Travel: Chikungunya, Zika,.. New worries
|
|
- Lorraine Byrd
- 6 years ago
- Views:
Transcription
1 Travel: Chikungunya, Zika,.. New worries McGill Family Physician Refresher Course Dec 6, 2016 Makeda Semret, MD FRCP(C) Infectious Diseases/ Medical Microbiology
2 Disclosures Funding from PHAC/CIHR/GSK/Novartis for influenza surveillance in Montreal In-kind research support from biomerieux for work on Hospital-Associated Infections in Africa (Ethiopia) No speaking or consultancy fees from industry 2
3 Objectives Know when to suspect an arboviral (arthropod-borne virus) infection in travelers and common clinical scenarios Know what laboratory tests to send and the limitations of these tests Know current guidelines for management of Zika exposure, and available resources 3
4 37 year old female, previously healthy Presents to your clinic with fever, myalgias, malaise, lethargy x 3 days. Returned 12 days ago from one week stay in Haiti No localising signs and symptoms Temp C, BP 120/80, HR 108, RR 20 Looks unwell but not toxic Cardiac, Resp, Abdo, MSK: unremarkable WBC 3.0 (lymphs 1.0); Plt 95; Hb 122 4
5 Your working diagnosis? Further investigations? Further management? 5
6 Fever from the tropics leading life-threatening illness The No. 1 life threatening infection for travelers about 30,000 European and N. American travelers infected annually,?150 die 4% mortality (P.f.); 20% in severe cases Am J Trop Med Hyg 2013;88:
7 Malaria in travellers leading life-threatening illness Am J Trop Med Hyg 2013;88:
8 First Key Message In a febrile patient from the tropics, always rule out malaria (and bacterial sepsis) - TODAY. You cannot (in Canada) make a firm diagnosis of an arboviral infection on the first visit. 8
9 Second Key Message: Geography! Ann Intern Med. 2013;158:
10 Third message: things change!! Chikungunya Dec 2013 Chikungunya Dec
11 Things change.. 11
12 Why do (did) these diseases spread? Some of these viruses can be transmitted human to human but not a preferred route, and therefore relatively low risk E.g., sexual transmission of Zika virus Spread of these diseases follow the distribution of the vector (the mosquitoe) Distribution influenced by climactic changes and vector adaptation 12
13 Vectors for Transmission for Dengue, Chikungunya, Zika: Aedes sp Day feeders; once infected, mosquitoes stay infected for life (30-45d) Also responsible for Yellow Fever transmission! Aedes aegyptii Aedes albopictus 13
14 Adaptation of the vector Slide courtesy of Dr M. Libman
15 Societal changes: uncontrolled urbanization Slide courtesy of M. Libman
16 World Wide Distribution of Aedes aegypti elife 2015;4:e08347, accessed Nov 19,
17 The viruses Dengue and Zika are flaviviruses Same family as Yellow Fever, West Nile, Japanese encephalitis They can cross-react in serological tests (! vaccinees) Chikungunya is an alphavirus Same family as Mayaro, O'nyong'nyong, and others associated with encephalitis, arthritis syndromes No serological cross-reactions with dengue or zika 17
18 They initially present in much the same way Short Incubation (3-10d most frequently) Fever, myalgias, headache, malaise +/- rash: last 3-7 days Low WBC and Plts How do you differentiate? 18
19 First, worry about Dengue Frequent cause of fever in travelers from SE Asia and Central America/Caribbean. Can lead to severe illness with possible hemorrhagic fever (rare) --- you can't tell who will progress to severe disease until a good 72h after defervescence Monitor closely for warning signs 19
20 Warning signs Abdominal pain or tenderness Persistent vomiting Clinical fluid accumulation (ascites, effusions) Mucosal bleeding Lethargy/restlessness Liver enlargement > 2cm Hematocrit increase, rapid decrease in PLT Start at defervescence (D5-6) and last 48-72h 20
21 Manage (while waiting for diagnosis) Supportive treat symptoms but avoid NSAIDS if dengue still a possibility potential for bleeding Testing: serology (requesting serology for all 3 makes sense, but in practice dengue +/- chik first) Follow-up (at least by telephone) to ensure no progression If dengue: no long-term sequelae; also no life long immunity (at least 4 different serotypes) - so discuss risk of re-infection 21
22 Chikungunya "to walk bent up in makonde - nothing to do with chickens! Initial presentation like dengue More arthralgias/arthritis but often these occur later (after defervescence) - can lead to significant morbidity, other complications rare Immunity after infection is probably lifelong 22
23 Back to our patient Improves with symptomatic management A few days later tells you she has been trying to get pregnant She has no joint symptoms You are still waiting for her serology results.. 23
24 24
25 Zika beware what you think you know 25
26 Zika beware what you think you know accessed Oct
27 Zika Infection typical clinical disease Incubation usually 2 to 14 days Resolves spontaneously Approx 80% asymptomatic
28 Zika Infection vertical transmission Vertical transmission Est. Risk of microcephaly from Zika infection in T1 = 1-13% First time we face infectious epidemic teratogen since rubella Neither pre-2007 Asian nor African lineages directly implicated with congenital Zika syndrome or neurologic illness (unnoticed vs different bio?)
