CURRICULUM VITAE. Education 1994 M.D.: Seoul National University College of Medicine (Summa cum laude)

Transcription

1 CURRICULUM VITAE Name : Wonshik Han, M.D., Ph.D. Title: Associate Professor, Department of Surgery and Cancer Research Institute, Seoul National University College of Medicine Chief of the Breast Care Center, Seoul National University Hospital 28 Yongon-dong, Chongno-gu Seoul , South Korea Tel: , Fax: , hanw@snu.ac.kr Education 1994 M.D.: Seoul National University College of Medicine (Summa cum laude) 2003 M.S.: Seoul National University College of Medicine 2005 Ph.D.: Seoul National University College of Medicine Training Internship and General Surgery Residency, Seoul National University Hospital Army Surgeon (Captain), Republic of Korea Army Fellow in Breast Surgery, Seoul National University Hospital 2010 International Breast Surgery Fellowship according to EUSOMA guideline: Marien Hospital Dusseldorf under supervision of Prof. Werner Audretsch

2 Faculty appointment Clinical Assistant Professor, Department of Surgery, Seoul National University Hospital Mar Assistant Professor, Department of Surgery Seoul National University College of Medicine Apr Associate Professor, Department of Surgery Seoul National University College of Medicine Oct Joint Appointment of Faculty Members Seoul National University Cancer Research Institute Professional Societies 1. Member of Board of Directors, Korean Cancer Society 2. Member of Board of Directors, Korean Cancer Association 3. Member of Board of Directors, Korean Breast Cancer Society 4. Member of Korean Society for Molecular and Cellular Biology 5. Member of Korea Genome Organization 6. Member of the Korean Surgical Society: Vice director of General affairs ( ) 7. Member of Korean Society of Clinical Oncology 8. Active member in the American Association for Cancer Research (AACR) 9. Full member of American Society of Clinical Oncology (ASCO) Journal Editorial Commitments Associate Editor, BMC Research Notes (BioMed Central) Editorial board, International Journal of Breast Cancer (SAGE-Hindawi Access to Research) Other Scientific Commitments Organizing Committee Member, Assistant Secretary General, Global Breast Cancer Conference Organizing Committee Member, Scientific Committee, Global Breast Cancer Conference Professor of BK21 Division of Human Life Science, Seoul National University College of Medicine Organizing Committee Member, Assistant Secretary General, Global Breast Cancer Conference 2013

3 Honors & Awards 2004 Young Investigator Award, Alumni of Department of Surgery, Seoul National University Hospital 2005 Silver Award, International Cancer Symposium & the 4th Roche Asia Oncology Forum 2008 Best Research Professor 2007, Seoul National University College of Medicine GlaxoSmithKline Oncology Ethnic Research Initiative (GSK ERI) Research Grant Award ($ 100,000) 2011 Yonkang Academic Award in Surgery, The Yonkang Foundation, Korea

4 Bibliography (peer-reviewed SCI-listed journals) First or Corresponding Author 1. Kim J, Lim W, Kim EK, Kim MK, Paik NS, Jeong SS, Yoon JH, Park CH, Ahn SH, Kim LS, Han S, Nam SJ, Kang HS, Kim SI, Yoo YB, Jeong J, Kim TH, Kang T, Kim SW, Jung Y, Lee JE, Kim KS, Yu JH, Chae BJ, Jung SY, Kang E, Choi SY, Moon HG, Noh DY, Han W (Corresponding). Phase II randomized trial of neoadjuvant metformin plus letrozole versus placebo plus letrozole for estrogen receptor positive postmenopausal breast cancer (METEOR). BMC Cancer Mar 10;14(1): Kim JY, Han W (Corresponding), Moon HG, Ahn SK, Kim J, Lee JW, Kim MK, Kim T, Noh DY. Prognostic effect of preoperative Serum estradiol level in postmenopausal breast cancer. BMC Cancer Oct 27;13(1): Kim J, Han W (Corresponding), Moon HG, Ahn SK, Shin HC, You JM, Han SW, Im SA, Kim TY, Koo HR, Chang JM, Cho N, Moon WK, Noh DY. Breast density change as a predictive surrogate for response to adjuvant endocrine therapy in hormone receptor positive breast cancer. Breast Cancer Res Jul 6;14(4):R Kim J, Han W (Corresponding), Lee JW, You JM, Shin HC, Ahn SK, Moon HG, Cho N, Moon WK, Park IA, Noh DY. Factors associated with upstaging from ductal carcinoma in situ following core needle biopsy to invasive cancer in subsequent surgical excision. Breast Oct;21(5): Han W, Kim H, Ku SY, Kim SH, Choi YM, Kim JG, Moon SY. Ovarian cysts during tamoxifen use may affect the prognostic markers of premenopausal breast cancer. Gynecol Endocrinol Jan;29(1): Kim J, Han W (corresponding), Go EY, Moon HG, Ahn SK, Shin HC, You JM, Chang JM, Cho N, Moon WK, Park IA, Noh DY. Validation of a scoring system for predicting malignancy in patients diagnosed with atypical ductal hyperplasia using an ultrasound-guided core needle biopsy. J Breast Cancer Dec;15(4): Han W, Woo JH, Jeon YK, Yang SJ, Cho J, Ko E, Kim TY, Im SA, Oh DY, Park IA, Hwang KT, Moon HG, Yang KS, Noh DY. 17p12 deletion in breast cancer predicts resistance to neoadjuvant chemotherapy. Exp Ther Med Sep;2(5): Eo JS, Chun IK, Paeng JC, Kang KW, Lee SM, Han W (Corresponding), Noh DY, Chung JK, Lee DS. Imaging sensitivity of dedicated positron emission mammography in relation to tumor size. Breast Feb;21(1):66-71

5 9. Kim HJ, Han W (Corresponding), Yi OV, Shin HC, Ahn SK, Koh BS, Moon HG, You JH, Son BH, Ahn SH, Noh DY. Young age is associated with ipsilateral breast tumor recurrence after breast conserving surgery and radiation therapy in patients with HER2-positive/ER-negative subtype. Breast Cancer Res Treat Nov;130(2): Han W, Kim KY, Yang SJ, Noh DY, Kang D, Kwack K. SNP-SNP interactions between DNA repair genes were associated with breast cancer risk in a Korean population. Cancer Feb 1;118(3): Han W, Woo JH, Yu JH, Lee MJ, Moon HG, Kang D, Noh DY. Common genetic variants associated with breast cancer in korean women and differential susceptibility according to intrinsic subtype. Cancer Epidemiol Biomarkers Prev May;20(5): Chang JM, Han W (Co-first author), Moon WK, Cho N, Noh DY, Park IA, Jung EJ. Papillary Lesions Initially Diagnosed at Ultrasound-guided Vacuum-assisted Breast Biopsy: Rate of Malignancy Based on Subsequent Surgical Excision. Ann Surg Oncol Mar Kim H, Han W (Corresponding), Moon HG, Min J, Ahn SK, Kim TY, Im SA, Oh DY, Han SW, Chie EK, Ha SW, Noh DY. The value of preoperative staging chest computed tomography to detect asymptomatic lung and liver metastasis in patients with primary breast carcinoma. Breast Cancer Res Treat Apr;126(3): Bae DS, Han W (Corresponding), Moon HG, Moon WK, Cho N, Kim H, Ahn SK, Oh SK, Youn YK, Noh DY. Efficacy of Breast Ultrasonography for Detection of Local, Regional, and Contralateral Recurrence of Breast Cancer. J Breast Cancer Dec;13(4): Kim JS, Moon HG, Ahn SK, Min JW, Shin HC, Kim HS, Yeom CK, Ha SH, Chie EK, Han W (Corresponding), Noh DY. Clinicopathological Characteristics and Factors Affecting Recurrence of Ductal Carcinoma In Situ in Korean Women. J Breast Cancer Dec;13(4): Han W, Nicolau M, Noh DY, Jeffrey SS. Characterization of molecular subtypes of Korean breast cancer: an ethnically and clinically distinct population. Int J Oncol Jul;37(1): Moon HG, Han W (Co-first author), Noh DY. Comparable Survival Between pn0 Breast Cancer Patients Undergoing Sentinel Node Biopsy and Extensive Axillary Dissection: A Report From the Korean Breast Cancer Society. J Clin Oncol Apr 1;28(10):

