Avian Influenza Outbreak in Thailand Chantanee Buranathai
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1 Avian Influenza Outbreak in Thailand 2004 Chantanee Buranathai
2 Before 2004
3 Laboratory Surveillance for HPAI # Sample Result Passive 3600 All negative Active (Slaughter H.) Active (Others) 23, All negative All negative
4 Slaughter house surveillance for HPAI Year No. of samples Results ,424 All negative ,648 All negative ,588 All negative Note : one sample is a pooled cloacal swabs from 5 chickens
5 !Highly Pathogenic Avian Influenza of subtype H5 was first isolated and confirmed in Thailand in January 2004
6 The First HPAI case 23/01/2004
7 Emergency Response for Avian Influenza Outbreak in Thailand
8 Three phases of HPAI outbreak in Thailand HPAI outbreak in Thailand was first recognized in January The etiologic pathogen was H5N1. Situation of the outbreak, measures taken were summarized into 3 phases 1. Initial phase: immediately after the recognition of the disease 2. Expansion phase: the duration after stamping-out and preemptive actions were taken 3. Finalized phase: the time after preemptive culling was stopped, sporadic cases were detected based on case definition and clinical signs
9 First phase : Initial Phase! Emergency response right after HPAI was recognized! Initial surveillance! Role of laboratory! Control and Prevention measures
10 Initial Surveillance! Duration: Jan 04! Area : every village, farm in the country! Sampling: 95% CI! No.samples: 75,623! Samples: Cloacal swabs for virus isolation
11 Initial Surveillance Results:! 161 cases (village, farm) in 71 districts, 40 provinces found positive
12 Actions Taken during the initial phase! Stamping-out and disinfected of infected premises! Preemptive culling of poultry within 5 km radius from infected premises! Movement control (area km radius from infected premises) Check HPAI 10 days before catching date Only negative farms could obtain movement permit from the DLD Ante-mortem check at the slaughter houses by collecting cloacal swabs to recheck for AIV Product check: all poultry products were sampling and checked for AIV Ante-mortem and product check must be negative in order to obtain health certificate for export from the DLD
13 2 nd Phase: Expansion of Surveillance! Duration: 11 Feb - 4 March 04! Areas surrounding stamped out zone (>5-10 Km radius) 2nd surveillance zone Stamped-out zone! Suspected areas (eg. low production, cases or deaths with other disease)
14 Second Surveillance! 95 % CI! No. of samples :12,000! Samples: cloacal swaps for virus isolation! Map shows locations
15 Result of the Second Surveillance! 18 new cases found (blue dots)! 17 cases located in the previously positive provinces (40 provinces)! One new case in one new province (Rot Et)! Red dots indicate previously positive cases
16 Actions Taken during the second phase! Stamping-out and disinfected of infected premises! Preemptive culling of poultry within 1 km radius from infected premises! Movement control (all over the country) Check HPAI 10 days before catching date Only negative farms could obtain movement permit from the DLD Ante-mortem check at the slaughter houses by collecting cloacal swabs to recheck for AIV Product check: all poultry products were sampling and checked for AIV Ante-mortem and product check must be negative in order to obtain health certificate for export from the DLD
17 3rd Phase: Finalized Phase! Duration: 4 March 04 present! Active clinical surveillance! Stamping-out suspected farm within 24 hr. based on case definition
18 Clinical Presentation! Different from previously reported! Daily mortality rate is lower! Infected birds show no clinical signs! Death bird doesn t shed virus in feces! Symptomatic birds shed virus in feces! Mortality and morbidity in duck (some areas)
19 Clinical signs Sudden death Convulsion, twisted neck Diarrhea Swollen face Congestion and cyanosis of comb and wattle Hemorrhage of the shank Watery eyes Respiratory distress Sinusitis Goose : Cloudy or opaque eyes Duck : Swollen head 71.6 % 20.2% 19.3% 20.2% 31.2% 2.8 % 11.9% 23.9% 2.8%
20 Active Clinical Surveillance! Symptoms Sudden death 70%, neuro 20%, GI 20%, resp 20%...! Case definition (6) death >10% /d, acc. death > 40% / 3 d! Criteria 1, 2+5, 3+5, 4+5, 6! Stamp-out suspected farms based on clinical (within 24 hr)
21 Third Surveillance # #! 10 more cases were found and stampedout, as shown by the red dots! Movement control, Slaughterhouse sampling, product checking have been conducted all over the country # # # # # # # # N W E S
22 Current situation week 1 Week 2 Week 3 Week 4 Week 5 Week 6 Week 7 Week 8 Week 9 Week 10 Week 11 Week 12 Week 13 Week 14 Week 15 Week 16 Week 17 Week 18 Week
23 Current situation! The last HPAI suspected farm was stamped-out and disinfected on 24 May 2004.! No new outbreak was detected for more than 3 weeks then one isolated case was reported in Chiangmai! Pre-movement check, movement control, antemortem and product checked are still carried out nationwide for early detection and monitoring! Sero-surveillance will be conducted soon in order to identify risk areas, evaluate and monitor the prevention and control program.
24 ! Vigilant (adj.)! Vigilance (n.) 1. Keenly watchful to detect danger and trouble 2. Ever awake or alert 3. + alert + active + ready to response + skill to response
25 Stay Vigilant!!
26 Thank you for your attention Sawasdee
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