EVIDENCED-BASED DIETS AND THEIR ROLE IN HEALTHCARE

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1 EVIDENCED-BASED DIETS AND THEIR ROLE IN HEALTHCARE MERCY MEDICAL CENTER OUTPATIENT REGISTERED DIETITIANS TERRI CLARK AND KRISTEN DECKER

2 REGISTERED DIETITIAN VS NUTRITIONIST 4 year degree, minimum + accredited internship program Successful completion of certification exam + licensure within state Accrediting body Academy of Nutrition and Dietetics

3 FOUNDATIONS FOR PROPER NUTRITION Healthful eating of a variety of foods, focusing on whole foods and portion control Individualization of nutrition plan based on patient goals and lifestyle Nutrition Tracking and Food Logs

4 OBJECTIVES AND OUTLINE Evidence-Based Diet Overview Mediterranean Diet Ketogenic and Low Carbohydrate Diets Low FODMAP Diet Mercy Outpatient Nutrition Services Resources for physicians and patients

5 Wine in moderation Meats & Sweets Less often Poultry, Eggs, Cheese and Yogurt Moderate portions, daily to weekly Mediterranean Diet Pyramid Drink water Fish and Seafood Often, at least twice a week Fruits, Vegetables, Grains (mostly whole), Olive oil, Beans, Nuts, Legumes, Seeds, Herbs and Spices Base every meal on these foods Be physically active; Enjoy meals with others 2009 Oldways Preservation and Exchange Trust

6 MEDITERRANEAN DIET POTENTIAL BENEFITS Improvement of the following conditions: Depression, Alzheimer's and healthier brain function High blood pressure Lowering of blood glucose and cholesterol values Decreased stroked risk and other cardiovascular risk factors Weight loss

7 PATTERNS OF PLANT AND ANIMAL PROTEIN INTAKE AND CARDIOVASCULAR MORTALITY Adventist Health Study-2 assessed diets of 81,337 men and women from , using food frequency reports. (1) An average of 9.9 years for follow up was noted among participants in this time 2,276 deaths were identified as due to cardiovascular disease. After controlling for several potential confounders, an 18 gram increase in animal protein intake (~1/4 total protein intake) was significantly associated with a higher risk of CVD mortality There was no significant association found between plant protein intake and CVD mortality Healthy diets can be advocated to prefer lower amounts of protein from meat and higher intakes of protein from plant sources, such as nuts and seeds.

8 BENEFITS OF MEDITERRANEAN DIET Diets that emphasize whole, fresh foods and limit sugars, saturated fats and sodium may prevent and manage obesity and cardiovascular diseases. (1) The body of research on preventing diabetes-related chronic diseases also supports the benefits of a plant-based eating pattern. (2) The healthfulness of a plant-based diet is emphasized with regards to the American Institute of Cancer Research guidelines. (3)

9 DKK1 Ketogenic Diet Very Low Carbohydrate, High Fat Ketogenic Diet guidelines are often specific and restrictive with carbohydrates, keeping totals to very low percentages of calories (often between grams of total carbohydrate). SAD (Standard American Diet) Ketogenic Diet

10 Slide 9 DKK1 Decker, Kristen K., 1/14/2019

11 KETOGENIC DIET BASICS Healthy fats and low carbohydrate vegetables are meant to be the foundation: Olive oil, avocados, olives, coconut oil, nuts and seeds Leafy greens, cucumbers, celery, bell peppers, broccoli, cauliflower, cabbage, squash Saturated fats (butter, bacon, coconut oil, high fat meats) are allowed in moderation but not intended to be emphasized as the only source of fat Grains, legumes/beans and fruits are essentially avoided during this lowest carbohydrate phase as well as any processed foods or drinks (cereals, breads, crackers, tortillas, pasta, soda, etc.)

