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1 SOURCE: Over four years, drug prices skyrockected Top 100 Price Increases Unit Basic Category Simple Name Category Description ANTIBIOTIC EACH ANTIBIOTIC TETRACYCLINE HIGH CHOLESTEROL EACH HEART/STROKE/BLOOD PRESSURE NIACIN ER ANTIBIOTIC EACH ANTIBIOTIC DOXYCYCLINE HYCLATE ANTI-INFLAMMATORY EACH PAIN NAPROXEN SODIUM EACH OTHER DUEXIS ARTHRITIS EYE DROPS ML EYE DROPS FLUOROMETHOLONE HIGH BLOOD PRESSURE EACH HEART/STROKE/BLOOD PRESSURE DOXAZOSIN SKIN/ACNE GM SKIN ERYTHROMYCIN GM SKIN CARAC CREAM SKIN EACH HEART/STROKE/BLOOD PRESSURE TENORMIN HEART EACH PAIN MEPHYTON OVERDOSE MENTAL HEALTH/PAIN EACH MENTAL HEALTH CARBAMAZEPINE SKIN/ACNE GM SKIN TRETINOIN ANTI-INFLAMMATORY ML PAIN KETOROLAC EACH OTHER MESTINON MUSCLE ML EYE DROPS FML FORTE EYE DROPS MENTAL HEALTH/INSOMNIA ML MENTAL HEALTH PHENOBARBITAL GM SKIN HALOG CREAM SKIN EACH CANCER LEUKERAN CANCER COLD SORES ML SKIN ACYCLOVIR EACH OTHER TIROSINT THYROID HIGH CHOLESTEROL EACH HEART/STROKE/BLOOD PRESSURE PRAVASTATIN ANTIBIOTIC ML ANTIBIOTIC CEPHALEXIN CANCER/ARTHRITIS EACH CANCER METHOTREXATE
2 ML OTHER ALINIA DIARRHEA ML ASTHMA/ALLERGY ZUTRIPRO SOLUTION ALLERGY ML PAIN DEMEROL PAIN ML SKIN EXELDERM SKIN ML ANTIBIOTIC PRIMSOL ANTIBIOTIC ML PAIN RELISTOR OPIOD-INDUCED CONSTIPATION ANTIBIOTIC GM ANTIBIOTIC CLINDAMYCIN EACH OTHER HORIZANT ER RESTLESS LEG SYNDROME EYE DROPS ML EYE DROPS SULFACETAMIDE GM SKIN SUMADAN SKIN/ACNE EACH MENTAL HEALTH FANAPT MENTAL HEALTH DAILY ASTHMA/ALLERGY ADVAIR ASTHMA EYE DROPS ML EYE DROPS ATROPINE EA ASTHMA/ALLERGY EPIPEN ALLERGY ML DIABETES APIDRA DIABETES ANTIBIOTIC EACH ANTIBIOTIC CEFUROXIME AXETIL EACH PAIN ZIPSOR PAIN EACH PAIN NAPRELAN CR ANTI-INFLAMMATORY EACH MENOPAUSE VAGIFEM MENOPAUSE MUSCLE EACH OTHER PYRIDOSTIGMINE BR EACH PAIN GRALISE PAIN VITAMIN/SUPPLEMENT EACH OTHER BACMIN EACH MENTAL HEALTH EMSAM MENTAL HEALTH SKIN/ITCH GM SKIN FLUOCINONIDE GM SKIN ALTABAX SKIN EACH OTHER OXYTROL URINARY MENTAL HEALTH/ANXIETY EACH MENTAL HEALTH HYDROXYZINE GM HEART/STROKE/BLOOD PRESSURE NITROLINGUAL HEART HEART EACH HEART/STROKE/BLOOD PRESSURE VERAPAMIL
3 EACH OTHER CIALIS ERECTILE DYSFUNCTION EACH MENTAL HEALTH ONFI MENTAL HEALTH EACH PAIN CAMBIA ANTI-INFLAMMATORY EACH MENOPAUSE COMBIPATCH MENOPAUSE ML EYE DROPS AZOPT EYE DROPS ML DIABETES LEVEMIR DIABETES GM EYE DROPS TOBREX EYE DROPS GM SKIN ATRALIN SKIN/ACNE EACH OTHER STAXYN ERECTILE DYSFUNCTION EACH MENTAL HEALTH SAVELLA TITRATION PACK MENTAL HEALTH EACH OTHER FELBATOL EPILEPSY EACH OTHER RAPAMUNE KIDNEY TRANSPLANT ML OTHER FORTEO PEN OSTEOPROROSIS ML OTHER APLISOL TUBERCULOSIS EACH MENTAL HEALTH FAZACLO MENTAL HEALTH EACH OTHER BANZEL EPILEPSY EACH HEART/STROKE/BLOOD PRESSURE LIPOFEN HIGH CHOLESTEROL HEARTBURN ML HEART/STROKE/BLOOD PRESSURE CIMETIDINE EACH MENTAL HEALTH EXELON MENTAL HEALTH/ALZHEIMER'S EACH MENOPAUSE FEMRING MENOPAUSE ML DIABETES LANTUS DIABETES EACH PAIN NUCYNTA PAIN ML EYE DROPS VEXOL EYE DROPS EA OTHER HUMIRA ARTHRITIS/CHOHN'S EA HEART/STROKE/BLOOD PRESSURE EXFORGE HTC BLOOD PRESSURE DIABETES EACH DIABETES GLYBURIDE MICRO EA HEART/STROKE/BLOOD PRESSURE LESCOL XL CHOLESTEROL EA OTHER AMRIX ER MUSCLE EACH MENTAL HEALTH LATUDA MENTAL HEALTH