6 18. Han W, Kang SY, Kang D, Park SK, Lee JY, Kim H, Park AK, Noh DY. Multiplex genotyping of 1107 SNPs from 232 candidate genes identified an association between IL1A polymorphism and breast cancer risk. Oncol Rep Mar;23(3): Ahn SK, Han W (Corresponding), Moon HG, et al. The Impact of Primary Tumor Resection on the Survival of Patients with Stage IV Breast Cancer. J Breast Cancer Mar; 13(1): Han W, Kang SY; The Korean Breast Cancer Society. Relationship between age at diagnosis and outcome of premenopausal breast cancer: age less than 35 years is a reasonable cut-off for defining young age-onset breast cancer. Breast Cancer Res Treat Jan;119(1): Moon HG, Han W (Co-first author), Noh DY. Underweight and Breast Cancer Recurrence and Death: A Report From the Korean Breast Cancer Society. J Clin Oncol Dec 10;27(35): Kim JH, Han W (Corresponding), Moon HG, Ko E, Lee JW, Kim EK, Park IA, Ha SW, Chie EK, Oh SK, Youn YK, Kim SW, Hwang KT, Noh DY. Factors Affecting the Ipsilateral Breast Tumor Recurrence after Breast Conserving Therapy in Patients with T1 and T2 Tumors. J Breast Cancer Dec;12(4): Jung SY, Han W (Co-first author), Lee JW, Ko E, Kim E, Yu JH, Moon HG, Park IA, Oh DY, Im SA, Kim TY, Hwang KT, Kim SW, Noh DY. Ki-67 Expression Gives Additional Prognostic Information on St. Gallen 2007 and Adjuvant! Online Risk Categories in Early Breast Cancer. Ann Surg Oncol May;16(5): Han W, Jung EM, Cho J, Lee JW, Hwang KT, Yang SJ, Kang JJ, Bae JY, Jeon YK, Park IA et al: DNA copy number alterations and expression of relevant genes in triple-negative breast cancer. Genes, chromosomes & cancer 2008, 47(6): Ahn SH, Son BH, Kim SW, Kim SI, Jeong J, Ko SS, Han W (Corresponding): Poor outcome of hormone receptor-positive breast cancer at very young age is due to tamoxifen resistance: nationwide survival data in Korea--a report from the Korean Breast Cancer Society. J Clin Oncol 2007, 25(17): Han W, Han MR, Kang JJ, Bae JY, Lee JH, Bae YJ, Lee JE, Shin HJ, Hwang KT, Hwang SE et al: Genomic alterations identified by array comparative genomic hybridization as prognostic markers in tamoxifen-treated estrogen receptorpositive breast cancer. BMC cancer 2006, 6: Han W, Kang D, Lee JE, Park IA, Choi JY, Lee KM, Bae JY, Kim S, Shin ES, Lee JE et al: A haplotype analysis of HER-2 gene polymorphisms: association

7 with breast cancer risk, HER-2 protein expression in the tumor, and disease recurrence in Korea. Clin Cancer Res 2005, 11(13): Han W, Kim SW, Park IA, Kang D, Kim SW, Youn YK, Oh SK, Choe KJ, Noh DY: Young age: an independent risk factor for disease-free survival in women with operable breast cancer. BMC cancer 2004, 4: Han W, Kang D, Park IA, Kim SW, Bae JY, Chung KW, Noh DY: Associations between breast cancer susceptibility gene polymorphisms and clinicopathological features. Clin Cancer Res 2004, 10(1 Pt 1): Han W, Kang D, Lee KM, Kim HJ, Ahn SJ, Kim SW, Chung KW, Lee ES, Noh DY: Full sequencing analysis of estrogen receptor-alpha gene polymorphism and its association with breast cancer risk. Anticancer research 2003, 23(6C): Co-author 31. Kim SJ, Chung SY, Chang JM, Cho N, Han W, Moon WK. Ultrasound screening of contralateral breast after surgery for breast cancer. Eur J Radiol Oct 7. [Epub ahead of print] 32. Kim HJ, Im SA, Keam B, Ham HS, Lee KH, Kim TY, Kim YJ, Oh DY, Kim JH, Han W, Jang IJ, Kim TY, Park IA, Noh DY. ABCB1 polymorphism as prognostic factor in breast cancer patients treated with docetaxel and doxorubicin neoadjuvant chemotherapy. Cancer Sci Nov 19. [Epub ahead of print] 33. Lee MH, Han W, Lee JE, Kim KS, Park H, Kim J, Bae SY, Shin HJ, Lee JW, Lee ES. The Clinical Impact of 21-Gene Recurrence Score on Treatment Decisions for Patients with Hormone Receptor-Positive Early Breast Cancer in Korea. Cancer Res Treat Sep 11. [Epub ahead of print] 34. Bae MS, Park SY, Song SE, Kim WH, Lee SH, Han W, Park IA, Noh DY, Moon WK. Heterogeneity of triple-negative breast cancer: mammographic, US, and MR imaging features according to androgen receptor expression. Eur Radiol Sep 16. [Epub ahead of print] 35. Kim DJ, Lee WY, Park NW, Kim GS, Lee KM, Kim J, Choi MK, Lee GH, Han W, Lee SK. Drug response of captured BT20 cells and evaluation of circulating tumor cells on a silicon nanowire platform. Biosens Bioelectron Aug 27. [Epub ahead of print] 36. Lee SA, Sung H, Han W, Noh DY, Ahn SH, Kang D. Serum adiponectin but not leptin at diagnosis as a predictor of breast cancer survival. Asian Pac J Cancer Prev. 2014;15(15):

