GASTROINTESTINAL METASTASES FROM LOBULAR BREAST CANCER

Transcription

1 42. 1,. 1,. 2, , 2, GASTROINTESTINAL METASTASES FROM LOBULAR BREAST CANCER V. Gerova 1, L. Tankova 1, A. Mihova 2, I. Drandarsk 2 and H. Kadian 1 1 Clinic of Gastroenterology, University Hospital Tsaritsa Yoanna ISUL Sofia 2 Laboratory of Pathomorphology, Military Medical Academy Sofia : ( ) -. -,. ( ) ,, 5 (pt1b, N1, M0) - ( ). -, -, ( ) - -. :,, : -,,,,,. 8, 1527,.: , vanger@hotmail.com Summary: Breast cancer (BC) is the most common malignancy in the women. Metastatic BC typically involves lungs, liver and bones. Gastrointestinal (GI) metastases are rare and usually occur in patients with invasive lobular BC. The upper GI tract is more frequently involved. We report a case of a 56-year-old woman with liver, gastric and rectal metastases five years after radical left mastectomy with axillary node dissection because of invasive lobular BC ((pt1b, N1, M0), followed by adjuvant radiotherapy and hormonal therapy (tamoxifen). Ultrasonography, endoscopy and ultrasonographic endoscopy because of abdominal discomfort, tenesmus and rectal bleeding demonstrated liver, gastric and rectal metastases with histological and immunohistological patterns of metastatic lobular BC. The patient died 10 months after diagnosing of GI metastases. The case is of interest with a feature of liver and GI metastases in double sites (stomach and rectum) and illustrates the need of special attention to search for GI metastatic disease in patients with invasive BC who present with nonspecific GI symptoms. Key words: breast carcinoma, metastases, gastrointestinal tract Address for correspondence: Vanya Gerova, MD, PhD, Clinic of G stroenterology, University Hospital Tsaritsa Yoanna ISUL, 8 Byalo more str., Bg-1527, Sofia, tel.: , vanger@hotmail.com

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