List of publications - Pernilla Lagergren
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1 List of publications - Pernilla Lagergren 1. Toxopeus E, van der Schaaf M, van Lanschot J, Lagergren J, Lagergren P, van der Gaast A, Wijnhoven B. Outcome of Patients Treated Within and Outside a Randomized Clinical Trial on Neoadjuvant Chemoradiotherapy Plus Surgery for Esophageal Cancer: Extrapolation of a Randomized Clinical Trial (CROSS). Ann Surg Oncol Aug;25(8): PMID: Sunde B, Johnsen G, Jacobsen AB, Glenjen NI, Friesland S, Lindblad M, Rouvelas I, Wang N, Lundell L, Lagergren P, Nilsson M. Effects of neoadjuvant chemoradiotherapy vs chemotherapy alone on the relief of dysphagia in esophageal cancer patients: secondary endpoint analysis in a randomized trial. Dis Esophagus Aug 1. [Epub ahead of print] PMID: Schandl A, Johar A, Mälberg K, Lagergren P. Education level and health-related quality of life after oesophageal cancer surgery a nationwide cohort study. BMJ Open 2018 Aug 23;8(8):e Kauppila J, Ringborg C, Johar A, Lagergren J, Lagergren P. Health-related quality of life after gastrectomy, esophagectomy, and combined esphagogastrectomy for gastroesophageal junction adenocarcinoma. Gastric Cancer 2018 May; 21(3): PMID: Anandavadivelan P. Wikman A, Johar A, Lagergren P. Profiles of patient and tumour characteristics in relation to health-related quality of life after oesophageal cancer surgery. PLoS One 2018 Apr 30;13(4):e PMID: Anandavadivelan P. Wikman A, Johar A, Lagergren P. Impact of weight loss and eating difficulties on health related quality of life up to 10 years after oesophagectomy for cancer. Br J Surg 2018;105: PMID: Kauppila J, Wahlin K, Lagergren P, Lagergren J. University hospital status and surgeon volume and risk of reoperation following surgery for esophageal cancer. Eur J Surg Oncol 2018 May;44(5): PMID: Markar SR, Johar A, Maisey N, Lagergren P, Lagergren J. Complications during neoadjuvant therapy and prognosis following surgery for esophageal cancer. Dis Esophagus 2017 Dec 22 PMID: Kauppila J, Wahlin K, Lagergren P, Lagergren J. Neoadjuvant therapy in relation to lympadenectomy and resection margins during surgery for oesophageal cancer. Scientific Reports 2018 Jan 11;8(1):446
2 PMID: Kauppila J, Johar A, Gossage J, Davies A, Zylstra J, Lagergren J, Lagergren P. Healthrelated quality of life after open transhiatal and transthoracic surgery for oesophageal cancer. Br J Surg 2018 Feb;105(3): PMID: Smyth E C, Lagergren J, Fitzgerald R C, Lordick F, Shah M A, Lagergren P, Cunningham D. Oesophageal cancer. Nature Reviews Disease Primers 2017 Jul 27;3:17048 PMID: Lagergren J, Mattsson F, Lagergren P. Prognosis following cancer surgery during holiday periods. Int J Cancer Jul 21. doi: /ijc [Epub ahead of print] PMID: Hynes O, Anandavadivelan P, Gossage J, Johar A, Lagergren J, Lagergren P. The impact of pre-and post-operative weight loss and body mass index on prognosis in patients with oesophageal cancer. Eur Journal Surg Oncol 2017 Aug;43(8): PMID: Lagergren J, Mattsson F, Lagergren P. Weekday of oesophageal cancer surgery in relation to early postoperative outcomes in a nationwide Swedish cohort study. BMJ Open May 31;6(5):e PMID: Lagergren J, Smyth E, Cunningham D, Lagergren P. Oesophageal cancer: Seminar. Lancet 2017;25;390(10110): PMID: Markar S, Mackenzie H, Lagergren P, Lagergren J. Surgeon age in relation to prognosis after esophageal cancer resection. Annals of Surgery 2017 Apr 7 PMID: Kauppila JH, Xie S, Johar A, Markar S, Lagergren P. Meta-analysis of health-related quality of life