NEURORADIOLOGY. Part III. Angela Csomor University of Szeged Department of Radiology

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1 NEURORADIOLOGY Part III Angela Csomor University of Szeged Department of Radiology

2 DISEASES OF SPINE AND SPINAL CORD I. Non-tumourous diseases developmental anomalies vascular disorders inflammatory processes II. Tumours extradural intradural - extramedullary intramedullary degenerative changes trauma

3 SPINE AND SPINAL CORD - imaging methods Plain film radiography Ultrasonography Computer tomography (CT) Magnetic resonance imaging (MRI) Digital subtraction angiography (DSA) Myelography

4 Imaging modalities - indications Plain film radiography developmental anomalies: bone inflammations: spondylitis / spondylodiscitis degenerative: spondylarthrosis trauma: fractures / dislocations tumours: bone changes

5 Imaging modalities - indications Computer tomography (CT) developmental anomalies: bones / spinal canal inflammations: bones / discs degenerative changes: spondylarthrosis, disc herniations trauma: bones, epi - subdural haemorrhages tumours: bone changes Myelo-CT trauma: dural and radicular injuries etc.

6 Imaging modalities - indications Magnetic resonance imaging (MRI) spinal cord lesions: all developmental anomalies vascular disorders inflammatory processes degenerative diseases: disc herniations trauma: intramedullary lesions, haemorrhages tumours

7 Imaging modalities - indications Digital subtraction angiography (DSA) preoperative dg, diff.dg vascular malformations hypervascularized tumours intervention (embolisation) vascular malformations hypervascularised tumours

8 DISEASES OF SPINE AND SPINAL CORD I. Non-tumourous diseases developmental anomalies vascular disorders inflammatory processes II. Tumours extradural intradural - extramedullary intramedullary degenerative changes trauma

9 Developmental anomalies Often complex Involves more structures bones meninges tethered cord, lipoma, spina bifida dermal sinus spinal cord

10 Chiari malformations

11 Developmental anomalies Often complex bones meninges spinal cord Longitudinal split in the spinal cord Osseous/ cartilaginous spur Diastematomyelia with block vertebrae

12 L.V. hypoplasia Developmental anomalies Spondylolisthesis, lysis

13 Developmental anomalies Arachnoidal cyst closed liquor space no CSF flow

14 DISEASES OF SPINE AND SPINAL CORD I. Non-tumourous diseases developmental anomalies vascular disorders inflammatory processes II. Tumours extradural intradural - extramedullary intramedullary degenerative changes trauma

15 Vascular disorders Developmental malformations Dilated, tortuoos veins and stasis Neurological symptomes-slowly Treatment: embolization/surgery Diagnose in early stage! Spinal dural AV fistula

16 Vascular disorders Developmental malformations Cavernoma blood filled vascular spaces

17 Vascular disorders Developmental malformations Acquired Infarcts Vascular territory Symptomes sudden onset progression

18 DISEASES OF SPINE AND SPINAL CORD I. Non-tumourous diseases developmental anomalies vascular disorders inflammatory processes II. Tumours extradural intradural - extramedullary intramedullary degenerative changes trauma

19 Inflammatory processes Spondylitis/spondylodiscitis: two vertebrae and the disc betwen them narrow iv.space irregular vertebral endplates epidural abscess

20 Inflammatory processes Spondylodiscitis Meningitis, abscess Myelitis/ myelopathy

21 Myelopathy pathological conditions of the spinal cord High intensity on T2 Causes Vascular AV fistula, ischaemia Inflammation SM, Devic, ADEM Degenerative cord Compression Trauma Tumor

22 Localisation Diameter Length Enhancement Cord swelling Myelopathy

23 Myelopathy pathological conditions of the spinal cord High intensity on T2 Causes Vascular AV fistula long segmen most of the diameter swelling+ (acut) Ischaemia long segment vascular territory swelling+ (acut)

24 Myelopathy pathological conditions of the spinal cord Causes Inflammation SM, Devic, ADEM less than three segment less than half of the diameter swelling+/- enhancement +/-

25 Neuromyelitis optica Devic Optic neuritis + Myelitis Months / years between them Relapsing, autoimmun long segmen most of the diameter swelling+ (acut) enhancement +/-

