LIBiol Fresh Cells /23

Transcription

1 LIBiol Fresh Cells /23

2 Mild, selective enzymatic extraction Cellular suspension Natural microcapsules LIBiol Fresh Cells /23

3 Enzymatic extraction Primary Cell wall Secondary Cell wall Cell membrane LIBiol Fresh Cells /23

4 Mitochondria Membrane Central vacuole Vitamins Organic components Mineral salts Nucleus Chloroplasts LIBiol Fresh Cells /23

5 Claims Visualize nature s smallest vessel Preservation of its structure Natural protection of the cell s molecular load Benefits Use of all the cell components Very rich in mineral salts, vitamins and oligoelements Enzymatic inhibition LIBiol Fresh Cells /23

6 Strawberry : Vitamin C, Ca++, Mg++ Depurative, Stimulate tired skin Kiwi : Very rich in Vitamin C Antioxidant & enzymatic inhibitor Protector for young skin Carrot : ß-caroten, Potassium, Sodium Heal & murture the skin Prepare to sun exposure. Mango : Pro vitamin A & Vitamin C Fe++, Mg++ To fight skin ageing Pumpkin : ß-caroten, Mg++, Zn++ Antioxidant & soothing properties Ideal for sun-burns or irritated skin LIBiol Fresh Cells /23

7 MINERAL SALTS DOSAGE Flame Photometry Atomic Absorption Photometry RADICAL SCAVENGER EFFECT Superoxide Anion : Reduction of the Nitro-blue-tetrazolium to Formazan blue. Radical DPPH : Reduction ratio of the DPPH radical Hydroxyl Anion : Reduction ratio of DMSO to formaldehyde ENZYMATIC INHIBITION Hyaluronidase inhibition Tyrosinase inhibition LIBiol Fresh Cells /23

8 Carrot Strawberry Kiwi Mango Pumpkin Calcium 1,46 1,05 0,96 0,42 1,96 Iron 0,28 0,33 0,39 0,27 0,44 Magnesium 2,21 2,89 2,12 1,63 3,2 Potassium 65,16 44,26 62,3 31,79 68,05 Zinc 0,03 0,02 0,009 0,04 0,05 Results are expressed in mg for 100 g of product LIBiol Fresh Cells /23

9 Tyrosinase inhibition Hyaluronidase inhibition 42,7% 37,3% 31,4% 36% Product tested at 20% 32,2% 31,3% Inhibition % Inhibition % Fresh Cells Pumpkin Fresh Cells Mango Fresh Cells Kiwi Fresh Cells Strawberry Fresh Cells Mango Fresh Cells Pumpkin In Vitro test : inhibition of tyrosinase is shown for all three references, ranking between 31% and 42%. In Vitro test : Hyaluronidase is significantly inhibited for the references presented (31 to 36%), thus protecting the water-reservoir molecules in the skin hyaluronic acid. LIBiol Fresh Cells /23

10 R-O-R : Molecular oxygen UV, Pollution, Tobacco O 2 - : Superoxide anion Peroxide The cellular suspensions have shown significant free-radical scavenging effects on hydroxyl, superoxide and DDPH radicals. This inhibiting activity makes the Fresh Cells an ideal ingredient for all antistress, anti-age, or protective cosmetic products. OH - : Hydroxyl anion Destruction of biological molecules (Fatty acids, Proteins, Sugar ) R R-OO Infernal cycle LIBiol Fresh Cells /23

11 Reduction ratio of the DPPH Radical, measured by spectrophotometry at 517nm Scavenger effect on DPPH 16,9% 16,4% Product tested at 10% Inhibition % 8,5% Fresh Cells Carrot Fresh Cells Kiwi Fresh Cells Pumpkin DPPH = 1,1 Diphenyl 2 Picryl Hydrazyl LIBiol Fresh Cells /23

12 Reduction ratio of the Nitro-Blue tetrazolium to formazan blue measured by spectrophotometry at 517nm. Scavenger effect on superoxide anion 47,5% 61,9% Product tested at 10% Product tested at 1% 49,3% Inhibition % 12,40% 32,40% 17,90% Fresh Cells Kiwi Fresh Cells Carrot Fresh Cells Pumpkin Superoxide anion = O 2 - LIBiol Fresh Cells /23

13 Reduction ratio of the DMSO to Formaldehyde measured by spectrophotometry Scavenger effect on hydroxyl anion 53,4% 37,4% Inhibition % 22,3% Fresh Cells Kiwi Fresh Cells Carrot Fresh Cells Pumpkin Hydroxyl anion = OH - LIBiol Fresh Cells /23

14 Easy to formulate Add at the end of the emulsification process Stable in complex formulation 1 year of stability LIBiol Fresh Cells /23

15 Strawberry Fresh Cell in a body milk Pumpkin Fresh Cell in a body milk LIBiol Fresh Cells /23

16 Faculty of Chatenay Malabry (Paris) Cofocal microscopy CNRS Vegetal Physiology (Gif /Yvette) Analysis of the cell s structure LIBiol Fresh Cells /23

