Catecholamines and neurotransmitter. Comprehensive tools for routine and research
|
|
- Luke Booth
- 6 years ago
- Views:
Transcription
1 Catecholamines and neurotransmitter diagnostics Comprehensive tools for routine and research
2 Neurotransmitters in human and animals Catecholamines and neurotransmitters play essential roles in both humans and animals. They are involved in a wide range of physiological and patho-physiological conditions. IBL International offers a very exciting line of immunoassays for the detection of catecholamines and neurotransmitters. The benefits of IBL catecholamine and neurotransmitter immunoassays are: IBL is the first company to offer commercial immunoassays internationally for measurement of catecholamines and neurotransmitters IBL has more than 25 years experience in production with the highest quality standards, and a world-wide distribution network for these immunoassays Assay results correlate very well with HPLC Assays are applicable to both human and veterinary medicine Adrenalin, Noradrenalin and Dopamine ELISA Reliable plasma measurement Catecholamine ELISA for research IBL offers enzyme immunoassays and radioimmunoassays for measurement of catecholamines and their metabolites metanephrines in urine and plasma samples. They are applicable in routine and research laboratories. The highly sensitive assays provide results comparable to HPLC. Because of the extraction step at the beginning of the catecholamine assays, researchers are able to use materials from many types of animal species, as well as tissue homogenates and cell cultures supernatants. The chemical structure of the catecholamines is identical in all animals. Several papers published in peerreviewed journals using IBL catecholamine test kits prove the applicability of these kits in various areas of research.
3 Make use of the many that IBL assays offer! of individual and combi ELISA kits Kits can be used for measurement of both plasma and urine with the same standard curve In contrast to HPLC, there are currently no known drugs that interfere with the test, thus avoiding potential false interpretations of several clinical states Validated for open automated ELISA systems, resulting in a high possible throughput for samples Metanephrine and Normetanephrine ELISA Plasma metanephrine immunoassays validated in multi-center study The IBL metanephrine immunoassays (both RIA and ELISA) have been validated in a multi-center study on their diagnostic value for the determination of free plasma metanephrines in the work-up for pheochromocytoma with convincing results (cf. Lenz et al., Ann N Y Acad Sci). After successful surgery, metanephrine levels will drop down into the normal range, as shown in the figure below. 350 Free metanephrine 2000 Free normetanephrine (pg/ml) upper limit normal range (pg/ml) upper limit normal range 0 0 before surgery after surgery before surgery after surgery Example of a pheochromocytoma patient with metanephrine levels before and after surgery.
4 Measurement of urinary individual metanephrines Recent publications show urinary normetanephrine and metanephrine excretion as a sensitive test for diagnosis of pheochromocytoma. However, such high clinical sensitivity can be achieved only through individual measurements for each of these substances, and not simply through the total amount. IBL metanephrine assays fulfill all these requirements. for free plasma metanephrine immunoassays Best test for excluding or confirming pheochromocytoma Good agreement with the reference method LC- MS/MS, but no expensive equipment needed Immunoassays can be integrated in any normal laboratory, and are not restricted to highly specialized laboratories Tests have been validated in multi-center studies Serotonin and 5-HIAA ELISA The determination of serotonin in serum and platelets as well as the determination of 5-HIAA from a 24- hour collection of urine samples is currently well-accepted for routine diagnoses of carcinoid tumors. Circulating serotonin is metabolized to 5-hydroxyindole acetic acid (5-HIAA), which is excreted in urine. IBL offers kits for both substances in ELISA format. Serotonin ELISA in research The IBL serotonin ELISA has been successfully used in research studies of various kinds. The assay requires a small sample volume of 20 µl only, and has been used with mice, rat brain tissue, ringdoves, fish serum and tissue, rabbits, cell cultures supernatants and bronchoalveolar lavage fluids. This data has been published in well-known journals. of serotonin ELISA Excellent correlation with HPLC Broad standard range; convenient measurements for pathological samples Highly sensitive in measuring very low serotonin concentrations, such as plateletfree plasma
5 Melatonin and 6-Sulfatoxymelatonin (Melatoninsulfate) Melatonin is an endogen hormone produced by the pineal gland located in the human brain. Daylight results in a considerably lower plasma melatonin level, but at night the pineal gland increases its melatonin secretion. IBL offers ELISA and RIA kits for reliable measurement of melatonin concentrations in serum, plasma and saliva. Melatonin is subsequently metabolized to 6-sulfatoxymelatonin, which is excreted in urine. Recent studies with IBL s 6-sulfatoxymelatonin ELISA have shown that the 6-sulfatoxymelatonin concentration is age and time dependent (cf. Mahlberg et al., Psychoneuroendocrinology, see also the figure below) sulfatoxymelatonin (ng/h) h h h h h Time and age dependent normal values of 6-sulfatoxymelatonin in urine y (n = 26) y (n = 17) y (n = 16) >65 y (n = 16) Melatonin in saliva New studies have shown that melatonin levels in saliva may represent a robust and reliable alternative to serum melatonin measurement, especially for diagnosis of sleep disturbances such as insomnia. IBL offers a direct ELISA without sample pretreatment.
