Dr Matthew Strack. Dermatologist Christchurch Dunedin Invercargill

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1 Dr Matthew Strack Dermatologist Christchurch Dunedin Invercargill 14:00-14:55 WS #33: Managing Melanoma - Guidelines and Controversies 15:05-16:00 WS #43: Managing Melanoma - Guidelines and Controversies (Repeated)

2 Melanoma Management Quiz Dr Matthew Strack Dermatologist 360 Papanui Rd Marinoto Clinic, Mercy Hospital Christchurch Dunedin

3 Melanoma in Community Practice Suspected Melanoma Management Excision Guidelines Follow up Issues

4 Q1. % of Melanomas in New Zealand either in situ or <1mm? A. <75% B % C % D. > 95% E. Unknown Letter: Timeliness of melanoma management New Zealand Medical Journal 15th December 2017, Volume 130 Number 1467 Keith Monnington, Sharad Paul, Dirk Venter URL:

5 % of Melanomas in New Zealand either in situ or <1mm? A. <75% B % C % D. > 95% E. Unknown Letter: Timeliness of melanoma management New Zealand Medical Journal 15th December 2017, Volume 130 Number 1467 Keith Monnington, Sharad Paul, Dirk Venter URL:

6

7 Q2. You excise a suspected melanoma; histology confirms a benign lesion. Your next action is: A. Ring patient with good news B. Write a formal letter of apology C. Contact your medical insurer for advice D. Depends what you said prior to surgery E. Immediately refund fee for surgery and consider B. or C.

8 You excise a suspected melanoma; histology confirms a benign lesion. Your next action is: A. Ring patient with good news B. Write a formal letter of apology C. Contact your medical insurer for advice D. Depends what you said prior to surgery E. Immediately refund fee for surgery and consider B. or C.

9 1:5-10 Number needed to treat

10 Q3. Recommended excision margins for <1mm Melanoma A. 5mm B. 10mm C mm D. 20mm E. Guidelines not clear or not published F. Depends on other Factors

11 Recommended excision margins for <1mm Melanoma A. 5mm B. 10mm C mm D. 20mm E. Guidelines not clear or not published F. Depends on other Factors

12 Q4. Recommended excision margins for 1-2mm Melanoma A. 5mm B. 10mm C mm D. 20mm E. Guidelines not clear or not published F. Depends on other Factors

13 Recommended excision margins for 1-2mm Melanoma A. 5mm B. 10mm C mm D. 20mm E. Guidelines not clear or not published F. Depends on other Factors

14 Q5. Recommended excision margins for 2-4mm Melanoma A. 5mm B. 10mm C mm D. 20mm E. Guidelines not clear or not published F. Depends on other Factors

15 Recommended excision margins for 2-4mm Melanoma A. 5mm B. 10mm C mm D. 20mm E. Guidelines not clear or not published F. Depends on other Factors

16 Q6. Recommended excision margins for Acral and Subungual Melanoma A. 5mm B. 10mm C mm D. 20mm E. Guidelines not clear or not published F. Depends on other Factors

17 Recommended excision margins for Acral and SubUngual Melanoma A. 5mm B. 10mm C mm D. 20mm E. Guidelines not clear or not published F. Depends on other Factors

18 Q7. Recommended excision margins for In-Situ Melanoma A. 5mm B. 10mm C mm D. 20mm E. No guidelines exist F. Depends on other Factors

19 Recommended excision margins for In-Situ Melanoma A. 5mm B. 10mm C mm D. 20mm E. No guidelines exist F. Depends on other Factors

20 Q8. You suspect a lesion has low risk of melanoma (5% or less). You plan to: A. Excise with 20mm margins B. Ask patient to keep an eye on it C. Refer for second opinion D. Reschedule review in 6 months E. Book incisional or punch biopsy

21 You suspect a lesion has low risk of melanoma (5% or less). You plan to: A. Excise with 20mm margins B. Ask patient to keep an eye on it C. Refer for second opinion D. Reschedule review in 6 months E. Book incisional or punch biopsy

22 Q9. You suspect a lesion has very low risk of melanoma (less than 1%). You plan to: A. Reassure Patient B. Ask patient to keep an eye on it C. Refer for second opinion D. Reschedule review in 6 months E. Book incisional or punch biopsy

23 You suspect a lesion has very low risk of melanoma (less than 1%). You plan to: A. Reassure Patient B. Ask patient to keep an eye on it C. Refer for second opinion D. Reschedule review in 6 months E. Book incisional or punch biopsy

24 Surface Cell Adhesive Sample Analysis

25 Q10. You are confident that a lesion is benign. You plan to: A. Reassure Patient B. Ask patient to keep an eye on it C. Refer for second opinion D. Reschedule review in 6 months E. Book incisional or punch biopsy

26 You are confident that a lesion is benign. You plan to: A. Reassure Patient B. Ask patient to keep an eye on it C. Refer for second opinion D. Reschedule review in 6 months E. Book incisional or punch biopsy

27 Q11. Sentinel Lymph Node Biopsy Threshold: A. In-Situ B. 0.5mm C. 1mm D. 1.5mm E. 2mm and greater

28 Sentinel Lymph Node Biopsy Threshold: A. In-Situ B. 0.5mm C. 1mm D. 1.5mm E. 2mm and greater

29 Liquid Biopsy

30 Q12. You excise a suspected melanoma with measured 5mm margins, it is reported as radial growth phase / melanoma in-situ with 5mm clear margins. Your next action: A. No Re-excision Necessary B. Re-excise with 5mm margins C. Re-excise with 1-2cm margins D. Refer to specialist for re-excision E. Request MRI of area

