Evidence Process for CVA-TIA Guideline Research 5/29/2018
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1 58 Potentially relevant guidelines identified in various resources* Searches done Apr. 5-10, guidelines evaluated using AGREE II 13 practice-based guidelines included 8 selected as practice-based 4 failed AGREE II and included as practice-based 7 guidelines failed AGREE II 31 guidelines excluded Exclusion Criteria: Non-English language Pediatrics Age of Publication Ex-U.S. focus Little or no discussion of advanced imaging Recommendations unclear 14 guidelines passed AGREE II and included as evidencebased
2 Ovid MedLine Search 1 5/1/ (mechanical thrombectomy or tpa or tissue plasminogen activator).mp. 2. exp thrombectomy/ or mechanical thrombolysis/ or Tissue Plasminogen Activator/ 3. 1 or 2 4. (systemati* review or (randomiz* control* or RCT or randomized controlled trial*) or guidance or guideline or recommendation or (meta analysis or metaanalysis or meta-analysis)).mp and 4 6. limit 5 to (english language and humans and yr="2012 -Current" and "all adult (19 plus years)") 553 results/ 547 results after duplicates removed 9 excluded 24 Abstracts screened randomized controlled trials, systematic reviews, and various other types of studies 15 included in evidence
3 Ovid MedLine Search 2 5/1/ (systemati* review or (randomiz* control* or RCT or randomized controlled trial*) or guidance or guideline or recommendation or (meta analysis or metaanalysis or meta-analysis)).mp. 2. ((Sinus or (cerebr* and (ven* or vein))) and thrombos*).mp. 3. exp Sinus Thrombosis, Intracranial/ 4. ((Cerebral or cavernous or sagittal or transverse or cortical) and (ven* sinus or vein) and thrombos*).mp and (2 or 3 or 4) 78 results 0 Excluded 2 Abstracts screened 2 meta-analyses 2 included in evidence
4 Ovid MedLine Search 3 5/1/ exp STROKE/ or (stroke or transient ischemic attack or TIA or CVA or cerebral vascular accident).mp. 2. exp Diagnostic Imaging/ or Nuclear Medicine/ or Tomography, X-Ray Computed/ or Magnetic Resonance Imaging/ or (neuroimaging or compute* tomography or CTA or MRI or MRA or magnetic resonance or imaging or scintigraphy or HDP or MDP or 99mTc or SPECT or nuclear medicine or Ga- 67 or Tc-99m or CT or DECT or PET).mp. 3. (systemati* review or (randomiz* control* or RCT or randomized controlled trial*) or guidance or guideline or recommendation or (meta analysis or metaanalysis or meta-analysis)).mp and 2 and 3 5. limit 4 to (english language and humans and yr="2007 -Current" and "all adult (19 plus years)") 2190 results, 2008 results after duplicates removed 9 Excluded 17 Abstracts screened Randomized controlled trials, systematic reviews, metaanalyses, various other studies 8 included in evidence
5 Ovid MedLine Search 4 5/11/ (cryptogenic or ((unknown or undetermined) adj1 (etiology or origin or source))).mp. 2. (exp STROKE/ or stroke.mp. or CVA.mp. or (brain or cerebral or cerebrovascular).mp.) and (stroke or infarct or vascular accident).mp. 3. embolic stroke of undetermined source.mp. 4. (work up or work-up or work up or management).mp. 5. Practice Patterns, Physicians'/ or practice pattern*.mp. 6. ((1 and 2) or 3) and (4 or 5) 7. limit 6 to (english language and humans and yr="2013 -Current" and "all adult (19 plus years)") 8. (review or meta-analysis or metaanalysis or meta analysis).mp and 8 10 results, no duplicates, 9 results after duplicates from all picos removed 0 Abstracts screened
6 Ovid MedLine Search 5 5/11/ (systemati* review or (meta analysis or metaanalysis or meta-analysis)).mp. 2. ((CNS or central nervous system or cerebral or granulomatous) adj2 (vasculitis or angiitis or arteritis)).mp. 3. exp Vasculitis, Central Nervous System/ 4. 1 and (2 or 3) 5. limit 4 to (english language and humans and "all adult (19 plus years)") 18 results 0 Abstracts screened
7 Ovid MedLine Search 6 5/11/ ((brain or cerebral or cerebrovascular).mp.) and ((exp STROKE/) or (stroke or infarct or vascular accident).mp.) 2. (follow up or follow-up or followup or aftercare or after care) 3. (systemati* review or (meta analysis or metaanalysis or meta-analysis)).mp 4. 1 and 2 and 3 5. limit 4 to (english language and humans and "all adult (19 plus years)") 115 results, 113 after dupes removed, 83 after dupes from all searches removed 1 Excluded 1 Abstract screened 1 systematic review 0 Included in evidence
8 Ovid MedLine Search 7 5/11/ ASYMPTOMATIC DISEASES/ or asymptomatic.mp. or silent.mp. or presymtomatic.mp. or presymptomatic.mp. 2. Carotid Stenosis/ or exp Cerebrovascular Disorders/ or Carotid Stenos*.mp. or (cerebrovascular and (disorder or disease)).mp. or Carotid occlusion.mp. or Carotid disease.mp. or cervical bruit.mp. 3. (screening or ultrasound or ultrasonography).mp. or exp ultrasonography/ or exp Diagnostic Imaging/ or Nuclear Medicine/ or Tomography, X-Ray Computed/ or Magnetic Resonance Imaging/ or (compute* tomography or CTA or MRI or MRA or magnetic resonance or imaging or scintigraphy or HDP or MDP or 99mTc or SPECT or nuclear medicine or Ga-67 or Tc-99m or CT or DECT or PET).mp. 4. (case adj2 (report or reports or study or studies)).mp. 5. (1 and 2 and 3) not 4 6. limit 5 to (english language and humans and yr="2016 -Current" and "all adult (19 plus years)") 397 results, 382 after duplicates removed, 365 after dupes from all picos removed 1 Excluded 6 Abstracts screened 6 Observational studies 5 Included in evidence
9 Ovid MedLine Search 8 5/14/ Decision Support Techniques/ or (clinical predict* or ABCD or ABCD2 or ABCD2-I or ABCD3 or ABCD3-I).mp. 2. exp Diagnostic Imaging/ or Nuclear Medicine/ or Tomography, X-Ray Computed/ or Magnetic Resonance Imaging/ or (neuroimaging or compute* tomography or CTA or MRI or MRA or magnetic resonance or imaging or scintigraphy or HDP or MDP or 99mTc or SPECT or nuclear medicine or Ga- 67 or Tc-99m or CT or DECT or PET).mp. 3. Ischemic Attack, Transient/ or TIA.mp. or transient ischemic attack.mp and 2 and 3 5. limit 4 to (english language and humans and yr="2015 -Current" and "all adult (19 plus years)") 30 results, after duplicates removed 29 results, after duplicates from all PICOs removed, 25 results 1 Excluded 7 Abstracts screened 7 Observational studies 6 Included in evidence
10 Search 9 5/14- Hand Search of bibliographies 0 Excluded 17 articles selected 6 randomized controlled trials, 3 systematic reviews, various other types of studies 17 Included in evidence
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