6 Melatonin ELISA for research The IBL melatonin ELISA has been used successfully in a wide range of melatonin research areas, including various plants and diets, such as beer, sunflower sprouts, red wine and olive oil. Melatonin ELISA has also been used successfully to measure melatonin in the pineal glands of deep-sea fish, extrapineal rat tissues and mouse tissue. The results of these studies have been published in prestigious journals. of melatonin and 6-sulfatoxymelatonin RIA and ELISA calibrated to LC-MS/MS Broad standard range, applicable to therapeutic drug monitoring Age and time dependent normal values validated for 6-sulfatoxymelatonin Through extraction, melatonin ELISA is applicable to human, animal and plant specimens Histamine Histamine has been clearly implicated as a primary mediator of acute phase allergic reactions. Following stimulation of mast cells and basophiles, histamine is released explosively into the surrounding tissues and body fluids. sensitised mast cell with IgE IgE receptor antigen (= allergen) IBL offers a highly sensitive histamine ELISA, which can be used both in routine and in research laboratories. granula with mediators bridging via antigens leads to release of mediators Allergen-induced histamine release.
7 Determination of histamine levels in research The histamine ELISA has been used in cell cultures, mice and rats, as well as bronchoalveolar lavage in horses. The results of studies using IBL test kits have been published internationally in well-known journals. of IBL histamine ELISA Total assay time of about 4 hours only Wide standard range permits handling of highly elevated histamine concentrations without additional sample dilution Assay applicable to a variety of different animal specimens overview catecholamines / neurotransmitter ELISA RIA 5-Hydroxy indole acetic acid (5-HIAA) x Adrenalin (Epinephrine) x x Dopamine x Histamine, Histamine release x Metanephrine x x Melatonin x x Melatoninsulfate (6-Sulfatoxymelatonin) x Noradrenalin (Norepinephrine) x x Normetanephrine x x Serotonin x For detailed information please visit our website at
8 IBL International GmbH Flughafenstrasse 52 a D Hamburg Germany Phone: +49 (0) Fax: +49 (0) IBL@IBL-International.com w w w. I B L - I n t e r n a t i o n a l. c o m Catecholamines 10/09
IMMUNOASSAYS AND SERVICES
2017 biogenic amines & neuroscience endocrinology food SafeTY IMMUNOASSAYS AND SERVICES 2 TABLE OF CONTENT BIOGENIC AMINES & NEUROSCIENCE 4 CATECHOLAMINES 4 CATECHOLAMINES IN PLASMA AND URINE ELISA 5 CATECHOLAMINES
More informationSimultaneous Quantitative Analysis of Total Catecholamines and Metanephrines in Urine Using CLEAN UP CCX2 and LC-MS/MS
Simultaneous Quantitative Analysis of Total Catecholamines and Metanephrines in Urine Using CLEAN UP CCX2 and LC-MS/MS UCT Part Numbers CUCCX256 Clean Up CCX2 (C8 + Carboxylic Acid) 500mg / 6mL SPE Cartridge
More informationAbstract. Introduction
A Fast Dilute-And-Shoot Method for Simultaneous 5-Hydroxyindoleacetic Acid (5-HIAA), Vanillylmandelic Acid (VMA), and Homovanillic Acid (HVA) LC-MS/MS Analysis in Human Urine By Shun-Hsin Liang and Sue
More informationCONVERSION OF AMINO ACIDS TO SPECIALIZED PRODUCTS DR. A. TARAB DEPT. OF BIOCHEMISTRY HKMU
CONVERSION OF AMINO ACIDS TO SPECIALIZED PRODUCTS DR. A. TARAB DEPT. OF BIOCHEMISTRY HKMU In addition to serving as building blocks for proteins, amino acids are precursors of many nitrogen-containing
More informationSimultaneous Quantitative Analysis of Total Catecholamines and Metanephrines in Urine Using 500 MG CLEAN UP CCX2 and LC-MS/MS
Simultaneous Quantitative Analysis of Total Catecholamines and Metanephrines in Urine Using 500 MG CLEAN UP CCX2 and LC-MS/MS UCT Part Numbers: CUCCX256 - Clean-Up CCX2 (C8 + Carboxylic Acid) 500mg/6mL
More informationEpinephrine/Norepinephrine ELISA Kit
Epinephrine/Norepinephrine ELISA Kit Cat. No.:DEIA3368 Pkg.Size:96T Intended use Enzyme Immunoassay for the quantitative determination of Adrenaline (Epinephrine) and Noradrenaline Norepinephrine) in plasma
More informationSuccessful implementation of online SPE LC-MS/MS in the clinical research laboratory
Successful implementation of online SPE LC-MS/MS in the clinical research laboratory Martijn van Faassen, PhD student Prof. Dr. Ido Kema University Medical Center Groningen Department of Laboratory Medicine,
More informationAnalysis of Histamine in Wine Samples Using the Microplate Format
Analysis of Histamine in Wine Samples Using the Microplate Format Introduction Bioactive amines are low molecular weight organic bases, formed by biological processes in all living organisms. One such
More informationComprehensive assessments of neuroendocrine status. Salivary Sex Steroid Hormones and Adrenal/HPA Axis Function
ENDOCRINOLOGY Comprehensive assessments of neuroendocrine status Salivary Sex Steroid Hormones and Adrenal/HPA Axis Function Neuro-Biogenic Amine and Metabolite Profiles (Neurotransmitters) Metabolomic
More informationInstructions for use. Histamine Release
Instructions for use Histamine Release Supplementary kit for the determination of the release of histamine from heparinized whole blood (this kit has to be used in combination with the Histamine ELISA,
More informationCytokines, adhesion molecules and apoptosis markers. A comprehensive product line for human and veterinary ELISAs
Cytokines, adhesion molecules and apoptosis markers A comprehensive product line for human and veterinary ELISAs IBL International s cytokine product line... is extremely comprehensive. The assays are
More informationZIVAK TECHNOLOGIES. Multitasker-LC Walk Away UHPLC Analyzer For LC-MS/MS
ZIVAK TECHNOLOGIES Multitasker-LC Walk Away UHPLC Analyzer For LC-MS/MS Clinical Diagnostic Market Roche, Siemens,Midray Abbott, Beckman Currrent Clinical Diagnostic Market Immunoassay, ELISA, RIA,FIA
More informationInstructions for Use. Dopamine - ELISA. Enzyme Immunoassay for the Quantitative Determination of. Dopamine in Plasma and Urine REF EA608/96.