12 KETOGENIC DIET Benefits Potential medication weaning (blood sugar management meds) Improvements in mood, sleep, alertness Weight loss Improved blood pressure, lipid panel, Hemoglobin A1C Potential Side Effects Hypoglycemia Lipid abnormalities (although some research supports improvements) Low electrolytes Gastrointestinal Pancreatitis

13 LOW CARBOHYDRATE DIETS very low-carbohydrate/ ketogenic diet: 20 to 50 g/day or <10% of total kcal; low-carbohydrate diet: <150 g/day or <26% of total kcal; moderate-carbohydrate diet: >130 g/day or 26% to 45% of total kcal; high-carbohydrate diet: >225 g/day or >45% of total kcal.

14 LOW CARBOHYDRATE DIETS For weight loss, a lower carbohydrate goal of grams per day generally results in faster and more sustainable weight loss, for many. For comparison: The USDA dietary guidelines recommend grams of carbohydrates per day on a 2,000 calorie diet, which is 45-65% of daily calories. More research supports reducing the level to less than 100 grams daily to lower postprandial glucose response, reduce serum triglyceride synthesis, increase HDL, promote satiety. (4) For those initially using the ketogenic diet, transitioning to a low carbohydrate diet can be a great end goal and easier lifestyle to maintain long term.

15 KETOGENIC AND LOW CARBOHYDRATE DIETS COMMON AND EFFECTIVE USES: Epilepsy Reflux/ Heartburn Polycystic Ovarian Syndrome Diabetes Weight Loss THE CHALLENGES: Adherence Accountability and support dietitian, doctor, family, friends, online Quality resources websites, recipes, products and substitutions

16 RESEARCH SUPPORTING LOW CARBOHYDRATE DIETS Data from 1,141 obese patients, some with type 2 diabetes, showed that following a very low-carb diet for between 3-36 months resulted in significant improvements in: Waist circumference, blood pressure, triglycerides, fasting glucose, A1C, insulin levels and C-reactive protein levels as well as an increase in heart-protective HDL cholesterol (5) A long-term study published in August 2010 (Annals of Internal Medicine) involving 115 participants, average age 58, mean BMI 34.6 and an A1C of 7.3% (5,8) Compared the effects of a high fat, low-carb (14% daily calories) diet and a low-fat, high-carbohydrate (53% calories) The results showed that although weight loss was comparable in both groups, the low carb group benefited from greater reductions in use of glucose-lowering medication, blood pressure and triglycerides and larger increases in their HDL cholesterol.

17 RESEARCH 34 randomized adults who were overweight with an A1c greater than 6% in a 12-month study using a very low-carb/ketogenic diet (20 g to 50 g carbohydrate, excluding fiber) or a moderatecarbohydrate (45% to 50% of total kcal), calorie-restricted, low-fat diet with equal retention of 85%. (7) Both groups received education and support separately throughout the study. At 12 months, participants in the very low-carb/ketogenic diet group had: Greater decreases in A1c (from 6.6% to 6.1%) compared with those in the moderate-carbohydrate group (6.9% to 6.7%) Lost more weight (18# average loss vs. 3.75#) Had larger reductions or discontinuation of glucose-lowering medications

18 KETOGENIC AND LOW CARBOHYDRATE FINAL THOUGHTS Consistent across most low-carb studies is that despite the higher total and saturated fat content, individuals tend to benefit from lower triglycerides, higher HDL cholesterol, lower C- reactive protein levels, and better glycemic control which all translate to lower CVD risk. Total LDL cholesterol values usually remain stable but shifts are usually seen in their particle size from the small and dense pattern B to the larger, less harmful pattern A., as explained in August 2005 issue of Nutrition and Metabolism (5) Kidney health also shouldn t be a concern for most individuals with type 2 diabetes and normal renal function. It s important to remember that the low-carb diets studied in the scientific literature aren t necessarily high-protein diets but rather higher-fat diets.

