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2 September 13-14, 2013 ICLA 2013 IMEABLE September 13 (Fri), 2013 ime / Venue Convention Hall A Convention Hall B 08:15~10:15 Symposium I Basic Research Committee Workshop 10:15~10:45 Coffee Break 10:45~11:00 Opening Remarks Plenary Lecture 1 11:00~11:40 Philip Barter (University of New South Wales, Australia) 11:40~12:00 Break 12:00~13:45 Luncheon Symposium. 13:45~15:45 Food and Nutrition Committee Workshop 15:45~16:15 Coffee Break Presentation for Projects Funded by KSLA 16:15~18:15 Symposium II Symposium III September 14 (Sat), 2013 ime / Venue Convention Hall A Convention Hall B 08:15~10:30 Symposium IV Symposium VII 10:30~11:00 Coffee Break 11:00~11:40 Plenary Lecture 2 Peter Libby (Brigham and Women's Hospital, USA) 11:40~12:00 Break 12:00~13:30 Luncheon Symposium 13:30~15:00 Symposium V Organizations-KSLA Joint Symposium 15:00~15:30 Coffee Break 15:30~17:45 Symposium VI 17:45~ Closing he 46 th Fall Conference of the Korean Society of Lipidology & Atherosclerosis

3 ICLA 2013 September 13-14, 2013 CONENS Plenary Lecture I Room A, B - Friday, September 13, 11:00-11:40 Chair : Chee Jeong Kim Inflammation in Atherosclerosis: Role of High Density Lipoproteins Philip Barter (University of New South Wales, Australia) 2 Plenary Lecture II Room A, B - Saturday, September 14, 11:00-11:40 Chair : Young-Bae Park Inflammation in Atherosclerosis; From Pathophysiology to herapeutic Implications Peter Libby (Brigham and Women's Hospital, USA) 4 Symposium 1. Bioactive Lipids as Signaling Molecules Room A - Friday, September 13, 08:15-10:15 Chairs : Jeong Euy Park, Youngmi Kim S1-1. Regulation of Sphingolipids Biosynthesis by Endoplasmic Reticulum Stress ae-sik Park (Gachon University, Korea) 8 S1-2. Lysophospholipid Signaling in the Central Nervous System Ji Woong Choi (Gachon University, Korea) 10 S1-3. N-acyl Chain Length of Sphingolipid Affects Insulin Resistance Via Lipid Raft Modulation Joo-Won Park (Ewha Womans University, Korea) 12 S1-4. Bioactive Phospholipid Profiling and Its Applications to Biomedical Researches Hyun Ju Yoo (University of Ulsan, Korea) 14 Symposium 2. Perspectives of Nutrition and Exercise herapies for Reducing Obesity Related Cardiometabolic Risk Room A - Friday, September 13, 16:15-18:15 Chairs : Jung Han Yoon Park, Hak Chul Jang S2-1. Serum Adiponectin, Prediabetes, and Cardiovascular Risk in Korean Men and Women Sun Ha Jee (Yonsei University, Korea) 16 S2-2. ime-course Activation of the Adipokine Dysregulation and Induction of Fibrosis in Visceral Adipose Depots During Diet-Induced Obesity in Animal Model Myung-Sook Choi (Kyungpook National University, Korea) 18 S2-3. Nutrigenetic Approach to the Study for Glucose Intolerance and Diabetes Mellitus Jong Ho Lee (Yonsei University, Korea) 20 S2-4. Aging, Exercise, and Cardioprotection Hyo-Bum Kwak (Inha University, Korea) 22 he 2 nd International Congress on Lipid Metabolism & Atherosclerosis