29 Zika Infection sexual transmission Human cases Confirmed in 9 nonendemic countries and 3 endemic countries High endemic F:M ratio suggests it s common Vaginal, oral, anal sex Mostly M F even without symptoms RNA persistance Fluid Typical Record Blood* 7-14d * 81d* Urine 14 Saliva? (no known transm) Semen? 188d (culture -) Vaginal secretions? 14 Breats milk (only 1 case of live virus, no transm reported)?? 69d (culture +)
30 Precautions/prevention for zika? Since many infections are asymptomatic : travellers to endemic area and who want to eventually conceive should have protected sex (or abstain) for: 6 months for Men; 2 months for Women (CDC and PHAC) 6 months for both (WHO) Barrier precautions for duration of pregnancy if already pregnant ttps:// 30
31 Who to test? Any pregnant woman who has been in an area with Zika: If symptomatic and within 14 days of symptoms send both PCR of blood+urine AND serology If no symptoms (or > 14 days since symptoms): send serology (PRNT will be done if IgM positive) If >12 weeks since trip or symptoms, do not send (false negatives), but recommend to follow ultrasound Ultrasound within 4 weeks of exposure and q 4 weeks until lab results 31
32 Important details on testing Testing will be rejected by provincial lab unless details of travel (dates, place) and symptoms (with dates) are provided legibly on the requisition. You can test Men if specify "wishing to conceive, pregnant partner, adding epidemiological info (area, dates of travel) 32
33 Zika in Canada As of 30 Sept 2016: 328 travel associated cases 2 sexually transmitted cases 2 maternal fetal transmissions 14 pregnant women Outcome available for 2 only one with Zika associated abnormalities, one without 33
34 Counselling for our patient What would you advise her pending results? What would you advise if she had been asymptomatic? What if her Zika serology comes back negative? And if her partner had traveled with her? And if he had not traveled with her? 34
35 Many unanswered questions True risk of vertical transmission? By trimester? % of vertical transmission with clinical consequences? Importance of sexual transmission, and max duration of infectivity? Neurological complication rate for adults? Clinical differences between lineages? 35
36 Take home messages Don t forget malaria commonest life threatening cause of fever. Arboviruses are more frequent causes of fever in travelers from the Americas and SE Asia. Most are self limited Dengue can sometimes be life threatening Chikungunya can lead to chronic morbidity Zika is an issue for pregnancy 36
37 Take home messages (cont d) The results of tests for all these diseases take several weeks to become available; also issue of cross reactivity, so clinical and epidemiologic context is important PREVENTION: No vaccines for any! Day-biting mosquito-avoidance (DEET/ICARDIDIN; light-coloured clothing, wind, air conditioning) 37
38 Questions? J.D. MacLean Centre for Tropical Diseases 38
Public Health Image Library. CDC/ Cynthia Goldsmith. Image #
Zika Virus Fredrick M. Abrahamian, D.O., FACEP, FIDSA Clinical Professor of Medicine UCLA School of Medicine Director of Education Department of Emergency Medicine Olive View-UCLA Medical Center Sylmar,
More informationObjectives. Dengue, Chikungunya and Zika Virus Infection: Answers to Common Questions. Case 1. Dengue Introduction 10/15/2018
Dengue, Chikungunya and Zika Virus Infection: Answers to Common Questions Wayne Ghesquiere MD FRCPC Infectious Diseases Consultant Clinical Assistant Prof, UBC Victoria, BC Objectives Discuss common Arbovirus
More informationWhat s Lurking out there??????