17 LIBiol Fresh Cells /23

18 LIBiol Fresh Cells /23

19 Davines (Italy) Bio O Invisible INVISIBLE IMPACT, ANTI-FREE RADICAL ACTION, VOLUME, COMPLETE HYDRATION, RE-MINERALIZING EFFECT. FOR FINE AND DELICATE HAIR. WITH PUMPKIN FRESH CELLS AND WHEAT PROTEINS Darphin (France) Hydraskin Range MANGO FRESH CELLS KIWI FRESH CELLS Quimibel (Spain) MANGO FRESH CELLS KIWI FRESH CELLS Pacific (Korea) Functional cosmetic PUMPKIN FRESH CELLS, STRAWBERRY FRESH CELLS, CARROT FRESH CELLS, MANGO FRESH CELLS LIBiol Fresh Cells /23

20 Brume pour le Corps JB 1315/D Body Lotion JB1315/D Ingredients INCI DENOMINATION % W/W Function KIWI ORIGINAL EXTRACT ACTINIDIA CHINENSIS (KIWI) FRUIT WATER 97,2 Vegetal Water (1) KIWI FRESH CELLS (2) AQUA (AND) ACTINIDIA CHINENSIS (KIWI) FRUIT EXTRACT (AND) XANTHAN GUM 2 Active Ingredient GLYDANT PLUS LIQUID (3) YELLOW E102 (sol at 0,5%) (4) DMDM HYDANTOIN (AND) 0,3 Preservative IODOPROPYNYL BUTYLCARBAMATE CI Coloring agent FDC red 4 (sol at 0.1%) (4) CI ,06 Coloring agent GREEN E 102 / E 131 (sol at 0,1%) (4) PEMULEN TR2 (5) SODIUM HYDROXIDE (sol at 10%) Appearance : Green lotion CI 19140/CI / CI ,1 Coloring agent ACRYLATES/C10-30 ALKYL ACRYLATE CROSSPOLYMER 0,05 Gelifying agent SODIUM HYDROXIDE 0,06 Neutralizing agent 100 Aspect : Lotion verte Manufacturing Process : Mode opératoire : Spread the pemulen in the kiwi original Disperser le pemulen dans l extrait originel de extract. Add the coloring agents, meutralize. kiwi. Ajouter les colorants, neutraliser puis Then, under a soft stirring, add the glydant ajouter sous agitation lente le glydant et les and the kiwi fresh cells. cellules fraîches. (1) Gattefossé / (2) - Libiol / (3) - Lonza / (4) LCW / (5) Goodrich LIBiol Fresh Cells /23

21 Lait au Potiron MM7260 Pumpkin Milk MM7260 Ingredients INCI DENOMINATION % Function W/W Phase I PLUROL STEARIQUE (1) POLYGLYCERYL-6 DISTEARATE 5 PEG-Free O/W Emulsifier SOFTCUTOL O (1) ETHOXYDIGLYCOL OLEATE 5 Emollient LABRAFAC CC (1) CAPRYLIC/CAPRIC TRIGLYCERIDE 5 Emollient DOW CORNING 200 (100 CS) DIMETHICONE 4 Feeling agent (4) PHENONIP (3) PHENOXYETHANOL (AND) METHYLPARABEN (AND) BUTYLPARABEN (AND) ETHYLPARABEN (AND) PROPYLPARABEN 0,5 Preservative Phase II DEMINERALIZED WATER WATER 62,7 CARBOPOL ETD 2050 (6) CARBOMER 0,15 Gelifying agent RHODICARE S (2 % Sol.)(5) XANTHAN GUM 10 Gelifying agent Phase III SODIUM HYDROXIDE (10% Sol.) SODIUM HYDROXIDE 0.3 Neutralizing agent Phase IV DOW CORNING 1401 (4) CYCLOMETHICONE (AND) DIMETHICONOL 2 Feeling agent Phase V SIGN ESSENCE (1) 0,2 Perfume GLYDANT PLUS LIQUID (7) DMDM HYDANTOIN(AND) IODOPROPYNYL BUTYLCARBAMATE 0,15 Preservative PUMPKIN FRESH CELLS (2) AQUA (AND) CUCURBITA PEPO 5 Active Ingredient (PUMPKIN) FRUIT EXTRACT (AND) XANTHAN GUM 100 LIBiol Fresh Cells /23