8 37. Cha Y, Han SW, Seol H, Oh DY, Im SA, Bang YJ, Park IA, Han W, Noh DY, Kim TY. Immunohistochemical Features Associated with Sensitivity to Lapatinib-plus-Capecitabine and Resistance to Trastuzumab in HER2-positive Breast Cancer. Anticancer Res Aug;34(8): Song N, Choi JY, Sung H, Chung S, Song M, Park SK, Han W, Lee JW, Kim MK, Yoo KY, Ahn SH, Noh DY, Kang D. Heterogeneity of epidemiological factors by breast tumor subtypes in Korean women: a case-case study. Int J Cancer Aug 1;135(3): Kim TY, Lee KH, Han SW, Oh DY, Im SA, Kim TY, Han W, Kim K, Chie EK, Park IA, Kim YT, Noh DY, Ha SW, Bang YJ. A New Isolated Mediastinal Lymph Node or Small Pulmonary Nodule Arising during Breast Cancer Surveillance Following Curative Surgery: Clinical Factors That Differentiate Malignant from Benign Lesions. Cancer Res Treat Jul;46(3): Kim J, Han W, Moon HG, Ahn SK, Shin HC, You JM, Chang JM, Cho N, Moon WK, Park IA, Noh DY. Low rates of additional cancer detection by magnetic resonance imaging in newly diagnosed breast cancer patients who undergo preoperative mammography and ultrasonography. J Breast Cancer Jun;17(2): Lee SH, Moon WK, Cho N, Chang JM, Moon HG, Han W, Noh DY, Lee JC, Kim HC, Lee KB, Park IA. Shear-wave elastographic features of breast cancers: comparison with mechanical elasticity and histopathologic characteristics. Invest Radiol Mar;49(3): Park YH, Im SA, Cho EY, Ahn JH, Woo SY, Kim S, Keam B, Lee JE, Han W, Nam SJ, Park IA, Noh DY, Yang JH, Ahn JS, Im YH. Validation and Comparison of CS-IHC4 Scores with a Nomogram to Predict Recurrence in Hormone Receptor-Positive Breast Cancers. Oncology. 2014;86(5-6): Choi J, Song N, Han S, Chung S, Sung H, Lee JY, Jung S, Park SK, Yoo KY, Han W, Lee JW, Noh DY, Kang D, Choi JY. The Associations between Immunity-Related Genes and Breast Cancer Prognosis in Korean Women. PLoS One Jul 30;9(7):e Lee HC, Ko H, Seol H, Noh DY, Han W, Kim TY, Im SA, Park IA. Expression of Immunohistochemical Markers before and after Neoadjuvant Chemotherapy in Breast Carcinoma, and Their Use as Predictors of Response. J Breast Cancer Dec;16(4): Park HS, Chae BJ, Song BJ, Jung SS, Han W, Nam SJ, Youn HJ, Ko BK, Kim DW; Korea Breast Cancer Society. Effect of axillary lymph node dissection after

9 sentinel lymph node biopsy on overall survival in patients with T1 or T2 nodepositive breast cancer: report from the Korean Breast Cancer Society. Ann Surg Oncol Apr;21(4): Cho N, Im SA, Park IA, Lee KH, Li M, Han W, Noh DY, Moon WK. Breast Cancer: Early Prediction of Response to Neoadjuvant Chemotherapy Using Parametric Response Maps for MR Imaging. Radiology Aug;272(2): Lim YJ, Kim K, Chie EK, Han W, Noh DY, Ha SW. Treatment outcome of ductal carcinoma in situ patients treated with postoperative radiation therapy. Radiat Oncol J Mar;32(1): Gweon HM, Cho N, Han W, Yi A, Moon HG, Noh DY, Moon WK. Breast MR Imaging Screening in Women with a History of Breast Conservation Therapy. Radiology Aug;272(2): Kim M, Lee DW, Im J, Suh KJ, Keam B, Moon HG, Im SA, Han W, Park IA, Noh DY. Adenoid cystic carcinoma of the breast: a case series of six patients and literature review. Cancer Res Treat Jan;46(1): Ahn SH, Kim HJ, Han W, Cho J, Gong G, Jung KH, Kim SB, Son BH, Lee JW. Effect Modification of Hormonal Therapy by p53 Status in Invasive Breast Cancer. J Breast Cancer Dec;16(4): Han A, Moon HG, Kim J, Ahn SK, Park IA, Han W, Noh DY. Reliability of sentinel lymph node biopsy after neoadjuvant chemotherapy in breast cancer patients. J Breast Cancer Dec;16(4): Park B, Ma SH, Shin A, Chang MC, Choi JY, Kim S, Han W, Noh DY, Ahn SH, Kang D, Yoo KY, Park SK. Korean risk assessment model for breast cancer risk prediction. PLoS One Oct 25;8(10):e Lee SH, Moon WK, Cho N, Chang JM, Moon HG, Han W, Noh DY, Lee JC, Kim HC, Lee KB, Park IA. Shear-Wave Elastographic Features of Breast Cancers: Comparison With Mechanical Elasticity and Histopathologic Characteristics. Invest Radiol Oct 28. [Epub ahead of print] 54. Ku JL, Park SC, Kim KH, Jeon YK, Kim SH, Shin YK, Noh DY, Im SA, Bang YJ, Han W, Kim WH, Park JG. Establishment and characterization of seven human breast cancer cell lines including two triple-negative cell lines. Int J Oncol Dec;43(6): Kim KY, Han W, Noh DY, Kang D, Kwack K. Impact of genetic polymorphisms in base excision repair genes on the risk of breast cancer in a Korean population. Gene Dec 15;532(2): Bae MS, Moon WK, Cho N, Chang JM, Seo M, Park IA, Han W. Patient age and

10 tumor size determine the cancer yield of preoperative bilateral breast MRI in women with ductal carcinoma in situ. AJR Am J Roentgenol Sep;201(3): Chung S, Park SK, Sung H, Song N, Han W, Noh DY, Ahn SH, Yoo KY, Choi JY, Kang D. Association between chronological change of reproductive factors and breast cancer risk defined by hormone receptor status: results from the Seoul Breast Cancer Study. Breast Cancer Res Treat Aug;140(3): Kim JY, Han W, Moon HG, Park IA, Ahn SK, Kim J, Lee JW, Kim T, Kim MK, Noh DY. Grade of ductal carcinoma in situ accompanying infiltrating ductal carcinoma as an independent prognostic factor. Clin Breast Cancer Oct;13(5): Yom CK, Lee KM, Han W, Kim SW, Kim HS, Moon BI, Jeong KY, Im SA, Noh DY. Leptin as a potential target for estrogen receptor-positive breast cancer. J Breast Cancer Jun;16(2): Yi A, Moon WK, Cho N, Chang JM, Bae MS, Kim SJ, Han W, Park IA. Association of Tumour Stiffness on Sonoelastography with Axillary Nodal Status in T1 Breast Carcinoma Patients. Eur Radiol Jun 20. [Epub ahead of print] 61. Moon HG, Han W, Kim JY, Kim SJ, Yoon JH, Oh SJ, Yu JH, Noh DY. Effect of multiple invasive foci on breast cancer outcomes according to the molecular subtypes: a report from the Korean Breast Cancer Society. Ann Oncol Sep;24(9): Shi J, Sung H, Zhang B, Lu W, Choi JY, Xiang YB, Kim MK, Iwasaki M, Long J, Ji BT, Park SK, Zheng Y, Tsugane S, Yoo KY, Wang W, Noh DY, Han W, Kim SW, Lee MH, Lee JW, Lee JY, Shen CY, Matsuo K, Ahn SH, Gao YT, Shu XO, Cai Q, Kang D, Zheng W. New Breast Cancer Risk Variant Discovered at 10q25 in East Asian Women. Cancer Epidemiol Biomarkers Prev Jul;22(7): Lee JK, Im SA, Lee D, Kim JY, Lim Y, Lee E, Moon HG, Kim TY, Han SW, Oh DY, Lee SH, Han W, Kim DW, Kim TY, Noh DY. Efficacy of exemestane in korean patients with metastatic breast cancer after failure of nonsteroidal aromatase inhibitors. J Breast Cancer Mar;16(1): Yi A, Cho N, Im SA, Chang JM, Kim SJ, Moon HG, Han W, Park IA, Noh DY, Moon WK. Survival Outcomes of Breast Cancer Patients Who Receive Neoadjuvant Chemotherapy: Association with Dynamic Contrast-enhanced MR Imaging with Computer-aided Evaluation. Radiology Sep;268(3):