4 September 13-14, 2013 ICLA 2013 CONENS Symposium 3. Controversies in Non-Invasive Imaging Room B - Friday, September 13, 16:15-18:15 Chairs : Jeong Euy Park, Hyo-Soo Kim S3-1. Coronary C Angiography Can Replace Invasive Angiography: Pros Young-Hak Kim (University of Ulsan, Korea) 24 S3-2. Coronary C Angiography Can Replace Invasive Angiography: Contras Young Joon Hong (Chonnam National University, Korea) 26 S3-3. Cardiac Magnetic Resonance Imaging Can Replace Nuclear Imaging: Pros Sang Il Choi (Seoul National University, Korea) 28 S3-4. Cardiac Magnetic Resonance Imaging Can Replace Nuclear Imaging: Contras Won Jun Kang (Yonsei University, Korea) 30 Q&A Panels : Byung Jin Kim, Seonghoon Choi, Soon Jun Hong, Joon Hyung Doh Symposium 4. he Unfilled Secret Shell, Atherosclerosis: Beyond Related Classic Biomarkers Room A - Saturday, September 14, 08:15-10:30 Chairs : Joong-Yeol Park, Goo aeg Oh S4-1. Exploring Cardiovascular Effects of Vaspin: Focused on Its Anti-Atherogenic Mechanism Chang Hee Jung (University of Ulsan, Korea) 32 S4-2. Osteocalcin and Atherosclerosis Ippei Kanazawa (Shimane University, Japan) 34 S4-3. Glycated Albumin: Not Only Glycemic Index But Also Biomarker of Atherosclerosis in Diabetes Kwang Joon Kim (Yonsei University, Korea) 36 S4-4. Role of Adipocytokines in Cardiovascular Disease Noriyuki Ouchi (Nagoya University, Japan) 38 Symposium 5. New Insights into Atherosclerosis Room A - Saturday, September 14, 13:30-15:00 Chairs : In Kyu Lee, Myeong-Ki Hong S5-1. Role of Micro RNAs in the Pathogenesis of Atherosclerosis Hae-Young Lee (Seoul National University, Korea) 40 S5-2. Molecular Imaging of Vascular Calcification in Atherosclerosis Eung-Hyuck Cho (Yonsei University, Korea) 42 S5-3. Searching for Novel Variants in Familial Hypercholesterolemia: a Whole Exome Sequencing Study Sang-Hak Lee (Yonsei University, Korea) 44 S5-4. Influence of Shear Stress in the Pathogenesis of Atherosclerosis - Mechanotransduction in Vascular Physiology and Atherogenesis Kihwan Kwon (Ewha Womans University, Korea) 46 he 46 th Fall Conference of the Korean Society of Lipidology & Atherosclerosis

5 ICLA 2013 September 13-14, 2013 CONENS Symposium 6. Atherosclerosis: Deep Dive from Element to Practice Room A - Saturday, September 14, 15:30-17:45 Chairs : Kyong Soo Park, Sang-Wook Kim S6-1. Coronary Calcium: Blade for Heart? Hyun-Jai Cho (Seoul National University, Korea) 50 S6-2. Risk Score Model Assessing the Coronary Artery Disease in Asymptomatic ype 2 Diabetes Gyung-Min Park (he Catholic University, Korea) 52 S6-3. PAD on CAD Patients: Bystander or Determiner Jong-Young Lee (University of Ulsan, Korea) 54 S6-4. Confirm Registry: Dose Coronary C Angiography Make No Doubt in CAD Patients? Hyuk-Jae Chang (Yonsei University, Korea) 56 Q&A Panels : Seung-Whan Lee, Sang-Ho Jo, Sang Il Choi Symposium 7. Diagnosis and reatment of Atherosclerosis Using High-Density Lipoprotein Room B - Saturday, September 14, 08:15-10:30 Chairs : Hong Kyu Lee, Ki Hoon Han S7-1. A Peptide Mimetic of Apolipoprotein A-I hat Contains 2-naphthylalanineresidues Enhances Cholesterol Efflux from and Sequesters Oxidized LDL in Macrophage Cells Jaehoon Yu (Seoul National University, Korea) 58 S7-2. Antiatherosclerotic Effects of Reconstituted HDL and Apolipoprotein A1 Mimetic Peptide and Its Potential Clinical Application Jeong Euy Park (Sungkyunkwan University, Korea) 60 S7-3. Dysfunctional HDL in Cardiovascular Disease and Metabolic Syndrome Kyung-Hyun Cho (Yeungnam University, Korea) 62 Q&A Panels : Jae Ryong Kim, Chi Dae Kim, Jin Han Organizations-KSLA Joint Symposium: How to Make Synergy Between Public, Industrial, and Academic Partners Room B - Saturday, September 14, 13:30-15:00 Chair : Donghoon Choi JS-1. Korea Biobank Project Soo-Youn Lee (Korea National Institution of Health, Korea) 66 JS-2. Collaboration Between Sponsor and Center in Drug Development of Atherosclerosis Hyunhee Na (Sanofi, Korea) 68 JS-3. Arteriosclerosis-related Medical Imaging echnology Development and Industrialization Strategy Hyuk-Jae Chang (Yonsei University, Korea) 72 Q&A Panels : Geum-Sook Hwang, Jeongho Kim, Min Soo Park he 2 nd International Congress on Lipid Metabolism & Atherosclerosis