19 CONSENSUS? Ketogenic and low carb diets ARE effective for improvements in diabetes and heart disease risk factors, as well as weight loss These diets are as or less effective than others if the focus is long term weight loss, as all diet and lifestyle changes must be continued to maintain results They may not be advised for someone with renal disease or specific CVD markers The beneficial role of a dietitian to educate and support patients throughout this process, in collaboration with physicians, is backed by research

20 MERCY OUTPATIENT NUTRITION SERVICES 15 + YEARS AT MERCY (LOCATED IN WOMEN S CENTER) Medical Nutrition Therapy Bariatric Program Mercy Weight Loss Program Educational Speaking Media

21 NUTRITION CONSULTATIONS Motivational interviewing and assessing readiness for lifestyle changes Goal setting Self monitoring food logs, water intake, activity, weekly weights Structured meal plans, portion control and suggested products, as needed Problem solving and additional resources

22 The FODMaP Diet promoting gastrointestinal health with diet

23 FODMaPs Fermentable Oligosaccharides, Disaccharides, Monosaccharides and Polyols Slowly absorbed, highly osmotic, and rapidly fermented short- chain carbohydrates Found in both natural and synthetic foods and beverages. Education on elimination diet of foods high in FODMAPs, gain relief from GI symptoms and eventually add back in foods tolerated.

24

25 WHO BENEFITS ON THE FODMAPS DIET Patients with - Irritable Bowel Syndrome - Fructose Intolerance - Non-Celiac Wheat Sensitivity Usual Symptoms Abdominal bloating Abdominal pain Abnormal bowel habits Constipation / diarrhea Excessive gas Lack of BM satisfaction Passage of mucous Fatigue

26 LOW FODMAP DIETARY APPROACH Implemented by a FODMAP knowledgeable dietitian Elimination Phase (2-6 week) Reintroduction phase (2-4 months - to lifetime)

27 RESEARCH SUPPORTING FODMAPS DIET Over the past 10 years, the magnitude of evidence for the mechanisms and clinical efficacy of the low FODMAP diet has surpassed any other dietary intervention for IBS, except probiotics. Staudacher et al (2017) Gut. Effective treatment for many patients diagnosed with IBS and associated symptoms (75-85% of IBS patients experienced significant, sustainable relief of their IBS symptoms). Australian research at Monash University Numerous clinical studies have found evidence that a low FODMaP diet alleviate symptoms associated with digestive discomfort in people with IBS. Gibson PR, Shepherd SJ ;AmJ Gastroenterol.(2012)

28 MERCY LOW FODMAPS CLASS Starting sometime in 2019 (hopefully this Spring) Small Classes (2-4 participants) 10 weeks in length with 4 group visits during this duration. Cost? unsure at this time. Our goal is to give the patient a clear understanding of foods to eliminate and eventually re-introduce foods to provide variety of tolerated foods and to avoid nutritional deficiencies.

29 MERCY BARIATRIC SURGERY PROGRAM AND NUTRITION SERVICES

30 MERCY BARIATRIC SURGERY PROGRAM ROLE OF THE DIETITIAN PRE OPERATIVELY Meet Monthly Promote Safe and Steady weight loss through nutrition education / behavior change Emphasis on hydration Micronutrient education Encourage daily exercise POST OPERATIVELY Educate appropriate post op diets Liquid, puree, soft, general Ensure fluid and protein requirements are met. Encourage continued new eating habits Ensure MVI / min supplements and Micronutrient deficiencies are avoided

31 MERCY WEIGHT LOSS PROGRAM Started program in 2011 Led by a dietitian with a focus on evidenced based nutrition Duration: 12 Weeks Class Size: 6 to 2 participants Location: Diabetes Center or Main Campus Hospital Cost: $ (Self Pay) Portions Food Groups Mindful Eating Meal Planning Stimulus Control Support Network Eating Out

