Apitherapy. Edition 7.0 Date of issue:

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1 GB Apitherapy Inhalation of aerosol from the hive Inhalation of aerosol from the hive with forced draft Devices for aerosol inhalation therapy Inhalation mixtures Concentrates for mixing with honey Edition 7.0 Date of issue:

2 Čebelarstvo Kolarič INHALATION AEROSOL APITHERAPY 1 Inhalation of aerosol from the beehive, can effectively treat many respiratory illnesses such as sore throat, chronic obstructive pulmonary disease, chronic bronchitis, emphysema, tracheobronchitis, bronchiolitis, and other (source, Peter Kaps, 2012). Beside the inhalation of aerosol from the hive, people can also inhale other bee products such as honey, propolis and pollen. Bee products must be prepared properly to be suitable for use with a nebulizer. A nebulizer is a device that breaks the liquid substance into small particles (aerosol), which is then transported to the respiratory system using a mask or a mouthpiece. Inhalation of aerosol from the hive. API AEROSOL I. Bees form aerosol with their movement in the hive. By using API AERSOL I set, a person can inhale aersol directly from the hive. An adapter, that is attached to the hive, has a special one-sided shut-off valve, which allows the movement of the aerosol from the beehive to the user. A ribbed connecting tube has a sufficiently large diameter to allow the flow of aerosol from the hive (6-10 liters per second). The tube can be connected with a mouthpiece or a mask. The mask has two one-sided shut-off valves built in, that allow suction from the tube and discharge of exhaled air to the surroundings. Due to hygiene reasons, each user should have its own tube, mask or mouthpiece. symbolic picture Set API AEROSOL I contains: Mask for apitherapy with shut-off valve (Code: 1041) Flexible pipe 120 cm (Code: 1033) Hive adapter (Code: 1042) Mouthpiece (Code: 1022) Code: Set API AEROSOL I Inhalation of aerosol from the hive with forced draft API AEROSOL II Intalation of aerosol from the hive with forced draft, enables a greater flow of aerosol from the hive, by using a fan (API AEROSOL I), which can be powered directly via 230V/12V adapter or 12V batteries (API SUPPLY).

3 API AEROSOL II fan, may be set at 5 speeds in order to regulate the speed of the fan and the flow the aerosol from the hive to the user. Up to 10 fans of API AEROSOL II can be linked together, which enables inhalation of larger groups of users at a time. Set API AEROSOL II *Possible to use with or without a special filter (special filter comes with the set) Code: (1) (1) (2) (3) (4) The figure shows the power supply of one or more fan units Api aerosol-ii (1) through the battery unit API SUPPLY (2) or 220V/12V adapter (3) or 12V battery (4). Components for inhalation from the hive: Mask for apitherapy with shut-off valve Code: 1041 symbolic picture Set API AEROSOL II contains: Fan unit Apiaerosol II (Code: 01054) Adapter 230V/12V (Code: 01055) Professional mask for apitherapy with oneway air valve L (Code: 01067) Professional tube with a smooth inner surface (Code: 01068) Mouthpiece (Code:1022) Code: API-SUPPLY (battery unit) API supply is the battery unit that provides power to 10 fan units (Api-aerosol II) where there is no electricity grid. API supply contains 12V battery. It can be connected with 12V battery or adapter 220V/12V. The device consists of three-tier switcher and voltage displayer. The device can be grounded. Children mask for apitherapy with shut-off valve Code: Flexible pipe 120 cm Code:

4 Professional mask for apitherapy with oneway air valve L Code: Fan unit Api-aerosol II Code: Connecting cable to connect multiple API AEROSOL II units Code: Professional mask for apitherapy with oneway air valve M Code: Professional tube with a smooth inner surface Code: Hive adapter Code: 1042 Mouthpiece Code: V/12V adapter Code: Battery unit Api-supply Code: Api aerosol filter Code: V power cord with fuse (for connection to the battery) Code: pieces of silicone membranes for nonreturn valve Code: ml bottle with a nozzle (for cleaning with a 70% alcohol) Code: Fan Code: Switching regulator Code: 01063

5 are then broken down by the ampoule into an aerosol. The aerosol travels straight from the hive into the upper (nasal cavity, oral cavity, pharynx, and larynx ) and lower (trachea, bronchi, bronchial tubes, alveoli - air sacs) airways. Piston nebulizer ME100 (includes: mask for adults, children s mask, ampule for medicine, tube length of 1.1 m, mouthpiece, five filters). Čebelarstvo Kolarič Inhalation of aerosol from the hive with forced draft Set for inhalation from the hive with a forced draft, enables a greater flow of the aerosol from the hive. It allows the inhalation of various substances, which can optionally be added to the inhaler (nebulizer) dispenser. Inhalation from the hive with a forced draft is enabled by using the piston nebulizer (Me100). The nebulizer s aggregate forcibly pumps aerosol from the hive into the dispenser, which is connected to the mouthpiece or mask. The dispenser is designed to add the appropriate active substances (honey, propolis, pollen, physiological saline, medications, etc.), which The components for inhalation from the hive with forced draft: Hive adapter and a suction tube with a connector for the piston nebulizer ME100, Code: 1043 Code:

