) 13. Primary anaplastic lymphoma kinase-negative anaplastic large-cell lymphoma of the breast in a male patient. Ko ES, Seol H, Shin JH, Ko EY. Br J Radiol Apr;85(1012):e Preoperative ultrasonographic features of papillary thyroid carcinoma predict biological behavior. Nam SY, Shin JH, Han BK, Ko EY, Ko ES, Hahn SY, Chung JH. J Clin Endocrinol Metab Apr;98(4): Comparison of new and established full-field digital mammography systems in diagnostic performance. Ko ES, Han BK, Kim SM, Ko EY, Jang M, Lyou CY, Chang JM, Moon WK, Kim RB. Korean J Radiol Mar-Apr;14(2): (First author) 16. MRI-guided intervention for breast lesions using the freehand technique in a 3.0-T closed-bore MRI scanner: feasibility and initial results. Choi HY, Kim SM, Jang M, Yun BL, Kim SW, Kang E, Park SY, Moon WK, Ko ES. Korean J Radiol Mar-Apr;14(2): Analysis of the effect of breast magnetic resonance imaging on the outcome in women undergoing breast conservation surgery with radiation therapy. Ko ES, Han BK, Kim RB, Ko EY, Shin JH, Nam SY, Nam M, Nam SJ, Lee JE, Kil WH, Lee SK. J Surg Oncol Jun;107(8): (First author) 18. Background parenchymal enhancement on breast MRI: Influence of menstrual cycle and breast composition. Kang SS, Ko EY, Han BK, Shin JH, Hahn SY, Ko ES. J Magn Reson Imaging Mar;39(3): Ultrasonography-guided core needle biopsy for the thyroid nodule: does the procedure hold any benefit for the diagnosis when fine-needle aspiration cytology analysis shows inconclusive results? Hahn SY, Shin JH, Han BK, Ko EY, Ko ES. Br J Radiol May;86(1025): Detectability and clinicohistological characteristics of small ( 1cm) invasive breast cancer. Yoo EY, Shin JH, Ko EY, Han BK, Cho EY, Nam SJ, Hahn SY, Ko ES. Eur J Radiol Oct;82(10):e

4 21. Predictive factors of malignancy in patients with cytologically suspicious for Hurthle cell neoplasm of thyroid nodules. Lee KH, Shin JH, Ko ES, Hahn SY, Kim JS, Kim JH, Oh YL. Int J Surg. 2013;11(9): Automated volumetric breast density estimation: a comparison with visual assessment. Seo JM, Ko ES, Han BK, Ko EY, Shin JH, Hahn SY. Clin Radiol Jul;68(7): Sonographic findings of pure ductal carcinoma in situ. Lee MH, Ko EY, Han BK, Shin JH, Ko ES, Hahn SY. J Clin Ultrasound Oct;41(8): Ultrasonographic elastography of thyroid nodules: Is adding strain ratio to colour mapping better? Chong Y, Shin JH, Ko ES, Han BK. Clin Radiol Dec;68(12): Stromal fibrosis of the breast: outcome analysis. Shin S, Ko ES, Han BK, Ko EY. Acta Radiol May;55(4): Ultrasonographic hyperechoic lesions of the breast: are they always benign? Nam SY, Ko ES, Han BK, Shin S, Ko EY, Shin JH, Hahn SY. Acta Radiol Jan;56(1): Role of diffusion-weighted imaging as an adjunct to contrast-enhanced breast MRI in evaluating residual breast cancer following neoadjuvant chemotherapy. Hahn SY, Ko EY, Han BK, Shin JH, Ko ES. Eur J Radiol Feb;83(2): Follicular variant of papillary thyroid carcinoma: distinct biologic behavior based on ultrasonographic features. Rhee SJ, Hahn SY, Ko ES, Ryu JW, Ko EY, Shin JH. Thyroid Apr;24(4): Apparent diffusion coefficient in estrogen receptor-positive invasive ductal breast carcinoma: correlations with tumor-stroma ratio. Ko ES, Han BK, Kim RB, Cho EY, Ahn S, Nam SJ, Ko EY, Shin JH, Hahn SY. Radiology Apr;271(1):30-7. (First author) 30. Intralesional saline injection for effective ultrasound-guided aspiration of benign viscous cystic thyroid nodules. Ko ES, Sung JY, Shin JH. Ultrasonography Apr;33(2): (First author) 31. A new full-field digital mammography system with and without the use of an advanced postprocessing algorithm: comparison of image quality and diagnostic performance. Ahn HS, Kim SM, Jang M, Yun BL, Kim B, Ko ES, Han BK, Chang JM, Yi A, Cho N, Moon WK, Choi HY. Korean J Radiol May-Jun;15(3):

