Date & Time Apr. 20 (Thu.), 11:10-12:10 Venue Halla Hall Moderators Prof. Sung-Bae Kim (ASAN Medical Center, Korea)

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2 Plenary Lecture 1: Past and Future Treatment of HER2-Positive Breast Cancer Date & Time Apr. 20 (Thu.), 11:10-12:10 Venue Halla Hall Prof. Sung-Bae Kim (ASAN Medical Center, Korea) Prof. Martine Piccart (Institut Jules Bordet, Belgium) Satellite Symposium 1: The Role of Faslodex in Advanced Breast Cancer Management Pursuing Long Term Treatment Strategy Date & Time Apr. 20 (Thu.), 12:10-13:10 Venue Halla Hall Prof. Dong-young Noh (Seoul National Univ. Hospital, Korea) Prof. Peter Schmid (Barts Cancer Institute, Queen Mary Univ. of London, United Kingdom) Plenary Lecture 2: What is the Current Concept of Molecular Portraits of Human Breast Tumors Date & Time Apr. 20 (Thu.), 13:30-14:30 Venue Halla Hall Prof. Min-Hyuk Lee (Soonchunhyang Univ. Hospital Seoul, Korea) Prof. Charles M. Perou (Univ. of North Carolina at Chapel Hill, U.S.A.) Symposium 1: Breast Cancer Prevention and Screening Date & Time Apr. 20 (Thu.), 14:40-15:50 Venue Halla Hall Prof. Eun Sook Lee (National Cancer Center, Korea) Prof. Steven A Narod (Dalla Lana School of Public Health, Univ. of Toronto, Canada) Breast Cancer Screening: Harm or Good? Prof.Steven A Narod (Dalla Lana School of Public Health, Univ. of Toronto, Canada) Assessment of Breast Cancer Risk with Genetic Polymorphisms Dr. Antonis Antoniou (Univ. of Cambridge, United Kingdom) Germline Testing for Hereditary Cancer with Multigene Panel Prof. Po-Han Lin (National Taiwan Univ. Hospital, Taiwan)

3 Panel Discussion 1: Elderly Breast Cancer Date & Time Apr. 20 (Thu.), 14:40-15:50 Venue Lotus Hall Prof. Janice Tsang (Hong Kong Breast Oncology Group (HKBOG), Hong Kong) Comprehensive Geriatric Assessment for Elderly Patients Prof. Jee Hyun Kim (Seoul National Univ. Bundang Hospital, Korea) Local Therapy Prof. Seho Park (Yonsei Univ. College of Medicine, Korea) Systemic Therapy Prof. Janice Tsang (Hong Kong Breast Oncology Group (HKBOG), Hong Kong) Oral Presentation 1: Date & Time Apr. 20 (Thu.), 14:40-15:50 Venue Weolla Room Prof. Jeong Soo Kim (The Catholic Univ. of Korea, Uijeongbu St. Mary's Hospital, Korea) Prof. Woo-Chan Park (The Catholic Univ. of Korea, Yeouido St. Mary's Hospital, Korea) TBD Education Session 1: New Issues in Cancer Research and Treatment Date & Time Apr. 20 (Thu.), 16:00-17:10 Venue Halla Hall Prof. Woong-Yang Park (Samsung Medical Center, Korea) Prof. Naoto Ueno (The Univ. of Texas, MD Anderson Cancer Center, U.S.A.) Clinical Utility of Liquid Biopsy in Cancer Prof. Byung-Joo Chae (Seoul St.Mary's Hospital, Korea) Targeted Panel Sequencing Prof. Woong-Yang Park (Samsung Medical Center, Korea) New Issues in Identifying Cancer Driver Prof. Tae-Min Kim (College of Medicine, The Catholic Univ. of Korea, Korea)

4 Panel Discussion 2: Special Issues in Stage IV Breast Cancer Date & Time Apr. 20 (Thu.), 16:00-17:10 Venue Lotus Hall Prof. Jin Zhang (Tianjin Medical Univ. Cancer Center, China) Surgery for Stage IV Breast Cancer: No Benefit at All? Prof. Jin Zhang (Tianjin Medical Univ. Cancer Center, China) New Therapeutic Strategy for CNS Metastases in Breast Cancer Prof. Hee Kyung Ahn (Gachon Univ. Gil Medical Center, Korea) How Long Should We Treat Patients with Metastatic Breast Cancer? Is Cure Possible? Prof. Louis Chow (Macau Univ. of Science and Technology, Hong Kong) Satellite Symposium 2: Dose Intensity and the Importance of Febrile Neutropenia Prevention Date & Time Apr. 21 (Fri.), 07:30-08:10 Venue Halla Hall TBD Prof. Yeon Hee Park (Samsung Medical Center, Korea) Plenary Lecture 3: Has Axillary Clearance Become Obsolete? Date & Time Apr. 21 (Fri.), 08:30-09:30 Venue Halla Hall Prof. Soo-Jung Lee (Yeungnam Medical Center, Korea) Prof. Emiel Rutgers (Netherlands Cancer Institute, Netherlands)

