Ozone-Therapy. Medical Ozone. Applications and Indications. Ozone Seminar Bad Kreuznach March 26 27, May 23, 2003 OZONOSAN 1

Transcription

1 Ozone-Therapy Applications and Indications of Medical Ozone Ozone Seminar Bad Kreuznach March 26 27, 2004 May 23, 2003 OZONOSAN 1

2 Medical Ozone Medical Ozone is a mixture of pure Oxygen and pure Ozone 0,05 % O 3-5 % O 3 (Vol.) 99,95 % O 2-95 % O 2 1 µg /ml µg/ml O 3 May 23, 2003 OZONOSAN 2

3 Processing of the Medical Ozonegenerator: OZONOSAN Ozoneproduction Photometric ozone measurement O 2 O 3 O 3 O 2 Catalyst: O 3 O 2 O 3 Ozone supplyer O 3 O 2 Catalyst: O 3 O 2 O 3 Ozone suction pump O 3 Ozone applications May 23, 2003 O 2 OZONOSAN 3

4 OZONOSAN photonik equiped with UV-Photometer for continous measurement of ozone concentrations Concentration range: 1- ca 80 µg/ ml Suction pump highly effective catalyzer system Option: unit for ozononized water May 23, 2003 OZONOSAN 4

5 OZONOSAN alpha plus equiped with UV-Photometer for continous measurement of Ozone concentrations Concentration range: 1- ca130 µg/ ml Suction pump highly effective catalyzer system Integrated unit for ozonized water May 23, 2003 OZONOSAN 5

6 Indications of Ozonetherapy External Ulcers and Skin Lesions Arterial Circulatory Disorders Immunodeficiency and Immunodysbalance - Additive Therapy in Carcinoma Patients - Virus Caused Diseases Rheumatic Diseases Inflammatory Conditions Dentistry May 23, 2003 OZONOSAN 6

7 Systemic Forms of Application Major Autohemotherapy MAH extracorporeal blood treatment with O 3 and reinfusion of activated blood as Rectal Insufflation of O 3 -O 2 mixture Minor Autohemotherapy as intramuscular injection of activated blood May 23, 2003 OZONOSAN 7

8 Major Autohemotherapy Major Autohaemotherapy as extracorporeal blood treatment avoiding intravascular gas application forms. Indications: - Arterial circulatory disorders - Immunomodulation - Rheumatoid arthritis May 23, 2003 OZONOSAN 8

9 Rectal insufflation for systemic und topical efficacy Indications: Proctitis Colitis and the Indications for Major Autohemotherapy 1. Dosing ball (150 ml) 2. Ozone reserve container 3. Lock valve 4. Return valves 5. Connection tube (luer) 6. Catheter May 23, 2003 OZONOSAN 9

10 Ulcerous Proctocolitis Florid Stage of Proctocolitis: Pat. female, 45 yrs. Destruction of epithelium, cryptal abscesses, massive leucocytic infiltration, partially under inclusion of the tunica propria (350x) Control biopsy after 4 weeks: Manifest reversal of inflammation. Intact epithelium after rectal ozone insufflation with µg/ml and 300 to 500 ml in volume. (Knoch et al. Aktuelle Koloproktologie ) May 23, 2003 OZONOSAN 10

11 Ulcerous Proctocolitis Florid Stage of Colitis Pat. male 62 yrs. Cryptitis with cryptal abscesses, chronic inflammation, destruction of the epithelium and massive infiltration of leucocytes (350x). Control biobsy after 4 weeks: regular epithelium, regular glandular tubes. Moderate leucocyte infiltration, manifest reversal of inflammatory changes after 4 weeks of rectal ozone insufflation with 8,5-27 µg/ml and 300 ml dayly, 3x per week. (Knoch et al. Aktuelle Koloproktologie ) May 23, 2003 OZONOSAN 11

12 Minor Auto Hemo Therapy Extracorporeal blood treatment: 10 ml ozone with a concentration of µg/ml + 2-3ml of patient s own blood and intramuscular injection Indications - Allergies, - Acne, furunculosis, - Supportive cancer therapy by non specific activation of the immune system, general stimulation May 23, 2003 OZONOSAN 12

13 Topical Forms of Application Transcutaneous Ozone Gas Application in gas-tight and ozone-resistent plastic covers Ozonized Water in the form of spray or compresses Rectal O 3 -O 2 Insufflation Intraarticular Injections Ozonized olive oil May 23, 2003 OZONOSAN 13

14 Local Ozone-Treatment in the form of the low pressure system acc. to Werkmeister Indications Decubitus ulcer Badly healing wounds Diabetic gangrene Burns May 23, 2003 OZONOSAN 14

15 Ozone Treatment in Surgery 1915 A. Wolff Werkmeister E. Payr 1937 P. Aubourg 1977 O. Rokitansky 1981 H. Werkmeister, 1987 H.G. Knoch, 2002 Calderon, N.A. Kauffmann, T May 23, 2003 OZONOSAN 15

16 The Use of Ozonized Water in form of spray or compresses in the Held, P May 23, 2003 OZONOSAN 16

17 Subcutanous, intracutanous and intramuscular injections 1979 Herget Gießen 1999 Balkanyi Zürich Indications - Myotraumatic syndrome - Myogelosis eg in combination with tonanalgetic treatments May 23, 2003 OZONOSAN 17

18 Intraarticular Injections in Orthopedics 1981 Z. Fahmy, Bad Kreuznach, Germany 1989 E. Riva- Sanseverino, Bologna, Italy Indications: - Knee arthrosis, - Gonarthrosis - and rheumatoid arthritis as supportive therapy May 23, 2003 OZONOSAN 18

19 Mechanism of Action in Topical Applications 1. Microbicidal Effects, ie bactericidal, fungicidal, virustatic 2. Wound cleansing effect 3. Wound healing effect 4. Topical immunoactivation May 23, 2003 OZONOSAN 19

20 Mechanisms of Action in MAH 1. Activation of Immunocompetent Cells 2. Activation of Red Blood Cell Metabolism 3. Activation and Induction of Biological Antioxydants and Radical Scavengers May 23, 2003 OZONOSAN 20

21 Concentration 100 µg/ml o 10 Application topical application topical +system. application, limit for system. treatment systemic treatment Indication superinfected wounds colitis badly healing wounds proctitis ciculatory disorders, immunodysbalance revitalization, improvement of wound healing Efficacy germicidal wound - cleansing germicidal, activation of cell metabolism immunomodulation, activation of RBCmetabolism,in- crease of antioxidants May 23, 2003 OZONOSAN 21

22 Contra Indications and Applications Contra Indications 1. Glucose-6 Phosphat- Dehydrogenase- Deficiency (Favism) 2. Hyperthyroidism Contra Applications 1. Intravenous Gas Injections 2. Intraarteriel Gas Injections 3. Hyperbaric Reinfusion May 23, 2003 OZONOSAN 22