EXTERNAL TEMPORARY PACEMAKERS

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1 Czech Republic EXTERNAL TEMPORARY PACEMAKERS Lukas Peter Engineering and Business Coordinator Pavel Taborsky Chief Executive Officer

2 MEDIATRADE s.r.o. PRAGUE Valasske Mezirici

3 MEDIATRADE s.r.o. More than 20 years of tradition the company has been producing medical devices since 1994 RESEARCH DEVELOPMENT REALIZATION Specialization in pulse generators external pacemakers PRODUCTION DISTRIBUTION SERVICE International distribution Poland, Iran, Turkey, Vietnam, Cuba,

4 Motivation The company is focused on pulse generators comfort for the patient safety for the heart muscle ergonomic for the medical doctor intuitive handling Cooperation with medical doctors our products are continuously improved How can be the handling easy? What kind of benefits our models have? Why is the use of our external pacemaker advantageous?

5 EPG 10 FAMILY The basic parameters The handling The basic alarms EPG 10 models Summary

6 EPG 10 family One chamber external pacemakers can be used for patients with paroxysmal asystole or chronic supraventricular arrhythmias to treat bradycardia to protect the patient in course of surgery for patients who are not usable dual-chamber pacing Stimulation in atrium or in ventricle Can be found departments of Internal Medicine departments of Cardiac Surgery departments of Cardiology Anesthesiology and Resuscitation departments

7 Amplitude [V] EPG 10MO STIMULATION MODES Type of the stimulus Amplitude of the stimulus Width of the stimulus Frequency of the stimulation Overdrive frequency Battery life VVI, V00, AAI, A00 Monophasic 0 14 V (0 28 ma) ms ppm 5 x 1000 hours time [ms] INDICATORS OPTIC, ACOUSTIC ON/OFF blue LED Disconnection orange LED QRS green/red LED Removing battery Red LED PROTECTION Defibrillation, electrocoagulation, runaway

8 Amplitude [V] EPG 10B STIMULATION MODES Type of the stimulus Amplitude of the stimulus Width of the stimulus Frequency of the stimulation Overdrive frequency Battery life VVI, V00, AAI, A00 Biphasic 0 14 V (0 28 ma) ms ppm 5 x 1000 hours time [ms] INDICATORS OPTIC, ACOUSTIC ON/OFF blue LED Disconnection orange LED QRS green/red LED Removing battery Red LED PROTECTION Defibrillation, electrocoagulation, runaway

9 EPG 10M STIMULATION MODES Type of the stimulus Amplitude of the stimulus Width of the stimulus Frequency of the stimulation Overdrive frequency Battery life VVI, V00 Biphasic 0 14 V (0 28 ma) ms ppm 5 x 1000 hours INDICATORS OPTIC, ACOUSTIC ON/OFF blue LED Disconnection orange LED QRS green/red LED Removing battery Red LED PROTECTION Defibrillation, electrocoagulation, runaway

10 EPG 10 family THE BASIC PARAMETERS The handling The basic alarms EPG 10 models Summary

11 Intuitiveness The basic parameters STIMULATION MODES VVI, V00, AAI, A00 SENSITIVITY of the inhibition mv AMPLITUDE of the stimulus 0 14 V/ 500Ω WIDTH of the stimulus ms FREQUENCY of the stimulation ppm OVERDRIVE frequency of the stimulus 5x

12 Stimulation modes Asynchronous modes A00, V00 without monitoring of cardiac activity, without inhibition Inhibited modes AAI, VVI with monitoring of cardiac activity, with inhibition the chamber is stimulated if there is non chamber events based on inhibitory time The same principle for atrium and ventricle, difference in sensitivity of monitoring Stimulation Refractory period Inhibition

13 EPG 10 family The basic parameters THE HANDLING The basic alarms EPG 10 models Summary

14 Sensitivity SENS Amplitude Amplitude Amplitude 1.2 mv 0.5 mv SENSITIVITY of monitoring Time 1.2 mv 1 mv SENSITIVITY of monitoring Time 5 mv SENSITIVITY of monitoring 1.2 mv Time

15 Amplitude [V] Frequency - RATE Frequency 0.3 Hz RATE - 20 ppm 3.3 s 0 time [s] Amplitude [V] Amplitude [V] Frequency 0.8 Hz RATE - 70 ppm 1.25 s 0 time [s] Frequency - 2 Hz RATE ppm 0.5 s 0 time [s]

16 Amplitude [V] Amplitude - PACE E = U2 R t 0 V time [s] 5 V 10 V

17 Amplitude [V] Width of impulse - PULSE E = U2 R t 0.05 ms 0.2 ms 1 ms time [s]

18 Overdrive RATE 5x Increase of stimulation frequency ppm Atrium only Physiological defibrillation

19 Motivation EPG 10 family The basic parameters The handling THE BASIC ALARMS EPG 10 models Summary

20 Intuitiveness The basic alarms OK BAT blue LED fully functional state red LED discharged/disconnected battery PACING flashing yellow LED indicates pacing SENSITIVITY flashing green LED patient s heart activity flashing red LED OVER VOLTAGE wrong application of the electrode DISCONNECT flashing orange LED disconnection of the electrode

21 OK/BAT Fully functional state optical blue LED acoustic beep Discharge/disconnect optical red LED acoustic intense beeping Time of changing of battery 30 s

22 Sensitivity Amplitude Amplitude Detection QRS complex flashing green LED SENSITIVITY of monitoring Time Over voltage of QRS complex flashing red LED SENSITIVITY of monitoring Time

23 Sensitivity Wrong application of electrode flashing red LED Minimization of the heart wall preformation visual indication of the excessive pressure of the catheter against the heart wall

24 Pacing It is connected with stimulation Signalization of each stimulus flashing yellow LED

25 Disconnect Disconnection of contacts Flashing yellow LED

26 EPG 10 family The basic parameters The handling The basic indicators EPG 10 models Summary

27 EPG 10N STIMULATION MODES Type of the stimulus Amplitude of the stimulus Width of the stimulus Frequency of the stimulation Battery life VVI, V00 Monophasic, rectangular 0 4 ma ms Hz 500 hours Finding of the nerve position

28 The basic parameters The handling The basic indicators EPG 10 models SUMMARY

29 Advantages over competitors Discharging of battery the device has a visual and acoustic indication of discharged battery 24 hours in advance Any polarity while inserting the battery Indication of the optimum adjusted values the optimum adjustment for cardiac pacing of about 95 % of patients

30 Advantages over competitors Minimization of the heart wall preformation the visual indication of the excessive pressure of the catheter against the heart wall An electrode wedged in an optimum way indicated by sense diode risk of the heart wall perforation is indicated by a red SENS diode Different types of stimulation impulses monophasic biphasic

31 Advantages over competitors Monitoring of intracardial ECG digital monitoring - unique software high sensitivity of our device precise monitoring of intracardial ECG Stable current source for generation of stimulation pulses more safety for the heart muscle Adjustable width of stimulation pulse stimulation is based on the energy - time of pulse times amplitude of the pulse

32 Czech Republic THANK YOU FOR YOUR ATTENTION Lukas Peter Engineering and Business Coordinator Pavel Taborsky Chief Executive Officer

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