Lymphatic Vessels & Lymph lymphatic vessels. 20 The Lymphatic System. They can't all be superstars! The Lymphatic System. Keeps us healthy!

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1 They can't all be superstars! The Lymphatic System Lymphatic System: 1. lymphatic vessels 2. lymph 3. irculation, P, Supports immune & clotting, etc... cardiovascular system! Lymphoid Organs & Tissues: *returns "leaked" fluid 1. spleen to bloodstream *discrete organs/tissues 2. thymus aiding in defense *supports V system 3. tonsils *supports Keeps us healthy! immune system 4. other (Peyer's patches) Functions produces, maintains and distributes lymphocytes (cells that attack invading organisms, abnormal cells, and foreign proteins) - lymphoid organs/tissues helps maintain blood volume and the consistency of interstitial fluid (fluid forced out of arteries and reabsorbed by veins) - lymphatic system HOW O PILLRIES EXHNGE NUTRIENTS/WSTES? hydrostatic blood pressure due to contraction OUT "downstream" pressure ventriclediminishing OUT OUT voice colloid osmotic of left "upstream" IN IN due to proteins in blood (albumins) constant IN voice *most fluid forces out "upstream" is reabsorbed "downstream" *to maintain proper blood volume, whatever is not reabsorbed needs to be returned to bloodstream *lymphatic vessels return about 3L of "leaked" fluid, plasma proteins, and digested fats per day Lymphatic Vessels & Lymph lymphatic vessels > elaborate network of one-way vessels that lead toward heart (R side) > not in bones/teeth, bone marrow, or NS lymphatic capillaries EXTREMELY PERMELE > minivalves open when pressure greater outside than in lymph - fluid inside vessels > similar to blood plasma

2 1 Lymphatic vessels originate in lymph fluid 2 is the fluid found inside lymphatic vessels. tonsils tissue capillaries 3 Functions of the lymphatic system (defense and reabsorption of fluid) supports the actions of the cardiovascular system nervous system respiratory system immune system 4 Fluid enters lymphatic capillaries when the pressure is greater than the pressure the capillary. inside, surrounding inside, outside outside, inside outside, surrounding

3 Lymphoid ells lymphoid cells - lymphocytes main warriors of the immune system T cells (thymus-dependent) responsible for cell-mediated immunity cytotoxic T cells - attack foreign cells, abnormal body cells, and cells infected by viruses regulatory T cells - regulate and coordinate the immune response (helper T cells and suppressor T cells) cells (bone marrow-dependent) responsible for antibody-mediated immunity differentiate into plasma cells, which produce and secrete antibodies that react with or bind to antigens antibodies = immunoglobulins macrophages - phagocytize foreign substances and help activate T cells dendritic cells - capture pathogens and bring them to cells non-presenting presenting (P) body cells macro, dendritic, cells MH II MH I (two I'll help you) (one and done) I'm infected under attack... I die here's invader (attack invader) (attack infected cells) memory cells for later activate TH activate & T 5 cells are responsible for mediated immunity. 6 T cells mature in the spleen tonsils thymus

4 Normal Intestine Lymphoid Tissue iffuse lymphoid collections of loose connective tissue and lymphocytes found in nodules full of macrophages functions house lymphocytes ideal surveillance vantage point tissue - scattered, Follicular lymphoid tissue solid, tightly packed *enlarge when cells dividing into plasma cells found in all lymphoid organs EXEPT thymus lymphocytes loosely packed amaged Intestine due to HIV Infection macrophages Lymphoid Organs - Lymph Nodes Lymphoid Organs - Lymph Nodes principle lymphoid organ (100s embedded in connective tissues throughout body) afferent large superficial groups in inguinal, axillary, and cervical regions efferent 2 functions > "filter" lymph returning to bloodstream > help activate immune response 7 MT: What type of cells are stored in? THINK OUT macrophages immunoglobulins plasma cells lymphocytes IT...WHT IS THE JO OF LYMPH NOE N WHT WOUL HELP HIEVE THIS FUNTION?

5 8 The main difference between diffuse and follicular lymphoid tissue is their location in the body their function the flow of blood through their structure how they are "packaged" (tightly or loosely) Other Lymphoid Organs tonsils - simplest lymphoid organ gather and remove many pathogens entering pharynx in food or inhaled air 4 sets: palatine, lingual, pharyngeal (adenoids), tubal spleen - largest lymphoid organ lymphocyte proliferation, immune surveillance, removes defective blood cells and platelets from blood, stores platelets, stores iron obtained from recycled Rs thymus atrophies as we age (most active in young children) where T cells mature and are stored *tubal not shown 9 MT: hoose the lymphoid organs. tonsils thymus spleen 10 The largest lymphatic organ is the.