5 Symposium 2: Immuno-Oncology - Where We Are? Date & Time Apr. 21 (Fri.), 09:40-10:50 Venue Halla Hall Prof. Kyong Hwa Park (Korea Univ. Anam Hospital, Korea) Prof. Mary L. Disis (Univ. of Washington, U.S.A.) Immune Check-Point Blockade for Breast Cancer Prof. Peter Schmid (Barts Cancer Institute, Queen Mary Univ. of London, United Kingdom) Immune Approaches to the Treatment of Breast Cancer, Around the Corner? Dr. Yasir Nagarwala (Merck & Co., Inc., U.S.A.) Immune Monitoring for Immuno-Oncology Clinical Trials Prof. Mary L. Disis (Univ. of Washington, U.S.A.) Invited Oral Presentation: Date & Time Apr. 21 (Fri.), 09:40-10:50 Venue Lotus Hall Prof. Sang Seol Jung (Bundang CHA Hospital, Korea) Prof. Yoon Sim Yap (National Cancer Centre Singapore, Singapore) Subgroup Analysis of Asian Population Among PALOMA-2 Trials Prof. In Hae Park (National Cancer Center, Korea) Breast MRI Monitoring for Young Breast Cancer Patients after Breast Conservation Therapy: A Multicenter Prospective Study Prof. Woo Kyung Moon (Seoul National Univ. Hospital, Korea) Premenopausal Patient With Hormone Responsive, HER2 Negative, Lymph Node Positive Breast Cancer Prof. Hee-Jeong Kim (Asan Medical Center, Korea) First-Line Ribociclib + Letrozole In Postmenopausal Asian Women With Hormone Receptor-Positive (Hr+), Her2-Negative (Her2-) Advanced Breast Cancer (Abc): A Subgroup Analysis Of Monaleesa-2 Prof. Yoon Sim Yap (National Cancer Centre Singapore, Singapore

6 Symposium 3: Young Age Session Date & Time Apr. 21 (Fri.), 11:00-12:10 Venue Halla Hall Prof. Jung Sil Ro (National Cancer Center, Korea) Prof. Shiji Ohno (Cancer Institute Hospital, Japan) Fertility Preservation Dr. Elizabeth Ginsburg (The Brigham and Women's Hospital, U.S.A.) Chemotherapy- Endocrine Therapy Sequence in Premenopausal Patients Prof. Yeon Hee Park (Samsung Medical Center, Korea) Long-Term Toxicity of Endocrine Therapy Prof. Shinji Ohno (Cancer Institute Hospital, Japan) Education Session 2: Mutational Landscape and Its Implications for Treatment of Breast Cancer Date & Time Apr. 21 (Fri.), 11:00-12:10 Venue Lotus Hall Prof. Kyung Hae Jung (ASAN Medical Center, Korea) Prof. Charles M. Perou (Univ. of North Carolina at Chapel Hill, U.S.A.) Overcoming Heterogeneity: Single Cell Sequencing of Breast Cancer Prof. Wonshik Han (Seoul National Univ. Hospital, Korea) Practical Implications of Next Generation Sequencing in Breast Cancer: Promises and Challenges Prof. Naoto Ueno (The Univ. of Texas, MD Anderson Cancer Center, U.S.A.) Molecular Heterogeneity of Triple-Negative Breast Cancer Prof. Charles M. Perou (Univ. of North Carolina at Chapel Hill, U.S.A.) Satellite Symposium 3: Recent Insight into Clinic for HER2+ mbc Patients Date & Time Apr. 21 (Fri.), 12:10-13:10 Venue Halla Hall Prof. Chanheun Park (Kangbuk Samsung Hospital, Korea) Prof. Tae-Yong Kim (Seoul National Univ. Hospital, Korea)