32 MERCY WEIGHT LOSS PROGRAM STATISTICS 70% program retention rate 285 start / 270 completed class Average weight loss 8.6 lbs. (3.7%) within 12 weeks Several participants with 20+ lbs. lost. ** What was most weight a participant lost? 32#! **

33 MERCY WEIGHT LOSS PROGRAM WHAT ARE PEOPLE SAYING I now have the tools I need to be successful with food choices and lifestyle changes. I lost enough weight to gain back confidence in myself and to try a lot of other things, but I think the support and how I was taught was what the big benefit. I would recommend this program to anyone. I actually looked forward to the class every week. Changed a lot of habits to a healthier lifestyle and lost approx. 27lbs! Make better choices, realize that weight loss is lifetime of healthy eating, not a diet.

34 MERCY WEIGHT LOSS PROGRAM HOW DID YOU HEAR ABOUT THE PROGRAM Website ( Physician referrals / recommendations Mercy Mailers and flyers Word of Mouth

35 MERCY DIETITIANS OFFICE LOCATED IN THE WOMEN S CENTER Experts in nutrition We meet the patient s where they are at Focus on education and wellness Timely appointments to help patient grasp concepts Updated and evidence-based nutrition handouts / resources

36 REFERRING A PATIENT EPIC PROCESS OUTLINE Plan Meds/Orders Type in: Ambulatory referral for Nutrition Services Details open order Expected date at least 1 week out from current date Reason for referral MNT Medicare reimbursement, must be associated with diagnosis Diagnoses: Obesity & morbid obesity Diabetes Hyperlipidemia Food Allergies Irritable Bowel Syndrome Celiac Disease Mercy Outpatient Nutrition Office:

37 RESOURCES Keto and Low Carb: Mediterranean FODMAPs

38 REFERENCES 1. International Journal of Epidemiology, Volume 47, Issue 5, 1 October 2018, Pages , 2. Franz MJ, MacLeod J, Evert A, et al. Academy of Nutrition and Dietetics nutrition practice guideline for type 1 and type 2 diabetes in adults: systematic review of evidence for medical nutrition therapy effectiveness and recommendations for integration into the nutrition care process. J Acad Nutr Diet. 2017;117(10): Collins K. New cancer prevention recommendations explained. American Institute for Cancer Research website. Published May 29, Tian Hu, Lu Yao, Reynolds K, Whelton, P, et al. The Effects of a Low-Carbohdyrate Diet vs. a Low-Fat Diet on Novel Cardiovascular Risk Factors: A Randomized Controlled Trial. Published September 7, 2015; Nutrients 5. Aglaée Jacob, MS, RD, CDE. Low-Carb Diets Research Shows They May Be More Beneficial Than Other Dietary Patterns. Today s Dietitian. August 2013 Issue. Vol. 15 No. 8 P Hope Warshaw, MMSc, RD, CDE, BC-ADM, FAADE, and Toby Smithson, MS, RDN, LD, CDE, CCP. Very Low-Carbohydrate Diets. Today's Dietitian. November 2018 Issue. Vol. 20, No. 11, P. 28

39 REFERENCES 6. Pasquale Mansueto, Aurelio Seidita, aaberto D alcamo, and Antonio Carroccio. Nutrition in clinical practice Vol. 30No. 5 Oct Role of FODMAPs in patients with IBS 7. Saslow LR, Daubenmier JJ, Moskowitz JT, et al. Twelve-month outcomes of a randomized trial of a moderate-carbohydrate versus very low-carbohydrate diet in overweight adults with type 2 diabetes mellitus or prediabetes. Nutr Diabetes. 2017;7: Tay J, Thompson CH, Luscombe-Marsh ND, et al. Effects of an energy-restricted low-carbohydrate, high unsaturated fat/low saturated fat diet versus a high-carbohydrate, low-fat diet in type 2 diabetes: a 2-year randomized clinical trial. Diabetes Obes Metab. 2018;20(4):

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