after minimally invasive versus open oesophagectomy for oesophageal cancer. British Journal of Surgery 2017 Aug;104(9): PMID: Rutegård M, Lagergren P, Johar A, Rouvelas I, Lagergren J. The prognostic role of coeliac node metastasis after resection for distal oesophageal cancer. Scientific Reports 2017 Mar 3;7:43744 PMID: Hellstadius Y, Lagergren J, Zylstra J, Gossage J, Davies A, Hultman C, Lagergren P, Wikman A. A longitudinal assessment of psychological distress after oesophageal cancer surgery. Acta Oncologica 2017 May;56(5): PMID:
3 20. Lagergren J, Mattsson F, Davies A, Lindblad M, Lagergren P. Lymphadenectomy and risk of reoperation or mortality shortly after surgery for oesophageal cancer. Scientific Report 2016 Oct 31;6: PMID: Schandl A, Lagergren J, Johar A, Lagergren P. Health-related quality of life 10 years after oesophageal cancer surgery. European Journal of Cancer 2016 Dec;69: PMID: Markar S, Wahlin K, Mattson F, Lagergren P, Lagergren J. Surgery during holiday periods and prognosis in oesophageal cancer - a population-based nationwide Swedish cohort study. BMJ Open 2016 Sep 6;6(9):e PMID: Schandl A, Johar A, Lagergren J, Lagergren P. Lymphadenectomy and health-related quality of life after oesophageal cancer surgery: a nationwide, population-based cohort study. BMJ Open 2016 Aug 26;6(8):e PMID: Markar S, Mavroveli S, Petrides KV, Scarpa M, Christophe V, Castoro C, Mariette C, Lagergren P, Hanna GB. Applied investigation of person-specific and context-specific factors on postoperative recovery and clinical outcomes of patients undergoing gastrointestinal cancer surgery: multicentre European study. BMJ Open 2016 Oct 24;6(10):e PMID: Markar S, Wahlin K, Lagergren P, Lagergren J. University hospital status and prognosis following surgery for esophageal cancer. Eur J Surg Oncol 2016 Aug;42(8): PMID: Backemar L, Wikman A, Djärv T, Johar A, Lagergren P. Co-morbidity after oesophageal cancer surgery and recovery of health-related quality of life. Br J Surg Nov;103(12): PMID: Martin L, Lagergren J, Blomberg J, Johar A, Bosaeus I, Lagergren P. Phase angle as a prognostic marker after percutaneous endoscopic gastrostomy (PEG) in a prospective cohort study. Scandinavian Journal of Gastroenterology 2016 Aug;51(8): PMID: Markar S, Mackenzie H, Lagergren P, Hanna GB, Lagergren J. Surgical proficiency gain and survival following esophagectomy for cancer. J Clin Oncol 2016;34(13): PMID: Lagergren J, Mattsson F, Lagergren P. Weekday of esophageal cancer surgery and its relation to prognosis. Ann Surg 2016 Jun;263(6):
4 PMID: Anandavadivelan P, Lagergren P. Cachexia in patients with oesophageal cancer. Nat Rev Clin Oncol 2016;13(3): PMID: Lagergren J, Mattsson F, Zylstra J, Chang F, Gossage J, Mason R, Lagergren P, Davies A. Extent of Lymphadenectomy and Prognosis After Esophageal Cancer Surgery. JAMA Surgery (1):32-9 PMID: Hellstadius Y, Lagergren P, Lagergren J, Johar A, Hultman CM, Wikman A. Aspects of emotional functioning following oesophageal cancer surgery in a population-based cohort study. Psycho-Oncology 2015;24(1):47-53 PMID: Hellstadius Y, Lagergren J, Zylstra J, Gossage J, Davies A, Hultman M, Lagergren P, Wikman A. Prevalence and predictors of anxiety and depression among oesophageal cancer patients prior to surgery. Diseases of the Esophagus 2016;29(8): PMID: Backemar L, Lagergren P, Johar A, Lagergren J. The impact of co-morbidity on mortality after oesophageal cancer surgery. Br J Surg. 2015;102(9): PMID: Wikman A, Ljung R, Johar A, Hellstadius Y, Lagergren J, Lagergren P. Psychiatric morbidity and survival after surgery for esophageal cancer: a population-based cohort study. J Clin Oncol. 