Specialist palliative care for patients with heart failure. Dr Katie Taylor Consultant in Palliative Medicine
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1 Specialist palliative care for patients with heart failure Dr Katie Taylor Consultant in Palliative Medicine
2 Objectives Identify which patients to refer to hospice Review symptom management Think about rationalising medications Be aware of services which the hospice could provide
3 Questions to consider What are the barriers to providing good end of life care for patients with heart failure? What works well? What is more challenging? Are there specific patient examples that you can share?
4 Some heart failure statistics 500,000 people in UK 76y - average age at diagnosis 30-40% die within 1 year Costs NHS million/year 2% of all NHS inpatient bed days 5% of all emergency admissions Cardiovascular disease statistics 2014 BHF
5 More statistics Prevalence of heart failure rising Ageing population Improved survival with IHD Improved heart failure treatment 6 month mortality rate falling: 26% 1995 to 14% 2005 Hospital admissions predicted to rise by 50% over next 25 years
6 NYHA classification
7 Morbidity Significant symptom burden Patients have poor understanding of illness progression Less likely to plan for death & dying 83-95% die in acute or elderly care hospital bed 1% die in hospice
8 When to refer to hospice The typical disease trajectories identified in patients with different diseases.
9 Integrated palliative/cardiology services Which deterioration is the terminal one? Change of emphasis from active to palliative management difficult Indicators of poor prognosis provide a trigger for conversations about future plans what would you want to do if things get worse Heart failure MDT
10 Indicators of Poor Prognosis Previous admissions with worsening heart failure No identifiable reversible precipitant Receiving optimum tolerated conventional drugs Worsening renal function and low sodium Failure to respond within 2-3 days to appropriate change in diuretic or vasodilator drugs Sustained hypotension Up to 50% patients with heart failure die suddenly
11 Specific clinical indicators for heart failure: CHF NYHA Stage 3 or 4 Patient thought to be in last year of life Repeated hospital admissions with heart failure symptoms Physical or psychological symptoms despite optimal tolerated therapy
12 Roles of specialist palliative care
13 Symptoms Anderson et al (2001) Pall Med 15(4):
14 SOB Non-pharmacological Relaxation/distraction Breathing retraining Lifestyle changes Hand-held fan Complementary tx Exercise group Drugs Oramorph 2.5mg 4hrly Lorazepam 0.5mg prn GTN spray
15 Fatigue Exclude reversible causes Hb, TFTs, U&E, calcium, magnesium Review medication Beta blockers, ACE Screen for anxiety/depression Pace activity Graded exercise Dietary advice
16 Polypharmacy Chronic use of >4 medications 36% patients over 75 take >4 drugs 50% drugs are not taken as prescribed Drug interactions Adverse reactions Pill burden
17 ADRs
18 Rationalising medications Which medications are providing immediate symptom benefit? Which medications might produce rebound symptoms/rapid deterioration if stopped?
19 Consider 1 st Consider 2 nd Consider 3 rd Discontinue drugs with only long term benefit (mortality) Statins Digoxin (in sinus rhythm) Weigh up advantages/disadvantages of continuing drugs with medium term benefit (morbidity/mortality) ACE/ARB Beta blocker Spironolactone Drugs for co-morbidities Hypoglycaemics Antihypertensives Thyroxine Warfarin Continue drugs for short term benefit (morbidity) Loop & thiazide diuretics Digoxin/beta-blockers (in AF) Anti anginals
20 Subcutaneous furosemide Patient selection Advanced CHF Wish to avoid hospital Need parenteral diuretics Indications Symptom management End of life Unresponsive to high dose oral diuretics PPC home/hospice Poor venous access
21 Paracentesis Patients with right heart failure Ascites persists despite aggressive diuretic tx Symptomatic 4-6 litre slow paracentesis Over few days
22 Input from palliative care Hospital Hospice day service Hospice in the home Hospice inpatient unit Counselling Carer support
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