Instructions for Use Dopamine - ELISA Enzyme Immunoassay for the Quantitative Determination of Dopamine in Plasma and Urine I V D REF EA608/96 12 x 8 2 8 C DLD Gesellschaft für Diagnostika und medizinische
More informationMyBioSource.com. Instructions for use. Histamine Release
Instructions for use Histamine Release Supplementary kit for the determination of the release of histamine from heparinized whole blood (this kit has to be used in combination with the Histamine ELISA,
More informationMobile Telecommunications in Kempten West Blood levels alarmingly altered
Mobile Telecommunications in Kempten West Blood levels alarmingly altered The Citizens Initiative Kempten West, which was established after the installation of the T-Mobile transmitter on the bank building
More informationTyrosine hydroxylase, the rate-limiting enzyme in catecholamine biosynthesis could be an index of functionality in pheochromocytoma diagnosis
Tyrosine hydroxylase, the rate-limiting enzyme in catecholamine biosynthesis could be an index of functionality in pheochromocytoma diagnosis Ana-Maria Stefanescu 1, *, Sorina Schipor 1, and Corin Badiu
More informationTests that have had changes to the method/ CPT code, units of measurement, scope of analysis, reference comments, or specimen requirements.
Updates In our continuing effort to provide you with the highest quality toxicology laboratory services available, we have compiled important changes regarding a number of tests we perform. Listed below
More informationSupplementary Information. Effects of Perfluorooctanoic Acid on Metabolic Profiles in Brain and Liver of Mouse by a
Supplementary Information Effects of Perfluorooctanoic Acid on Metabolic Profiles in Brain and Liver of Mouse by a High-throughput Targeted Metabolomics Approach Nanyang Yu, Si Wei, *, Meiying Li, Jingping
More informationASSAYED URINE CONTROL - LEVEL 3 (URN ASY CONTROL 3)
SSAYED URINE CONTROL - LEVEL 3 (URN ASY CONTROL 3) CAT. NO. AU 2353 LOT NO. 797UC SIZE: 12 x 10 ml EXPIRY: 2019-03 INTENDED USE This product is intended for in vitro diagnostic use, in the quality control
More informationASSAYED URINE CONTROL - LEVEL 2 (URN ASY CONTROL 2)
ASSAYED URINE CONTROL - LEVEL 2 (URN ASY CONTROL 2) CAT. NO. AU 2352 LOT NO. 718UC SIZE: 12 x 10ml EXPIRY: 2017-10 INTENDED USE This product is intended for in vitro diagnostic use in the quality control
More informationMeasures of melatonin and cortisol variations in volunteers exposed to GSM cellular phones in a double blind experiment
Article ID: WMC00634 2046-1690 Measures of melatonin and cortisol variations in volunteers exposed to GSM cellular phones in a double blind experiment Corresponding Author: Dr. Giovanna Tranfo, Senior
More informationBone and Mineral. Comprehensive Menu for the Management of Bone and Mineral Related Diseases
Bone and Mineral Comprehensive Menu for the Management of Bone and Mineral Related Diseases Innovation to Assist in Clinical Diagnosis and Treatment DiaSorin offers a specialty line of Bone and Mineral
More informationPLASMA METANEPHRINES
Blood Sciences Page 1 of 8 BS-CTG-SpecChem-20 Revision Version: 1 PLASMA METANEPHRINES INSTRUCTIONS FOR USERS AND REQUESTING CLINICIANS 1. SAMPLE REQUIREMENTS 1.1 EDTA whole blood samples are preferred
More informationOVERVIEW SALIVA, BLOOD SPOT & SERUM HORMONE PROFILES
OVERVIEW SALIVA, BLOOD SPOT & SERUM HORMONE PROFILES Abbreviations as they appear on test requisitions and test reports *Tests available in New York **Saliva & Blood Spot Saliva I Saliva II Saliva III
More informationOriginal Article. Effect of mobile usage on serum melatonin levels among medical students. Abstract. Introduction. Abha Shrivastava* and Yogesh Saxena
Indian J Physiol Pharmacol 2014; 58(4) : 395 399 Effect of Mobile Usage on Serum Melatonin Levels 395 Original Article Effect of mobile usage on serum melatonin levels among medical students Abha Shrivastava*
More informationSerotonin in Urine. Electrochemistry Discover the difference