31 You excise a suspected melanoma with measured 5mm margins, it is reported as radial growth phase / melanoma in-situ with 5mm clear margins. Your next action: A. No Re-excision Necessary B. Re-excise with 5mm margins C. Re-excise with 1-2cm margins D. Refer to specialist for re-excision E. Request MRI of area

32 Q13. You excise a suspected melanoma with measured 5mm margins, it is reported as 0.7mm invasive melanoma with 5mm clear margins. Your next action: A. No Re-excision Necessary B. Re-excise with 5mm margins C. Re-excise with 1-2cm margins D. Refer to specialist for re-excision E. Request MRI of area

33 You excise a suspected melanoma with measured 5mm margins, it is reported as 0.7mm invasive melanoma with 5mm clear margins. Your next action: A. No Re-excision Necessary B. Re-excise with 5mm margins C. Re-excise with 1-2cm margins D. Refer to specialist for re-excision E. Request MRI of area

34 Q14. You excise a suspected melanoma with measured 10mm margins, it is reported as 1.1mm invasive melanoma with 5mm clear margins. Your next action: A. No Re-excision Necessary B. Re-excise with 5mm margins C. Re-excise with 1-2cm margins D. Refer to specialist for re-excision E. Request MRI of area

35 You excise a suspected melanoma with measured 10mm margins, it is reported as 1.1mm invasive melanoma with 5mm clear margins. Your next action: A. No Re-excision Necessary B. Re-excise with 5mm margins C. Re-excise with 1-2cm margins D. Refer to specialist for re-excision E. Request MRI of area

36 Q15. Melanoma Follow Up A. Patients should be seen by Doctor B. Not shown to Increase Survival C. Recurrences usually detected by patient rather than Doctor D. Frequency/Intervals can be negotiated on a case to case basis E. All of the above

37 Melanoma Follow Up A. Patients should be seen by Doctor B. Not shown to Increase Survival C. Recurrences usually detected by patient rather than Doctor D. Frequency/Intervals can be negotiated on a case to case basis E. All of the above

38 Q16. Recommended Follow up Intervals In-Situ and <1mm Melanoma A. 3-4 monthly for 5years B. 6 monthly for 5 years C. Annually for 5 years D. 3-4 monthly for 3 years then annually until 5 years E. 6 monthly for 2 years then annually until 5 years F. To determine with patient on a case by case basis

39 Recommended Follow up Intervals In-Situ and <1mm Melanoma A. 3-4 monthly for 5years B. 6 monthly for 5 years C. Annually for 5 years D. 3-4 monthly for 3 years then annually until 5 years E. 6 monthly for 2 years then annually until 5 years F. To determine with patient on a case by case basis

40 Q17. Recommended Follow up Intervals 1-4mm Melanoma A. 3-4 monthly for 5years B. 6 monthly for 5 years C. Annually for 5 years D. 3-4 monthly for 3 years then annually until 5 years E. 6 monthly for 2 years then annually until 5 years F. To determine with patient on a case by case basis

41 Recommended Follow up Intervals 1-4mm Melanoma A. 3-4 monthly for 5years B. 6 monthly for 5 years C. Annually for 5 years D. 3-4 monthly for 3 years then annually until 5 years E. 6 monthly for 2 years then annually until 5 years F. To determine with patient on a case by case basis

42 Q18. Sun Protection post Melanoma A. Parabens are not a problem in sunblock anymore B. Vitamin D deficiency may be a problem C. Outdoors workers may need to change job D. Patients should have a general skin check to document sun damage (amongst other things) at time of diagnosis E. All of the above

43 Sun Protection post Melanoma A. Parabens are not a problem in sunblock anymore B. Vitamin D deficiency may be a problem C. Outdoors workers may need to change job D. Patients should have a general skin check to document sun damage (amongst other things) at time of diagnosis E. All of the above

44 New York Times, 3 May 2018 Hawaii Passes Bill Banning Sunscreen That Can Harm Coral Reefs The legislation prohibits the distribution of sunscreens containing chemicals that scientists have found contributes to coral bleaching when washed off in the ocean. oxybenzone octinoxate

45 Q19. Vitamin D issues A. Patients with low vitamin D should have Vitamin D orally B. Vitamin D test is available free of charge at the lab C. Vitamin D supplements are usually necessary D. We do not know the normal or optimum range for vitamin D E. Patients should be encouraged to get out in the sun to make natural vitamin D

46 Vitamin D issues A. Patients with low vitamin D should have Vitamin D orally B. Vitamin D test is available free of charge at the lab C. Vitamin D supplements are usually necessary D. We do not know the normal or optimum range for vitamin D E. Patients should be encouraged to get out in the sun to make natural vitamin D

47 Q20. Side Effects of Excess Vitamin D A. Hypercalcaemia B. Kidney Stones C. Constipation D. ECG / Heart Rhythm Changes E. All of the above

48 Side Effects of Excess Vitamin D A. Hypercalcaemia B. Kidney Stones C. Constipation D. ECG / Heart Rhythm Changes E. All of the above

49 Base Transection with Shave Biopsy Breslow Thickness vs Transection Rate <1mm 45% 1-4mm 75% >4mm 92%

50 New Treatments Spokeswoman: Jimmy Carter no longer needs cancer treatment

51 Matthew Strack

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