MARATHON Liquid Skin Protectant Supreme protection from friction and moisture that lasts and lasts
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1 MARATHON Liquid Skin Protectant Supreme protection from friction and moisture that lasts and lasts
2 What is MARATHON? MARATHON Liquid Skin Protectant is a non-cytotoxic, cyanoacrylate-based monomer that forms a remarkably strong protective layer over skin. As the cyanoacrylate polymerizes, it bonds to the skin surface. 1 It resists external moisture, yet it allows the skin to breathe. Marathon forms a remarkably STRONG film that: Minimizes friction which reduces the risk of developing skin tears Protects skin from prolonged exposure to moisture, which weakens and damages the skin surface and makes it more susceptible to breakdown 2 Protects skin from the onslaught of corrosive body fluids such as urine, faeces, digestive juices and wound drainage When should MARATHON be used? MARATHON Liquid Skin Protectant is designed to protect skin that is intact or damaged from the effects caused by friction or moisture, such as the following situation and areas. Under Medical Devices Ostomy care, including G-Tubes and tracheostomy Negative pressure wound treatment Tapes and adhesive dressings O 2 tubing Fragile and Compromised Skin tears Perineal and perianal area Periwound area Skin folds (Intertrigo) Heels Skin tear, wrist Ostomy site Buttocks region Closed skin
3 When should MARATHON not be used? Do not apply directly to deep, open or bleeding wounds Do not apply to chronic wounds (persistent or unhealing) Do not apply to second or third degree burns Do not apply to infected areas How does MARATHON work? MARATHON Liquid Skin Protectant consists of individual molecules (cyanoacrylate-based monomers) that polymerize when they come in contact with moisture on the skin surface. This reaction continues until 100% of the monomer molecules have joined either to each other (cohesion) or to molecules of substances present in skin (adhesion). MARATHON Monomer Molecule MARATHON Polymer Chain side chains R = C4H9 (butyl), C8H17 (octyl) ( The bond between the skin and MARATHON The bond between the two monomers ) The double bond between the two carbon atoms breaks when the monomer polymerizes, allowing it to join another monomer molecule. 3 This process is repeated a million-fold, resulting in the formation of a polymer film that protects the skin. 3 This type of bonding ensures that the product remains in place until the epidermal cells naturally slough away 3, maintaining skin integrity. Because no solvents are used, there is no evaporation and 100% of the product remains on the skin. Cyanoacrylate-based barrier Skin A >20 μm layer of cyanoacrylate-based barrier can be clearly seen at x500 magnification. There are NO visible gaps between the skin and Marathon, since it bonded directly to the skin. 3 Solvent-based barrier Skin The approximate <5 μm layer of a solvent-based barrier at x1500 magnification is seen in this image. The gap between the skin and the solvent-based barrier is visible. 3 Gap
4 How does MARATHON work? (continued) An independent test involving 12 people over age 60 compared how bare skin, skin with an application of MARATHON Liquid Skin Protectant, and skin with an application of 3M Cavilon was protected from the effects of abrasion (friction). 4, 5 Transepidermal Water Loss (TEWL) was measured at the application sites as a gauge of skin injury. High TEWL post abrasion was used as a measure of the extent of skin damage. 6 Results: Areas where MARATHON was applied showed better protection of skin from TEWL when compared to Cavilon or no treatment at all. Abrasion Damage to Skin Test No Treatment Barrier Marathon Liquid Skin Protectant 3M Cavilon No Sting Barrier Mean TEWL gm/hr/sq meter Immediately after skin barrier application Immediately post abrasion Independent lab testing data on file. 4 Comparison Cavilon vs MARATHON Cavilon vs No treatment MARATHON vs No treatment P value <0.05 >0.05 <0.001
5 An independent test involving 12 people over age 60 compared how bare skin, skin with an application of MARATHON, and skin with an application of Cavilon resisted exposure to a corrosive fluid (synthetic urine). Results: Areas where MARATHON was applied showed better resistance after each of the five urine and washoff cycles compared to the areas where Cavilon or no product at all were applied. Percentage of retained dye after all five urine and wash-off cycles: (mean percentage) 7 MARATHON 94% Cavilon 66% Skin with no treatment 18% Corrosive Fluids and Wash-off Resistance Test No Treatment Barrier Marathon Liquid Skin Protectant 3M Cavilon No Sting Barrier 110 Percent Dye Remaining (mean percentage) Immediately after skin barrier application After cycle 1 After cycle 2 After cycle 3 After cycle 4 After cycle 5 Independent lab testing data on file. 7 Comparison Cavilon vs MARATHON Cavilon vs No treatment MARATHON vs No treatment P value >0.05 <0.001 <0.001