What s Lurking out there?????? Dave Warshauer, PhD, D(ABMM) Deputy Director, Communicable Diseases Wisconsin State Laboratory of Hygiene david.warshauer@slh.wisc.edu WISCONSIN STATE LABORATORY OF HYGIENE
More informationZIKA VIRUS. John J. Russell MD May 27, 2016
John J. Russell MD May 27, 2016 HISTORY Discovered 1947 Zika Forest of Uganda in rhesus monkeys, thus the name Found in humans in Africa in 1952 Not considered a public health threat until outbreak in
More informationZika Virus Guidance for Medical Providers. Denise Smith, PHN, MPA Director of Disease Control Kern County Public Health Services Department
Zika Virus Guidance for Medical Providers Denise Smith, PHN, MPA Director of Disease Control Kern County Public Health Services Department Kern Perinatal Symposium March 3, 2017 CME DISCLOSURE The Planners,
More informationZika Virus Update for Emergency Care Providers
Zika Virus Update for Emergency Care Providers What is this Zika Virus? Jeff Doerr Epidemiologist Southeastern Idaho Public Health Zika Virus Single stranded RNA virus Genus Flavivirus, Family Flaviviridae
More informationZika Virus: The Olympics and Beyond
Zika Virus: The Olympics and Beyond Alice Pong, MD Pediatric Infectious Diseases Rady Children s Hospital-San Diego University of California, San Diego Disclosures I have no disclosures to report 1 Objectives
More informationAn Introduction to Dengue, Zika and Chikungunya Viruses
An Introduction to Dengue, Zika and Chikungunya Viruses Natalie Marzec, MD, MPH Zoonoses Epidemiologist 2017 Global Health and Disasters Course Objectives Arbovirus Overview Public Health Activities Clinical
More informationZika virus infection Interim clinical guidance for Primary Care
Zika virus infection Interim clinical guidance for Primary Care Zika virus infection is a notifiable disease in Ireland under the Infectious Diseases (Amendment) Regulations 2016 (S.I.. 276 of 2016). All
More informationZika: Deet, There It Is. Anna Powell, MD Reproductive Infectious Disease Fellow THEGOS
Zika: Deet, There It Is Anna Powell, MD Reproductive Infectious Disease Fellow THEGOS Disclosure I have no financial disclosures or conflicts of interest Lessons from Rubella At peak of rubella epidemic
More informationZika Virus. ZIKA VIRUS & PREGNANCY Stephen Champlin, M.D. FLAVIVIRIDAE VIRUS SPECTRUM. Virus family Flaviviridae
ZIKA VIRUS & PREGNANCY Stephen Champlin, M.D. Zika Virus Virus family Flaviviridae Positive sense, single-stranded RNA virus FLAVIVIRIDAE VIRUS SPECTRUM Arbovirus - spread by arthropods to mammals Flaviviridae
More informationThis memo is intended to provide information to NC clinicians and laboratories regarding diagnosis, management and reporting of Zika virus infection.
May 18, 2016 (replaces version dated March 31, 2016) To: From: North Carolina Health Care Providers and Laboratories Megan Davies, MD, State Epidemiologist Scott Zimmerman, DrPH, MPH, HCLD (ABB), State
More informationModule Three About Zika Virus: What is Known and Not Known
Module Three About Zika Virus: What is Known and Not Known HOUSEKEEPING For educational and quality improvement purposes, this TeleECHO Clinic will be recorded By participating in this clinic, you are
More informationA RELOOK AT ZIKA VIRAL INFECTION AND ITS LATEST OUTBREAK IN INDIA
24 th December 2018 A RELOOK AT ZIKA VIRAL INFECTION AND ITS LATEST OUTBREAK IN INDIA BACKGROUND Zika virus infection, which erupted on a large scale in 2015-2016, has infected more than 1.5 million people.
More informationZika Virus. Centers for Disease Control and Prevention
Centers for Disease Control and Prevention Zika Virus Ingrid Rabe Medical Epidemiologist Arboviral Diseases Branch Centers for Disease Control and Prevention February 1, 2016 Zika Virus Single stranded
More informationZika Virus. Maternal & Fetal Effects. John P. Elliott, MD Medical Director, Valley Perinatal Services Phoenix, Arizona
Zika Virus Maternal & Fetal Effects John P. Elliott, MD Medical Director, Valley Perinatal Services Phoenix, Arizona Objective of Presentation Sneeka Peeka at Zika Disclosure I have nothing to disclose
More information2017 SCAAP Summer Conference. Lilian Peake, MD, MPH
2017 SCAAP Summer Conference Lilian Peake, MD, MPH 1. Mosquito-borne Diseases 2. Challenges to Preventing and Controlling Mosquito-borne Diseases 3. Effects of Zika Virus on Child Health None Accelerating
More informationZika Virus What Every Woman Needs to Know
Zika Virus What Every Woman Needs to Know Carrie L. Byington, MD The Jean and Thomas McMullin Professor and Dean of Medicine Senior Vice President Health Science Center Vice Chancellor for Health Services
More informationZIKA: is South Africa at risk? Lucille Blumberg National Institute for Communicable Diseases South Africa
ZIKA: is South Africa at risk? Lucille Blumberg National Institute for Communicable Diseases South Africa 18 th April 1947; Rhesus macaque (no 766) with fever Filtrable transmissable agent The absence
More informationZika Virus Update. Partner Webinar 05/12/2016
Zika Virus Update Partner Webinar 05/12/2016 Today s presenters Patricia Quinlisk, MD, MPH, Medical Director /State Epidemiologist Ann Garvey, DVM, MPH, MA, State Public Health Veterinarian/ Deputy State
More informationZIKA VIRUS OUTBREAK. JANET B. EDDY M.D. KU-WICHITA PGY2 OBSTETRICS AND GYNECOLOGY RESIDENCY Dominican Republic 2016
ZIKA VIRUS OUTBREAK JANET B. EDDY M.D. KU-WICHITA PGY2 OBSTETRICS AND GYNECOLOGY RESIDENCY Dominican Republic 2016 Zika time line 1947: 1 st isolated in rhesus monkey in Zika forest of Uganda 1 12/2013:
More informationZIKA VIRUS. Causes, Symptoms, Treatment and Prevention
ZIKA VIRUS Causes, Symptoms, Treatment and Prevention Introduction Zika virus is spread to people through mosquito bites. The most common symptoms of Zika virus disease are fever, rash, joint pain, and
More informationZika Virus and Prevention in Mississippi
Mississippi State Department of Health Mississippi Morbidity Report Volume 32, Number 1 July 2016 Background: Zika Virus and Prevention in Mississippi Key Messages: Zika virus infection during pregnancy
More informationWhat is Zika virus? What are the symptoms and complications of Zika virus infection? Are cases expected in Canada?
