A total of 30,115 new cases of HPV-associated cancers were reported in 1999 and 43,371 in 2015.

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1 A total of 30,115 new cases of HPV-associated cancers were reported in 1999 and 43,371 in Oropharyngeal squamous cell carcinoma is now the most common HPV-associated cancer. During cervical carcinoma incidence rates decreased 1.6% per year, and oropharyngeal SCC incidence rates increased 2.7% per year among men and 0.8% per year among women. Ongoing surveillance for HPV-associated cancers using high-quality population-based registries is critical to monitor cancer rates and trends Division of Cancer Prevention and Control Reliable. Trusted. Scientific.

2 Declines specific to vaccine types Vaccine type CIN2+ Other CIN2+ Applied HPV type-specific proportions to population-based incidence data Estimated proportion and numbers of vaccine-type CIN2+ cases have declined Estimated numbers of other CIN2+ cases approximately constant CIN2+, cervical intraepithelial neoplasia, grade 2 or worse or adenocarcinoma in situ McClung et al. Cancer Epidemiology, Biomarkers and Prevention, 2019

3 Supporting Change: The Role of Partnerships and Coalitions Working with national provider and quality improvement organizations HEDIS 2018 reflects current ACIP schedule Convening national partners through the National HPV Vaccination Roundtable Sharing communication resources, best practices, and other tools and materials Collaborating with cancer partners in national and state-level activities Comprehensive Cancer Control National Partnership NCI-designated cancer centers State coalitions and roundtables Engaging integrated healthcare delivery systems 45 Division of Cancer Prevention and Control Reliable. Trusted. Scientific.

4 Strategies to increase HPV vaccination coverage, United States Support state and local immunization programs Strengthen provider commitment Mobilize partners and stakeholders Improve and utilize systems Increase public awareness 46 Division of Cancer Prevention and Control Reliable. Trusted. Scientific.

5 Cervical Cancer is Still a Problem in the United States Age-Adjusted Rate per 100, Trends in Cervical Cancer Mortality, No woman deserves to die of cervical cancer Year Deaths National Cancer Institute, Surveillance, Epidemiology, and End Results program: seer.cancer.gov/statfacts/html/cervix.html CDC, National Center for Health Statistics

6 Cervical Cancer is Still a Problem in the United States Age-Adjusted Rate per 100, Trends in Cervical Cancer Mortality, No woman deserves to die of cervical cancer. We can do better Year Deaths National Cancer Institute, Surveillance, Epidemiology, and End Results program: seer.cancer.gov/statfacts/html/cervix.html CDC, National Center for Health Statistics

7 Cervical Cancer Disparities in the United States ØHigher rates of cervical cancer in: Black and Hispanic women Women living in nonmetropolitan areas Women with lower socioeconomic status Women who have never been screening or not screened in past 5 years AAPC: Average annual percent change NS: Non-significant Henley SJ, Anderson RN, Thomas, CC, et al. MMWR Surveill Summ 2017; Jul 7;66(14):1-13. ):1-13 Age-adjusted Death Rate per 100, Trends in Cervical Cancer in Nonmetropolitan and Metropolitan Counties by Year of Death United States, Year Nonmetropolitan AAPC: -0.5% (NS) Metropolitan AAPC: 0.7% 49 Division of Cancer Prevention and Control Reliable. Trusted. Scientific.

8 How does public health attack these problems?

9 Who Are Our Partners? 95% include representatives from academic & medical institutions 85% include representatives from business & industry 94% include members of professional associations 72% include government partners 100% include representatives from public health programs 76% include policy makers 95% include representatives from community-based organizations 51 Division of Cancer Prevention and Control Reliable. Trusted. Scientific.

10 Comprehensive Cancer Control National Partnership 52 Division of Cancer Prevention and Control Reliable. Trusted. Scientific.

11 National Academies of Science Engineering and Medicine Consensus Study on A National Strategy Comprehensive Cancer Control 53 Division of Cancer Prevention and Control Reliable. Trusted. Scientific. 53

12 Educational Tools for Cancer Patients Linda Avatar TINA Avatar Cancer Survivor Lifestyle Modules Avatar 54 Division of Cancer Prevention and Control Reliable. Trusted. Scientific.

13 Linda Avatar 55 Division of Cancer Prevention and Control Reliable. Trusted. Scientific.

14 56 Division of Cancer Prevention and Control Reliable. Trusted. Scientific.

15 The best way to predict your future is to create it Abraham Lincoln 57 Division of Cancer Prevention and Control Reliable. Trusted. Scientific.

16

17 59 Division of Cancer Prevention and Control Reliable. Trusted. Scientific.

18 Thank you! Go to the official federal source of cancer prevention information: Division of Cancer Prevention and Control Reliable. Trusted. Scientific. The findings and conclusions in this report are those of the authors and do not necessarily represent the official position of the Centers for Disease Control and Prevention.

19 61 Division of Cancer Prevention and Control Reliable. Trusted. Scientific.

20 RELIABLE TRUSTED SCIENTIFIC DCPC 62

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