Clinico-pathological Evaluation of Cervical Lymph Node Metastasis of Tongue Squamous Cell Carcinoma Keywords :
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1 Clinico-pathological Evaluation of Cervical Lymph Node Metastasis of Tongue Squamous Cell Carcinoma Yasuhiko Tsuyama, Takashi Nakatsuka, Yoshiyuki Mori, Tsuyoshi Takato (Department of Plastic and Reconstruction Surgery, Saitama Medical School, Moroyama, Iruma-gun, Saitama , Japan, Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, University of Tokyo ) We retrospectively evaluated the relationship between clinico-pathological factors and cervical lymph nodes metastases in 50 patients with primary tongue squamous cell carcinoma, who were treated by curative resection from April 1991 to March Clinically, we evaluated the tumor size according to the TNM classification of UICC(1992). Histopathologically, we evaluated the tumor differentiation, pattern of invasion, stage of invasion and lymphoplasmacytic infiltration. Primary and secondary metastases to the cervical lymph nodes after initial therapy were found in 13 patients (26%) and 6 patients(12%), respectively. As the statistical analysis, the Mann-Whitney test was used to compare the occurrence of primary metastases with the frequency of no metastases, and the occurrence of secondary metastases with the frequency of no metastases. There was a significant correlation between the stage of invasion and the occurrence of cervical lymph nodes metastases(p 0.05). A primary tumor was found associated with cervical lymph nodes metastases in the cases with a total histological malignancy score(total score of pattern of invasion, stage of invasion and lymphoplasmacytic infiltration.) of 8 or more(). Thus, the stage of invasion and histological grading of malignancy are considered to be the most important risk factors of cervical lymph nodes metastases of tongue squamous cell carcinoma. Keywords : tongue, squamous cell carcinoma, cervical lymph node metastasis J Saitama Med School 2002;29: (Received January 8, 2002) 1-5) 1986Anneroth 3) ,8,9)
2 1 :13 :6 : UICC TNM 6) WHO 7) Anneroth 3) Table 1:Point 1~4 AnnerothPoint 34 Point 3 Point 4 Mann-Whitney Fisher s exact probability method 5 1. T Table 2 1 P Table 3 P Table Table 5 1 Table 1. Histologic grading of malignancy regarding tumor-host relationship Point Morphologic Parameter Pattern of Pushing, well delineated Infi ltrating, solid cords, Small groups or cords Marked and wide- Invasion infi ltrating borders bands and/or strands of infi ltrating cells spread cellular dissoci- (n 15). ation in small groups of cells(n 15) and/or in single cells Stage of Carcinoma in situ and/ Distinct invasion, but Invasion below lamina Extensive and deep Invasion or questionable invasion involving lamina pro- propria adjacent to invasion replacing Pria only muscles, salivary gland most of the stromal tissues and periosteum tissue and infi ltrating jaw bone Lympho- Marked Moderate Slight None plasmacytic infi ltration Histologic malignancy grading system of oral squamous cell carcinoma proposed by Anneroth et al. (1987)
3 5. (Table 6) 1 P 0.61 P Table 7 Point 8 P 0.05 Point 9 T1 T2 Table 4. Relationship between pattern of invasion and the Pattern of Primary Secondary No Total invasion metastasis metastasis metastasis Point Point Point Point Table 2. Relationship between T * factors and the frequency of cervical lymph nodes metastases Table 5. Relationship between stage of invasion and the T category Primary Secondary No Total metastasis metastasis metastasis Stage of Primary Secondary No Total invasion metastasis metastasis metastasis T T T T Point Point Point Point P 0.98 T * category of TNM classifi cation according to UICC, Table 3. Relationship between dif ferentiation and the Table 6. Relationship between lymphoplasmacytic infi ltration and the Lymphoplasmacytic Primary Secondary No Total Degree of Primary Secondary No Total Differentiationmetastasis metastasis metastasis Grade Grade Grade infi ltration metastasis metastasis metastasis Point Point Point Point P 0.10 P 0.61 P 0.18
4 Table 7. Relationship between total histological malignancy score and the total histological malignancy score 10,11) 12,13) T1 T2 T1 T2 Point 9, 14) 2,5,15) Point4 4,5,8) 9) 4~5 mm 5,8) ) 1 1-3,8,10,11,20-23) 21) Point 8 23)
5 Point 8 1) Jacobsson PA, Eneroth CM, Killander D, Moberger G, Martensson B. Histological classification and grading of malignancy in the cancer of the larynx. Acta Radiol Ther Phys Biol 1973;12:1-7. 2) Yamamoto E, Miyakawa A, Kohama G. Mode of invasion and lymph node metastasis in squamous cell carcinoma of the oral cavity. Head Neck Surg 1984;6: ) Anneroth G, Batsakis J, Luna M. Review of the literature and a recommended system of malignancy in oral squamous cell carcinoma. Scand J Dent Res 1987;95: ) Brown B, Barnes L, Mazariegos J, Taylor F, Johnson J, Wagner RL. Prognostic factors in mobile tongue and floor of mouth carcinoma. Cancer 1989; 64: ) Morton RP, Ferguson CM, Lambie NK, Whitlock RML. Tumor thickness in early tongue cancer. Arch Otolaryngol Head Neck Surg 1994;120: ) Hermanek P, Sobin LH, editors. TNM Classification of Malignant Tumors. 4th ed. 2nd ver. International Union Against Cancer. Berlin: Springer; ) WHO. Application of the International Classification of Diseases to Dentistry and Stomatology. 2nd ed. Geneva:WHO; ) Fukano H, Matsuura H. Depth of invasion. Potentiality for predictive factor of cervical lymphnode metastasis in tongue carcinoma. Head Neck Surg 1995; 120: ), ; 33: ) Teichgraeber JF. The incidence of occult metastases for cancer of the oral tongue and floor of the mouth: Treatment rationale. Head Neck Surg 1984; 7: ),. N ;17: ) ; 25: ) Tulenco J, Hoffmeister FS. Cancer of the tongue. Comments on surgical treatment. Am J Surg 1966; 112: ),,,,, ;43: ) Anneroth G, Hansen LS, Silverman SJr. Malignancy grading in oral squamous cell carcinoma.. Squamous cell carcinoma of the tongue and floor of mouth: histologic grading in the clinical evaluation. J Oral Pathol 1986;15: ) Crissman JD, Liu MY, Gluckman JL, Cumming G. Prognostic value histopathologic parameters in squamous cell carcinoma of the oropharynx. Cancer 1984;54: ). 1955;43: ) MacCarthy, WC. Factors which influence longevity in cancer. Ann Surg 1922;76: ) Powel LD. The relationship of cellular differentiation, fibrosis, hyalization, and lymphocytic infiltration to post operative longevity of patients with squamouse-cell epithelioma of the skin and lip. J Cancer Res 1923;7: ) ;21: ),,,,, ;36: ) Willen R, Nathanson A. Squamous cell carcinoma of the gingiva. Histological classification and grading of malignancy. Acta Otolaryngol 1975;79: ) ;39: The Medical Society of Saitama Medical School
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