What is Zika virus? Zika Virus Update for Healthcare Professionals Updated June 22, 2016; italicized text indicates clarification of wording contained in previous versions. Zika virus is a Flavivirus transmitted
More informationZika. Nicole Evert, MS Zoonosis Control Branch Department of State Health Services Austin, Texas
Zika Nicole Evert, MS Zoonosis Control Branch Department of State Health Services Austin, Texas Family Flaviviridae, genus Flavivirus Vectors: Aedes aegypti and Aedes albopictus Maintained in a human-mosquito-human
More informationCarol M. Smith, M.D., M.P.H. Commissioner of Health and Mental Health Ulster County Department of Health and Mental Health May 20, 2016
Carol M. Smith, M.D., M.P.H. Commissioner of Health and Mental Health Ulster County Department of Health and Mental Health May 20, 2016 Michael Hein County Executive Zika virus was first discovered in
More informationMosquito Control Update. Board of County Commissioners Work Session February 16, 2016
Mosquito Control Update Board of County Commissioners Work Session February 16, 2016 1 Presentation Overview Mosquito Control Division Mosquito-borne Diseases Control Techniques Outlook 2 Mosquito Control
More informationTHE ZIKA VIRUS. August 3, Sonia G. Pandit, MPH MBA Chief Executive Officer The Pandit Group
THE ZIKA VIRUS August 3, 2016 Sonia G. Pandit, MPH MBA Chief Executive Officer The Pandit Group sonia@thepanditgroup.com 443-990-1372 www.thepanditgroup.com What Makes Zika Unique? Viral disease (Flavi
More informationWhen infections go viral Zika Virus
When infections go viral Zika Virus John Fangman, MD Associate Professor of Medicine (Infectious Diseases) Senior Medical Director of Ambulatory, Medical College Physicians Medical College of Wisconsin
More informationEuropean Centre for Disease Prevention and Control. Zika virus disease
European Centre for Disease Prevention and Control Zika virus disease Stockholm, 19 February 2016 Background information Zika virus is a member of the Flaviviridae family and transmitted by mosquitoes
More informationPresentation Overview
Presentation Overview Characteristics of Zika virus Characteristics of Zika virus infection Epidemiology and outbreaks Vector and transmission Clinical symptoms Diagnosis and testing Treatment and prevention
More informationZika Virus and Control Efforts in Arizona
Zika Virus and Control Efforts in Arizona Irene Ruberto, MPH, PhD Epidemiologist Office of Infectious Disease Services Arizona Department of Health Services November 10, 2016 Goal by Humbletree (cc by-nc
More informationGuidance for Investigation and Management of Zika Virus Infection
Guidance for Investigation and Management of Zika Virus Infection Update: February 11, 2016 Public Health Agency of Canada has issued recommendations from the Committee to Advise on Tropical Medicine and
More informationZika Virus in the Primary Care Setting
Zika Virus in the Primary Care Setting Monica McArthur, MD PhD Assistant Professor of Pediatrics Center for Vaccine Development University of Maryland School of Medicine Maryland Chapter ACP Meeting 17
More informationZIKA VIRUS. Epic and aspects of management
ZIKA VIRUS Epic and aspects of management Classification - Belong to the family Flaviviridae which are mosquitoes borne viruses such as Dengue virus ( DEN V ), West Nile virus ( WN V ), Yellow fever Virus
More informationUpdates in Infectious Diseases. Kelley Struble, DO, MS St. John Physicians Infectious Disease September 30, 2016
Updates in Infectious Diseases Kelley Struble, DO, MS St. John Physicians Infectious Disease September 30, 2016 Disclosures No financial relationships or affiliations to disclose Overview Activity Pre-Test
More informationZika Virus Identifying an Emerging Threat. Florida Department of Health in Miami-Dade County Epidemiology, Disease Control, & Immunization Services
Zika Virus Identifying an Emerging Threat Florida Department of Health in Miami-Dade County Epidemiology, Disease Control, & Immunization Services What is Zika Virus? Zika virus is a vector-borne disease
More informationFIRST CONFIRMED CASE OF IMPORTED ZIKA VIRUS IN HOUSTON, TEXAS. Preventing Transmission
FIRST CONFIRMED CASE OF IMPORTED ZIKA VIRUS IN HOUSTON, TEXAS Preventing Transmission Objectives Discuss the epidemiology of Zika virus Describe the Zika case investigation of the first confirmed case
More informationWhat is Zika virus (Zika)?
