Curriculum Vitae. Education: 2004 Doctor of philosophy (Biological and medical sciences)
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1 Curriculum Vitae Ms. Chantarawan Saengkhae, Ph.D. Assistant Professor, Faculty of Allied Health Sciences, University, Chonburi, Tel and Fax: , Education: 2004 Doctor of philosophy (Biological and medical sciences) Faculty of Medicine, University of Paris 13, France 1992 Master of Science (Physiology) Faculty of Medicine, Chulalongkorn University, Thailand 1986 Bachelor degree of Science Faculty of Nursing, Mahidol University, (Nursing and Midwifery) Thailand Current Teaching Responsibilities: Undergraduate: 2004-present: 2004-present: Graduate: Lectures in undergraduate course physiology to medical and paramedical students: special topics on the physiology of the nervous and gastrointestinal system Lectures in undergraduate course pathophysiology to traditional Thai medical students: special topics on the pathophysiology of the neuro and gastrointestinal system present: Lectures in graduate course System bioengineering to Engineering students: special topics on the physiology of the nervous system present: Lectures in graduate course pathophysiology to nursing students: special topics on the pathophysiology of the cancer, neuro and gastrointestinal system Funding: Years Funding Agency Title 2005 Faculty of 2006 Faculty of 2007 Faculty of Effects of crude leaf extract of Nelumbo nucifera Gaertn. on isolated aorta derived from hypertensive and normotensive rats Antioxidative effects of crude leaf extract of Nelumbo nucifera Gaertn. on free radical initiated hemolysis of erythrocytes and oxidizability of plasma in hypertensive and normotensive rats. Antiproliferation and Apoptosis of the Crude Extract of Andrographis paniculata Nees, on rat glioma cells
2 2008 National 2009 Faculty of 2010 National 2010 National 2011 Office of the higher education commission 2012 Office of the higher education commission 2013 Faculty of Allied Health Sciences, University 2014 National 2015 National 2017 National (ASK) In Vitro Strategies for the discovery of new anticancer compounds from seaweeds and/or seagrasses in the east coast of the gulf Antiproliferative activities and apoptosis of extracts from Sargassum binderi Sonder on human cervical cancer cells (HeLa) Antiproliferative activities and induction of apoptosis by the extracts of Sargassum oligocystum Montagne on cancer cells Antiproliferative activities of pure compounds from Diospyros filipendula, and Diospyros cauliflora Anti-cancer activities and molecular mechanisms of bioactive metabolites from actinobacteria in suborder Micromonosporineae isolated from marine Apoptosis induction of human cancer cells by Streptomyces strain CH54-4 and SS15-1 isolated from mangrove sediments Anti-cancer and apoptosis-inducing activities of partial purification from Streptomyces indiaensis isolated from coastal soil at the east coast of the Gulf Apoptosis induction of human cancer cells by beach morning glory (Ipomoea pes-caprae) with different extraction methods Anti-oxidant, anti-inflammatory and doxorubicinsensitizing activities by beach morning glory (Ipomoea pes-caprae) using different extraction methods Structured-based design and development of marine active substances, Aeroplysinin-1, as potential anticancer agents Publication: Loetchutinat C, Saengkhae C, Marbeuf-Gueye C & Garnier-Suillerot A. New insights into the P-glycoprotein-mediated effluxes of rhodamines. Eur J Biochem. 2003; 270:
3 Saengkhae C, Loetchutinat C & Garnier-Suillerot A. Kinetic analysis of rhodamines efflux mediated by the multidrug resistance protein (MRP1). Biophys J. 2003; 85: Saengkhae C, Loetchutinat C & Garnier-Suillerot A. Kinetic analysis of fluorescein and dihydrofluorescein effluxes in tumour cells expressing the multidrug resistance protein, MRP1. Biochem Pharmacol. 2003; 65: Salerno M, Loechariyakul P, Saengkhae C & Garnier-Suillerot A. Relation between the ability of some compounds to modulate the MRP1-mediated efflux of glutathione and to inhibit the MRPl-mediated efflux of daunorubicin. Biochem Pharmacol. 2004; 68: Saengkhae C, Salerno M, Ades D, Siove A, Le Moyec, Migonney V & Garnier- Suillerot A. Ability of carbazole salts, inhibitors of Alzheimer -amyloid fibril formation, to cross cellular membranes. Eur J Pharmacol. 2007; 559: Saengkhae C, Arunnopparat W & Sungkhajorn P. Antioxidative activity of the leaf of Nelumbo nucifera Gaertn. on oxidative stress-induced erythrocyte hemolysis in hypertensive and normotensive rats. Thai Journal of Physiological Sciences. 