Application Note Clinical & Diagnostics The most selective LC-EC applications for Clinical & Diagnostics analysis Catecholamines Serotonin Metanephrines VMA HVA 5-HIAA PET imaging tracer Fluorodeoxyglucose
More informationRat Leptin ELISA FOR LABORATORY USE ONLY YANAIHARA INSTITUTE INC AWAKURA, FUJINOMIYA - SHI SHIZUOKA, JAPAN
YK050 Rat Leptin ELISA FOR LABORATORY USE ONLY YANAIHARA INSTITUTE INC. 2480-1 AWAKURA, FUJINOMIYA - SHI SHIZUOKA, JAPAN 418-0011 Contents Introduction 2 Characteristics 3 Composition 4 Method 5-6 Notes
More informationENDOCRINE LABORATORY TEST REPERTOIRE
ENDOCRINE LABORATORY TEST REPERTOIRE Department of Medical Biochemistry and Immunology University Hospital of Wales Heath Park Cardiff CF14 4XW Endocrine Service Open Monday Friday 08:45 to 17:15 For general
More informationHVA, VMA and 5-HIAA in Urine
Application Note ALEXYS - Clinical & Diagnostics The soundest LC-EC Applications for Clinical & Diagnostics Analysis ever Catecholamines Serotonin Metanephrines Homocysteine Glutathione (di-)sulfides Iodide
More informationDopamine ELISA Assay Kit
Package Insert Dopamine ELISA Assay Kit 96 Wells For Research Use Only (RUO). Not for use in clinical, diagnostic or therapeutic procedures. v. 1.1 Eagle Biosciences, Inc. 20A Northwest Blvd., Suite 112,
More informationEndocrine System. True or False
True or False Endocrine System Some overweight people actually eat very little; their excess weight is caused by glands A woman who becomes anxious and depressed just before menstruating is suffering from
More informationFast, automated, precise
Thermo Scientific B R A H M S / NSE Immunodiagnostic Assays Fast, automated, precise Neuroendocrine tumor markers on KRYPTOR Systems First and only fully automated CgA assay worldwide Shortest time to
More informationCHEMILUMINESCENCE ENZYME IMMUNOASSAY (CLIA) (IgE) IgE
DIAGNOSTIC AUTOMATION, INC. 21250 Califa Street, Suite 102 and 116, Woodland Hills, California 91367 USA Tel: (818) 591-3030 Fax: (818) 591-8383 onestep@rapidtest.com technicalsupport@rapidtest.com www.rapidtest.com
More informationMetanephrine Testing Why, How and When?
Metanephrine Testing Why, How and When? Gerald Woollard & Malcolm Whiting On behalf of the Working Party on Biogenic Amines SRAC Symposium 16 rd September 2015 Olympic Park Sydney Disclaimers GW & MW members
More informationSuven Microdialysis Services
Suven Microdialysis Services In-Vivo Brain Microdialysis Studies in Rodents for Monitoring Changes in Neurotransmitters Acetylcholine Histamine and Metabolite GABA and Glutamate Monoamines (NE, DA, 5HT
More informationCHEMILUMINESCENCE ENZYME IMMUNOASSAY (CLIA) (IgE) IgE. Cat #
DIAGNOSTIC AUTOMATION, INC. 21250 Califa Street, Suite 102 and 116, Woodland Hills, California 91367 USA Tel: (818) 591-3030 Fax: (818) 591-8383 onestep@rapidtest.com technicalsupport@rapidtest.com www.rapidtest.com
More informationI. Introduction. II. Characteristics
YK050 Rat Leptin ELISA I. Introduction Leptin, which is a product of ob gene, is a protein consisting of 167 amino acids and it is secreted from white adipose tissue. It is known that leptin acts on hypothalamus
More informationC'4-tryptophan in rat pineals in organ culture. Other compounds related in
STIMULATION OF C14-MELATONIN SYNTHESIS FROM C14-TRYPTOPHAN BY NORADRENALINE IN RAT PINEAL IN ORGAN CULTURE* BY JULIUS AXELROD, HARVEY M. SHEIN, AND RICHARD J. WURTMAN LABORATORY OF CLINICAL SCIENCE, NATIONAL
More informationAdrenal Stress Profile (Saliva)
Adrenal Stress Profile (Saliva) Ireland Cortisol Levels Sample 1 Post Awakening Sample 2 (+ 4-5 Hours) Sample 3 (+ 4-5 Hours) Sample 4 (Prior to Sleep) 11.42 2.10 1.60 0.47 Sum of Cortisol 15.590 DHEA
More informationThe Integumentary System
The Integumentary System also an extension of the nervous system as it processes stimuli from the outside and sends it to the CNS Largest organ of the body Functions - regulate temperature (thermoregulation),
More informationLab Tests Made Simple