7 Plenary Lecture 4: The Evolving Role of Immune Regulation in Breast Cancer Date & Time Apr. 21 (Fri.), 13:30-14:30 Venue Halla Hall Prof. Young-Hyuck Im (Samsung Medical Center, Korea) Prof. Mary L. Disis (Univ. of Washington, U.S.A.) Nursing Session: Management of Metastatic, Recurrent and Intractable Breast Cancer Date & Time Apr. 21 (Fri.), 13:30-15:10 Venue Weolla Room Prof. Mi Young Kang (Cheil General Hospital, Korea) Survivorship Issues of the Metastatic, Recurrent and Intractable Breast Cancer Dr. Yaelim Lee (Yeouido St. Mary s Hospital, Korea) Nursing Care in Bone Metastasis Ms. Hyejin Cho (Ewha Womans Univ. Mokdong Hospital, Korea) Nursing Care in Visceral Metastasis Ms. Seung Hee Seon (Korea Univ. Guro Hospital, Korea) Specialist Nursing Roles for the Patient with Metastatic, Recurrent and Intractable Breast Cancer Ms. Su jin Lee (Dankook Univ. Hospital, Korea) Complementary and Alternative Therapies Prof. Eun-Young Jun (DaeJeon Univ., Korea) ABRCA & HBOC: ABRCA & HBOC Session Date & Time Apr. 21 (Fri.), 14:30-15:50 Venue Lotus Hall Prof. Seigo Nakamura (Showa Univ. School of Medicine, Korea) Breast Cancer Genetics- How is it Changing Our Practice Prof. Ava Kwong (The Univ. of Hong Kong, Hong Kong) Panel Testing and SNP Testing (Polygenic Risk Score) in Asian Women Prof. Soo-Hwang Teo (Cancer Research Malaysia, Malaysia) Breast Cancer Genetics and Cancer Policy Prof. Steven A Narod (Dalla Lana School of Public Health, Univ. of Toronto, Canada) Genetic Susceptibility to Breast Cancer: Roles of High- Moderate- and Modest-Penetrance Alleles Prof. David Goldgar (Univ. of Utah School of Medicine, U.S.A.)

8 Symposium 4: Challenges in the Implementation of Biosimilar: New Frontiers in Oncology Date & Time Apr. 21 (Fri.), 14:40-15:50 Venue Halla Hall Prof. Joon Jeong (Gangnam Severance Hospital, Korea) Prof. Xavier Pivot (Univ. Hospital of Besancon, France) Clinical Considerations for the Development of Biosimilars in Oncology Dr. Chul Kim (Samsung Bioepis Co., Ltd., Korea) G-CSF (PEG-GCSF) Biosimilar: Clinical Application and Experience Prof. Fumikata Hara (National Hospital Organization, Japan) Trastuzumab Biosimilar Prof. Xavier Pivot (Univ. Hospital of Besancon, France) Panel Discussion 3: Minimizing Local Therapy Date & Time Apr. 21 (Fri.), 16:00-17:10 Venue Halla Hall Prof. Yong-Sheng Wang (Shandong Cancer Hospital Affiliated to Shandong Univ., China) Do We Need Excision in ccr Patients after Neoadjuvant Chemotherapy Prof. Han-Byoel Lee (Seoul National Univ. Hospital, Korea) Can We Omit Sentinel Lymph Node Biopsy in Some Patients Prof. Jeong Eon Lee (Samsung Medical Center, Korea) Extent and Role of Radiation Therapy in pcr Patients Prof. Yong Bae Kim (Yonsei Cancer Center, Korea) Panel Discussion 4: Role of Imaging in the Era of ALND Omitting of N1 Breast Cancer Date & Time Apr. 21 (Fri.), 16:00-17:10 Venue Lotus Hall Prof. Emiel Rutgers (Netherlands Cancer Institute, Netherlands) USG or FNA for Predicting Node Positive in Breast Cancer Prof. Chiun-Sheng Huang (National Taiwan Univ. Hospital, National Taiwan Univ. College of Medicine, Taiwan) Accuracy of PET for Lymph Node Evaluation Prof. Emiel Rutgers (Netherlands Cancer Institute, Netherlands) Nomogram to Predict 3 or More Lymph Node Metastasis Prof. Wonshik Han (Seoul National Univ. Hospital, Korea)