11 65. Zheng W, Han W, et al. Common genetic determinants of breast-cancer risk in East Asian women: a collaborative study of breast cancer cases and controls. Hum Mol Genet Jun 15;22(12): Keam B, Im SA, Lim Y, Han SW, Moon HG, Oh DY, Cho N, Lee SH, Han W, Moon WK, Kim DW, Kim TY, Park IA, Noh DY. Clinical Usefulness of AJCC Response Criteria for Neoadjuvant Chemotherapy in Breast Cancer. Ann Surg Oncol Jul;20(7): Bae MS, Moon WK, Chang JM, Cho N, Park SY, Won JK, Jeon YK, Moon HG, Han W, Park IA. Mammographic features of calcifications in DCIS: correlation with oestrogen receptor and human epidermal growth factor receptor 2 status. Eur Radiol Aug;23(8): Shin HC, Han W, Moon HG, Im SA, Moon WK, Park IA, Park SJ, Noh DY. Breast-Conserving Surgery After Tumor Downstaging by Neoadjuvant Chemotherapy is Oncologically Safe for Stage III Breast Cancer Patients. Ann Surg Oncol Aug;20(8): Lee KH, Keam B, Im SA, Kim TY, Han SW, Oh DY, Kim JH, Lee SH, Han W, Kim DW, Kim TY, Park IA, Noh DY, Heo DS, Bang YJ. Body mass index is not associated with treatment outcomes of breast cancer patients receiving neoadjuvant chemotherapy: korean data. J Breast Cancer Dec;15(4): Kim JY, Cho N, Koo HR, Yi A, Kim WH, Lee SH, Chang JM, Han W, Moon HG, Im SA, Noh DY, Moon WK. Unilateral Breast Cancer: Screening of Contralateral Breast by Using Preoperative MR Imaging Reduces Incidence of Metachronous Cancer. Radiology Apr;267(1): Moon HG, Yi JK, Kim HS, Lee HY, Lee KM, Yi M, Ahn S, Shin HC, Ju JH, Shin I, Han W, Noh DY. Phosphorylation of p90rsk is associated with increased response to neoadjuvant chemotherapy in ER-positive breast cancer. BMC Cancer Dec 10;12: Toi M, Benson JR, Winer EP, Forbes JF, von Minckwitz G, Golshan M, Han W, et al Preoperative systemic therapy in locoregional management of early breast cancer: highlights from the Kyoto Breast Cancer Consensus Conference. Breast Cancer Res Treat Dec;136(3): Han SA, Kim SW, Kang E, Park SK, Ahn SH, Lee MH, Nam SJ, Han W, et al. The KOHBRA Research Group and the Korean Breast Cancer Society. The prevalence of BRCA mutations among familial breast cancer patients in Korea: results of the Korean Hereditary Breast Cancer study. Fam Cancer Mar;12(1):75-81.

12 74. Yi EH, Lee CS, Lee JK, Lee YJ, Shin MK, Cho CH, Kang KW, Lee JW, Han W, Noh DY, Kim YN, Cho IH, Ye SK. STAT3-RANTES autocrine signaling is essential for tamoxifen resistance in human breast cancer cells. Mol Cancer Res Jan;11(1): Eom YH, Kim GY, Jung SS, Lee KY, Kang SB, Bae JS, Hur H, Jang YS, Lee HJ, Yoon DS, Han W, Lee IK. Present condition analysis of physician assistant in Korea. J Korean Med Sci Sep;27(9): Epub 2012 Aug Moon HG, Han W, Ahn SK, Cho N, Moon WK, Im SA, Park IA, Noh DY. Breast Cancer Molecular Phenotype and the Use of HER2-Targeted Agents Influence the Accuracy of Breast MRI After Neoadjuvant Chemotherapy. Ann Surg Jan;257(1): Kim JW, Kim JH, Im SA, Kim YJ, Han HS, Kim JS, Han SW, Jeon YK, Oh DY, Han W, Kim TY, Park IA, Noh DY, Bang YJ. ABCB1, FCGR2A, and FCGR3A Polymorphisms in Patients with HER2-Positive Metastatic Breast Cancer Who Were Treated with First-Line Taxane plus Trastuzumab Chemotherapy. Oncology. 2012;83(4): Ahn SK, Moon HG, Ko E, Kim HS, Shin HC, Kim J, You JM, Han W, Noh DY. Preoperative serum tissue polypeptide-specific antigen is a valuable prognostic marker in breast cancer. Int J Cancer Feb 15;132(4): Moon HG, Im SA, Han W, Oh DY, Han SW, Keam B, Park IA, Chang JM, Moon WK, Cho N, Noh DY. Estrogen receptor status confers a distinct pattern of response to neoadjuvant chemotherapy: implications for optimal durations of therapy : Distinct patterns of response according to ER expression. Breast Cancer Res Treat Aug;134(3): Takada M, Sugimoto M, Naito Y, Moon HG, Han W, Noh DY, Kondo M, Kuroi K, Sasano H, Inamoto T, Tomita M, Toi M. Prediction of axillary lymph node metastasis in primary breast cancer patients using a decision treebased model. BMC Med Inform Decis Mak Jun 13;12: Shin HC, Han W, Moon HG, Cho N, Moon WK, Park IA, Park SJ, Noh DY. Nomogram for predicting positive resection margins after breast-conserving surgery. Breast Cancer Res Treat Aug;134(3): Kim SJ, Chang JM, Cho N, Chung SY, Han W, Moon WK. Outcome of breast lesions detected at screening ultrasonography. Eur J Radiol Nov;81(11): Chang JM, Han W, Moon HG, Yi A, Cho N, Koo HR, Park IA, Kim SJ, Noh DY, Moon WK. Evaluation of tumor extent in breast cancer patients using real-time

13 MR navigated ultrasound: Preliminary study. Eur J Radiol Nov;81(11): Kim HC, Lee JY, Sung H, Choi JY, Park SK, Lee KM, Kim YJ, Go MJ, Li L, Cho YS, Park M, Kim DJ, Oh JH, Kim JW, Jeon JP, Jeon SY, Min H, Kim HM, Park J, Yoo KY, Noh DY, Ahn SH, Lee MH, Kim SW, Lee JW, Park BW, Park WY, Kim EH, Kim MK, Han W, Lee SA, Matsuo K, Shen CY, Wu PE, Hsiung CN, Lee JY, Kim HL, Han BG, Kang D. A genome-wide association study identifies a breast cancer risk variant in ERBB4 at 2q34: results from the Seoul Breast Cancer Study. Breast Cancer Res Mar 27;14(2):R Shin HC, Han W, Moon HG, Yom CK, Ahn SK, You JM, Kim JS, Chang JM, Cho N, Moon WK, Park IA, Noh DY. Limited Value and Utility of Breast MRI in Patients Undergoing Breast-Conserving Cancer Surgery. Ann Surg Oncol Aug;19(8): Hwang KT, Woo JW, Shin HC, Kim HS, Ahn SK, Moon HG, Han W, Park IA, Noh DY. Prognostic influence of BCL2 expression in breast cancer. Int J Cancer Oct 1;131(7):E Choi E, Park PG, Lee HO, Lee YK, Kang GH, Lee JW, Han W, Lee HC, Noh DY,Lekomtsev S, Lee H. BRCA2 Fine-Tunes the Spindle Assembly Checkpoint through Reinforcement of BubR1 Acetylation. Dev Cell Feb 14;22(2): Yom CK, Han W, Kim SW, Kim HS, Shin HC, Chang JN, Koo M, Noh DY, Moon BI. Clinical significance of annexin A1 expression in breast cancer. J Breast Cancer Dec;14(4): Keam B, Im SA, Koh Y, Han SW, Oh DY, Cho N, Kim JH, Han W, Kang KW, Moon WK, Kim TY, Park IA, Noh DY, Chung JK, Bang YJ. Predictive value of FDG PET/CT for pathologic axillary node involvement after neoadjuvant chemotherapy. Breast Cancer Feb 7. [Epub ahead of print] 90. Lee KM, Han W, Kim JB, Shin I, Ko E, Park IA, Lee DS, Oh K, Noh DY. The CD49d+/high subpopulation from isolated human breast sarcoma spheres possesses tumor-initiating ability. Int J Oncol Mar;40(3): Keam B, Im SA, Koh Y, Han SW, Oh DY, Cho N, Kim JH, Han W, Kang KW, Moon WK, Kim TY, Park IA, Noh DY, Chung JK, Bang YJ. Early metabolic response using FDG PET/CT and molecular phenotypes of breast cancer treated with neoadjuvant chemotherapy. BMC Cancer Oct 20;11(1): Kim HJ, Im SA, Keam B, Kim YJ, Han SW, Kim TM, Oh DY, Kim JH, Lee SH, Chie EK, Han W, Kim DW, Kim TY, Noh DY, Heo DS, Park IA, Bang YJ, Ha