Body Fluids Commonly Used for Testing Steroid Hormones Blood Serum (venipuncture) Plasma (venipuncture) Capillary Blood (finger/heel stick) Urine Saliva Limitations of Hormone Testing in Different Body
More informationMetanephrines. in Urine. Clinical & Diagnostics Analysis. Introduction. Application Note ALEXYS - Clinical & Diagnostics
Application Note ALEXYS - Clinical & Diagnostics The soundest LC-EC Applications for Clinical & Diagnostics Analysis ever Catecholamines Serotonin nephrines VMA HVA 5-HIAA Homocysteine Glutathione (di-)sulfides
More informationHuman Aldosterone ELISA Kit
Human Aldosterone ELISA Kit Cat. No.:DEIA2002 Pkg.Size:96T Intended use For determination of Aldosterone by enzyme immunoassay in human serum by enzyme immunoassay. Hydrolysis is necessary for the determination
More informationThe analysis of Glucocorticoid Steroids in Plasma, Urine and Saliva by UPLC/MS/MS
The analysis of Glucocorticoid Steroids in Plasma, Urine and Saliva by UPLC/MS/MS Brett McWhinney, Supervising Scientist, HPLC Section, Pathology Central, Pathology Queensland Overview 1. Overview of Pathology
More informationThe Adiponectin Turbidimetric Immunoassay Reagent Kit
The Adiponectin Turbidimetric Immunoassay Reagent Kit Catalogue number: 51010 For the quantitative determination of Adiponectin in human serum and plasma This package insert must be read in its entirety
More informationAli Yaghi مها أبو عجمية. Mamon Ahram
13 Ali Yaghi مها أبو عجمية Mamon Ahram 0 P a g e This sheet is the last sheet we are supposed to study for the midterm exam. Let s begin. Biological significance of amino acids: Amino acids are used for
More informationDrug Testing Policy. Reimbursement Policy CMS Approved By. Policy Number. Annual Approval Date. Reimbursement Policy Oversight Committee
Reimbursement Policy CMS 1500 Drug Testing Policy Policy Number 2017R6005A Annual Approval Date 05/10/2017 Approved By Reimbursement Policy Oversight Committee IMPORTANT NOTE ABOUT THIS REIMBURSEMENT POLICY
More informationHigh-Throughput, Cost-Efficient LC-MS/MS Forensic Method for Measuring Buprenorphine and Norbuprenorphine in Urine
High-Throughput, Cost-Efficient LC-MS/MS Forensic Method for Measuring and in Urine Xiaolei Xie, Joe DiBussolo, Marta Kozak; Thermo Fisher Scientific, San Jose, CA Application Note 627 Key Words, norbuprenorphine,
More information24 Hour Urine Testing
24 Hour Urine ing The preferred collection container is identified in bold. Acceptable preservatives are listed that may be used when more than one test is ordered and the preferred preservatives are different
More informationMelatonin and Growth Hormone Deficiency: A Contribution to the Evaluation of Neuroendocrine Disorders
Melatonin and Growth Hormone Deficiency: A Contribution to the Evaluation of Neuroendocrine Disorders Fideleff G., Suárez M., Boquete HR, Azaretzky M., Sobrado P., Brunetto O*, Fideleff HL Endocrinology
More informationEvaluation of Endocrine Tests. C: glucagon and clonidine test in phaeochromocytoma
ORIGINAL ARTICLE Evaluation of Endocrine Tests. C: glucagon and clonidine test in phaeochromocytoma P.H. Bisschop 1*, E.P.M. Corssmit 2, S.J. Baas 1, M.J. Serlie 1, E. Endert 3, W.M. Wiersinga 1, E. Fliers
More informationRat Leptin-HS ELISA FOR LABORATORY USE ONLY YANAIHARA INSTITUTE INC AWAKURA, FUJINOMIYA - SHI SHIZUOKA, JAPAN
YK051 Rat Leptin-HS ELISA FOR LABORATORY USE ONLY YANAIHARA INSTITUTE INC. 2480-1 AWAKURA, FUJINOMIYA - SHI SHIZUOKA, JAPAN 418 0011 Contents Introduction 2 Characteristics 3 Composition 4 Method 5-6 Notes
More informationDo You Have Microwave Sickness? By. Paul Raymond Doyon MAT (TESOL), MA Advanced Japanese Studies, BA Psychology
Do You Have Microwave Sickness? By Paul Raymond Doyon MAT (TESOL), MA Advanced Japanese Studies, BA Psychology Many people have a hard time fathoming that something that they cannot see, touch, smell,
More informationNeurochemistry in Sleep and its Clinical Manifestations