9 Satellite Symposium 4: Prognostic Diagnosis for HR+/HER2- Early Breast Cancer Patient Based on the Algorithm through the Gene Expression Signature Date & Time Apr. 21 (Fri.), 17:30-18:20 Venue Halla Hall Prof. Byung-Joo Song (The Catholic Univ. of Korea, Seoul St. Mary's Hospital, Korea) Prof. Young Kee Shin (Seoul National Univ., Korea) Satellite Symposium 5: Expanding Horizons-CDK4/6 Inhibitors in HR+ Breast Cancer Date & Time Apr. 22 (Sat.), 07:30-08:10 Venue Halla Hall Prof. Nam-Sun Paik (Ewha Womans Univ. Cancer Center for Women, Korea) Prof. Sung-Bae Kim (ASAN Medical Center, Korea) Plenary Lecture 5: Haute Couture Tailoring of Radiation Therapy in Breast Cancer Date & Time Apr. 22 (Sat.), 08:30-09:30 Venue Halla Hall Prof. Chang-Ok Suh (Yonsei Cancer Center, Yonsei Univ. Health System, Korea) Prof. Philip Poortmans (Institut Curie Paris, Netherlands) Symposium 5: To Treat or Not Date & Time Apr. 22 (Sat.), 09:40-10:50 Venue Halla Hall Prof. Philip Poortmans (Institut Curie Paris, Netherlands) Prof. Doo Ho Choi (Samsung Medical Center, Korea) Post-BCS WBRT: Invasive Carcinoma & DCIS Prof. Su Ssan Kim (Univ. of Ulsan College of Medicine, Asan Medical Center, Korea) PMRT in pn1 Prof. Hae Jin Park (Hanyang Univ. Hospital, Korea) IMN: Balancing Risks and Benefits Prof. Philip Poortmans (Institut Curie Paris, Netherlands)

10 Survivorship Session: Advances in Breast Cancer Survivor's Care Date & Time Apr. 22 (Sat.), 09:40-10:50 Venue Lotus Hall Prof. Jung Han Yoon (Chonnam National Univ. Hwasun Hospital, Korea) Prof. Ava Kwong (The Univ. of Hong Kong, Hong Kong) E-health Innovation in Breast Cancer Prof. Miyako Takahashi (National Cancer Center, Japan) Life after Breast Cancer in Australia Prof. Hyukjai Shin (Myongji Hospital, Medical School of Seonam Univ., Korea) Health Status and Healthcare Utilization of Breast Cancer Survivors Dr. Jihyoun Lee (Soonchunhyang Univ. Hospital, Korea) Oral Presentation 2: Date & Time Apr. 22 (Sat.), 09:40-10:50 Venue Weolla Room Prof. Young Up Cho (Inha Univ. Hospital, Korea) Prof. Ho Yong Park (Kyungpook National Univ. Hospital, Korea) TBD Symposium 6: Personalized Therapy Date & Time Apr. 22 (Sat.), 10:50-12:00 Venue Halla Hall Prof. Joohyuk Sohn (Yonsei Cancer Center, Korea) Prof. Martine Piccart (Institut Jules Bordet, Belgium) How to Interpret the Omics Big Data and Apply to the Clinical Practice Dr. Yu Shyr (Vanderbilt Univ. Medical Center, U.S.A.) Personalized Adjuvant Therapy Based on Clinical Trials in Breast Cancer Prof. Martine Piccart (Institut Jules Bordet, Belgium) Where are We Now, to the Precision Medicine Prof. Masakazu Toi (Kyoto Univ. Hospital, Japan)

11 Education Session 3: Cell Cycle, CDKs and Breast Cancer: A Changing Paradigm Date & Time Apr. 22 (Sat.), 10:50-12:00 Venue Lotus Hall Prof. Seock-Ah Im (Seoul National Univ., Korea) Dr. Melanie Cruz (Philippine Breast Cancer Society, Philippines) Cell Cycle Regulation and Targeting CDK 4/6 for Treatment of Breast Cancer Prof. Seock-Ah Im (Seoul National Univ., Korea) CDK 4/6 Inhibitors for the Treatment of Breast Cancer: A Review of Clinical Data Prof. Jin-Hee Ahn (ASAN Medical Center, Korea) Ongoing Clinical Trials Combining CDK 4/6 Inhibitors and Related Biomarkers Dr. Soohyeon Lee (Pfizer Oncology, Korea) Oral Presentation 3: Date & Time Apr. 22 (Sat.), 10:50-12:00 Venue Weolla Room Prof. Tae Hyun Kim (Inje Univ. Busan Paik Hospital, Korea) Prof. Lee Su Kim (Hallym Univ. Sacred Heart Hospital, Korea) TBD

Global Breast Cancer Conference 2019 (GBCC 2019) with Annual Meeting of Korean Breast Cancer Society (KBCS)

It is our great honor to invite you to the Global Breast Cancer Conference 2019 (GBCC 2019), which will be held at Songdo ConvensiA in Incheon, Korea, from April 25 (Thu) to 27 (Sat), 2019. Hosted by the