14 SW. Clinical outcome of central nervous system metastases from breast cancer: differences in survival depending on systemic treatment. J Neurooncol Jan;106(2): Moon HG, Hwang KT, Kim JA, Kim HS, Lee MJ, Jung EM, Ko E, Han W, Noh DY. NFIB is a potential target for estrogen receptor-negative breast cancers. Mol Oncol Dec;5(6): Park SH, Moon WK, Cho N, Chang JM, Im SA, Park IA, Kang KW, Han W, Noh DY. Comparison of diffusion-weighted MR imaging and FDG PET/CT to predict pathological complete response to neoadjuvant chemotherapy in patients with breast cancer. Eur Radiol Jan;22(1): Hyung SW, Lee MY, Yu JH, Shin B, Jung HJ, Park JM, Han W, Lee KM, Moon HG, Zhang H, Aebersold R, Hwang D, Lee SW, Yu MH, Noh DY. A serum protein profile predictive of the resistance to neoadjuvant chemotherapy in advanced breast cancers. Mol Cell Proteomics Oct;10(10):M Kim K, Chie EK, Han W, Noh DY, Ha SW. Impact of delayed radiotherapy on local control in node-negative breast cancer patients treated with breastconserving surgery and adjuvant radiotherapy without chemotherapy. Tumori May-Jun;97(3): Kim K, Chie EK, Han W, Noh DY, Oh DY, Im SA, Kim TY, Bang YJ, Ha SW. Concurrent versus sequential administration of CMF chemotherapy and radiotherapy after breast-conserving surgery in early breast cancer. Tumori May-Jun;97(3): Bae MS, Han W, Koo HR, Cho N, Chang JM, Yi A, Park IA, Noh DY, Choi WS, Moon WK. Characteristics of breast cancers detected by ultrasound screening in women with negative mammograms. Cancer Sci Oct;102(10): Keam B, Im SA, Park S, Nam BH, Han SW, Oh DY, Kim JH, Lee SH, Han W, Kim DW, Kim TY, Park IA, Noh DY, Heo DS, Bang YJ. Nomogram predicting clinical outcomes in breast cancer patients treated with neoadjuvant chemotherapy. J Cancer Res Clin Oncol Sep;137(9): Chang JM, Moon WK, Cho N, Yi A, Koo HR, Han W, Noh DY, Moon HG, Kim SJ. Clinical application of shear wave elastography (SWE) in the diagnosis of benign and malignant breast diseases. Breast Cancer Res Treat Aug;129(1): Kim HS, Moon HG, Han W, Yom CK, Kim WH, Kim JH, Noh DY. COX2 overexpression is a prognostic marker for Stage III breast cancer. Breast Cancer Res Treat Apr 28.

15 102. Kim EK, Noh WC, Han W, Noh DY. Prognostic Significance of Young Age (<35 Years) by Subtype Based on ER, PR, and HER2 Status in Breast Cancer: A Nationwide Registry-Based Study. World J Surg Jun;35(6): Chang HJ, Han SW, Oh DY, Im SA, Jeon YK, Park IA, Han W, Noh DY, Bang YJ, Kim TY. Discordant human epidermal growth factor receptor 2 and hormone receptor status in primary and metastatic breast cancer and response to trastuzumab. Jpn J Clin Oncol May;41(5): Keam B, Im SA, Lee KH, Han SW, Oh DY, Kim JH, Lee SH, Han W, Kim DW, Kim TY, Park IA, Noh DY, Heo DS, Bang YJ. Ki-67 can be used for further classification of triple negative breast cancer into two subtypes with different response and prognosis. Breast Cancer Res Mar 2;13(2):R Chang JM, Moon WK, Cho N, Han W, Noh DY, Park IA, Jung EJ. Management of ultrasonographically detected benign papillomas of the breast at core needle biopsy. AJR Am J Roentgenol Mar;196(3): Jang S, Lee SH, Kim S, Lee YK, Im YH, Han W, Park HS. The Effectiveness of Silver In Situ Hybridization in Patients with Breast Cancer: A Systematic Review. J Breast Cancer Feb;14(Suppl 1):S1-S Choi HK, Cho N, Moon WK, Im SA, Han W, Noh DY. Magnetic resonance imaging evaluation of residual ductal carcinoma in situ following preoperative chemotherapy in breast cancer patients. Eur J Radiol Apr;81(4): Kim K, Chie EK, Han W, Noh DY, Oh DY, Im SA, Kim TY, Bang YJ, Ha SW. Age <40Years is an independent prognostic factor predicting inferior overall survival in patients treated with breast conservative therapy. Breast J Jan;17(1): Choi YL, Ahn SK, Bae YK, Park IA, Min JW, Lee KW, Bae JH, Han W, Choi JE, Cho EY, Kim S, Lee HS, Nam SJ, Lee JE, Lee SJ, Noh DY, Yang JH. One-step Nucleic Acid Amplification (OSNA): Intraoperative Rapid Molecular Diagnostic Method for the Detection of Sentinel Lymph Node Metastases in Breast Cancer Patients in Korean Cohort. J Breast Cancer Dec;13(4): Park SH, Moon WK, Cho N, Song IC, Chang JM, Park IA, Han W, Noh DY. Diffusion-weighted MR imaging: pretreatment prediction of response to neoadjuvant chemotherapy in patients with breast cancer. Radiology Oct;257(1): Li L, Lee KM, Han W, Choi JY, Lee JY, Kang GH, Park SK, Noh DY, Yoo KY, Kang D. Estrogen and progesterone receptor status affect genome-wide DNA methylation profile in breast cancer. Hum Mol Genet Nov 1;19(21):