Neurochemistry in Sleep and its Clinical Manifestations CATHERINE KIER, MD Professor of Clinical Pediatrics Division Chief, Pediatric Pulmonary, and Cystic Fibrosis Center Director, Pediatric Sleep Disorders
More informationImmunodiagnostic Systems
Immunodiagnostic Systems Manual Immunoassay Product Menu www.idsplc.com Vitamin D 25-Hydroxy Vitamin D EIA Enzymeimmunoassay for the quantitative IVD AC-57F1 96 Wells determination of 25-hydroxyvitamin
More informationSerotonin in Plasma. Electrochemistry Discover the difference. Summary. Application Note Clinical & Diagnostics
Application Note Clinical & Diagnostics The most selective LC-EC applications for Clinical & Diagnostics analysis Serotonin Catecholamines Serotonin Metanephrines VMA HVA 5-HIAA PET imaging tracer Fluorodeoxyglucose
More informationDRUG TESTING POLICY. Policy Number: ADMINISTRATIVE T0 Effective Date: October 1, Related Policies None
DRUG TESTING POLICY UnitedHealthcare Oxford Reimbursement Policy Policy Number: ADMINISTRATIVE 259.1 T0 Effective Date: October 1, 2017 Table of Contents Page INSTRUCTIONS FOR USE... 1 APPLICABLE LINES
More informationStress biomarker concentrations and detection in bodily fluids
NBMC BST III Workshop Arlington VA Stress biomarker concentrations and detection in bodily fluids Andrew Steckl and Prajokta Ray Nanoelectronics Laboratory, University of Cincinnati www.nanolab.uc.edu
More informationSAMPLE. dd/mm/yyyy SAMPLE. Patient Name. Patient Date of Birth. Test Analysis. Date Completed. Disclaimer
Patient Name SAMPLE Patient Date of Birth dd/mm/yyyy Test Analysis SAMPLE Date Completed Disclaimer Please note we do not provide medical advice or services. If you have health disorders, medical conditions,
More informationMercodia Equine Insulin ELISA
Mercodia Equine Insulin ELISA Directions for Use 10-1205-01 REAGENTS FOR 96 DETERMINATIONS Manufactured by Mercodia AB Sylveniusgatan 8A SE-754 50 Uppsala Sweden EXPLANATION OF SYMBOLS USED ON LABELS =
More informationHigh Epinephrine Content in the Adrenal Tumors from Sipple's Syndrome
Tohoku J. exp. Med., 1975, 115, 15-19 High Epinephrine Content in the Adrenal Tumors from Sipple's Syndrome TATSUO SATO, KIYOSHI KOBAY ASHI, YUKIO MIURA, HISAICHI SAKUMA, KAORU YOSHINAGA and KATSUHIRO
More informationProduct Catalogue 2014 / 15. Solutions for Clinical Diagnostics
Product Catalogue 214 / 15 Solutions for Clinical Diagnostics Product Catalogue 214 / 15 Date of Release: February 214 RECIPE CHEMICALS + INSTRUMENTS GmbH Dessauerstraße 3 8992 Munich/Germany Phone: +49
More informationNutritional Sleep Solutions
Nutritional Sleep Solutions Andrea Bartels, B.A., NNCP, RNT Registered Nutritional Therapist Natural Nutritional Consulting Practitioner Sleep, Nutrition and Lifestyle Why sleep? Why can t I sleep? What
More informationDiagnostic value of various biochemical parameters for the diagnosis of pheochromocytoma in patients with adrenal mass
European Journal of Endocrinology (2006) 154 409 417 ISSN 0804-4643 CLINICAL STUDY Diagnostic value of various biochemical parameters for the diagnosis of pheochromocytoma in patients with adrenal mass
More informationDRUG TESTING POLICY. Policy Number: ADMINISTRATIVE T0 Effective Date: January 1, Related Policies None
DRUG TESTING POLICY UnitedHealthcare Oxford Reimbursement Policy Policy Number: ADMINISTRATIVE 259.2 T0 Effective Date: January 1, 2018 Table of Contents Page INSTRUCTIONS FOR USE... 1 APPLICABLE LINES
More informationConversionofaminoacidsto specializedproducts
Conversionofaminoacidsto specializedproducts α-nitrogen atom of amino acids is a primary source for many nitrogenous compounds: Heme Purines and pyrimidines Hormones Neurotransmitters Biologically active
More informationPart 2: How Your Brain and Nervous System Work
Part 2: How Your Brain and Nervous System Work with Dr. Ritamarie Loscalzo Medical Disclaimer: The information in this presentation is not intended to replace a one onone relationship with a qualified
More informationDISTRIBUTION STATEMENT A. Approved for public release; distribution is unlimited.
