Pump Therapy - Simple, Proven, and Well Accepted
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1 Pump Therapy - Simple, Proven, and Well Accepted Innovating for life.
2 Pump therapy is simple for providers and patients Healthcare Providers Simple outpatient procedure: Low burden and cost to transition patients from MDI Streamlined protocol: Easy candidate selection, initiation, and insulin titration Improved patient outcomes: 3,5, ,8 Lowers A1C and reduces hypoglycemia for better patient management Patients Simple training: Minimal time and knowledge needed to transition to pump therapy Easy to use pump features: Automatic basal and easy bolusing reduces therapy burden Freedom from injections: Simple infusion set changes every 2-3 days Small and light weight: Conveniently fits into lifestyle and insulin is always accessible Medtronic provides support to providers and patients to simplify pump therapy Medtronic offers the following services to HCPs and patients: HCP Pump therapy education and ongoing support Patient Pump therapy demonstration Patient Pump training and troubleshooting Ongoing support to patients to ensure positive clinical outcomes Local Support
3 proven A clinically - safe, effective, and reliable therapy for type 1 diabetes SAFE: 1-3,8 Reduces Hypoglycemia and Diabetic Ketoacidosis 4-7 Pump therapy reduces hypoglycemia in comparison to MDI RUDOLPH: 73.8% reduction in severe hypoglycemia while also reducing A1C BODE: Six fold reduction in severe hypoglycemia during the first year that was sustained for years 2, 3, and 4 BOLAND: 50% reduction in severe hypoglycemia after 12 months of therapy EFFECTIVE: 3,5,8-13 8,14 Reduces A1C and Glycemic Variability A1C (%) 8 A1C / values are mean ± SEM 5 Nations Trial: Randomized control trial conducted in 11 European centers 272 type 1 patients were transitioned to either MDI or pump therapy for 8 months, then crossover Pump therapy resulted in a 0.85% A1C reduction while also reducing glucose fluctuation by 0.8 mmol/l (15mg/dL) RELIABLE: A meta-analysis of 1,547 patients across 52 studies demonstrated pump therapy to consistently reduce A1C 15 in comparison to MDI A1C Duration Brutomesso (n=138) 89 months Bell (n=58) 36 months 3,5,9-13 Reduction in A1C Rudolph (n=107) 36 months Chantelau (n=116) 54 months Boland (n=25) 12 months Pump Therapy MDI Maniatis (n=56) 12 months Litton (n=9) 13 months 7 clinical articles representing 509 patients concluded pump therapy reduces A1C in comparison to MDI 3,5,9-13
4 well accepted Pump Therapy is around the World and in India Globally >800,000 patients use pump therapy to manage their diabetes Physicians from over countries prescribe pump therapy with confidence In India >5,000 patients use pump therapy to manage their diabetes 17 >250 physicians prescribe pump therapy 17 Pump Therapy Approved by various International Regulatory Bodies Health Canada Health Canada, Canada FDA, USA TGA, Australia Health Safety Regulation PMDA, Japan SFDA, China CE, European Union MHRA, UK Simple, Proven and Well Accepted
5 Insulin Pump Therapy: The India Experience Physician Real Life Experiences Type 1 Adult: I am very pleased that we were able to solve the problem of the nocturnal hypoglycemia, which was the complaint in her pre pump visits Dr. S. K. Wangnoo Chief Endocrinologist, Apollo Hospital, Delhi. Type 1 Pediatric: Due to the unpredictability of long acting insulin it was very difficult to obtain normal blood sugar levels with injections. The Insulin Pump delivers fastacting insulin only, just like the pancreas. We are pleased with the clinical outcomes of this case the progress Segar has made. Dr. Sanjeev R. Phatak & Dr. P. S. Iyengar Sterling Hospital, Ahmedabad. Type 1 Pregnant Adult: Thanks to Insulin Pump Therapy, this patient s glucose levels improved and her complications have settled down. It is indeed a boon for such patients, helping them to achieve and maintain a good glycemic control, specially in pregnancy when blood glucose levels can be ex tremely dangerous, both for the mother and growing foetus. Dr. Rema Mohan, Dr. V. Mohan, Dr. Shalini B. & Dr. N. G. Sastry Dr. Mohan s Diabetes Speciality Centre, Chennai. TM Minimed Veo Insulin Pump Patient Testimonials I am feeling better in general because now I control my diabetes rather than diabetes control my life. Female, 28 years old Type 1 diabetes, Delhi. Our son is feeling much better now that he is on an Insulin Pump. The Pump is easy to program. We are feeling less worried that our son will have a severe low blood sugar in the middle of the night. Parents, male 12 years old Ahmedabad. 98% of patients continue pump therapy long term 16 Prescribe pump therapy with confidence for your type 1 patients.
6 References: 1. Rudolph JW, Hirsch IB. Endocrine Practice. 2002; 8: Bode, B W, Steed RD, Davidson PC. Diabetes Care. 1996;19: Boland EA, Grey M, Oesterle A, et al. Diabetes Care. 1999; 22: Plotnick LP, et al. Diabetes Care. 2003; 26: Bruttomesso D. Diabet Med. 2002; 19: Linkeschova M, et al. Diabetes 2002; 19: Steindel BS, et al. Diabetes Res Clin Pract. 1995; 27: Hoogma RP, et al. Diabetic Med. 2005; 23: Bell DSH, et al. Endocr Pract. 2000; 6: Rudolph DS, et al. Endocr Pract. 2002; 8: Chantelau E, et al. Diabetologia. 1989;32: Maniatis AK, et al. Pediatrics. 2001;107: Litton J, et al. J Pediatr. 2002;141: Lepore, et al. Diabetes. 2000; 49: Weissberg Benchell J, et al. Diabetes Care. 2003; 26: Bode BW, Tamborlane WV, Davidson PC. Postgraduate Medicine. 2002; 111: Medtronic Internal data. For the use of a registered medical practitioner / hospital / laboratory only India Medtronic Pvt. Ltd Solitaire Corporate Park, Bldg. 12, 4th Floor, Andheri-Ghatkopar Link Road, Andheri (E), Mumbai Tel: /01/02/03 Fax: rs.indiadiabeteshelpdesk@medtronic.com INDCSII-HCP EN@2013 Medtronic, MiniMed Inc. All rights reserved.
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