Index. Foot Ankle Clin N Am 11 (2006) Note: Page numbers of article titles are in boldface type.

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1 Foot Ankle Clin N Am 11 (2006) Index Note: Page numbers of article titles are in boldface type. A Alpha-lipoic acid, in diabetic neuropathy, 764 Amputation(s), lower-extremity, in diabetes, goal of, 792 incidence of, 791 level of, outcomes of, postamputation care in, surgical decision making for, Angiopathy, in diabetes, Ankle fractures, in diabetics, , fracture management in, history taking for management of, nonoperative versus operative treatment of, physical examination in, 856 preoperative planning in, 856 incidence of, Anti-arrhythmics, in diabetic neuropathy, 767 Antibiotics, and debridement, in osteomyelitis in diabetic foot, Anticonvulsants, in diabetic neuropathy, 765 Antidepressants, in diabetic neuropathy, Antihypertensive therapy, Antioxidant therapy, in diabetic neuropathy, 764 Arthrodesis, in neuropathic arthropathy, 806 Arthropathy, Charcot. See Charcot arthropathy. Aspirin therapy, and cardiovascular disease, 713 B Bacterial overgrowth, as impediment to wound healing, 746 Bone healing, diabetic, impaired, potential mechanisms of, 808 Braces, for diabetic foot, function of, 728 types of, Brannock device, 722 C Calcaneus, Charcot calcaneal recurvatum and, 828, 829 Charcot of. See Charcot arthropathy, of calcaneus. Calcium alginate, in wound healing, Carbamazepine, in diabetic neuropathy, Cardiovascular disease, aspirin therapy and, 713 diabetes mellitus and, Cast walkers, 738 Casts, total contact, 738 Charcot arthropathy, classsification of, 828 debridement and exostectomy in, in diabetes, 851 management of, midfoot, 762, 763 of calcaneus, arthrodesis in, diagnosis of, pathophysiology of, 826 osteomyelitis versus, 781 patterns of injury in, /06/$ - see front matter Ó 2006 Elsevier Inc. All rights reserved. doi: /s (06) foot.theclinics.com

2 866 INDEX Charcot (continued) ring external fixation in. See Ring external fixation, in Charcot arthropathy. Charcot calcaneal recurvatum, 828, 829 Charcot insufficiency fracture, 828 Charcot joints, causes of, 825 in diabetic patients, Charcot restraint orthotic walker, 729 Chopart amputation, 797 Computerized imaging, in manufacture of custom insoles, 739, 740 D Diabetes mellitus, and cardiovascular disease, angiopathy in, ankle fractures in, , as impediment to wound healing, Charcot arthropathy in, 851 Charcot joints in, complications of, 703, 705 cost of, 825 delayed fracture healing in, 852 delayed wound healing in, description of, 849 diagnosis of, 704 fracture healing in. See Fracture healing, diabetic. fractures in, potential for development of, 820 glucose-lowering agents in, hyperglycemia and, 703 immune dysfunction in, 853 incidence of, 753, 849 lower-extremity amputations in. See Amputation(s), lower-extremity, in diabetes. metabolic risk factors for, 711 overview of, pathoetiology of, 753 peripheral neuropathy in, peripheral vascular disease in, types of, 704 Diabetic foot, diabetic foot care team and, 717 osteomyelitis in. See Osteomyelitis, in diabetic foot. pedorthic and orthtic management of, Diabetic foot ulcers, cause of, assessment of, 736 classification of, healing of, and preventing recurrence of, follow-up care by foot care specialist, 740 future development in, 741 in-shoe orthoses for, 739 nonsurgical strategies for, new approaches to, 735 in diabetic neuropathy, 754 off-loading healing wounds in, 738 posthealing management of, total contact casting in, 717 wound treatments in, 737 Diabetic nephropathy, detection of, Diabetic neuropathy, activation of protein kinase C, 757 autonomic, classification of, and clinical manifestations of, glycosylation of proteins and, lipoprotein lipase activity and, microvascular disease and, 758 nerve ion channels and, 758 nerve tissue factors and, 757 neuronal damage and microvascular disease in, pathogenesis of, pharmacologic symptom-based management of, , 768 reactive oxygen species, surgery of, treatment of, ulcerations in, 754 Diabetic retinopathy, detection of, 705 future therapy for, Disease, chronic, as impediment to wound healing, Duloxetine, in diabetic neuropathy, E Exenatide, 712 Exostectomy, in Charcot arthropathy, F Foot, diabetic. See Diabetic foot. Foot orthoses. See Orthosis(es). Footwear. See Shoe(s).