DISTRIBUTION STATEMENT A. Approved for public release; distribution is unlimited. Investigation of the Physiological Responses of Belugas to Stressors to Aid in Assessing the Impact of Environmental and
More informationAutomated Determination of VMA, HVA, 5 HIAA in Urine Using the
Automated Determination of VMA, HVA, 5 HIAA in Urine Using the Gilson GX 274 ASPEC and Gilson ASPEC XL Application Note CL0111 Keywords Gilson GX 274 ASPEC, TRILUTION LH, Catecholamines, Urine, Vanillylmandelic
More informationThe Endocrine response to Stress. Dr. Sajeda Al-Chalabi Assistant Professor Head of Dept. Of Physiology
The Endocrine response to Stress Dr. Sajeda Al-Chalabi Assistant Professor Head of Dept. Of Physiology The Physiology of Stress A series of neural and chemical reactions meant for physical survival
More informationHuman Thyroid Stimulating Hormone CLIA kit
Human Thyroid Stimulating Hormone CLIA kit Cat. No.:DEEL0223 Pkg.Size:96 tests Intended use For the direct quantitative determination of Thyroid Stimulating Hormone in human serum by chemiluminescence
More informationPatient Fernand Ovellette 1014 Smythe St Fredericton, NB E2B 3H2 CANADA 2:00 PM 4/19/10 6:00 AM 4/19/10 6:00 PM 4/19/10 8:00 AM 4/19/10
NeuroScience Inc. - Report 43546 (Fernand Ovellette) Page of 3 Report Information Health Care Professional Integrative Psychiatry 3392 Magic Oak Lane Sarasota, FL 34232 Order Details Improving Health Through
More informationIntroduction to hormones & neurotransmitters. Prof K Syed Department of Biochemistry & Microbiology University of Zululand Room no.
Introduction to hormones & neurotransmitters Prof K Syed Department of Biochemistry & Microbiology University of Zululand Room no. 247 Topics Major systems of human body Glands Hormones vs neurotransmitters
More informationVGKC-Autoantibody Assay RIA
Instructions for Use VGKC-Autoantibody Assay RIA 125I-Radio Immuno Assay for the Quantitative Determination of Antibodies to the Voltage-Gated Potassium Channel (VGKC) in Serum I V D REF RA115/25 25 2
More informationRole of Tyk-2 in Th9 and Th17 cells in allergic asthma
Supplementary File Role of Tyk-2 in Th9 and Th17 cells in allergic asthma Caroline Übel 1*, Anna Graser 1*, Sonja Koch 1, Ralf J. Rieker 2, Hans A. Lehr 3, Mathias Müller 4 and Susetta Finotto 1** 1 Laboratory
More informationDrug Testing Policy. Approved By 05/10/2017. Application This reimbursement policy applies to UnitedHealthcare Community Plan Medicaid products.
Policy Number 2017R6005B Annual Approval Date Drug Testing Policy 05/10/2017 Approved By Reimbursement Policy Oversight Committee IMPORTANT NOTE ABOUT THIS REIMBURSEMENT POLICY You are responsible for
More informationValidation Report for the Neogen Fentanyl Kit for ELISA Screening of Whole Blood and Urine Specimens
Validation Report for the Neogen Fentanyl Kit for ELISA Screening of Whole Blood and Urine Specimens This document describes the validation of a Neogen Fentanyl kit for the semi-quantitative analysis of
More informationLipase Assay Kit. Catalog Number KA assays Version: 02. Intended for research use only.
Lipase Assay Kit Catalog Number KA1654 100 assays Version: 02 Intended for research use only www.abnova.com Table of Contents Introduction... 3 Intended Use... 3 Principle of the Assay... 3 General Information...
More informationEXOTESTTM. ELISA assay for exosome capture, quantification and characterization from cell culture supernatants and biological fluids
DATA SHEET EXOTESTTM ELISA assay for exosome capture, quantification and characterization from cell culture supernatants and biological fluids INTRODUCTION Exosomes are small endosome-derived lipid nanoparticles
More informationYour Reported Urinary Free Cortisone Pattern
P: 1300 688 522 E: info@nutripath.com.au A: PO Box 442 Ashburton VIC 3142 TEST PATIENT Sex : D Collected : 00-00-0000 111 ROAD TEST SUBURB AB : 00000000 UR#:0000000 TEST PHYSICIAN DR JOHN DOE 111 CLINIC
More informationSCIEX Vitamin D 200M Assay for the Topaz System
The First FDA-Cleared LC-MS/MS Assay for Vitamin D SCIEX Vitamin D 200M Assay for the Topaz System The first FDA-cleared LC-MS/MS assay for Vitamin D Vitamin D is an important building block for human
More informationHomeostasis. Endocrine System Nervous System
Homeostasis Endocrine System Nervous System 2004-2005 Regulation Why are hormones needed? chemical messages from one body part to another communication needed to coordinate whole body homeostasis & regulation
More informationDRUG TESTING POLICY. Policy Number: ADMINISTRATIVE T0 Effective Date: March 1, Related Policies None
DRUG TESTING POLICY UnitedHealthcare Oxford Reimbursement Policy Policy Number: ADMINISTRATIVE 259.3 T0 Effective Date: March 1, 2018 Table of Contents Page INSTRUCTIONS FOR USE... 1 APPLICABLE LINES OF
More informationPheochromocytoma Diagnosis Update
A U t U M N 2 0 1 6 # 2 Inside This Issue PHEOCHROMOCYTOMA DIAGNOSIS UPDATE...1 CYTOLOGY PEARLS...4 TECHNICIAN S CORNER...5 THREE ONLINE WAYS TO ACCESS MARSHFIELD LABS VETERINARY SERVICES...6 Pheochromocytoma
More informationYK052 Mouse Leptin ELISA
YK052 Mouse Leptin ELISA FOR LABORATORY USE ONLY YANAIHARA INSTITUTE INC. 2480-1 AWAKURA, FUJINOMIYA-SHI SHIZUOKA, JAPAN 418-0011 Contents Ⅰ. Introduction 2 Ⅱ. Characteristics 3 Ⅲ. Composition 4 Ⅳ. Method
More informationcolorimetric sandwich ELISA kit datasheet
colorimetric sandwich ELISA kit datasheet For the quantitative detection of human IL5 in serum, plasma, cell culture supernatants and urine. general information Catalogue Number Product Name Species cross-reactivity
More informationAdrenal Medulla. Amelyn R. Rafael, M.D.