Zika Virus Basics What is Zika virus (Zika)? Viral infection caused by the bite of an infected mosquito Linked to serious birth defects and other poor pregnancy outcomes in babies of mothers who were infected
More informationOutbreaks of Zika Virus: What Do We Know? Presented by Dr Jonathan Darbro Mosquito Control Lab, QIMR Berhgofer 15 September 2016
Outbreaks of Zika Virus: What Do We Know? Presented by Dr Jonathan Darbro Mosquito Control Lab, QIMR Berhgofer 15 September 2016 Overview History Distribution Modes of Transmission Symptoms Some Causal
More informationZika Virus Update. Florida Department of Health (DOH) Mark Lander. June 16, Florida Department of Health in Columbia County
Zika Virus Update Florida Department of Health (DOH) Mark Lander June 16, 2016 Florida Department of Health in Columbia County 1 Zika Virus Originally identified in Africa and Southeast Asia First identified
More informationZIKA Jordan H. Perlow MD Banner University Medical Center Division of Maternal Fetal Medicine Phoenix Perinatal Asoociates
ZIKA Jordan H. Perlow MD Banner University Medical Center Division of Maternal Fetal Medicine Phoenix Perinatal Asoociates Disclosures I have no relevant financial relationships to disclose or conflicts
More informationTesting - Pregnant Women
Testing - Pregnant Women 81% of women approved for testing in NJ were pregnant In 2017, nearly 95% of pregnant women tested were asymptomatic CDC Updated Testing Recommendations for Asymptomatic Pregnant
More informationWrapping Our Heads Around the Outbreak
Wrapping Our Heads Around the Outbreak An Update on the Zika Virus P. Zach White, PharmD PGY1 Pharmacy Resident Mayo Eugenio Litta Children s Hospital Pharmacy Grand Rounds June 7, 2016 2015 MFMER slide-1
More informationCenters for Disease Control and Prevention Zika Virus in Pregnancy What Midwives Need To Know
Centers for Disease Control and Prevention Zika Virus in Pregnancy What Midwives Need To Know Margaret A. Lampe, RN, MPH Pregnancy and Birth Defects Surveillance Team Zika Virus Emergency Response U.S.
More informationZika virus: a new global threat for Dr Gina McAllister Clinical Scientist, Virology
Zika virus: a new global threat for 2016 Dr Gina McAllister Clinical Scientist, Virology Moritz U. G. Kraemer and others The global distribution of the arbovirus vectors Aedes aegypti and Ae. albopictus
More informationMercer MRC A Newsletter for and about our volunteers
Mercer MRC A Newsletter for and about our volunteers May 2017 Volume 1, Issue 5 Brian Hughes, County Executive Marygrace Billek, Director, Dept. of Human Services Lyme Disease Awareness Month May is Lyme
More informationEpidemiology and entomology of the Zika virus outbreak
Epidemiology and entomology of the Zika virus outbreak M A T T H E W B A Y L I S I N S T I T U T E O F I N F E C T I O N A N D G L O B A L H E A L T H U N I V E R S I T Y O F L I V E R P O O L Zika in
More informationZika Virus Basics. Flaviviridae Flavivirus Disease Vector Vaccine *Dengue (serotypes 1-4) Zika Virus Basics. Zika Virus Transmission Cycle
Zika: Infection,, and Protection Roxanne P. Liles, Ph.D., MLS(ASCP) CM Assistant Professor of Biology Louisiana State University at Alexandria 318-473-6518 rliles@lsua.edu Zika Virus Basics Virion: Enveloped
More informationZika Virus. Lee Green Vector-Borne Epidemiologist Indiana State Department of Health. April 13, 2016
Zika Virus Lee Green Vector-Borne Epidemiologist Indiana State Department of Health April 13, 2016 What Is It? Flavivirus WNV Dengue St. Louis Encephalitis Yellow Fever Tick Borne Encephalitis Single stranded
More informationEverything you ever wanted to know about Zika Virus Disease
Everything you ever wanted to know about Zika Virus Disease (in 14 slides) Jon Temte, MD/PhD University of Wisconsin School of Medicine and Public Health 28 January 2016 Zika Virus mosquito-borne flavivirus
More informationVector-Borne Diseases Update: Maricopa County
Vector-Borne Diseases Update: Maricopa County Craig Levy, Epizoologist, Office of Epidemiology WeArePublicHealth.org twitter.com/maricopahealth facebook.com/mcdph Emerging Arboviruses Zika Virus Chikungunya
More informationMicrobes at Our Doorstep: Emerging issues in infection control and travel-related infections
Microbes at Our Doorstep: Emerging issues in infection control and travel-related infections Peel November 2, 2016 Learning Objectives At the end of this session, participants will be able to: 1. Identify
More informationSPECIALIZED FAMILY CARE Provider Training
SPECIALIZED FAMILY CARE Provider Training Category: Health Issue Title: Zika Virus Materials: Centers for Disease Control Fact Sheet on Zika Virus Goal: Specialized Family Care Provider to learn the risks,
More information3/24/2017. CDC S Response to Zika ZIKA 101. Updated February 2, 2017 INTRODUCTION
CDC S Response to Zika ZIKA 101 Updated February 2, 2017 INTRODUCTION 1 What is Zika? Zika virus is spread to people primarily through the bite of an infected Aedes species mosquito (Ae. aegypti and Ae.