26 Acute disseminated encephalomyelitis ADEM After viral infection or vaccination immune mediated Brain and/or spinal cord Multiple Monophasic Usually complete recovery long segmen most of the diameter swelling + enhancement -

27 Myelopathy B12 deficiency Degenerative cord Posterior part, both side

28 DISEASES OF SPINE AND SPINAL CORD I. Non-tumourous diseases developmental anomalies vascular disorders inflammatory processes II. Tumours extradural intradural - extramedullary intramedullary degenerative changes trauma

29 Myelopathy pathological conditions of the spinal cord High intensity on T2 Causes Vascular AV fistula, ischaemia Inflammation SM, Devic, ADEM Degenerative cord Compression Trauma Tumor

30 Degenerative changes Spondylarthrosis Disc herniations Spinal canal, iv. foramen diameter affected bones ligaments disc

31 Degenerative changes

32 Degenerative changes Disc herniations CT MR

33 Degenerative changes Disc herniations - locations medial paramedial lateral (foraminal and extraforaminal)

34 Disc herniation

35 Degenerative changes Disc herniations postoperative scar/residual disc scar enhancement- 2 years Preop. Postop.

36 Pars interarticularis defect Degenerativ spondylosis Spondylolisthesis, lysis

37 DISEASES OF SPINE AND SPINAL CORD I. Non-tumourous diseases developmental anomalies vascular disorders inflammatory processes II. Tumours extradural intradural - extramedullary intramedullary degenerative changes trauma

38 Traumatic lesions Fractures/dislocations Haemorrhages Spinal cord injuries Dural tear/root avulsion

39 CT

40

41 Vertebral compression percutaneous vertebroplasty Metastasis, osteoporosis bone cement is injected fluoroscopic X-ray guidance pain relief vertebral height consolidation

42 Ligamentous injury / instability

43 Atlantoaxial instability

44 Traumatic lesions Fractures/dislocations Haemorrhages Spinal cord injuries Dural tear/root avulsion

45 Traumatic lesions Fractures/dislocations Haemorrhages Spinal cord injuries Dural tear/root avulsion

46 MR Spinal cord compression

47 Trauma/spinal stenosis 1 year later

48 DISEASES OF SPINE AND SPINAL CORD I. Non-tumourous diseases developmental anomalies vascular disorders inflammatory processes II. Tumours extradural intradural - extramedullary intramedullary degenerative changes trauma

49 Tumours Extradural bone tumours metastases Intradural - extramedullary meningiomas Neurinomas metastases Intramedullary astrocytomas ependymomas Haemangioblastomas metastases

50 Tumours Extradural bone tumours bone metastases Intradural - extramedullary meningiomas Neurinomas metastases Intramedullary astrocytomas ependymomas Haemangioblastomas metastases

51 Tumours Extradural bone tumours bone metastases Intradural - extramedullary meningiomas Neurinomas metastases Intramedullary astrocytomas ependymomas Haemangioblastomas metastases Spinal cord compression

52 Tumours Extradural bone tumours metastases Intradural - extramedullary meningiomas Neurinomas metastases Intramedullary astrocytomas ependymomas Haemangioblastomas metastases

53 Tumours Extradural bone tumours metastases Intradural - extramedullary meningiomas Neurinomas/Neurofibromatosis metastases Intramedullary astrocytomas ependymomas Haemangioblastomas metastases

54 Tumorok Extradural bone tumours metastases Intradural - extramedullary meningiomas Neurinomas/Neurofibromatosis metastases Intramedullary astrocytomas ependymomas Haemangioblastomas metastases Medulloblastoma drop metastasis

55 Tumours Extradural bone tumours metastases Intradural/extramedullary meningiomas Neurinomas metastases Intramedullary astrocytomas ependymomas Haemangioblastomas metastases Cystic + enhancing part+ syringomyelia

56 Intramedullary astrocytoma

57 Tumours Extradural bone tumours metastases Intradural - extramedullary meningiomas Neurinomas metastases Intramedullary astrocytomas ependymomas Haemangioblastomas metastases

58 von Hippel-Lindau disease

59 Tumours Extradural bone tumours metastases Intradural - extramedullary meningiomas Neurinomas metastases Intramedullary astrocytomas ependymomas Haemangioblastomas metastases Melanoma metastases Hodi FS et al. (2008) Nat Clin Pract Oncol doi: /ncponc1183

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