5 32. Ultrasound findings of papillary thyroid carcinoma originating in the isthmus: comparison with lobe-originating papillary thyroid carcinoma. Hahn SY, Han BK, Ko EY, Shin JH, Ko ES. AJR Am J Roentgenol Sep;203(3): Effect of menstrual cycle and menopausal status on apparent diffusion coefficient values and detectability of invasive ductal carcinoma on diffusion-weighted MRI. Shin S, Ko ES, Kim RB, Han BK, Nam SJ, Shin JH, Hahn SY. Breast Cancer Res Treat Feb;149(3): Reproducibility of automated volumetric breast density assessment in short-term digital mammography reimaging. Ko ES, Kim RB, Han BK. Clin Imaging Jul-Aug;39(4): Shear-wave elastography in invasive ductal carcinoma: correlation between quantitative maximum elasticity value and detailed pathological findings. Cho EY, Ko ES, Han BK, Kim RB, Cho S, Choi JS, Hahn SY. Acta Radiol May;57(5): (Corresponding author) 36. Comparison of full-field digital mammography and digital breast tomosynthesis in ultrasonography-detected breast cancers. Nam KJ, Han BK, Ko ES, Choi JS, Ko EY, Jeong DW, Choo KS. Breast Oct;24(5): Prognostic Significance of a Complete Response on Breast MRI in Patients Who Received Neoadjuvant Chemotherapy According to the Molecular Subtype. Ko ES, Han H, Han BK, Kim SM, Kim RB, Lee GW, Park YH, Nam SJ. Korean J Radiol Sep-Oct;16(5): (First author) 38. Comparison between two-dimensional synthetic mammography reconstructed from digital breast tomosynthesis and full-field digital mammography for the detection of T1 breast cancer. Choi JS, Han BK, Ko EY, Ko ES, Hahn SY, Shin JH, Kim MJ. Eur Radiol Aug;26(8): Initial Experience with a Wireless Ultrasound-Guided Vacuum-Assisted Breast Biopsy Device. Choi ER, Han BK, Ko ES, Ko EY, Choi JS, Cho EY, Nam SJ. PLoS One Dec 2;10(12):e Direct binding of Copine3 with Jab1 activates downstream ErbB2 signaling and motility in SKBr3 breast cancer cells. Choi HY, Park N, Na JB, Ko ES, Park JY, Yoo JC. Oncol Rep Feb;35(2): Additional diagnostic value of shear-wave elastography and color Doppler US for evaluation of breast non-mass lesions detected at B-mode US. Choi JS, Han BK, Ko EY, Ko ES, Shin JH, Kim GR. Eur Radiol Oct;26(10):

6 42. Assessment of Invasive Breast Cancer Heterogeneity Using Whole-Tumor Magnetic Resonance Imaging Texture Analysis: Correlations With Detailed Pathological Findings. Ko ES, Kim JH, Lim Y, Han BK, Cho EY, Nam SJ. Medicine (Baltimore) Jan;95(3):e Background Parenchymal Enhancement on Preoperative Magnetic Resonance Imaging: Association With Recurrence-Free Survival in Breast Cancer Patients Treated With Neoadjuvant Chemotherapy. Choi JS, Ko ES, Ko EY, Han BK, Nam SJ. Medicine (Baltimore) Mar;95(9):e Prognostic Significance of Transverse Relaxation Rate (R2*) in Blood Oxygenation Level- Dependent Magnetic Resonance Imaging in Patients with Invasive Breast Cancer. Choi HY, Ko ES, Han BK, Kim EJ, Kim SM, Lim Y, Kim RB. PLoS One Jul 6;11(7):e Analysis of factors influencing the degree of detectability on diffusion-weighted MRI and diffusion background signals in patients with invasive breast cancer. Hahn SY, Ko ES, Han BK, Lim Y, Gu S, Ko EY. Medicine (Baltimore) Jul;95(27):e Breast Cancer Heterogeneity: MR Imaging Texture Analysis and Survival Outcomes. Kim JH, Ko ES, Lim Y, Lee KS, Han BK, Ko EY, Hahn SY, Nam SJ. Radiology Mar;282(3): Breast Imaging Reporting and Data System Category 3 Lesions Detected on Whole-Breast Screening Ultrasound. Nam SY, Ko EY, Han BK, Shin JH, Ko ES, Hahn SY. J Breast Cancer Sep;19(3): Shear wave elastography in the diagnosis of breast non-mass lesions: factors associated with false negative and false positive results. Park SY, Choi JS, Han BK, Ko EY, Ko ES. Eur Radiol Feb 6. doi: /s [Epub ahead of print]. 49. An audit of the results of ultrasound-guided core needle biopsy of mammography versus ultrasound screen-detected breast lesions. Rhee SJ, Han BK, Ko ES, Choi JS, Ko EY. J Breast Cancer Sep;19(3): Background parenchymal enhancement on breast MRI: association with recurrence-free survival in patients with newly diagnosed invasive breast cancer. Lim Y, Ko ES, Han BK, Ko EY, Choi JS, Lee JE, Lee SK. Breast Cancer Res Treat Jun;163(3): Metastatic internal mammary lymph nodes or mimickers on parasternal ultrasonography: focusing on their distribution and depth. Jeong CJ, Bae JM, Park SY, Han BK, Ko ES, Ko EY. Acta Radiol Jan 1: doi: / [Epub ahead of print]

