Premixed Bioceramic Endodontic Materials

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1 Premixed ioceramic Endodontic Materials

2 SELER THE "STTE-OF-THE-RT" IN ENOONTI OTURTION HS HNGE! Unlike conventional base/catalyst sealers, TotalFill Sealer utilizes the moisture naturally present in the dentinal tubules to initiate its setting reaction. This highly radiopaque and hydrophilic sealer forms hydroxyapatite upon setting and chemically bonds to both dentin and to our bioceramic points (TotalFill Points ). Sealer is anti-bacterial during setting due to its highly alkaline ph and unlike traditional sealers, Sealer exhibits absolutely zero shrinkage! Never before has an obturation system been able to make these claims. How does your current system compare? Sealer & Points Your urrent System iocompatible and Osteogenic? hemical ond of Sealer to entin? hemical ond of Sealer to Filling Material? ost Effective (onsiderably Less Expensive Than arriers)? Highly ntibacterial (+12 ph upon setting)? Highly Radiopaque? Hydrophilic? Hydroxyapatite Producing? Ideal Working and Setting Time? User Friendly (Premixed Syringeable Sealer)? Zero shrinkage of Sealer and Filing Material? 3- onded Obturation at Room Temperature? These products represent a major advance in bonded root filling restorations. high ph during setting, biocompatibility when set and dimensional stability are important advantages over traditional root canal sealers. - r. Martin Trope linical Professor, University of Pennsylvania omposition: alcium silicates, alcium phosphate monobasic, zirconium oxide, tantalum oxide and thickening agents.

3 ph Value HIGHLY NTITERIL TotalFill Sealer is alkaline (+12pH) making it highly antibacterial. recent study showed that TotalFill Sealer killed Enterococcus faecalis within 2 minutes of contact. ntibacterial (ph) omparison (at 1 day) Zhang H, Shen Y, Ruse N, Haapasalo M. ntibacterial activity of endodontic sealers by modified direct contact test against enterooccus faecalis. JOE. 2009; 35(7): Sealer H Plus pexit Plus EndoREZ Epiphany Sealaplex Tubli-Seal ontact ngle EXELLENT FLOW TotalFill Sealer s extremely small particle size and hydrophilic nature allow it flow into all aspects of the canal anatomy. recent study proved that TotalFill Sealer has a contact angle which is lower than all other sealers tested. This unique feature of TotalFill Sealer improves its ability to bond to dentin and obturation materials and also improves its ability to effectively kill microbes throughout all aspects of the root canal system. ontact ngle omparison (at 7 days) Zhang H, Shen Y, Ruse N, Haapasalo M. ntibacterial activity of endodontic sealers by modified direct contact test against enterooccus faecalis. JOE. 2009; 35(7): Sealer H Plus pexit Plus EndoREZ Epiphany Sealaplex Tubli-Seal SUPERIOR IOOMPTIILITY TotalFill Sealer is essentially a root repair material with a flowable consistency. The unique osteogenic properties of TotalFill Sealer make it particularly effective on non-vital cases with extensive bone loss or apical periodontitis. recent study showed TotalFill Sealer to be much more biocompatible than H Plus. ytotoxicity Score ytotoxicity Ranking lassification (based on Lodien et al. 2008): = non cytotoxic = slightly cytotoxic = moderately cytotoxic = severely cytotoxic ytotoxicity omparison (at 24 hours) Zhang W, Li Z, Peng. Ex vivo cytotoxicity of a new calcium silicate-based canal filling material. International Endodontic Journal. 2010; 43(9): 769. OI: /j Negative ontrol (0.0) ProRoot MT (0.0) Sealer TM H Plus Positive ontrol SUPERIOR ONING TotalFill Sealer s hydrophilic/hydroxyapatite producing formula and excellent flowability allow it bond readily to both dentin and to bioceramic filling materials ( Points ). recent study showed that TotalFill Sealer has superior bond strength when compared to other popular sealers. The study varied the moisture content to determine its effect on bond strengths. TotalFill Sealer outperformed all the other sealers at all moisture levels. Push-Out ond Strength (MP) ond Strength omparison in ifferent Moisture onditions = Sealer + Gutta Percha = H Plus + Gutta Percha = MT-Fillapex + Gutta Percha = Epiphany + Resilon ry (Ethanol) Normal (Paper Points) Moist Wet Nagas E, Uyanik MO, Eymirli, ehreli Z, Vallittu PK, Lassila LVJ, urmaz V. entin moisture conditions affect the adhesion of root canal sealers. JOE. 2011; 38 (2): 240-4