6 Protection from the effects of moisture and friction Day 1 Day 8 Day 1 Day 10 Managing Skin Tears The management of skin tears in the elderly is an area of concern for healthcare personnel. Skin tear incidence rate in the elderly ranges from 0.9 to 2.5% per person/year. One study reports an acute care incidence range of 14-24%. Skin tears usually result from shear, friction or blunt trauma related insult to the skin. Marathon is a viable option for protection against the effects from friction. 1. Ratliff C, Fletcher K. Skin tears: A review of the evidence to support prevention and treatment. Ostomy/Wound Management 2007; 53(3): McTigue T, D Andrea S, Doyle-Munoz J, Forrester DA. Efficacy of a Skin Tear Education Program: Improving the Knowledge of Nurses Practicing in Acute Care Settings. Journal of Wound, Ostomy and Continence Nursing.2009; 36(5): Managing Peristomal Skin Irritation Under Ostomy Skin Barrier Wafers Peristomal irritation in ostomy patients is a common occurrence and it has been reported that 10 to 70% of ostomy patients experience some type of peristomal skin problems. Leakage of urine, undigested food matter and feces are the major cause of peristomal irritant dermatitis. Prompt management of affected peristomal skin leads to improvement in ostomy barrier wafer efficiency and patient comfort, both of which significantly upgrade the quality of life. 1. Rolstad B, Erwin-Toth P. Peristomal skin complications: Prevention and Management. Ostomy Wound Management. 2004;50(9): Ratliff CR, Scarano KA, Donovan AM,Colwell JC. Descriptive study of peristomal complications. J Wound Ostomy Continence Nursing. 2005;32(1): Herlufsen P, Olsen AG, Carlsen B, et al. Ostomy skin study: a study of peristomal skin disorders in patients with permanent stomas. Br J Nurs. 2006;15(16); Colwell J, Goldberg M, Carmel J. The state of the standard diversion. J Wound Ostomy Continence Nurse. 2001;28: Ratliff CR, Donavan AM. Frequency of peristomal complications. Ostomy Wound Manage. 2001;47: (PubMed) Managing Skin Protection against bodily fluids in the perineal area Marathon acts an exceptional barrier against corrosive bodily fluids when used as a skin protectant (independent lab test results on file) for patients with fragile or damaged skin. Day 1 1. Mary Webb, BSN, MA, RN, CIC San Mateo Medical Center Long Term Care Services, San Mateo, CA Day 16
7 that lasts and lasts and lasts Managing Skin Protection against bodily fluids in the perineal area The corrosive nature of bodily fluids requires a greater amount of protection than what conventional skin preps can provide. Marathon acts an exceptional barrier against corrosive bodily fluids when used as a skin protectant (independent lab test results on file) for patients with fragile or damaged skin. 1. Mary Webb, BSN, MA, RN, CIC San Mateo Medical Center Long Term Care Services, San Mateo, CA Preventing Superficial Tissue Injury Mechanical forces such as friction and moisture applied to the buttocks, coccyx, heels and elbows are especially prone to superficial tissue injury that present as dermal erosions. Marathon has proven to provide extra-protection against abrasive forces and can be used on the areas above to prevent skin injury related to friction. 1. Berlowitz D, Brienza D. Are all pressure ulcers the result of deep tissue injury? A review of the literature. Ostomy/Wound Management 2007; 53(10): No visible difference between two heels.
8 How to apply MARATHON 1. Clean and dry the skin, making sure that no moisturizer or ointment is left on the skin. 2. Hold the applicator upright with the sponge tip at the top. Crush the sealed inner tube by firmly squeezing the middle of the tube. Note: If additional pressure is needed, include your other hand. Do not try to bend or snap the tube in half. 3. Turn the applicator upside down and gently squeeze it to allow the liquid to soak through the sponge tip. 4. Once the sponge is wet, slowly and gently spread a thin, even coat of Marathon that extends about 2.5 cm beyond the affected area. Informative Video Visit to watch a video showing the proper use of Marathon s applicator along with other valuable information. How to Order Contact your Medline representative or call MEDLINE. For direct sales to patients, visit shop4remedy.com. ORDERING INFORMATION Item Number Description Packaging MSC Marathon Liquid Skin Protectant 10 ea/bx MSC Marathon Liquid Skin Protectant 5 ea/bx References 1 Bond P. Scanning Electron Microscope Examination and Assessment of SUPERSKIN (Liquishield S) University of Plymouth, UK. Data held on file at MedLogic Global Limited. 2 The Merck Manuals Online Medical Library. Pressure Sores. Available at: qt= moisture%20skin%20damage&alt=sh#sec18-ch205-ch205a Coover HW and McIntire JM. Cyanoacrylate Adhesives. In:Skeist, I, ed. Handbook of Adhesives. 2nd ed. New York: Van Nostrand R inhold Co.;1977: Abrasion Test. Data on file. 5 Pinnagoda J, Tupker RA, Anger T, Serup J. Guidelines for transepidermal water loss (TEWL) measurement. Contact Dermatitis. 1990;22: Nangia A, Patil S, Berner B, Boman A et al. In vitro measurement of transepidermal water loss: a rapid alternative to tritiated water permeation for assessing skin barrier functions. International Journal of Pharmaceutics. 1998;170(1): Study to Compare the Wash-off Resistance of Two Barrier Films Exposed to Synthetic Urine. Data on file. Medline Industries, Inc. One Medline Place Mundelein, IL Medline United States MEDLINE ( ) Medline Canada canada@medline.com Medline México mexico@medline.com 2013 Medline Industries, Inc. All rights reserved. Some products may not be available for sale in Mexico or Canada. We reserve the right to correct any errors that may occur within this brochure. 3M and Cavilon are registered trademarks of 3M Company Corporation. Medline and MARATHON are registered trademarks of Medline Industries, Inc. MKT / LIT183R
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