More informationZika virus: Interim guidance information for LMCs (midwives), GPs and other health professionals dealing with Zika virus in pregnancy 5 February 2016
Zika virus: Interim guidance information for LMCs (midwives), GPs and other health professionals dealing with Zika virus in pregnancy 5 February 2016 This interim guidance is the result of consultation
More informationZika Virus. Division of Infectious Disease Department of Internal Medicine Global Health Program Conference Dora Lebron, MD Alexandra Stang, MD
Zika Virus Division of Infectious Disease Department of Internal Medicine Global Health Program Conference Dora Lebron, MD Alexandra Stang, MD Zika Virus ZIKV is a mosquito-borne ssrna flavivirus from
More informationZika Virus. Robert Wittler, MD
Zika Virus Robert Wittler, MD Disclosure I have no relevant financial relationships with the manufacturers(s) of any commercial products(s) and/or provider of commercial services discussed in this CME
More informationZika Virus. Disclosure. Zika Virus 8/26/2016
Zika Virus Robert Wittler, MD Disclosure I have no relevant financial relationships with the manufacturers(s) of any commercial products(s) and/or provider of commercial services discussed in this CME
More informationGeneral Description. Significance
General Description The Zika virus is a member of the Flavivirus family, and is a small, enveloped virus (easy to kill with a hospital disinfectant). Zika virus is an emerging mosquito-borne virus that
More informationWaiting in the Wings: Emergence, Impact and Control of Mosquito-Borne Viruses
International Center for Enterprise Preparedness (InterCEP) Waiting in the Wings: Emergence, Impact and Control of Mosquito-Borne Viruses Web Forum On April 14, 2016, Kathryn A. Hanley, Professor in the
More informationZIKA COLLABORATION MEETING: CLINICAL PERSPECTIVE. Julius L. Tonzel Vector-borne Diseases Epidemiologist Louisiana Office of Public Health
ZIKA COLLABORATION MEETING: CLINICAL PERSPECTIVE Julius L. Tonzel Vector-borne Diseases Epidemiologist Louisiana Office of Public Health DISCLOSURE STATEMENT The speakers, the speakers spouses, and the
More informationAnnual Epidemiological Report
August 2018 Annual Epidemiological Report 1 Vectorborne disease in Ireland, 2017 Key Facts 2017: 10 cases of dengue were notified, corresponding to a crude incidence rate (CIR) of 0.2 per 100,000 population
More informationTown of Wolfeboro New Hampshire Health Notice Wolfeboro Public Health Officer Information Sheet Zika Virus
Aedes Zika Virus Information Sheet Town of Wolfeboro New Hampshire Health Notice Wolfeboro Public Health Officer Information Sheet Zika Virus The Zika Virus is a mosquito borne illness spread by the Aedes
More informationZika Virus A Public Health Emergency of Olympic Proportions
Zika Virus A Public Health Emergency of Olympic Proportions Carrie L. Byington M.D.** HA and Edna Benning Presidential Professor Division of Pediatric Infectious Diseases ** With Thanks to Andrew Pavia,
More informationWhat You Need to Know ZIKA VIRUS
What You Need to Know ZIKA VIRUS What is Zika Virus? Zika virus is a flavivirus related to dengue, West Nile, yellow fever and Japanese encephalitis Zika virus first identified in 1947 and named for the
More informationZika Virus: Epidemiology and Preparedness NH Emergency Preparedness Conference June 9, 2016
Zika Virus: Epidemiology and Preparedness NH Emergency Preparedness Conference June 9, 2016 Abigail Mathewson, DVM, MPH Surveillance Epidemiology Program Manager State Public Health Veterinarian Abigail.mathewson@dhhs.nh.gov
More informationZika Virus. Frequently Asked Questions: Zika Virus and Pregnancy Version
Zika Virus Frequently Asked Questions: Zika Virus and Pregnancy Version What is Zika? Zika is a viral infection that usually causes a mild illness that typically lasts between 2 and 7 days. 80% of people
More informationFY 2017 President s Budget Request Overview for the National Center on Birth Defects and Developmental Disabilities
National Center on Birth Defects and Developmental Disabilities FY 2017 President s Budget Request Overview for the National Center on Birth Defects and Developmental Disabilities Sascha Chaney Associate
More informationKILLER BITES: Mosquito-Borne Viruses Jon Mark Hirshon, MD, MPH, PhD
KILLER BITES: Mosquito-Borne Viruses Jon Mark Hirshon, MD, MPH, PhD Professor, Department of Emergency Medicine University of Maryland School of Medicine Disclosures Conflicts of Interest: Pfizer consultant