16 112. Yang JJ, Park SK, Cho LY, Han W, Park B, Kim H, Lee KS, Hahn SK, Cho SI, Ahn SH, Noh DY; Korean Breast Cancer Society. Cost-effectiveness analysis of 5 years of postoperative adjuvant tamoxifen therapy for Korean women with breast cancer: retrospective cohort study of the Korean breast cancer society database. Clin Ther Jun;32(6): Yhim HY, Han SW, Oh DY, Han W, Im SA, Kim TY, Kim YT, Noh DY, Chie EK, Ha SW, Park IA, Bang YJ. Prognostic factors for recurrent breast cancer patients with an isolated, limited number of lung metastases and implications for pulmonary metastasectomy. Cancer Jun 15;116(12): Moon HG, Han W, Lee JW, Ko E, Kim EK, Yu JH, Jung SY, Lyou CY, Moon WK, Hwang KT, Noh DY. Limitations of Conventional Contrast-enhanced MRI in Selecting Sentinel Node Biopsy Candidates among DCIS Patients. J Breast Cancer Jun;13(2): Peng J, Zhu J, Bergamaschi A, Han W, Noh DY, Pollack JR, Wang P. Regularized multivariate regression for identifying master predictors with application to integrative genomics study of breast cancer. The Annals of Applied Statistics. 2010;4(1): Moon HG, Han W, Noh DY. Reply to M.H. Tan et al. J Clin Oncol Apr 10;28(11): e Hwang KT, Chung JK, Han W, et al. COL18A1 as the Candidate Gene for the Prognostic Marker of Breast Cancer According to the Analysis of the DNA Copy Number Variation by Array CGH. J Breast Cancer 2010 March; 13(1): Kim K, Chie EK, Han W, Noh DY, Park IA, Oh DY, Im SA, Kim TY, Bang YJ, Ha SW. Prognostic Value of p53 and bcl-2 Expression in Patients Treated with Breast Conservative Therapy. J Korean Med Sci Feb;25(2): Cho N, Moon WK, Han W, Park IA, Cho J, Noh DY. Preoperative Sonographic classification of axillary lymph nodes in patients with breast cancer: node-to-node correlation with surgical histology and sentinel node biopsy results. AJR Am J Roentgenol Dec;193(6): Chang JM, Moon WK, Cho N, Han W, Noh DY, Park IA, Jung EJ. Risk of carcinoma after subsequent excision of benign papilloma initially diagnosed with an ultrasound (US)-guided 14-gauge core needle biopsy: a prospective observational study. Eur Radiol May;20(5): Lim KH, Oh DY, Chie EK, Han W, Im SA, Kim TY, Park IA, Noh DY, Ha SW, Bang YJ. Metaplastic Breast Carcinoma: Clinicopathologic Features and Prognostic Value of Triple Negativity. Jpn J Clin Oncol Feb;40(2): Bocanegra M, Bergamaschi A, Kim YH, Miller MA, Rajput AB, Kao J, Langerød

17 A, Han W, Noh DY, Jeffrey SS, Huntsman DG, Børresen-Dale AL, Pollack JR. Focal amplification and oncogene dependency of GAB2 in breast cancer. Oncogene Feb 4;29(5): Kim JB, Yu JH, Ko E, Lee KW, Song AK, Park SY, Shin I, Han W, Noh DY. The alkaloid Berberine inhibits the growth of Anoikis-resistant MCF-7 and MDA- MB-231 breast cancer cell lines by inducing cell cycle arrest. Phytomedicine May;17(6): Chie EK, Kim K, Han W, Noh DY, Oh DY, Im SA, Kim TY, Bang YJ, Ha SW. Results of breast-conserving therapy for multifocal or multicentric breast cancers. Asia-Pacific J Clin Oncol 2009 Sep;5(3): Kim K, Chie EK, Han W, Noh DY, Oh DY, Im SA, Kim TY, Bang YJ, Ha SW. Prognostic Factors Affecting the Outcome of Salvage Radiotherapy for Isolated Locoregional Recurrence After Mastectomy. Am J Clin Oncol Feb 4;29(5): Seong MW, Cho SI, Noh DY, Han W, Kim SW, Park CM, Park HW, Kim SY, Kim JY, Park SS. Low contribution of BRCA1/2 genomic rearrangement to highrisk breast cancer in the Korean population. Fam Cancer. 2009;8(4): Seong MW, Cho S, Noh DY, Han W, Kim SW, Park CM, Park HW, Kim S, Kim J, Park S. Comprehensive mutational analysis of BRCA1/BRCA2 for Korean breast cancer patients: evidence of a founder mutation. Clin Genet Aug;76(2): Han SA, Park SK, Ahn SH, Han W, et al: The Breast and Ovarian Cancer Risks in Korea Due to Inherited Mutations in BRCA1 and BRCA2: A Preliminary Report. J Breast Cancer 2009 June; 12(2): Yi JK, Chang JW, Han W, Lee JW, Ko E, Kim DH, Bae JY, Yu J, Lee C, Yu MH, Noh DY. Autoantibody to Tumor Antigen, Alpha 2-HS Glycoprotein: A Novel Biomarker of Breast Cancer Screening and Diagnosis. Cancer Epidemiol Biomarkers Prev May;18(5): Lee JY, Park AK, Lee KM, Park SK, Han S, Han W, Noh DY, Yoo KY, Kim H, Welch R, Chanock SJ, Rothman N, Kang D. Candidate gene approach evaluates association between innate immunity genes and breast cancer risk in Korean women. Carcinogenesis Sep;30(9): Keam B, Im SA, Kim HJ, Oh DY, Kim JH, Lee SH, Chie EK, Han W, Kim DW, Cho N et al: Clinical significance of axillary nodal ratio in stage II/III breast cancer treated with neoadjuvant chemotherapy. Breast cancer research and treatment 2009 Jul;116(1):

18 132. Moon HG, Han W, Lee JW, Ko E, Kim EK, Yu JH, Kang SY, Moon WK, Cho N, Park IA, Oh DY, Han SW, Im SA, Noh DY. Age and HER2 expression status affect MRI accuracy in predicting residual tumor extent after neo-adjuvant systemic treatment. Ann Oncol Apr;20(4): Ko E, Han W, Cho J, Lee JW, Kang SY, Jung SY, Kim EK, Hwang KT, Noh DY. Fibrin glue reduces the duration of lymphatic drainage after lumpectomy and level II or III axillary lymph node dissection for breast cancer: a prospective randomized trial. J Korean Med Sci Feb;24(1): Kim Y, Park SK, Han W, Kim DH, Hong YC, Ha EH, Ahn SH, Noh DY, Kang D, Yoo KY. Serum High-Density Lipoprotein Cholesterol and Breast Cancer Risk by Menopausal Status, Body Mass Index, and Hormonal Receptor in Korea. Cancer Epidemiol Biomarkers Prev Feb;18(2): Park SY, Kim KS, Lee TG, Park SS, Kim SM, Han W, Noh DY, Kim SW: The accuracy of preoperative core biopsy in determining histologic grade, hormone receptors, and human epidermal growth factor receptor 2 status in invasive breast cancer. American journal of surgery 2009 Feb;197(2): Bergamaschi A, Kim YH, Kwei KA, La Choi Y, Bocanegra M, Langerød A, Han W, Noh DY, Huntsman DG, Jeffrey SS, Børresen-Dale AL, Pollack JR. CAMK1D amplification implicated in epithelial-mesenchymal transition in basallike breast cancer. Mol Oncol Dec;2(4): Horlings HM, Bergamaschi A, Nordgard SH, Kim YH, Han W, Noh DY, Salari K, Joosse SA, Reyal F, Lingjaerde OC et al: ESR1 gene amplification in breast cancer: a common phenomenon? Nature genetics 2008, 40(7): Hwang KT, Han W, Cho J, Lee JW, Ko E, Kim EK, Jung SY, Jeong EM, Bae JY, Kang JJ et al: Genomic copy number alterations as predictive markers of systemic recurrence in breast cancer. International journal of cancer 2008, 123(8): Ko SS; Korean Breast Cancer Society. Chronological changing patterns of clinical characteristics of Korean breast cancer patients during 10 years ( ) using nationwide breast cancer registration on-line program: biannual update. J Surg Oncol Oct 1;98(5): Lee JW, Han W, Ko E, Cho J, Kim EK, Jung SY, Cho N, Moon WK, Park IA, Noh DY: Sonographic lesion size of ductal carcinoma in situ as a preoperative predictor for the presence of an invasive focus. Journal of surgical oncology 2008, 98(1): Ko E, Han W, Lee JW, Cho J, Kim EK, Jung SY, Kang MJ, Moon WK, Park IA,