6 September 13-14, 2013 ICLA 2013 CONENS Presentation for Projects Funded by KSLA Room B - Friday, September 13, 13:45-15:45 Chairs : Jin Han, Soo Lim P-1. Usefulness of Cardiac Biomarkers in the Evaluation of Prognosis and Cardiac Involvement in Patients with Acute Aortic Syndrome Kye Hun Kim (Chonnam National University, Korea) 76 P-2. etrahydrobiopterin Supplementation Effect on Proteomic and Functional Changes of Cardiac Mitochondria in OLEF Hyoung Kyu Kim (Inje University, Korea) 78 P-3. Rosuvastatin for the Prevention of Deep Vein hrombosis in Patients Undergoing otal Knee Replacement Arthroplasty-SOP DV Study: Aprospective Randomized Open-label Controlled rial Sang-Ho Jo (Hallym University, Korea) 80 Luncheon Symposium I Room A - Friday, September 13, 12:00-13:45 Chair : Myung Ho Jeong LS-1. Balancing Efficacy and Safety in Dyslipidemia Management Sin Gon Kim (Korea University, Korea) 84 LS-2. Stream of RAS Based herapy Byung Jin Kim (Sungkyunkwan University, Korea) 86 Luncheon Symposium II Room A - Saturday, September 14, 12:00-13:30 Chair : Joong-Yeol Park LS-1. Diabetes and Dyslipidemia Management Dae Jung Kim (Ajou University, Korea) 88 LS-2. Atherosclerosis and Dyslipidemia Management Sang-Hyun Kim (Seoul National University, Korea) 90 he 46 th Fall Conference of the Korean Society of Lipidology & Atherosclerosis

7 ICLA 2013 September 13-14, 2013 CONENS POSER EXHIBIION Lipid Metabolism 95 PE1 PE2 PE3 PE4 PE5 he Effect of N-acyl Chain Length of Sphingolipids on Chemical Induced Liver Damage Joo-Won Park 1 *, Woo-Jae Park 2, Anthony H. Futerman 3 Department of Biochemistry, School of Medicine, Ewha Womans University 1, Department of Biochemistry, School of Medicine, Gachon University, Korea 2, Department of Biological Chemistry, Weizmann Institute of Science, Rehovot 76100, Israel 3 he Effect of Sphingolipids on Oxysterol-Binding Protein Gene Expression Joo-Won Park* Department of Biochemistry, School of Medicine, Ewha Womans University, Korea Serum Resistin is Not Associated with the Response to Lipid-Lowering herapy in Non-Diabetic Patients with Coronary Artery Disease Sahmin Lee*, Yoon-Ki Kim, Han-Mo Yang, Hyun-Jai Cho, Byung-Hee Oh, Young-Bae Park, Hyo-Soo Kim Department of Internal Medicine, Seoul National University College of Medicine, Korea Association between Serum Fibroblast Growth Factor 19 Level, Lipid Metabolism, and Coronary Artery Stenosis Eunshil Hong*, Ah Rheum Khang, Eu Jeong Ku, Eun Roh, Ye Ahn Kim, Kyoung Min Kim, Jae Hoon Moon, Soo Lim, Hak Chul Jang, Sung Hee Choi Internal Medicine, Seoul National University Bundang Hospital, Korea he Relationship Between Serum Lipids and Depression KeumJi Jung 1 *, Yejin Mok 1, Dong-Koog Son 3, Eun-Jeong Han 3, Sun Ha Jee 2 Graduate School of Public Health, Yonsei University 1, Institute for Health Promotion, Graduate School of Public Health, Yonsei University 2, National Health Insurance Service, Korea 3 Coronary Artery & Other