7 52. Combination of shear-wave elastography and color Doppler: Feasible method to avoid unnecessary breast excision of fibroepithelial lesions diagnosed by core needle biopsy. Kim GR, Choi JS, Han BK, Ko EY, Ko ES, Hahn SY. PLoS One May 4;12(5):e Breast Cancer Screening With Mammography Plus Ultrasonography or Magnetic Resonance Imaging in Women 50 Years or Younger at Diagnosis and Treated With Breast Conservation Therapy. Cho N, Han W, Han BK, et al. JAMA Oncol Nov 1;3(11): Preoperative Axillary US in Early-Stage Breast Cancer: Potential to Prevent Unnecessary Axillary Lymph Node Dissection. Kim GR1, Choi JS1, Han BK1, Lee JE1, Nam SJ1, Ko EY1, Ko ES1, Lee SK1. Radiology Jul;288(1): Preoperative dynamic breast magnetic resonance imaging kinetic features using computeraided diagnosis: Association with survival outcome and tumor aggressiveness in patients with invasive breast cancer. Nam SY1, Ko ES2, Lim Y3, Han BK2, Ko EY2, Choi JS2, Lee JE4. PLoS One Apr 12;13(4):e Radiomics Signature on Magnetic Resonance Imaging: Association with Disease-Free Survival in Patients with Invasive Breast Cancer. Park H#1,2, Lim Y#3, Ko ES4, Cho HH5, Lee JE6, Han BK7, Ko EY7, Choi JS7, Park KW7 Clin Cancer Res Oct 1;24(19): Comparison of synthetic and digital mammography with digital breast tomosynthesis or alone for the detection and classification of microcalcifications. Choi JS1, Han BK2, Ko EY1, Kim GR3, Ko ES1, Park KW1 Eur Radiol Jun 21. doi: /s x. [Epub ahead of print] 58. Additional lesions seen in magnetic resonance imaging of breast cancer patients: the role of second-look ultrasound and imaging-guided interventions. Park SY1, Han BK1, Ko ES1, Ko EY1, Cho EY2 Ultrasonography Jun 23. doi: /usg [Epub ahead of print]

8 Books, book chapters and reviews: 1. Clinical Magnetic Resonance Imaging, Ilchokak, The breast, Biomedbook, 2017 Oral Presentation: 1. Papillary lesions of the breast: Comparison of US-guided 14-Gauge Automated Gun and 11- Gauge Directional Vacuum-assisted Biopsy Methods. KCR An analysis of False Negative US-guided Core Needle Biopsies of the Breast. KCR Periodic US findings after Removal of all US evidence during biopsy by US-guided Vacuum- Assisted Device. KCR An analysis of False Negative US-guided Core Needle Biopsies of the Breast. RSNA Periodic US findings after Removal of all US evidence during biopsy by US-guided Vacuum- Assisted Device. RSNA Triple-Negative Breast Cancer: Correlation between Imaging and Pathological Findings. KCR US elastography of thyroid nodule: Is adding strain ratio to color mapping better? RSNA Preoperative MRI of the Breast Cancer in Breast-conserving Surgery: Benefit or Not? RSNA Hyperechoic Lesions of the Breast on Sonography: Are They Always Benign? RSNA 10. Analysis of Factors Influencing Accuracy of MRI for Predicting Response After Neoadjuvant Chemotherapy in Locally Advanced Breast Cancer RSNA 11. Apparent diffusion coefficient in estrogen receptor-positive invasive ductal breast carcinoma: Correlations with the tumor-stroma ratio. RSNA Effect of menstrual cycle and menopausal status on ADC values and detectability of invasive ductal carcinoma on diffusion-weighted MR images. RSNA Background Parenchymal Enhancement on Preoperative Magnetic Resonance Imaging: Association with Recurrence-Free Survival in Breast Cancer Patients Treated with Neoadjuvant Chemotherapy. RSNA Analysis of Factors Influencing the Detectability on Diffusion-Weighted MRI and Diffusion Background Signals in Invasive Breast Cancer Patients. RSNA 2015.

9 15. Prognostic Significance of Transverse Relaxation Rate (R2*) in Blood Oxygenation Level- Dependent Magnetic Resonance Imaging in Patients with Invasive Breast Cancer. SBI Breast Cancer Heterogeneity Assessed by Texture Analysis in Magnetic Resonance Imaging: Its Relationship with Survival Outcomes. RSNA Radiomics Nomogram: Prediction of Recurrence-Free Survival in Patients with Invasive Breast Cancer. RSNA Preoperative Breast MR Imaging Kinetic Features Using Computer-Aided Diagnosis: Association with Survival Outcome in Invasive Breast Cancer Patients. RSNA Radiomics Signature on 3T DCE-MRI for Estrogen Receptor-Positive Invasive Breast Cancers: Preliminary Results in Predicting Oncotype DX Test Recurrence Score. RSNA 2017