19 Kim SW et al: Scoring system for predicting malignancy in patients diagnosed with atypical ductal hyperplasia at ultrasound-guided core needle biopsy. Breast cancer research and treatment 2008, 112(1): Kim JB, Ko E, Han W, Lee JE, Lee KM, Shin I, Kim S, Lee JW, Cho J, Bae JY et al: CD24 cross-linking induces apoptosis in, and inhibits migration of, MCF-7 breast cancer cells. BMC cancer 2008, 8: Kim JB, Ko E, Han W, Shin I, Park SY, Noh DY. Berberine Diminishes the Side Population and ABCG2 Transporter Expression in MCF-7 Breast Cancer Cells. Planta Med. 2008;74(14): Cho J, Han W, Noh DY: What Is the Best? Annals of surgical oncology 2008;15(11): Cho J, Han W, Lee JW, Ko E, Kang SY, Jung SY, Kim EK, Moon WK, Cho N, Park IA et al: A scoring system to predict nonsentinel lymph node status in breast cancer patients with metastatic sentinel lymph nodes: a comparison with other scoring systems. Annals of surgical oncology 2008, 15(8): Kim JB, Lee KM, Ko E, Han W, Lee JE, Shin I, Bae JY, Kim S, Noh DY: Berberine inhibits growth of the breast cancer cell lines MCF-7 and MDA-MB Planta medica 2008, 74(1): Kim SH, Son BH, Hwang SY, Han W, Yang JH, Lee S, Yun YH: Fatigue and depression in disease-free breast cancer survivors: prevalence, correlates, and association with quality of life. Journal of pain and symptom management 2008, 35(6): Han S, Lee KM, Choi JY, Park SK, Lee JY, Lee JE, Noh DY, Ahn SH, Han W, Kim DH et al: CASP8 polymorphisms, estrogen and progesterone receptor status, and breast cancer risk. Breast cancer research and treatment 2008, 110(2): Rhee J, Han SW, Oh DY, Kim JH, Im SA, Han W, Park IA, Noh DY, Bang YJ, Kim TY. The clinicopathologic characteristics and prognostic significance of triple-negativity in node-negative breast cancer. BMC Cancer Oct 23;8: Chung YS, Choe JH, Han W, et al. Title: Acute suppurative thyroiditis in a patient with aplastic anemia. Infections in medicine 2008, 25(7): Bae JY, Ahn SJ, Han W, Noh DY: Peroxiredoxin I and II inhibit H2O2-induced cell death in MCF-7 cell lines. Journal of cellular biochemistry 2007, 101(4): Hwang KT, Han W, Bae JY, Hwang SE, Shin HJ, Lee JE, Kim SW, Min HJ, Noh DY: Downregulation of the RUNX3 gene by promoter hypermethylation and

20 hemizygous deletion in breast cancer. Journal of Korean medical science 2007, 22 Suppl:S Lee MK, Son BH, Hwang SY, Han W, Yang JH, Lee S, Yun YH: Factors affecting health-related quality of life in women with recurrent breast cancer in Korea. Qual Life Res 2007, 16(4): Lee KM, Choi JY, Lee JE, Noh DY, Ahn SH, Han W, Yoo KY, Hayes RB, Kang D: Genetic polymorphisms of NOS3 are associated with the risk of invasive breast cancer with lymph node involvement. Breast cancer research and treatment 2007, 106(3): Lee KH, Im SA, Oh DY, Lee SH, Chie EK, Han W, Kim DW, Kim TY, Park IA, Noh DY et al: Prognostic significance of bcl-2 expression in stage III breast cancer patients who had received doxorubicin and cyclophosphamide followed by paclitaxel as adjuvant chemotherapy. BMC cancer 2007, 7: Kim HJ, Kim JB, Lee KM, Shin I, Han W, Ko E, Bae JY, Noh DY: Isolation of CD24(high) and CD24(low/-) cells from MCF-7: CD24 expression is positively related with proliferation, adhesion and invasion in MCF-7. Cancer letters 2007, 258(1): Keam B, Im SA, Kim HJ, Oh DY, Kim JH, Lee SH, Chie EK, Han W, Kim DW, Moon WK et al: Prognostic impact of clinicopathologic parameters in stage II/III breast cancer treated with neoadjuvant docetaxel and doxorubicin chemotherapy: paradoxical features of the triple negative breast cancer. BMC cancer 2007, 7: Chung YS, Choe JH, Kang KH, Kim SW, Chung KW, Park KS, Han W, Noh DY, Oh SK, Youn YK: Endoscopic thyroidectomy for thyroid malignancies: comparison with conventional open thyroidectomy. World journal of surgery 2007, 31(12): ; discussion Choe JH, Kim SW, Chung KW, Park KS, Han W, Noh DY, Oh SK, Youn YK: Endoscopic thyroidectomy using a new bilateral axillo-breast approach. World journal of surgery 2007, 31(3): Ahn SH, Son BH, Yoon KS, Noh DY, Han W, Kim SW, Lee ES, Park HL, Hong YJ, Choi JJ et al: BRCA1 and BRCA2 germline mutations in Korean breast cancer patients at high risk of carrying mutations. Cancer letters 2007, 245(1-2): Kapp AV, Jeffrey SS, Langerod A, Borresen-Dale AL, Han W, Noh DY, Bukholm IR, Nicolau M, Brown PO, Tibshirani R: Discovery and validation of breast cancer subtypes. BMC genomics 2006, 7: Choi JY, Lee KM, Noh DY, Ahn SH, Lee JE, Han W, Jang IJ, Shin SG, Yoo KY,