4 EA HEART/STROKE/BLOOD PRESSURE EDARBI BLOOD PRESSURE ML DIABETES HUMULIN DIABETES EACH OTHER ENBREL PLAQUE PSORIASIS EA HEART/STROKE/BLOOD PRESSURE EDARBYCLOR BLOOD PRESSURE EA MENTAL HEALTH KAPVAY ER MENTAL HEALTH EA MENTAL HEALTH RITALIN LA MENTAL HEALTH ML DIABETES HUMALOG CARTRIDGE DIABETES ML EYE DROPS PATANOL EYE DROPS EA MENOPAUSE VIVELLE-DOT MENOPAUSE ML DIABETES BYETTA DIABETES ANTIBIOTIC EACH ANTIBIOTIC VANCOMYCIN ANTIBIOTIC ML ANTIBIOTIC CEFDINIR EA HEART/STROKE/BLOOD PRESSURE AGGRENOX STROKE ML DIABETES NOVOLOG DIABETES EACH PAIN LYRICA PAIN ML OTHER AXIRON HORMONE KIDNEY DISEASE/DIALYSIS ML OTHER LEVOCARNITINE EACH CANCER GLEEVEC CANCER
5 costs/ % Increase Per Unit Price 2012 Per Unit Price 2016 Type 12,100 $0.07 $8.54 Generic (On the market since 1978) 4,149 $0.06 $2.42 Generic 1,670 $0.06 $1.00 Generic 1,381 $0.09 $1.26 Generic 1,171 $1.73 $22.02 Brand 920 $1.20 $12.22 Generic 880 $0.05 $0.46 Generic 685 $0.37 $2.89 Generic 684 $10.22 $80.16 Brand 664 $1.53 $11.67 Brand 579 $8.40 $57.07 Brand 577 $0.06 $0.41 Generic 538 $0.70 $4.45 Generic 509 $0.68 $4.13 Generic 419 $4.23 $21.99 Brand 394 $4.68 $23.09 Brand 393 $0.03 $0.13 Generic 382 $2.78 $13.39 Brand 335 $4.48 $19.49 Brand 323 $0.15 $0.65 Generic 314 $0.93 $3.85 Brand 297 $0.07 $0.26 Generic 287 $0.04 $0.15 Generic 284 $0.34 $1.29 Generic
6 274 $1.40 $5.23 Brand 265 $0.38 $1.39 Brand 253 $0.87 $3.07 Brand 248 $2.72 $9.48 Brand 238 $0.43 $1.43 Brand 234 $47.73 $ Brand 233 $0.53 $1.77 Generic 215 $3.37 $10.63 Brand 194 $1.03 $3.03 Generic 191 $0.40 $1.18 Brand 188 $10.22 $29.43 Brand 187 $3.07 $8.82 Brand 187 $1.74 $4.98 Generic 173 $ $ Brand 171 $9.12 $24.74 Brand 171 $0.38 $1.03 Generic 166 $2.82 $7.51 Brand 163 $7.72 $20.31 Brand 155 $8.03 $20.47 Brand 153 $0.23 $0.58 Generic 152 $2.54 $6.39 Brand 152 $0.27 $0.68 Generic 149 $19.48 $48.58 Brand 148 $0.77 $1.90 Generic 143 $5.57 $13.53 Brand 141 $27.15 $65.37 Brand 141 $0.22 $0.54 Generic 138 $22.67 $54.00 Brand 134 $1.34 $3.14 Generic
7 131 $3.70 $8.54 Brand 127 $6.20 $14.07 Brand 125 $22.21 $49.99 Brand 124 $7.84 $17.54 Brand 123 $10.96 $24.49 Brand 121 $11.80 $26.07 Brand 117 $24.54 $53.27 Brand 116 $5.56 $12.02 Brand 115 $12.65 $27.17 Brand 114 $2.20 $4.70 Brand 114 $2.59 $5.56 Brand 114 $5.75 $12.28 Brand 112 $ $1, Brand 109 $30.92 $64.54 Brand 108 $7.36 $15.33 Brand 107 $1.23 $2.53 Brand 104 $1.67 $3.39 Brand 102 $0.03 $0.07 Generic 101 $8.75 $17.57 Brand 100 $ $ Brand 100 $11.98 $23.93 Brand 99 $4.65 $9.24 Brand 99 $8.38 $16.70 Brand 98 $1, $1, Brand 97 $4.09 $8.05 Brand 97 $0.03 $0.05 Generic 96 $4.66 $9.13 Brand 96 $14.98 $29.38 Brand 96 $15.11 $29.56 Brand
8 95 $2.60 $5.08 Brand 95 $34.39 $66.96 Brand 94 $ $ Brand 92 $2.72 $5.23 Brand 92 $2.82 $5.42 Brand 91 $4.54 $8.66 Brand 91 $15.90 $30.31 Brand 91 $23.99 $45.75 Brand 90 $7.72 $14.69 Brand 90 $ $ Brand 90 $5.05 $9.63 Generic 90 $0.21 $0.40 Generic 89 $3.97 $7.48 Brand 89 $16.15 $30.56 Brand 88 $3.00 $5.64 Brand 87 $3.30 $6.18 Brand 84 $0.16 $0.29 Generic 71 $52.88 $90.35 Brand
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