2007; 20(2): Saengkhae C, Arunnopparat W & Sungkhajorn P. Oxidative hemolysis and osmotic fragility of erythrocytes in renovascular hypertensive and normotensive rats. Chula Med J. 2007; 51(11): Saengkhae C & Archariyapibal. Cytotoxicity and apoptosis effect of crude extract of Andrographis paniculata Nees. (APE) on rat glioma cells (ASK). Sci J. 2008; 13(2): Saengkhae C & Meewassanasuk K. Antiproliferation and apoptosis of the crude of Andrograhhis paniculate Nees on human oropharyngeal cancer cells (KB) in vitro. Thai Journal of Physiological Sciences ; 21(2): Saengkhae C, Noiraksar T, Jongaramruong J & Palee P. Antiproliferation and induction of apoptosis by extract of Turbinaria conoides (J. Agardh) Kützing on human cervical cancer cell line. Chula Med J. 2010; 54(1): Saengkhae C, Noiraksar T, Jongaramruong J & Piekpia J. Antiproliferative and Apoptosis-Inducing Activities of Extracts from Sargassum binderi Sonder on Human Cervical Cancer Cells. Sci J. 2010; 15(1): Saengkhae C, Pumpunphol J & Srivibool, R. Extraction of Micromonospora aurantiaca isolated from coastal marine sediment enhances doxorubicin induced apoptosis in KB cells. J Physiol Biomed Sci. 2013; 26(2): Saengkhae C, Premsuriya Y, Srivibool R and Praiboon J. Sensitization of human carcinoma of nasopharynx cells to doxorubicin and induction of apoptosis by Sargassum baccularia lipophilic fraction. Walailak J Sci & Tech. 2015; 12(6): Saengkhae C, Srivibool R, Watanadilok R and Enomoto K. Partially purified pigment extract from Streptomyces A 16-1 induces apoptosis of human carcinoma of nasopharynx Cell (KB cells) via the mitochondrial and caspase-3 pathway. Walailak J Sci & Tech. 2017; 14(1): Proceeding:
4 Saengkhae C, Katsawang K, Tatiyarut M & Trongtorsak P. Effects of crude leaf extract of Nelumbo nucifera Gaert. on isolated aorta derived from normotensive and hypertensive rats. Poster Presentation in the 35th Conference of Thai Physiological Society. May 3-5, Chieng Mai Thailand. Sangkajon P, Arunnoparat W & Saengkhae C. Protective effect of the leaf of Nelumbo nucifera Gaert. on free-radical-induced erythrocyte hemolysis in hypertensive and normotensive rats. Poster Presentation in the 36th Conference of Thai Physiological Society. April 25-27, Ayudhaya Thailand. Meewasassanasuk K & Saengkhae C. Anti-proliferative effects of crude extracts from Andrographis paniculata Nees. on human oropharyngeal epidermoid carcinoma (KB) cells. Poster Presentation in the 37th Conference of Thai Physiological Society. May 7-9, Garden sea view resort, Chonburi, Thailand. Saengkhae C. Antiproliferation and apoptosis of crude extract of Andrographis paniculata Nees. on human breast adenocarcinoma cells (MCF-7) in Vitro. Oral presentation in the 6th Conference of Thai Medicinal Plant. Sep 2-4, Impact Muangtongtanee, Nontaburi, Thailand. Saengkhae C & Naengchomnong W. Anti-proliferative activities of pure compounds from Diospyros filipendula and Diospyros cauliflora. Poster Presentation in the 40th Conference of Thai Physiological Society. May 2-4, Pullman Raja Orchid Hotel, Kon-Kheni, Thailand. Saengkhae C, Vuncheelong J, Noiraksar T & Jongaramruong J. Antiproliferative activities and induction of apoptosis by the extracts of Sargassum oligocystum Montagne on HeLa cancer cells. Oral presentation in University National Conference. July 6-7, Saengkhae C. Pumpunphol J & Srivibool R. Sensitization of KB Cells to Doxorubicin by MAG 9-19 Extracted from Micromonospora in Marine Sediments. Poster Presentation in the 40th Conference of Thai Physiological Society. May 2-4, Faculty of medicine, Siriraj hospital, Bangkok, Thailand. Saengkhae C, Premsuriya Y, Srivibool R & Praiboon J. Sensitization of human carcinoma of nasopharynx cells to doxorubicin and induction of apoptosis by crude fucoxanthin extracted from Sargassum baccularia. Poster Presentation in the 6th Conference of Algae and Planton. May 28-30, The Empress Hotel Chiang Mai, Thailand. Saengkhae C, Kowbuanarn K, Jandong J & Srivibool R. Anti-proliferative and apoptosis-inducing activities of partial purification from Streptomyces indiaensis against human nasopharyngeal epidermoid carcinoma cells (KB cells). Poster Presentation in 43 th Annual Scientific Meeting of The Physiological Society of Thailand "SYSTEMS BIOLOGY- WEAVING THE WEB OF LIFE" April Garden Cliff Resort & Spa. Pattaya, Thailand. Saengkhae C, Uawongyart N & Osiri S. Cytotoxic and antioxidant potential of Ipomoea Pes Caprae with different extracts methods. Poster Presentation in 8 th Federation of the Asian and Oceanian Physiological Societies (FAOPS Congress)
5 Translational Physiology: Imagination, Inspiration and Innovation November 22-25, 2015 At Centara Grand & Bangkok Convention Centre at Central World. Bangkok, Thailand. Saengkhae C, Uawongyart N, Osiri S & Tangwattanachuleeporn M. Antiinflammatory potential of Ipomoea pes-caprae (L.) R.Br. with different extraction methods. Poster Presentation in 44 th Annual Scientific Meeting of The Physiological Society Integrative Physiology: From Mitochondria to Man December 22-24, The Empress International Convention Center, Chiengmai, Thailand
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