2015;33(5): PMID: Backemar L, Lagergren P, Djärv T, Johar A, Wikman A, Lagergren J. Comorbidities and risk of complications after surgery for esophageal cancer: A nationwide cohort study in Sweden. World J Surg. 2015;39(9): PMID: Rutegård M, Lagergren P, Johar A, Lagergren J. Time shift in early postoperative mortality after oesophagectomy for cancer. Ann Surg Oncol 2015;22(9): PMID: van der Schaaf M, Johar A, Wijnhoven B, Lagergren P, Lagergren J. Extent of lymph node removal during esophageal cancer surgery and survival. JNCI 2015;107(5) PMID: Martin L, Lagergren P. Risk factors for weight loss among patients surviving five years after esophageal cancer surgery. Ann Surg Oncol. 2015;22(2):610-6
5 PMID: Brusselaers N, Mattsson F, Johar A, Wikman A, Lagergren P, Lagergren J, Ljung R. Marital status and survival after oesophageal cancer surgery: A population-based nationwide cohort study in Sweden. BMJ Open 2014;4(6):e PMID: Djärv T, Derogar M, Lagergren P. Influence of co-morbidity on long-term quality of life after oesophagectomy of cancer. Br J Surg 2014;101(5): PMID: van der Schaaf M, Derogar M, Johar A, Rutegård M, Gossage J, Mason R, Lagergren P, Lagergren J. Reoperation after oesophageal cancer surgery in relation to long-term survival: a population-based cohort study. BMJ Open 2014;4(3):e PMID: Derogar M, Sadr-Azodi O, Lagergren P, Lagergren J. Splenic injury during resection for esophageal cancer: Risk factors and consequences. Ann Surg 2015;261(1):111-6 PMID: Brusselaers N, Ljung R, Mattsson F, Johar A, Wikman A, Lagergren P, Lagergren J. Education level and survival after oesophageal cancer surgery: a prospective populationbased cohort study. BMJ Open 2013;3(12) :e PMID: van der Schaaf M, Tilanus H, van Lanschot J, Johar A, Lagergren P, Lagergren J, Wijnhoven B. The influence of preoperative weight loss on postoperative course after esophageal cancer resection. Journal of Thoracic and Cardiovascular Surgery 2014;147(1):490-5 PMID: Wikman A, Johar A, Lagergren P. Presence of symptom clusters in surgically treated esophageal cancer patients implications for survival. Cancer 2014;120(2): PMID: van der Schaaf M, Johar, A, Lagergren P, Rouvelas I, Gossage J, Mason R, Lagergren J. Surgical prevention of reflux after oesophagectomy for cancer. Ann Surg Oncol 2013;20(11): PMID: Djärv T, Wikman A, Johar A, Lagergren P. Poor health-related quality life in the Swedish general population: the association with disease and lifestyle factors. Scand J Public Health 2013;41(7): PMID:
6 49. Lagergren J, Mattsson F, Lagergren P. Clinical implementation of a new antibiotic prophylaxis regimen for percutaneous endoscopic gastrostomy. BMJ Open ;3(5) PMID: Lagergren J, Lagergren P. Recent developments in esophageal adenocarcinoma. CA Cancer J Clin 2013;63(4): PMID: Wikman A, Smedfors G, Lagergren P. Emotional distress a neglected topic among surgically treated oesophageal cancer patients. Acta Oncologica 2013;52(8): PMID: Backemar L, Djärv T, Wikman A, Johar A, Ross P, Lagergren J, Lagergren P. The role of diabetes and other co-morbidities on survival after esophageal cancer surgery in a population-based study. The American Journal of Surgery 2013;206(4): PMID: Löfdahl H, Lu Y, Lagergren P, Lagergren J. Risk factors for oesophageal denocarcinoma after antireflux surgery. Ann Surg 2013;257(4): PMID: Derogar M, Sadr-Azodi O, Johar A, Lagergren P, Lagergren J. Hospital and surgeon volume in relation to survival after esophageal cancer surgery