DFG-SPP. Sphingolipids - Signals and Disease. Meeting 2009

Transcription

1 DFG-SPP Sphingolipids - Signals and Disease Meeting 2009 University Hospital Essen Hörsaal - Operatives Zentrum II

2 Friday, September 4, am Welcome Reception I) MEMBRANES, ENZYMES AND INHIBITORS am Konrad Sandhoff, University of Bonn Does ceramide play a role in late endosomes? am Felix Wieland, University of Heidelberg Specificity of protein lipid interaction within the hydrophobic core of membranes am Stefan Schütze, University of Kiel Molecular mechanism of A-Smase activation in TNF receptosomes am Annette Draeger, University of Bern Annexin 1 as a biomarker for ceramide platform dynamics pm Pin Lan Li, Virginia Commonwealth University Lipid Rafts-Lyosome Signaling Platforms in Endothelial Cells pm Emilio Clementi, Christiana Perrotta, DIBIT-H San Raffaele Institute Milano Acid sphingomyelinase, syntaxin 4 and nitric oxide: unsuspected links in CD95 signalling pm Christoph Arenz, Humboldt University Berlin Small molecule inhibitors of acid Sphingomyelinase pm Lunch

3 II) IMMUNE FUNCTIONS AND INFLAMMATORY DISEASES pm Irina Petrarche, Indiana University The effect of sphingolipids dysregulation on lung parenchyma; Implications for human COPD pm Erich Gulbins, University of Duisburg-Essen The role of sphingolipids in cystic fibrosis pm Stefan Uhlig, Wolfgang Kübler, University Hospital of Aachen, Universitiy Hospital of Berlin The regulation of pulmonary vascular permeability by acid sphingomyelinase pm Ralf Claus, University of Jena Hyperresponsiveness of mouse deficient in Asm reveals its vital role in early stages of inflammatory response pm Coffee Braek pm Klaus Fassbender, Silke Walter, University of the Saarland/Homburg an der Saar Acid Sphingomyelinase and Experimental Multiple Sclerosis pm Ana Olivera, NIH Sphingosine-1-phosphate is a regulator of both the onset and the resolution of systemic anaphylaxis pm Hermann Eibel, University of Freiburg Sphingosine 1-phospate receptors regulate migration of human B lymphocytes pm Markus Gräler, Medical University of Hannover Distribution of sphingosine 1-phosphate from blood into lymphoid tissues: The role of sphingosine kinases pm Burkhard Kleuser, University of Berlin Modulation of Langerhans cell migration via S1Psignalling pm Dinner Restaurant Hülsmannshof

4 Saturday, September 5, 2009 III) DEVELOPMENT, DIFFERENTIATION AND DEATH am Edward Schuchman, Mount Sinai School of Medicine Acid Ceramidase and Cell Survival: Specific applications to reproductive medicine and stem cell biology am Paola Bruni, University of Florenz Sphingosine 1-phosphate signalling in skeletal muscle cell differentiation and regeneration am Johannes Kornhuber, University of Nürnberg- Erlangen Acid sphingomyelinase and major depressive disorder am Coffee Braek am Tony Futerman, Weizman Institute of Science A critical role for synthesis of very long acyl chain ceramides in liver homeostasis am Tobias Hartmann, University of the Saarland/ Homburg an der Saar Sphingolipid metabolism regulation by Alzheimer's disease amyloid beta peptides and precursor proteins pm Florian Lang, University of Tübingen Ceramide in suicidal erythrocyte death pm Richard Kolesnick, Memorial Sloan Kettering Cancer Center Vascular dysfunction and acute hypoxia impair double strand break repair in tumor stem cells Lunch

5 IV) CARDIO-RENO-VASCULAR SYSTEM pm Marcus van der Gieth, Charité University Hospital of Berlin The role of sphingolipids for endothelial functions pm Bodo Levkau, University of Duisburg-Essen S1P in macrophage-driven inflammation and atherosclerosis pm Bernhard Rauch, University of Düsseldorf The release of Sphingosine-1-phosphate from human platelets is dependent on thromboxane synthesis pm Andrea Huwiler, Josef Pfeilschifter, University of Bern, University of Frankfurt The TGF- β-induced CTGF expression is under suppressive control of sphingosine kinase-1 in podocytes in vitro and in vivo End of SPP-Annual Conference pm Meeting of all Applicants