Vascular Diseases 97 PE6 PE7 PE8 he 2 nd PGC-1alpha Regulates Endothelial Cell Barrier Function by Suppressing Angiopoietin-2 Expression Sang Eun Lee*, Young Chan Kim, Eun-Byeul Hong, Inju Hwang, Hyun-Jai Cho, Hyo-Soo Kim, Young-Bae Park National Research Laboratory for Stem Cell Niche, Seoul National University College of Medicine, Cardiovascular Center & Department of Internal Medicine, Seoul National University Hospital, Innovative Research Institute for Cell herapy, Seoul National University Hospital, Korea Gallic Acid Attenuates Vascular Smooth Muscle Cell Calcification via Down-Regulation of BMP2 Signaling Pathway Hae Jin Kee*, Myung Ho Jeong Heart Research Center of Chonnam National University Hospital nominated by Korea Ministry of Health and Welfare, Korea Frequency and Evolution of hin-capped Fibroatheromas in Left Main Coronary Artery as Assessed by Serial Virtual Histology Intravascular Ultrasound Analysis Sang Wook Kim 1 *, Wang Soo Lee 1, Gary S. Mintz 2, Neil J. Weissman 3, Nagendra Boopathy Senguttuvan 1, Jee Eun Kwon 1, Hyangkyoung Kim 1, Jae Seung Seo 1, Ju Won Seok 1, Eun Young Kim 1, Sung Hyup Hyun 1, Joon Hwa Hong 1, Chee Jeong Kim 1, Dai Yun Cho 1, ae Ho Kim 1 Chung-Ang University Hospital, Korea 1, Cardiovascular Research Foundation, NY, USA 2, Washington Hospital Center, DC, USA 3 International Congress on Lipid Metabolism & Atherosclerosis

8 September 13-14, 2013 ICLA 2013 CONENS PE9 PE10 PE11 PE12 Prognostic Value of Ankle-brachial Index in Patients Undergoing Drug-eluting Stent Implantation Hack-Lyoung Kim 1 *, Jae-Bin Seo 1, Woo-Young Chung 1, Zoo-Hee Jo 1, Myung-A Kim 1, Hyo-Soo Kim 2, Young-Bae Park 2 Cardiovascular Center, Seoul National University Boramae Medical Center 1, Cardiovascular Center, Seoul National University Hospital, Korea 2 High Level of Copeptin in S Elevation Acute Myocardial Infarction Patients is Associated with In-Hospital Mortality and Plaque Rupture Jee Eun Kwon*, Sang-Wook Kim, Mi Kyung Lee, Wang-Soo Lee, Joon Hwa Hong, Sung Hyup Hyun, Sharath Kumar, Kyung Sook Park, Kwang Je Lee, ae Ho Kim, Dai Yun Cho, Chee Jeong Kim Chung-Ang University Hospital, Korea Association between Brachial-ankle Pulse Wave Velocity and Coronary Artery Disease Evaluated by Coronary Computed omography Angiography Hack-Lyoung Kim 1 *, Kwang Nam Jin 2, Jae-Bin Seo 1, Yong Ho Choi 2, Woo-Young Chung 1, Sang-Hyun Kim 1, Myung-A Kim 1, Hyo-Soo Kim 3, Young-Bae Park 3, Joo-Hee Zo 1 Division of Cardiology, Department of Internal Medicine, Seoul National University Boramae Medical Center, Seoul National University College of Medicine 1, Department of Radiology, Seoul National University Boramae Medical Center, Seoul National University College of Medicine 2, Division of Cardiology, Department of Internal Medicine, Seoul National University Hospital, Seoul National University College of Medicine, Korea 3 Independent Predictors of Clinical Outcomes in Patients with Normal Coronary Angiography Hyun-Jin Kim 1 *, Hack-Lyoung Kim 1, Jae-Bin Seo 1, Woo-Young Chung 1, Myung-A Kim 1, Sang-Hyun Kim 1, Hyo-Soo Kim 2, Young-Bae Park 2, Joo-Hee Zo 1 Division of Cardiology, Department of Internal Medicine, Seoul National University College of Medicine, Seoul National University Boramae Medical Center 1, Division of Cardiology, Department of Internal Medicine, Seoul National University College of Medicine, Seoul