in a population-based study. J Clin Oncol 2013;31(5):551-7 PMID: van der Schaaf M, Rutegård M, Lagergren P. The influence of surgical factors on persisting symptoms 3 years after esophageal cancer surgery - A population-based study in Sweden. Ann Surg Oncol 2013;20(5): PMID: Hellgren EM, Lagergren P, Larsson AC, Schandl AR, Sackey SV. Body image after severe skin and soft tissue infection requiring intensive care relation to anatomic site, gender and psychological outcome. Acta Anaesthesiol. Scand 2013;57(2):220-8 PMID: Lagergren P, Johar A, Lagergren J. Validation of the reflux scale in the EORTC QLQ-OES18. Eur J Cancer 2013;49(5): PMID: Wikman A, Djärv T, Johar A, Lagergren P. Health-related quality of life does not differ between short-term, long-term and very long-term cancer survivors in the Swedish general population. Psychooncology 2013;22(6):
7 PMID: Djärv T, Wikman A, Lagergren P. Number and burden of cardiovascular diseases in relation to health-related quality of life in a cross-sectional population-based cohort study. BMJ Open 2012;2(5) PMID: Martin L, Blomberg J, Lagergren P. Patients' perspectives of living with a percutaneous endoscopic gastrostomy (PEG). BMC Gastroenterol 2012;12(1):126 PMID: Djärv T, Wikman A, Johar A, Nordenstedt H, Lagergren J, Lagergren P. Physical activity, obesity and gastroesophageal reflux disease in the general population. World J Gastroenterol 2012;18(28): PMID: Rutegård M, Charonis K, Lu Y, Lagergren P, Rouvelas I. Population-based oesophageal cancer survival after surgery without neoadjuvant therapy: an update. Surgery 2012;152(5): PMID: Rutegård M, Lagergren P, Rouvelas I, Mason R, Lagergren J. Surgical complications and long-term survival after esophagectomy for cancer in a nationwide Swedish cohort study. Eur J Surg Oncol 2012;38(7): PMID: Derogar M, Orsini N, Sadr-Azodi O, Lagergren P. Influence of major postoperative complications on health-related quality of life among long-term survivors of esophageal cancer surgery. J Clin Oncol 2012;30(14): PMID: Blomberg J, Lagergren J, Martin L, Mattsson F, Lagergren P. Complications after percutaneous endoscopic gastrostomy (PEG) in a prospective study. Scand J Gastroenterol 2012;47(6): PMID: Derogar M, Lagergren P. Health-related quality of life among long-term survivors 5 years after esophageal cancer surgery a prospective population-based study. J Clin Oncol 2012;30(4):413-8 PMID: Djärv T, Lagergren P. Quality of life after oesophagectomy for cancer. Expert Rev Gastroenterol Hepatol 2012;6(1): PMID:
8 68. van der Schaaf M, Derogar M, Lagergren P. Reference values of esophago-gastric symptoms (EORTC QLQ-OG25) in a population-based setting. Eur J Cancer 2012;48(11): PMID: Rutegård M, Lagergren P, Rouvelas I, Lagergren J. Intrathoracic Anastomotic Leakage and Mortality After Esophageal Cancer Resection: A Population-Based Study. Ann Surg Oncol 2012;19(1): PMID: van der Schaaf M, Lagergren J, Lagergren P. Persisting symptoms after intra-thoracic anastomotic leak following oesophagectomy for cancer. Br J Surg 2012;99(1):95-9 PMID: Derogar M, van der Schaaf M, Lagergren P. Reference values for the EORTC QLQ-C30 quality of life questionnaire in a random sample of the Swedish population. Acta Oncologica 2012;51(1):10-6 PMID: Ljung R, Jansson C, Nordenstedt H, Martin L, Lagergren P, Lagergren J. Twelve tips for conducting a postgraduate course on study design and study protocol writing for the medical profession.medical Teacher 2012;34(1):25-9 PMID: Rutegård M, Lagergren P, Nordenstedt H, Lagergren J. Oesophageal adenocarcinoma: The