22 Masque Capillaire MM7261 Capillary mask MM7261 Ingredients INCI DENOMINATION % Function W/W Phase I APIFIL (1) PEG-8 BEESWAX 2 O/W Emulsifier EMULCIRE 61 (1) CETYL ALCOHOL (AND) CETETH-20 1 O/W Emulsifier STEARYL ALCOHOL LABRAFAC CC (1) SOFTCUTOL B (1) SHEA BUTTER PHENONIP (3) (AND) STEARETH-20 STEARYL ALCOHOL CAPRYLIC/CAPRIC TRIGLYCERIDE ETHOXYDIGLYCOL BEHENATE SHEA BUTTER PHENOXYETHANOL (AND) METHYLPARABEN (AND) BUTYLPARABEN (AND) ETHYLPARABEN (AND) PROPYLPARABEN 1, ,5 Thickener Emollient Texture agent Emollient Preservative Phase II DEMINERALIZED WATER WATER 60,3 AVICEL RC (4) RHODICARE S (2% Sol.) (5) MICROCRYSTALLINE CELLULOSE (AND) CELLULOSE GUM XANTHAN GUM 1,5 20 Gelifying agent Gelifying agent Phase III SIGN ESSENCE (1) 0.2 Perfume MANGO FRESH CELLS (2) 5 Active Ingredient AQUA (AND) MANGIFERA INDICA (MANGO) FRUIT EXTRACT (AND) XANTHAN GUM LIBiol Fresh Cells /23

23 Lait corporel à la fraise JB 1306/A Strawberry body Milk JB 1306/A Ingredients INCI DENOMINATION % W/W Phase I TEFOSE 2561 (1) PEG-6 STEARATE (AND) CETETH-20 (AND) GLYCERYL STEARATE (AND) STEARETH-20 Function 5 Emulsifier MOD (1) OCTYL DODECYL MYRISTATE 8 Emollient VEGETOL CALENDULA CALENDULA OFFICINALIS FLOWER 2 Active ingredient WL1072 (1) EXTRACT CETYL ALCHOL CETYL ALCHOL 1 Texture agent DOW CORNING 200 (100CS) DIMETHICONE 3 Feeling agent (2) PHENONIP (3) PHENOXYETHANOL (AND) METHYLPARABEN (AND) BUTYLPARABEN (AND) ETHYLPARABEN (AND) PROPYLPARABEN 0,5 Preservative Phase II DEMINERALIZED WATER WATER 75 CARBOPOL 981 (4) CARBOMER 0,1 Gelifying agent Phase III SODIUM HYDROXIDE (sol at 10%) SODIUM HYDROXIDE 0,2 Neutralizing agent Phase IV STRAWBERRY FRESH CELLS (5) Appearance : Pink milk AQUA (AND) FRAGARIA VESCA (STRAWBERRY) FRUIT EXTRACT (AND) ASCORBIC ACID (AND) XANTHAN GUM Aspect : Lait Rosâtre 5 Active Ingredient 100 Manufacturing Process : Mode opératoire : Spread the Carbopol in water. Disperser le carbopol dans l eau. Under stirring, at 75 C, add I to II, then neutralize. Cool and at 35 C, under slow stirring add IV. Sous agitation, à 75 C, ajouter les composants de I à II, puis neutraliser. Laisser refroidir et vers 35 C, sous agitation modérée ajouter IV. (1) - Gattefossé / (2) Dow Corning / (3) - Nipa / (4) Goodrich / (5) LIBiol LIBiol Fresh Cells /23

24 Voile de Carotte JB 1320/A Complexion Enhancer JB 1320/A Ingredients INCI DENOMINATION % Function W/W Phase I DOW CORNING 345 (1) CYCLOMETHICONE 5 Feeling agent LABRAFIL ISOSTEARIQUE TRIISOSTEARIN PEG-6 ESTERS 1,5 Disperser (2) CAROTENE HUILEUX 1000 APRICOT KERNEL OIL PEG-6 ESTERS 1 Free radical (2) (AND) BETA-CAROTENE scavenger PARSOL MCX (3) OCTYL METHOXYCINNAMATE 1 UV filter PHENONIP (4) PHENOXYETHANOL (AND) 0,5 Preservative METHYLPARABEN (AND) BUTYLPARABEN (AND) ETHYLPARABEN (AND) PROPYLPARABEN Phase II DEMINERALIZED WATER WATER 75,4 PROPYLENE GLYCOL PROPYLENE GLYCOL 5 Moisturizer GLYCERIN GLYCERIN 3 Moisturizer ETD 2020 (5) ACRYLATES/C10-30 ALKYL ACRYLATE CROSSPOLYMER 0,5 Gelifying agent Phase III SODIUM HYDROXIDE (Sol at 10%) SODIUM HYDROXIDE 1 Neutralizing agent Phase IV BRUN COVASCOP W8772 (6) CI 77491/CI 77492/ CI ,4 Colouring agent FDC RED 4 (sol at 1%) (6) CI ,25 Colouring agent TIMIRON KARAT GOLD MICA (AND) TITANIUM DIOXIDE (AND) 0,25 Colouring agent MP24 (7) IRON OXIDES PERFUME SIGN ESSENCE 0,2 Perfume (2) CARROT FRESH CELLS (8) AQUA (AND) CAROTA (CARROT) 5 Active Ingredient FRUIT EXTRACT (AND) XANTHAN GUM 100 LIBiol Fresh Cells /23