National University Hospital, Korea 2 Cardiometabolic Risk Factors and Biomarkers in Atherosclerosis 101 PE13 PE14 PE15 Identification of a Resistin Receptor hat Mediates Inflammatory Actions in Humans Sahmin Lee 1 *, Hyun-Chae Lee 2, Yoo-Wook Kwon 2, Youngjin Cho 1, Sang Eun Lee 1, Junho Chung 3, Ky-Youb Nam 4, Han-Mo Yang 1, Ju-Young Kim 2, Hyun-Jai Cho 1, Byung-Hee Oh 1, Young-Bae Park 1, Mitchell A. Lazar 5, Hyo-Soo Kim 1 Department of Internal Medicine, Seoul National University College of Medicine 1, National Research Laboratory for Cardiovascular Stem Cell, Clinical Research Institute, Seoul National University Hospital 2, Department of Biochemistry and Molecular Biology, Seoul National University College of Medicine 3, Bioinformatics & Molecular Design Research Center, Yonsei Engineering Research Complex, Yonsei University, Korea 4, Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, and Institute for Diabetes, Obesity, and Metabolism, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA 5 One-Year Clinical Outcomes in Patients with Metabolic Syndrome and Acute Myocardial Infarction Mi-Seon Ji*, Myung Ho Jeong Chonnam National University Hospital, Korea Combinatorial Analysis of Advanced Atherosclerotic Lesions Based on Label-free Multimodal Nonlinear Optical Imaging and Mass Spectroscopy Eun-Soo Lee 1 *, Joo Hyun Park 2, Hyun Kyong Shon 1, ae Geol Lee 1, Sang Won Lee 1, Se-Hwa Kim 1 Nanobio Fusion Research Center, Korea Research Institute of Standards and Science 1, Department of Nano and Bio Surface Science, University of Science and echnology, Korea 2 he 46 th Fall Conference of the Korean Society of Lipidology & Atherosclerosis

9 ICLA 2013 September 13-14, 2013 CONENS Management of Atherosclerosis, Hypertension, and Dyslipidemia 102 PE16 Serum Lipid Profiling of Hypertriglyceridemia Based on Ultra-performance Liquid Chromatography/ Q-OF Mass Spectrometry Ju Yeon Park*, Geum-Sook Hwang Integrated Metabolomics Research Group, Korea Basic Science Institute, Korea Others 103 PE17 PE18 PE19 Diabetes Dysfunctions Angiogenesis of Bone Marrow Stem Cells; Implication of Oxytocin for Functional Restoration Yong Sook Kim*, Wan Seok Kang, Moon Hwa Hong, Hye Jin Kang Heart Research Center, Chonnam National University Hospital, Korea Association of Adiponectin and All-Cause, Cardiovascular Mortality in Elderly Korean Adults Eu Jeong Ku 1 *, Soo Lim 1, Eun Sil Hong 1, Ah Reum Khang 1, Hak Chul Jang 1, Kyong Soo Park 2, Sung Hee Choi 1, Sung Hee Choi 1 Division of Endocrinology and Metabolism Department of Internal Medicine Seoul National University Bundang Hospital 1, Department of Internal Medicine Seoul National University College of Medicine, Korea 2 Incremental Prognostic Value of Brachial-ankle Pulse Wave Velocity to Myocardial Perfusion Imaging in Patients with Suspected Coronary Artery Disease Hee-Sun Lee 1 *, Hack-Lyoung Kim 1, Hong-Mi Choi 1, So-Won Oh 2, Jae-Bin Seo 1, Woo-young Chung 1, Sang-Hyun Kim 1, Myung-A Kim 1, Hyo-Soo Kim 3, Young-Bae Park 3, Joo-Hee Zo 1 Cardiovascular Center, Seoul National University Boramae Medical Center 1, Department of Nuclear Medicine, National University Boramae Medical Center 2, Cardiovascular Center, Seoul National University Hospital, Korea 3 he 2 nd International Congress on Lipid Metabolism & Atherosclerosis

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