new epidemic in men? Maturitas 2011;69(3):244-8 PMID: Lagergren J, Lagergren P. Clinical review: Oesophageal cancer. BMJ 2010;26;341:c6280 PMID: Löfdahl HE, Lane A, Lu Y, Lagergren P, Harvey RF, Blazeby JM, Lagergren J. Increased population prevalence of reflux and obesity in the United Kingdom compared with Sweden: a potential explanation for the difference in incidence of oesophageal adenocarcinoma. Eur J Gastroenterol Hepatol 2011;23(2): PMID: Djärv T and Lagergren P. Six-month postoperative quality of life predicts long-term survival after esophageal cancer surgery. Eur J Cancer 2011;47(4):530-5 PMID: Blomberg J, Lagergren P, Martin L, Mattsson F, Lagergren J. Albumin and C-reactive protein levels predict short-term mortality after percutaneous endoscopic gastrostomy (PEG) in a prospective cohort study. Gastrointestinal Endoscopy 2011;73(1):29-36
9 PMID: Rutegård M, Nordenstedt H, Lu Y, Lagergren J, Lagergren P. Sex-specific exposure prevalence of established risk factors for oesophageal adenocarcinoma. Br J Cancer 2010;103(5): PMID: Blomberg J, Lagergren P, Martin L, Mattsson F, Lagergren J. Novel approach to antibiotic prophylaxis in percutaneous endoscopic gastrostomy (PEG): randomised controlled trial. BMJ 2010;341:c3115 PMID: Rutegård M, Shore R, Lu Y, Lagergren P, Lindblad M. Sex differences in the incidence of gastrointestinal adenocarcinoma in Sweden Eur J Cancer 2010;46(6): PMID: Djärv T, Metcalfe C, Avery K, Lagergren P, Blazeby JM. The prognostic value of changes in health-related quality of life scores during curative treatment for esophago-gastric cancer. J Clin Oncol 2010;28(10): PMID: Lagergren J, Ye W, Lagergren P, Lu Y. The risk of esophageal adenocarcinoma after antireflux surgery. Gastroenterology 2010;138(4): PMID: Blomberg J, Wenger U, Lagergren J, Arnelo U, Agustsson T, Johnsson E, Toth E, Lagergren P. Antireflux stent versus conventional stent in the palliation of distal esophageal cancer. A randomized multicenter clinical trial. Scand J Gastroenterol 2010;45(2): PMID: Rutegård M, Lagergren P, Hughes R, Blazeby JM. Determinants of global quality of life before and after major cancer surgery: an exploratory study. Qual Life Res 2009;18(9): PMID: Martin L, Lagergren P. Long-term weight change after oesophageal cancer surgery. Br J Surg 2009;96(11): PMID: Djärv T, Blazeby JM, Lagergren P. Predictors of post-operative quality of life after esophagectomy for cancer. J Clin Oncol 2009;27(12): PMID:
10 87. Rutegård M, Lagergren J, Rouvelas I, Lagergren P. Surgeon volume is a poor proxy for skill in esophageal cancer surgery. Ann Surg 2009;249(2): PMID: Rubio CA, Suzuki G, Jaramillo E, Lagergren P, Nesi G. Antralization of the gastric mucosa of the incisura angularis and its gastrin expression. Int J Clin Exp Path 2009;2(1):65-70 PMID: Palmer G, Martling A, Lagergren P, Cedermark B, Holm T. Quality of life after potentially curative treatment for locally advanced rectal cancer. Ann Surg Oncol 2008;15(11): PMID: Martin L, Jia C, Rouvelas I, Lagergren P. Risk factors for malnutrition after oesophageal and cardia cancer surgery. Br J Surg 2008;95(11): PMID: Rutegård M, Lagergren P. No influence of surgical volume on health-related quality of life after oesophageal cancer resection. Ann Surg Oncol 2008;15(9): PMID: Djärv T, Lagergren J, Blazeby JM, Lagergren P. Long-term health-related quality of life following surgery for oesophageal cancer. Br J Surg 2008;95(9): PMID: Rutegård M, Lagergren J, Lindblad M, Rouvelas R, Blazeby JM, Lagergren P. A populationbased study of surgical factors in relation to