3 Fracture(s), Charcot insufficiency, 828 in diabetic patients, potential for development of, 820 of ankle, in diabetic patients. See Ankle fractures, in diabetics. incidence of, Fracture healing, diabetic, adjuncts to, clinical studies in, delayed, 852 experimental studies in, growth factors and, insulin in, 809 physiologic glucose control and, surgical technique in, G Gabapentin, in diabetic neuropathy, 765 Gauze, impregnated, in wound healing, 747 Glucose control, physiologic, diabetic fracture healing and, Glucose-lowering agents, in diabetes mellitus, Growth factors, and diabetic fracture healing, Guillotine amputation, 799, 800 H Hydrocolloids, in wound healing, 748 Hydrogels, in wound healing, 748 Hyperbaric oxygen therapy, in wound healing, 750 Hyperglycemia, and diabetes mellitus, 703 I Immune dysfunction, in diabetes, 853 Incretin mimetics, Infections of foot, diabetes-related, biopsy and bone culture in, clinical evaluation of, cost of, 775 evaluation of, imaging studies in, 779 laboratory studies in, 779 microbiology of, pathophysiology of, 776 Insoles, custom, manufacture of, computerized imaging in, 739, 740 INDEX Insulin, in bone healing, 809 Insulin resistance syndrome, 709 L Lipid-lowering therapy, 712 Lipoprotein ppilase activity, diabetic neuropathy and, Lisfranc amputations, M Metabolic syndrome, Metformin, 711 Microvascular disease, diabetic neuropathy and, 758 N Negative pressure wound therapy, 737 Nephropathy, diabetic, detection of, peripheral, detection of, 708 painful neuropathy in, 709 prevention strategies in, Nerve ion channels, diabetic neuropathy and, 758 Neuropathy, diabetic. See Diabetic neuropathy. peripheral, in diabetes, Nonadherent dressings, in wound healing, Norepinephrine, and selective serotonin reuptake inhibitors, in diabetic neuropathy, Nutritional deficiencies, as impediment to wound healing, 747 O Opioids, in diabetic neuropathy, 766 Orthosis(es), accommodative, materials for, 725 molding of, patient for, 724 component objectives of, 724 custom-made, 723 in-shoe, manufacture of, 739, 740 ulcer healing, 739 molded plastic ankle foot, 728 off-the-shelf, 728 rigid, 727

4 868 INDEX semirigid, concept behind, 726 layers in, 725 materials used for, triple-layer, 727 types of, Orthotist, certified, role in diabetic foot care, Osteoarthropathy, neuropathic, osteomyelitis versus, 781 Osteomyelitis, and ring external fixation in Charcot arthropathy, 842 in diabetic foot, 737 antibiotics and debridement in, diagnosis and management of, multidiscipline management of, 782 surgical management of, treatment of, versus Charcot arthropathy, 781 versus neuropathic osteoarthropathy, 781 Oxcarbazepine, in diabetic neuropathy, 765 Oxycodone, in diabetic neuropathy, 766 P Pancreas transplant, in diabetic neuropathy, Pedorthist, certified, role in diabetic foot care, 718 Peripheral nerve release, in diabetic neuropathy, 769 Peripheral neuropathy, in diabetes, Peripheral vascular disease, in diabetes, Phenytoin, in diabetic neuropathy, Pioglitazone, 710 Pramlintide, 712 Pregabalin, in diabetic neuropathy, 765 Prosthesis, partial foot, 728 R Ray amputations, Retinopathy, diabetic. See Diabetic retinopathy. Ring external fixation, in Charcot arthropathy, morbid obesity and, 843 osteomyslitis and, 842 patient selection for, surgical candidates for, surgical technique for, 842, 843, 844 treatment examples of, 841, , 845 treatment strategy for, Rocker soles, double, 731 heel-to-toe, 730, 731 mild, 730, 731 negative heel, 731 severe angle, 731 terminology associated with, 730 toe-only, types of, , 731, 740 S Serotonin reuptake inhibitors, selective, in diabetic neuropathy, 766 Shoe(s), custom-made, 720 depth of, 721 fitting of, for diabetic patients, objectives of, half-shoes, 738 in-depth, 720 modification of, 720, modifications of, extended shank, flares as, 732 relasting as, 732 rocker soles as. See Rocker soles. selection of, 721 shape of, and last, 721, 722 Silver, in wound healing, 749 Substance P, inhibitors of, in diabetic neuropathy, 767 Sulfonylurea, 711 Syme amputation, 793, T Thiazolidenediones, 711 Toes, amputations of, 793, 794 Topiramate, in diabetic neuropathy, 766 Tramadol, in diabetic neuropathy, 766 Transmetatarsal amputation, 793, Transtibial amputations, 793,

5 INDEX 869 U Ulcers, diabetic foot. See Diabetic foot ulcers. V Vacuum-assisted wound closure, W Wound healing, delayed, in diabetes, impediments to, 745, inflammatory phase of, 746 macrophages in, 746 re-epithelialization in, 746 stages of, wound contraction in, 746 Wound healing agents, Wound therapy, negative pressure, 737 Wounds, healing, off-loading of, 738

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