More informationZIKA VIRUS TESTING GUIDANCE, UPDATED 7/20/2016
Section 1: Which patients should be offered testing? SUMMARY OF CATEGORIES OF PATIENTS WHO SHOULD BE TESTED FOR ZIKA 1) Pregnant women who traveled to a Zika-affected area (see link to current list in
More informationFact Sheet for Health Care Providers: Interpreting Results from the Aptima Zika Virus assay. September 7, 2016
Dear Health Care Provider: Fact Sheet for Health Care Providers: Interpreting Results from the Aptima Zika Virus assay September 7, 2016 The U.S. Food and Drug Administration (FDA) has issued an Emergency
More informationSurveillance Protocol Dengue Fever (Breakbone fever, Dengue Hemorrhagic Fever)
Surveillance Protocol Dengue Fever (Breakbone fever, Dengue Hemorrhagic Fever) Provider Responsibilities 1. Report suspect or confirmed cases of Dengue Fever (DF) or Dengue Hemorrhagic Fever (DHF).to your
More informationDuane J. Gubler, ScD Professor and Founding Director, Signature Research Program in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore
Duane J. Gubler, ScD Professor and Founding Director, Signature Research Program in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore AGENDA Other arboviruses with the potential for urban
More informationWhere is Yellow Fever found?
Yellow Fever Introduction Yellow Fever is an acute viral hemorrhagic disease transmitted by a female mosquito of the Aedes family (Aedes aegypti). Man and monkeys are the only reservoir for this virus.
More informationARIZONA ARBOVIRAL HANDBOOK FOR CHIKUNGUNYA, DENGUE, AND ZIKA VIRUSES
ARIZONA ARBOVIRAL HANDBOOK FOR CHIKUNGUNYA, DENGUE, AND ZIKA VIRUSES 7/31/2017 Arizona Department of Health Services P a g e 1 Arizona Arboviral Handbook for Chikungunya, Dengue, and Zika Viruses OBJECTIVES...
More informationUpdated Information Zika Virus Testing Guidelines
Updated Information Zika Virus Testing Guidelines To: From: Clients of UR Medicine Labs Dwight J. Hardy, PhD Director, UR Medicine Clinical Microbiology Laboratories Phone: (585) 275-1408 Email: dwight_hardy@urmc.rochester.edu
More informationQuarte. FOCUS: Zika. March Volume. Zika Virus. is present. reached. can cause. low, with. in the
COMMUNICABLE DISEASE REPORT Quarte erly Report Volume 33, Number 1 March 2016 FOCUS: Zika Virus, Hepatitis A, Listeriosis Zika Virus Zika Virus (ZikV) has recently been classifiedd as a significant public
More informationZIKA PRESENTED BY DENNIS QUERTERMOUS, DIANNA HUNTER, MERCEDES RUTLEDGE, AND DRE'ANDRIA THOMPSON
ZIKA PRESENTED BY DENNIS QUERTERMOUS, DIANNA HUNTER, MERCEDES RUTLEDGE, AND DRE'ANDRIA THOMPSON ZIKA OVERVIEW Family: Flaviviridae Genus: Flavivirus Enveloped, single-stranded RNA virus First identified
More informationMosquito Control Matters
Mosquito Control Matters Gary Goodman General Manager Sacramento-Yolo Mosquito & Vector Control District Sacramento Yolo Mosquito & Vector Control District To provide safe, effective and economical mosquito
More informationCHIKUNGUNYA VIRUS INFECTION. Cesar Ponce S. Medical Microbiologist and Parasitologist. Epidemiologist ADC Medical Microbiology Department Director
CHIKUNGUNYA VIRUS INFECTION Cesar Ponce S. Medical Microbiologist and Parasitologist. Epidemiologist ADC Medical Microbiology Department Director Curacao, Aug. 2014 TOPICS: Definition History Epidemiology
More information*This response is constantly evolving and recommendations in this presentation may change over time, please call your district epidemiologist or a
*This response is constantly evolving and recommendations in this presentation may change over time, please call your district epidemiologist or a GDPH epidemiologist 404-657-2588, 8-5 pm M-F for current
More informationCDC Responds to ZIKA Zika 101
CDC Responds to ZIKA Zika 101 Updated April 29, 2016 What is Zika virus disease (Zika)? Disease spread primarily through the bite of an Aedes species mosquito infected with Zika virus. Many people infected
More informationZika Preparedness: Lessons for the U.S. Public Health System
Zika Preparedness: Lessons for the U.S. Public Health System Jeffrey Duchin, MD Health Officer, Public Health - Seattle & King County Professor in Medicine, Division of Infectious Diseases Adjunct Professor,
More informationZika virus: clinical and epidemiological features