health-related quality of life after oesophageal cancer resection. Br J Surg 2008;95(5): PMID: Barbour AP, Lagergren P, Hughes R, Alderson D, Barham CP, Blazeby JM. Health-related quality of life outcomes with adenocarcinoma of the gastro-oesophageal junction: a comparison of oesophagectomy and gastrectomy. Br J Surg 2008;95(1):80-4 PMID: Lagergren P, Fayers P, Conroy T, Stein H, Sezer O, Hardwick R, von Cutsem E, Blazeby JM, on behalf of the European Organisation for Research and Treatment of Cancer Gastrointestinal and Quality of Life groups. Clinical and psychometric validation of a questionnaire module, the EORTC QLQ-OG25, to assess health-related quality of life in patients with cancer of the oesophagus, the oesophago-gastric junction and the stomach. Eur J Cancer 2007;43(14): PMID: Lagergren P, Avery KNL, Hughes R, Barham CP, Alderson D, Falk SJ, Blazeby JM. Healthrelated quality of life among patients cured by surgery for esophageal cancer. Cancer 2007;110(3):686-93
11 PMID: Martin L, Lagergren J, Lindblad M, Rouvelas I, Lagergren P. Malnutrition after oesophageal cancer surgery in Sweden. Br J Surg 2007;2;94(12): PMID: Martin L, Lagergren J, Jia C, Lindblad M, Rouvelas I, Viklund P. The influence of needle catheter jejunostomy on weight development after oesophageal cancer surgery in a population-based study. Eur J Surg Oncol 2007;33(6):713-7 PMID: Viklund P, Lagergren J. A care pathway for patients with oesophageal cancer. Eur J Cancer Care 2007;16(6):533-8 PMID: Lagergren J, Viklund P. Is esophageal adenocarcinoma occurring late after antireflux surgery due to persistent reflux? World J Surg 2007;31(3):465-9 PMID: Rouvelas I, Zeng W, Lindblad M, Viklund P, Ye W, Lagergren J. Impact of hospital volume on long-term survival after esophageal cancer surgery. Arch Surg 2007;142(2):113-7 PMID: Rouvelas I, Jia C, Viklund P, Lindblad M, Lagergren J. Surgeon volume and postoperative mortality after oesophagectomy for cancer. Eur J Surg Oncol 2007;33(2):162-8 PMID: Rouvelas I, Zeng W, Lindblad, M, Viklund P, Ye W, Lagergren J. Survival after neoadjuvant treatment compared with surgery alone for resectable esophageal cancer in a population-based study. World J Surg 2006;30(12): PMID: Lagergren J, Jansson C, Viklund P. Chewing gum and risk of adenocarcinoma of the esophagus and cardia. Eur J Cancer 2006;42(14): PMID: Lagergren J, Viklund P, Jansson C. Carbonated soft drinks and esophageal adenocarcinoma: No association in a population-based case-control study. J Natl Cancer Inst 2006;98(16): PMID: Viklund P, Wengström Y, Rouvelas I, Lindblad M, Lagergren J. Quality of life and persisting symptoms after esophageal cancer surgery. Eur J Cancer 2006;42(10):
12 PMID: Viklund P, Lindblad M, Lu M, Ye W, Johansson J, Lagergren J. Risk factors for complications after esophageal cancer resection: A nationwide and prospective population-based population-based study in Sweden. Ann Surg 2006;243(2): PMID: Viklund P, Wengström Y, Lagergren J. Supportive care for patients with esophageal and other upper gastrointestinal cancers: The role of a specialist nurse in the team. Eur J Oncol Nurs 2006;10(5): PMID: Rouvelas I, Zeng W, Lindblad, M, Viklund P, Ye W, Lagergren J. Survival after surgery for esophageal cancer: a population-based study. Lancet Oncol 2005;6(11): PMID: Viklund P, Lindblad M, Lagergren J. The influence of surgery-related factors on quality of life after esophageal or cardia cancer resection. World J Surg 2005;29(7) PMID:
List of publications - Pernilla Lagergren
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