21 Hayes RB et al: Genetic polymorphisms of enos, hormone receptor status, and survival of breast cancer. Breast cancer research and treatment 2006, 100(2): Jessani N, Niessen S, Wei BQ, Nicolau M, Humphrey M, Ji Y, Han W, Noh DY, Yates JR, 3rd, Jeffrey SS et al: A streamlined platform for high-content functional proteomics of primary human specimens. Nature methods 2005, 2(9): Lee KM, Choi JY, Park SK, Chung HW, Ahn B, Yoo KY, Han W, Noh DY, Ahn SH, Kim H et al: Genetic polymorphisms of ataxia telangiectasia mutated and breast cancer risk. Cancer Epidemiol Biomarkers Prev 2005, 14(4): Lee JE, Park SS, Han W, Kim SW, Shin HJ, Choe KJ, Oh SK, Youn YK, Noh DY, Kim SW: The clinical use of staging bone scan in patients with breast carcinoma: reevaluation by the 2003 American Joint Committee on Cancer staging system. Cancer 2005, 104(3): Lee JE, Kim HJ, Bae JY, Kim SW, Park JS, Shin HJ, Han W, Kim SW, Kang KS, Noh DY: Neogenin expression may be inversely correlated to the tumorigenicity of human breast cancer. BMC cancer 2005, 5: Choi JY, Lee KM, Park SK, Noh DY, Ahn SH, Chung HW, Han W, Kim JS, Shin SG, Jang IJ et al: Genetic polymorphisms of SULT1A1 and SULT1E1 and the risk and survival of breast cancer. Cancer Epidemiol Biomarkers Prev 2005, 14(5): Bae JY, Ahn SJ, Lee JE, Kim JE, Han MR, Han W, Kim SW, Shin HJ, Lee SJ, Park D et al: BetaPix-a enhances the activity of phospholipase Cgamma1 by binding SH3 domain in breast cancer. Journal of cellular biochemistry 2005, 94(5): Sun JM, Han W, Im SA, Kim TY, Park IA, Noh DY, Heo DS, Bang YJ, Choe KJ, Kim NK: A combination of HER-2 status and the St. Gallen classification provides useful information on prognosis in lymph node-negative breast carcinoma. Cancer 2004, 101(11): Lee SA, Kang D, Nishio H, Lee MJ, Kim DH, Han W, Yoo KY, Ahn SH, Choe KJ, Hirvonen A et al: Methylenetetrahydrofolate reductase polymorphism, diet, and breast cancer in Korean women. Experimental & molecular medicine 2004, 36(2): Lee JE, Chung KW, Han W, Kim SW, Kim SW, Shin HJ, Bae JY, Noh DY: Effect of estrogen, tamoxifen and epidermal growth factor on the transcriptional regulation of vascular endothelial growth factor in breast cancer cells. Anticancer research 2004, 24(6):

22 172. Lee EO, Ahn SH, You C, Lee DS, Han W, Choe KJ, Noh DY: Determining the main risk factors and high-risk groups of breast cancer using a predictive model for breast cancer risk assessment in South Korea. Cancer nursing 2004, 27(5): Choi JY, Hamajima N, Tajima K, Yoo KY, Yoon KS, Park SK, Kim SU, Lee KM, Noh DY, Ahn SH, Han W, et al: hogg1 Ser326Cys polymorphism and breast cancer risk among Asian women. Breast cancer research and treatment 2003, 79(1): Choi JY, Abel J, Neuhaus T, Ko Y, Harth V, Hamajima N, Tajima K, Yoo KY, Park SK, Noh DY, Han W et al: Role of alcohol and genetic polymorphisms of CYP2E1 and ALDH2 in breast cancer development. Pharmacogenetics 2003, 13(2): Ahn SJ, Yoon MS, Hyuk S, Han W, Yoon YD, Han JS, Noh DY: Phospholipase C-protein kinase C mediated phospholipase D activation pathway is involved in tamoxifen induced apoptosis. Journal of cellular biochemistry 2003, 89(3): Bibliography (peer-reviewed Korean journals) 1. Han SA, Kim S, Kang E, Ha TH, Kim JH, Yang EJ, Lim JY, Han W, Noh DY, Kim SW. Evaluation of Psychosocial Impact and Quality of Life in BRCA Mutation Family. J Genet Med Jun;7(1): Eui Kyu Chie, Kyubo Kim, Jin-Hwa Choi, Na-Young Jang, Wonshik Han, et al. Results of Breast Conserving Surgery and Subsequent Postoperative Radiotherapy for Cases of Breast Cancer. Journal of KOSTRO 2008;26(3): Hyoungsuk Ko, Hyesil Seol, Wook Youn Kim, Seock-Ah Im, Wonshik Han, et al. Ongoing debates in the assessment of the HER2 status in breast cancer: A comparative analysis by immunohistochemistry and FISH using original FDA and ASCO/CAP guidelines. Basic and Applied Pathology 2008; 1: Kim KS, Han SA, Kim S, Lim JY, Kim SM, Jang M, Han W, Noh DY, Kim SW. The Axillary Arch of Langer (Axillopectoral Muscle): A Case Report. J Breast Cancer Jun;11(2): Chung YS, Choe JH, Lee KE, Park WS, Kim HY, Han W, Noh DY, Oh SK, Youn YK. Detection of BRAF Mutation on Fine Needle Aspiration Biopsy Specimens Using the Colorimetric Mutation Detection Method. J Korean Surg Soc Jan;74(1): Ha HK, Han W, Ko E, Kang SY, Lee JW, Cho J, Jung SY, Kim EK, Oh SK, Youn

23 YK, Noh DY. Toremifene as an Adjuvant Hormone Therapy for Estrogen Receptor Positive early Breast Cancer: Therapeutic Efficacy and Effect on Endometrium. J Breast Cancer Dec;10(4): Lee JW, Han W, Ko E, Cho J, Jung SY, Kim EK, Keam B, Im SA, Lee HC, Park IA, Oh SK, Youn YK, Kim SW, Hwang KT, Noh DY. Alteration of Estrogen Receptor, Progesterone Receptor, and HER-2 Expression in Breast Cancer after Neoadjuvant Chemotherapy. J Breast Cancer Sep;10(3): Cho J, Han W, Ko E, Lee JW, Jung SY, Kim EK, Lee HC, Park IA, Oh SK, Youn YK, Kim SW, Hwang KT, Noh DY. The Clinical and Histopathological Characteristics of Male Breast Cancer Patient. J Korean Breast Cancer Soc Sep;10(3): Lee JE, Ko E, Bin Kim J, Lee KM, Han W, Noh DY. Breast cancer stem cells: Changing therapeutic paradigm? TISSUE ENGINEERING AND REGENERATIVE MEDICINE 2007; 4(3): Kim SW, Han W, Jeong J, Park HK, Noh WC, Lee ES, Kim JS, Noh DY, Park CH, Han SH. The Policy Proposal for Effective Prevention and Management of Breast Cancer. J Breast Cancer Dec;9(4): Hwang SE, Moon WK, Cho N, Han W, Kim SW, Shin HJ, Hwang KT, Lee JE, Youn YK, Oh SK, Noh DY. Preoperative Evaluation of Lymph Node Metastasis with Using Ultrasonography for Examining the Axilla in Early Stage Breast Cancer. J Breast Cancer Jun;9(2): Lee JE, Shin HJ, Hwang SE, Hwang KT, Oh SK, Youn YK, Noh DY, Kim SW, Han W. A case of Breast Gigantism in a Patient with Wilson's Disease treated by Penicillamine. J Breast Cancer Mar;9(1): Shin HJ, Han W, Kim SW, Hwang KT, Hwang SE, Lee JE, Kim SW, Youn YK, Oh SK, Choe KJ, Noh DY. Postoperative Survival and Prognostic Factors in Breast Cancer : a Single Center Analysis of 4,063 Cases. J Breast Cancer Mar;9(1): Jung SY, Han W, Shin HJ, Lee JE, Hwang KT, Hwang SE, Oh SK, Youn YK, Kim SW, Noh DY. Usefulness of Ki-67 as a prognostic factor in lymph nodenegative breast cancer. J Breast Cancer Mar;9(1): Park JH, Han W, Kim SW, Lee JE, Shin HJ, Kim SW, Choe KJ, Oh SK, Youn YK, Noh DY. The Clinicopathologic Characteristics of 38 Metaplastic Carcinomas of the Breast. J Breast Cancer Jun;8(2): Cha JH, Moon WK, Cho N, Kim SM, Kim SJ, Park SH, Cho KS, Koh YH, Noh DY, Han W, Park IA. Ultrasound Assessment of Invasive Breast Cancer: