Cellistypt Oxidized Resorbable Cellulose Hemostats. Biosurgicals
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1 Oxidized Resorbable Cellulose Hemostats Biosurgicals
2 Oxidized Resorbable Cellulose Hemostats Zriusscing Peratldiup DVD-R is an oxidized resorbable cellulose hemostat, of 0 % vegetable origin made from natural cotton. Oxidized cellulose hemostats have been used for decades 1 and are well known for their hemostatic properties and easy handling. B. Braun s product range is available in three different presentations, offering the right option for every indication. Oxidized Resorbable Cellulose 3 presentations available: S-VHS x DVI-D D-K F kg Biocompatible Absorbed in 1-2 weeks 2 Bacteriostatic properties 1,3,4 Easy to use Indicated for capillar and mild venous bleedings 2 1 Schonauer C, Tessitore E, Barbagallo, Albanese V and Moraci A. The use of local agents: bone wax, gelatin, collagen, oxidized cellulose. Eur Spine J. 2004;13(Supple.1): See product IFU.
3 oxidized resorbable cellulose hemostats are meant to be used as adjunt to hemostasis in open surgical and minimal invasive procedures in order to control capillary, minor venous and minor arteriolar bleeding, when conventional hemostatic methods such as ligation are impractical or not effective. supports natural hemostasis though its absorptive capacity and its ability to denaturate proteins, which helps to build a clot to stop bleeding. product range consists of three different presentations: basic format, gauze-like hemostat for mild bleeding. D-K dense knitted format, for superior strength, suitable to wrap organs. F cotton wool which enables the use of the necessary amount only and allows the placement on all kinds of surfaces inlcuding those areas of difficult access. For more infomation see the table below: D-K F Presentation Knitted fabric of regular density Knitted fabric of high density Non-woven, cotton wool format Handling Highly flexible Can be cut or folded Easy to form scarves around anastomosis Improved strength, enables suturing Can be rolled and introduced through the trocar Highly versatile Can be applied in layers of the desired thickness Good control of the amount used Easy to place in difficult to reach areas Indications To stop mild bleedings and oozings in open and minimally invasive procedures To wrap parenchymotous organs To stop bleeding from fragile sternums To stop venous bleeding and oozing especially in areas withdifficult access Stop bleeding from cortical surfaces after tumour resection 3 3 Spangler D, Rothenburger S, Nguyen K, Jampani H, Weiss S, Bhende S. In vitro antimicrobial activity of oxidized regenerated cellulose against antibiotic-resistant microorganisms. Surg Infect (Larchmt). 2003;4(3): Wagner WR, Pachence JM, Ristich J, Johnson PC. Comparative in vitro analysis of topical hemostatic agents. J Surg Res. 1996;66:0-8. 3
4 Antibacterial Activity Oxidized cellulose is known for its action against a wide variety of microorganisms since it creates a low ph area which is hostile for bacteria 1,3,4. This low ph effect is independent from antibiotic mechanisms, so antibiotic resistant bacteria are also affected by antimicrobial activity of oxidized cellulose 1. antimicrobial activity is evaluated in in vitro tests 5. Effect of over Methicilin-Resistant Staphylococcus Aureus (MRSA) after incubation period. Bacterial growth is reduced around samples. Right: piece of with bacteria free halo around. Left: has been removed. There is no bacterial growth were the piece of was placed. Antimicrobial activity is tested by dilution and diffusion method 5. Antimicrobial activity evaluated against, among others, the following microorganisms 5 : Staphylococcus aureus (MRSA) Streptococcus pneumoniae (PRSP) Enterococcus (VRE) Staphylococcus epidermidis (MRSE) Streptococcus Pyogenes group A Streptococcus agalactiae group B Streptococcus salivarius Escherichia coli Corynebacterium xerosis Clostridium perfringens Bacteroides fragilis Enterococcus faecalis Pseudomonas aeruginosa Pseudomonas stutzeri Staphylococcus saprophyticus In vitro test results. Equivalent results in vivo and in clinical use have not been verified. 5 Test performed in Dep. of Biological and Biochemical Sciences, Faculty of Chemical Technology, University of Pardubice, CZ. Full study available, reference number
5 Oxidized Resorbable Cellulose Hemostats Product range Description Code Content 5 cm x 1.25 cm cm x 7 cm cm x cm cm x 35 cm cm x 20 cm cm x 1.5 cm D-K Description Code Content 2.5 cm x 2.5 cm cm x 9 cm cm x 7.5 cm cm x cm cm x 20 cm F Description Code Content 2.5 cm x 5 cm cm x 6 cm 5 cm x cm cm x cm cm x 20 cm
6 Distributed by: B. Braun Surgical, S.A. Carretera de Terrassa, Rubí Spain Phone Fax The product trademark Cellistypt is a registered trademark of Aesculap AG. Aesculap AG Am Aesculap-Platz Tuttlingen Germany Phone Fax Aesculap a B. Braun company Subject to technical changes. All rights reserved. This brochure may only be used for the exclusive purpose of obtaining information about our products. Reproduction in any form partial or otherwise is not permitted. Brochure No. B /1/2
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