4 OTURTION KIT IOERMI ONE OTURTION Unlike traditional points, TotalFill Points are subjected to a patented process of impregnating and coating each cone with bioceramic nanoparticles. The bioceramic particles found in TotalFill Sealer bond with the bioceramic particles in TotalFill Points to form a true gap-free seal. recent study showed that TotalFill Sealer, when used in conjunction with our impregnated and coated cones, actually increased the fracture resistance to a level comparable to that of teeth that have not undergone root-canal therapy! Mean Force (N) Fracture Resistance omparison Ghoneim G, Lutfy R, Sabet NE, Fayyad M. Resistance to fracture of roots obturated with novel canal-filling systems. JOE. 2011; 37 (11): Negative ontrol (No Root anal Therapy) TotalFill Sealer + Impregnated/ oated Point TotalFill Sealer + Standard Gutta Percha It is universally accepted that microbes require food and space to survive and multiply. Therefore the primary goal of obturation should be to completely fill and seal the entire canal thereby eliminating any gaps (this includes the gap between the sealer and the filling material). The below SEMs visually confirm TotalFill Sealer s unprecedented ability to adapt to the surface of dentin and TotalFill Points. x35 Magnification x200 Magnification x350 Magnification x1000 Magnification SEMs courtesy of Martin Trope M. linical Professor, epartment of Endodontics, School of ental Medicine, University of Pennsylvania. In all my years of viewing high magnification SEMs, I have never seen a sealer form such a consistently intimate bond with dentin. - r. Martin Trope linical Professor, University of Pennsylvania TotalFill Obturation Kit * Order: S01.XX (.04) Order: S01.XX (.06) TotalFill Sealer Syringe: Order: XX * Points are available in individual sizes and in assortment wheels. Pellets are also available for warm vertical obturation. Standard gutta percha can be used, but for a true, gap-free seal, Points are recommended.

5 ROOT REPIR MTERIL TIRE OF HSSLING WITH ONVENTIONL ROOT REPIR MTERILS? Premixed with Superior Handling and Healing Properties, TotalFill Root Repair Material is Ideal for ll Your Root Repair Needs. TotalFill Root Repair Material (RRM ) is available in two specifically formulated consistencies (syringable paste or condensable putty) and contains many of the same characteristics as TotalFill Sealer. The favorable handling properties, increased strength and shortened set time make TotalFill RRM highly resistant to washout and ideal for all root repair and pulp capping procedures. Research and countless cases confirm that TotalFill RRM is highly biocompatible and osteogenic. Join the thousands of others that have set aside their spatulas and joined the TotalFill RRM revolution! SUPERIOR HNLING Premixed-syringable paste or putty consistency Shortened Set Time ~2 hours vs 4+ hours with others Highly Resistant to Washout EXELLENT HELING Highly iocompatible Osteogenic nti-bacterial (+12 ph) TotalFill RRM Syringe Order: XX 1 x 1g Preloaded Syringe 7 x Intra anal Tips MSS Instructions for Use TotalFill RRM Putty Order: XX 2.5g Jar MSS Instructions for Use pplications: Root Endo Filling (Retrograde fills), Repair of Root Perforation, Repair of Root Resorption, pexification, Pulp apping omposition: alcium silicates, alcium phosphate monobasic, alcium hydroxide, Zirconium oxide, Tantalum oxide, Filler and thickening agents.

6 IOTIVE The following SEM images illustrate the similarities between MT and RRM. Group shows the crystalline surfaces of MT and TotalFill RRM. oth surfaces are composed primarily of calcium, carbon and oxygen. More notably, Group shows the extent of human gingival fibroblast adhesion to MT and TotalFill RRM (after 7 days of incubation). Notice the extensive matrix-like overlay on the surface of the RRM. These SEMs visually confirm that TotalFill RRM is highly bioactive and efficiently promotes biomineralization. Group * Group * MT rystaline Surface TotalFill RRM rystaline Surface MT Fibroblast dhesion Jingzhi M, Shen Y, Stojicic S, Haapasalo M. iocompatibility of Two Novel Root Repair Materials. JOE. 2011; 37(6): TotalFill RRM Fibroblast dhesion ell Viability EXELLENT IOOMPTIILITY The following graph illustrates the biocompatibility of TotalFill RRM as compared to other commonly used root repair materials. 120% 100% 80% 60% 40% 20% 0% Elute Medium (300μL) ytotoxicity omparison 3-ay Set Samples Elute Medium (600μL) Elute Medium (1mL) lnezi Z, Jiang J, Safavi KE, Spangberg LSW, Zhu Q. ytotoxicity evaluation of EndoSequence Root Repair Material. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology. 2010; 109(3): OI: /j.tripleo = TotalFill Root Repair Material = Gray MT = White MT = H26 LINIL RIOGRPHS ourtesy: r. li Nasseh H Plus, H26, ProRoot MT, MT-Fillapex, pexit Plus, EndoREZ, Epiphany, Resilon, Sealaplex, and Tubli-Seal are trademarks of their respective owners and are not trademarks of Peter rasseler Holdings, LL, or its affiliates. TotalFill, Sealer, Points, Obturation System and RRM are trademarks of Peter rasseler Holdings, LL, or its affiliates 2013 rasseler US ental, LL, One rasseler lvd Savannah, G US. ll rights reserved. TotalFill RRM root repair material RRM has superior sealability, low cytotoxity and immediate antimicrobial effect. linically TotalFill RRM is easy to use and its application on perforations, open apices and retrograde filling does not require any type of carrier. The material is ready to use and no unnecessary waste is left compared to the traditional material used with the same purposes. - r. Gilberto ebelian djunct Faculty Grad Endo UN, UPenn and University of Oslo US FKG REF EN - 09/ PHOTOS OF OUR PROUTS RE NOT ONTRTUL

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