6 Devices for aerosol (Api)therapy Devices for aerosol (Api)therapy work by breaking the liquid into microscopic drops (0.5 to 6 μm). A small amount of drops are put in the nebulizer which then breaks the liquid into a fine mist which is called aerosol. The mass of the aerosol mist/drops is so low that they can easily enter the respiratory system. The drops are in liquid and gaseous form, which means they can carry a variety of dissolved substances such as: salt, medicines or substances from bee products (honey, propolis or pollen). The dissolved substances in the form of aerosol then travel to the upper and lower respiratory tract where they have a therapeutic effect. Me120 (ultrasonic nebulizer) Technical characteristics: ultrasonic method of forming an aerosol, useful for inhalation of physiological saline, medicines or products made from honey, propolis and pollen, maximum noise level: 35 db/m, voltage: 230 V/50Hz, weight: 0,42 kg. Me100 (piston nebulizer) Technical characteristics: possible use of inhalation of aerosol from the hive by purchasing a suction tube with a nebulizer connector, the use for inhalation of physiological saline, medicines or products made from honey, propolis or pollen, pump: piston compressor, operating air pressure: 1:00 to 1:30 Bar, max. noise level: 57 db/m, voltage: 230 V/50Hz, weight: 1,27 kg, dispersion velocity : 0.5 milliliters/min, average particle size: 4.97 μm. Set contains: unit with connection cable, mask for adults, children s mask, ampoules for medicine, tube length of 1.1 m, mouthpiece, five filters, instructions for use. Code: 1001 Me100 5

7 Set contains: unit with adapter and connection cable mask for adults, children s mask, 10 ampouls for medicine, folding tube and joint for the mask, mouthpiece, nosuspiece, five filters, instructions for use. Me120 Me120Plus (ultrasound nebulizer and humidifier) Technical characteristics: ultrasound method of forming an aerosol useful for the inhalation of physiological saline, medicines or products made of honey, propolis, royal jelly, useful for moisturizing the area and aromatherapy with honey substances, maximum noise level: less than 35 db/m particle size: 0.5 to 5 μm for 85% of all particles, voltage: 230 V/50Hz, power consumption: 55 VA, weight: 1.95 kg Max. volume of cups for medicines: 50 ml, max speed of producing aerosols: 3-5 ml/min time setting: 0-60 min, ability to adjust the speed, function of air humidification. Set for air humidification adapter for the bottle, bottle, hygrometer. Me120Plus Code: 1009 Set contains: unit with connection cable, mask for adults, children mask, mouthpiece, 5 cups for medicine, 3x flexible pipe 2x junction. Code:

8 All Api-Inhal mixtures are made from natural extracts and ingredients only. Api-Inhal mixtures are used for inhalation aerosol therapy with one of Medikoel nebulizers. Api-Inhal Inhalation mixture against cold and flu It contains honey, propolis, salt, concentrated extract of echinacea, pine buds, nettle, mallow, elder, thyme and raspberry. Inhalation mixture against cold and flu can help eliminate the microbes and moisturizes/cleanses the mucous membranes of the respiratory tract. Api-Inhal Inhalation mixture to help with allergy or seasonal allergic rhinitis It contains salt, propolis, a concentrated extract of echinacea, pine buds, nettle, honey and pollen. Inhalation mixture to help with allergy or seasonal allergic rhinitis can be used to help open up the airways and for moisturizing and cleaning the mucous membranes of the respiratory tract. Api-Inhal Anti-inflammatory inhalation mixture for the upper airways It contains honey, salt, concentrated extract of echinacea, pine buds, peppermint, thyme, yarrow, linden blossoms and nettle. Antiinflammatory inhalation mixture for the upper airways can be used to help open up the airways, for moisturizing and cleaning the mucous membranes of the upper airways. Code: Code: Code:

9 Api-Inhal Inhalation mixture against bronchitis It contains honey, propolis, salt, concentrated extract of echinacea, pulmonaria, icelandic moss, plantain, mallow and nettle leaves. Inhalation mixture against bronchitis can work against microbes, and moisturizes/cleanses mucous membranes of the respiratory tract. It can help by relieving the symptoms of bronchitis. Api-Inhal Soothing blend for inhalation It contains honey, salt, extract of valerian, lemon balm, lavender and nettle. Inhalable emollient. Use the mixture to help alleviate the problems of the nervous system. Soothing blend for inhalation can have a soothing effect and can helps to improve the quality of sleep. Api-Inhal Inhalation mixture of beetroot and propolis It contains honey, propolis, salt, concentrated beetroot juice, extract of pine buds and nettle. Inhalation mixture of beetroot and propolis is used when dealing with anemia or anemia during pregnancy, after childbirth, during breastfeeding, in long-term and chronic diseases, increased sports activities and during a wide variety of diseases. Code: Code: Code:

10 Api-Inhal Inhalation mixture of Aloe arborescens It contains honey, propolis, salt and extract of Aloe arborescens. The plant Aloe arborescens has a broad spectrum of positive activity on a wide variety of problems, diseases and disorders. Inhalation mixture of Aloe arborescens is used for the purpose of maintaining health (to help stimulate the immune system and to help with asthma, inflammation of the eyes, skin, etc.). Code: CONCENTRATE FOR MIXING WITH HONEY Natural honey is an excellent preservative. You can mix a lot of different substances into honey. These substances must not contain a lot of water otherwise the honey may spoil. It is necessary to concentrate and separate the fluids from the solution. For this purpose we use a special vacuum technological process. This process is called evaporation and consists of separation of different solvents from the solution. Low temperature (up to 40 C) is key for such a process of concentration, because higher temperatures destroys active substances in ingredients. All Medikoel concentrates are made with the evaporation process to ensure that the concentrate will not separate from the honey, once they are mixed, thus making the mixture homogeneous. Code: Concentrated extract from echinacea (Echinacea purpurea L.) contains 125 g of concentrated extract from echinacea, sufficient for 5 kg of honey, easy to use, added vitamin C. Impact on health: The active ingredients of Echinacea (Echinacea purpurea L.) are the only substances which the European Medicines Agency recognizes for its immune stimulating effects. Echinacea is proven to strenghten the resistance of our immune system. The advantage of Echinacea with honey is that their combination has a beneficial effect on the elimination of symptoms (the effect of honey) and treatment (effect of the Echinacea) of common cold or influenza. It is well known that honey, because of its beneficial properties helps to relieve coughs, sooths sore throats and has antioxidant and antibacterial properties. On the other hand, Echinacea enhances the body s resistance, which helps to accelerate recovery. Echinacea with honey contains added vitamin C. It is also suitable for children because it does not contain alcohol, preservatives and has a pleasant taste. 9

11 Instructions for making honey with echinacea: Pour the content of the bottle (125 g) into 5 kg of honey. Mix until you get homogeneous mixture. Fill the mixture in 250 g glasses, equip them with a label and place them in the carton packaging. Instructions for making honey with beetroot: Pour the content of the bottle (125 g) into 1 kg of honey. Mix until you get homogeneous mixture. Fill the mixture in 250 g glasses, equip them with a label and place them in the carton packaging. Concentrated extract from pine buds is designed for mixing in products, where it is not desirable that their physical properties change due to water content. It is therefore particularly suitable as an addition to honey. Concentrate blended into honey is used to help to calm coughing and to help with colds. Concentrated juice from the Beetroot (Beta Vulgaris L.) contains 125 g of concentrate from red beet juice sufficient for 1 kg of honey, easy to use. Instructions for making honey with pine buds: Pour the content of the bottle (500 g) into 1,5 kg of honey. Mix until you get homogeneous mixture. Fill the mixture in 250 g glasses, equip them with a label and place them in the carton packaging. 16 times concentrated juice of red beet is created by using low temperature distillation. With that process we achieve stability of freshly squeezed juice from red beet. Cold concentrated juice of red beet is designed for mixing into the products, where it is not desirable that their physical properties change due to water content. It is therefore particularly suitable as an addition to honey. Code: Concentrated extract from pine buds (Picea abies L.) contains 500 g of concentrate from pine buds, sufficient for 1,5 kg of honey, easy to use. Code:

12 Medikoel d.o.o. Jalnova cesta 2, 4240 Radovljica t.: (0) , f.: (0) Matjaž Pogačnik, gsm.: (0) info@medikoel.com, Company Medikoel d.o.o. is a registered medical device manufacturer at the Public Agency of the Republic of Slovenia for Medicinal Products and Medical Devices. Number of entry / All products ME100, Me120, Me120 PLUS medical devices are registered in the register of medical devices managed by the Public Agency of the Republic of Slovenia for Drugs and Medical Devices and comply with the European Directive 93/42/EEC.

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