Adrenal Medulla Amelyn R. Rafael, M.D. Adrenal Medulla Exodermal in origin Cells derived from the sympathogonia of the primitive neuroectoderm A sympathetic ganglion in which the post-ganglionic cells
More informationNutrition: obtaining reliable biomarker data to study the health status of populations
Nutrition: obtaining reliable biomarker data to study the health status of populations Christine M. Pfeiffer, Ph.D. Chief, Nutritional Biomarkers Branch, DLS AAAS 2011 Annual Meeting Science Without Borders
More informationSteroid Hormone Perturbation. Jeff Lawrence
Investigative and Predictive Approaches to Drug-Induced Steroid Hormone Perturbation Jeff Lawrence Comparative Biology and Safety Sciences Nor Cal SOT 4-Nov-21 Understanding Mechanisms Helps Provide a
More informationCircadian rhythm and Sleep. Radwan Banimustafa MD
Circadian rhythm and Sleep Radwan Banimustafa MD Homeostasis Maintenance of equilibrium by active regulation of internal states: Cardiovascular function (blood pressure, heart rate) Body temperature Food
More informationAll stocks and calibration levels were prepared in water: methanol (50:50) v/v to cover range of all steroid concentrations (refer Table 1).
Application LCMS-8040 Simultaneous determination of 11 steroids and Vitamin D2/D3 in human serum using LC/MS/MS - Introduction Quantification of endogenous hormonal steroids and their precursors is essential
More information6/2/2014 THE VALUE OF REST AND THE FUTURE OF SUPPORTING HEALTHY SLEEP PATTERNS. How Important is Sleep? Your Wellness Program :
THE VALUE OF REST AND THE FUTURE OF SUPPORTING HEALTHY SLEEP PATTERNS Scott Theirl, DC, DACNB, FACFN Diplomate- American Chiropractic Neurology Board Fellow- American College of Functional Neurology How
More informationSYSTEMATIC REVIEW PROTOCOL FOR ANIMAL INTERVENTION STUDIES
SYSTEMATIC REVIEW PROTOCOL FOR ANIMAL INTERVENTION STUDIES Item # Section/Subsection/Item A. General 1. Title of the review 2. Authors (names, affiliations, contributions) FORMAT BY SYRCLE (WWW.SYRCLE.NL)
More informationDBC s panel of thyroid hormone immunoassays is now more comprehensive with the new Reverse T3 ELISA kit. Test Your Hormones
DBC s panel of thyroid hormone immunoassays is now more comprehensive with the new Reverse T3 ELISA kit Test Your Hormones INTRODUCTION For years thyroid hormone testing has been concentrated on TSH and
More informationINTEGRATIVE MEDICINE URINE, SPOT Result Range Units
D Collected : 00-00-0000 INTEGRATIVE MEDICINE URINE, SPOT Result Range Units Intermediate Neurotransmitter Profile Glycine, Urine 48.0 43.0-173 mmol/molcr Inhibitory Neurotransmitters SEROTONIN Urine 73.3
More informationExtraction of Multiple Mycotoxins From Nuts Using ISOLUTE Myco prior to LC-MS/MS Analysis
Application Note AN784 Extraction of Multiple Mycotoxins from Nuts Using ISOLUTE Myco Page 1 Extraction of Multiple Mycotoxins From Nuts Using ISOLUTE Myco prior to LC-MS/MS Analysis This application note
More informationHuman Total GIP Kit v1-2016Apr 1
Human Total GIP Kit 1-Plate Kit 5-Plate Kit 25-Plate Kit K151RPD-1 K151RPD-2 K151RPD-4 18067-v1-2016Apr 1 MSD Metabolic Assays Human Total GIP Kit This package insert must be read in its entirety before
More informationInternal Use The form of MSM available for internal use is powder or crystalline, but can be mixed in food or beverages if you prefer.
MSM USAGE GUIDE How to Use MSM Which MSM should I use? There are certain grades of MSM that are used for livestock consumption. However, you want to look for MSM manufactured under the name "Pure MSM".
More informationAntidepressants: Prof. Riyadh Al_Azzawi F.R.C.Psych
Antidepressants: Prof. Riyadh Al_Azzawi F.R.C.Psych A. Heterocyclic antidepressants: (tricyclic and tetracyclic ), e.g.amitryptaline,imipramine. B. Monoamine oxidase inhibitors(m.a.o.i), e.g.phenelzine.
More information