Zika virus: clinical and epidemiological features Dominic Dwyer Medical Virologist, Westmead Hospital Director, ICPMR and Pathology West NSW Health Pathology dominic.dwyer@sydney.edu.au, Zika virus Flavivirus
More informationGeographic distribution ZIKV
Shelley M. Wood, RN, BSN, CEN March 16, 2016 Geographic distribution ZIKV 1947 2007 http://www.ncbi.nlm.nih.gov/pmc/articles/pmc2819875/ 1 Current Active Zika transmission WHO declared global health threat
More informationAlberta Health Public Health Notifiable Disease Management Guidelines March 2017
March 2017 Dengue Revision Dates Case Definition Reporting Requirements Epidemiology/Public Health Management Case Definition March 2017 March 2017 March 2017 Confirmed Case Laboratory confirmation of
More informationFact Sheet. Zika Virus
Fact Sheet Zika Virus The following provides information on the use and containment of Zika virus (ZIKV). Investigators should use these guidelines as part of their risk assessment when planning experiments
More informationZIKA AND MOSQUITO- BORNE ILLNESSES
ZIKA AND MOSQUITO- BORNE ILLNESSES Steven M. Presley, Ph.D. Professor, Environmental Toxicology São Paulo Research Foundation (FAPESP) Week 21 & 22 September 2017 BIOLOGICAL THREAT RESEARCH LABORATORY
More informationZika and Emerging Infectious Diseases. Clifford T. Mauriello, MD, FAAP Assistant Clinical Professor May 31, 2016
Zika and Emerging Infectious Diseases Clifford T. Mauriello, MD, FAAP Assistant Clinical Professor May 31, 2016 Famous Last Words The time has come to close the book on infectious diseases. We have basically
More informationZika Virus Dr Conor Doherty
Zika Virus Dr Conor Doherty Zika Virus Single stranded RNA enveloped icosahedral virus Flavivirus (e.g. dengue, yellow feve er) First described in Zika forest in Uganda in 1947 Initial enzootic monkey
More informationArboviruses in Florida. Carina Blackmore, DVM, PhD Florida Department of Health Bureau of Environmental Public Health Medicine
Arboviruses in Florida Carina Blackmore, DVM, PhD Florida Department of Health Bureau of Environmental Public Health Medicine Arboviruses in Florida Flaviviruses West Nile St. Louis Encephalitis Alphaviruses
More informationZika Virus Outbreak An Update and Overview of the New York State Response
Zika Virus Outbreak An Update and Overview of the New York State Response Elizabeth Dufort, MD, FAAP Medical Director Division of Epidemiology New York State Department of Health Zika Virus- The Basics
More informationSeroprevalence and Recent Trends of Dengue in a Rural Area in South India
International Journal of Current Microbiology and Applied Sciences ISSN: 2319-7706 Volume 6 Number 1 (2017) pp. 36-41 Journal homepage: http://www.ijcmas.com Original Research Article http://dx.doi.org/10.20546/ijcmas.2017.601.005
More informationFight the Bite Zika Virus Webinar District of Columbia Department of Health
Fight the Bite Zika Virus Webinar District of Columbia Department of Health August 2016 Zika Virus Background and Tracking in Washington, DC, and Surrounding States Andrew Hennenfent, DVM, MPH DC Department
More informationEmerging TTIs How Singapore secure its blood supply
Emerging TTIs How Singapore secure its blood supply Ms Sally Lam Acting Division Director I Blood Supply Management I Blood Services Group I Health Sciences Outline Risk Mitigation Strategies to secure
More informationZika Update. Florida Department of Health Broward. Paula Thaqi, MD, MPH Director
Zika Update Florida Department of Health Broward 1 Paula Thaqi, MD, MPH Director Zika Virus Over 750,000 reported cases in the Americas Over 36,000 cases in U.S. territories Over 5,000 imported case sin
More informationMosquito Threats in LA County West Nile virus & Zika
Mosquito Threats in LA County West Nile virus & Zika The District at a Glance An independent special district formed under authority of the CA State Health and Safety Code Formed in 1952 and governed by
More informationAAP ZIKA ECHO (EXTENSION FOR COMMUNITY HEALTHCARE OUTCOMES)
AAP ZIKA ECHO (EXTENSION FOR COMMUNITY HEALTHCARE OUTCOMES) HOUSEKEEPING ITEMS For educational and quality improvement purposes, this ECHO session will be recorded Project ECHO collects participation data
More informationZika 101 for Occupational Safety and Health Professionals
CDC Responds to ZIKA Zika 101 for Occupational Safety and Health Professionals CDR Jill M. Shugart, MSPH, REHS CDC/National Institute for Occupational Safety and Health Emergency Preparedness and Response
More information