Management of bone defects in total knee arthroplasty

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1 Chinese Journal of Tissue Engineering Research ( ) DOI: /j.issn ORCID: ( ) + + (1) (2) (3) ( ) AORI Engh Parks 3 AORI (Anderson Orthopaedic Research Institute) ( ) :R318 :A CNKIPubMed Medline Web of Science total knee arthroplasty total knee replacement revision total knee arthroplasty bone loss bone defect bone deficiency management 62 AORI ( ) ( ) (SATCM-2015-BZ115 SATCM-2015-BZ173) (2011B ) ([2011]157 )( YK2013B2N19 YN2015MS15) Management of bone defects in total knee arthroplasty Liang Hao-dong 1, Pan Jian-ke 2, Xie Hui 1, Huang He-tao 1, Han Yan-hong 1, Lin Jiong-tong 1, Liu Jun 2 ( 1 The Second School of Clinical Medicine, Guangzhou University of Chinese Medicine, Guangzhou , Guangdong Province, China; 2 Department of Orthopedics, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou , Guangdong Province, China) Liang Hao-dong, Master candidate, The Second School of Clinical Medicine, Guangzhou University of Chinese Medicine, Guangzhou , Guangdong Province, China Corresponding author: Liu Jun, Chief physician, Professor, Doctoral supervisor, Department of Orthopedics, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou , Guangdong Province, China 2414 : (2018)

2 Liang HD, Pan JK, Xie H, Huang HT, Han YH, Lin JT, Liu J. Management of bone defects in total knee arthroplasty. Zhongguo Zuzhi Gongcheng Yanjiu. 2018;22(15): DOI: /j.issn Abstract BACKGROUND: Bone defects are one of the most important challenges that surgeons have to manage in total knee arthroplasty. The reasonable treatment method can guarantee the effect of the repair operation. OBJECTIVE: To review the relevant literatures concerning bone defects treated by primary total knee arthroplasty and revision total knee arthroplasty, and to analyze the optimal managements for different types of bone defects. METHODS: Relevant literatures were identified in China National Knowledge Infrastructure, Wanfang data, Vip, PubMed, Medline, and Web of Science. The key words were total knee arthroplasty, total knee replacement, revision total knee arthroplasty, bone loss, bone defect, bone deficiency, management. The included studies were analyzed and summarized. RESULTS AND CONCLUSION: (1) Sixty-two studies regarding total knee arthroplasty for bone defects were included, without recognized standards on the type of bone defects. AORI is the most widely used classification for bone defects. (2) Pre-operated detailed evaluation including laboratory and radiographic examination, and accurate diagnosis are the key to success. (3) Management of bone defect was similar in tibia and femur, but there is still no standard classification and management of patellar bone defect. (4) Using stem fixation whenever a femoral or tibial component is revised can improve clinical outcome. (5) Through detailed evaluation, accurate diagnose and appropriate classification of bone defect, selection, according to the characteristics of different strategies, the age of the patient and the needs of life, can get a good clinical result. Subject headings: Arthroplasty, Replacement, Knee; Bone Defect; Tissue engineering Funding: the National Natural Science Foundation of China, No ; the Doctoral Fund of the Ministry of Education of China, No ; the Standardization Project of Traditional Chinese Medicine of the State Administration of Traditional Chinese Medicine of China, No. SATCM-2015-BZ115, SATCM-2015-BZ173; the Science and Technology Planning Project of Guangdong Province, No. 2011B ; the Project of Guangdong Provincial Department of Finance, No. [2011]157; the Science and Technology Research Project of Guangdong Provincial Hospital of Chinese Medicine, No. YK2013B2N19, YN2015MS15. 0 Introduction [1] 85% [2] [3] [4] [5] 1Data and methods CNKIPubMed Medline Web of Science total knee arthroplasty total knee replacement revision total knee arthroplasty bone loss bone defect bone deficiency management [1 12] [13 40] [41 62] 2 Results 2.1 C X CT X [6] X CT17% [7] CT + P.O. Box 10002, Shenyang

3 . [J] (15): DOI: /j.issn Rand Bargar Gross Engh Parks Rand 5 10 mm 3 [8] Bargar Gross 4 [9] Engh Parks 3 [10] AORI (Anderson Orthopaedic Research Institute) ( 1) Engh Ammeen [11] 2.3 AORI AORI ( <3 mm) Sugita [12] mm 6 6 [13] [14] 50 + [15] <5 mm < 50% Kharbanda [16] mm( 5 mm 6.5 mm) AORI B [17] [18] 16 Rand C [19] 2416 ISSN CN /R CODEN: ZLKHAH

4 Liang HD, Pan JK, Xie H, Huang HT, Han YH, Lin JT, Liu J. Management of bone defects in total knee arthroplasty. Zhongguo Zuzhi Gongcheng Yanjiu. 2018;22(15): DOI: /j.issn Rand Bargar Gross Engh Parks Engh Ammeen 5 10 mm 3 [8] 4 [9] 3 [10] AORI [11] A B C D 1 AORI A AORI B AORI C D AORI 2 3 [20] ( AORI ) [21] [22] [23] AORI 10 18Lee [24] Tsukada [25] [26-27] [28] Ritter [29] 57 9 mm 25% 7 [30] [31] Sculco [32] 5 25 mm [33] Heesterbeek [34] >1 mm >1 Kosse [35] (6.5 ) 2 21 Gofton [36] AORI B [37] [38] Clatworthy [39] % HSS % Backstein [40] P.O. Box 10002, Shenyang

5 . [J] (15): DOI: /j.issn [41] ( 2) Girerd [42] Brown [43] Fedorka [44] % Kamath [45] % 157 AORI % ( 3) [34 46] Nelson [47] (9% vs. 44%) Lachiewicz [48] 58 AORI B 30 mm 5 Nadorf [49] Berend [50] 5 20 mm 20 Beckmann [51] AORI (476 )(223 ) ( ) [52-56] Maheshwer [57] mm 35 KSS 3 <8 mm Seo [58] mm ( ) Gililland [59] 29/10 Nasser [60] [61] 3 Summary 2418 ISSN CN /R CODEN: ZLKHAH

6 Liang HD, Pan JK, Xie H, Huang HT, Han YH, Lin JT, Liu J. Management of bone defects in total knee arthroplasty. Zhongguo Zuzhi Gongcheng Yanjiu. 2018;22(15): DOI: /j.issn D [62] + AORI AORI AORI<5 mm mm / >10 mm AORI / / ( ) ( ) (SATCM-2015-BZ115 SATCM-2015-BZ173) (2011B ) ([2011]157 ) (YK2013B2N19 YN2015MS15) (PRISMA ) CNKI ( ) References [1] Glyn-Jones S, Palmer AJ, Agricola R, et al. Osteoarthritis. Lancet. 2015;386(9991): [2] Kurtz S, Ong K, Lau E, et al. Projections of primary and revision hip and knee arthroplasty in the United States from 2005 to J Bone Joint Surg Am. 2007;89(4): [3] Krackow KA, Mihalko WM. The effects of severe femoral bone loss on the flexion extension joint space in revision total knee arthroplasty: a cadaveric analysis and clinical consequences. Orthopedics. 2001;24(2): [4] Panegrossi G, Ceretti M, Papalia M, et al. Bone loss management in total knee revision surgery. Int Orthop. 2014;38(2): [5] Harris AI, Poddar S, Gitelis S, et al. Arthroplasty with a composite of an allograft and a prosthesis for knees with severe deficiency of bone. J Bone Joint Surg Am. 1995;77(3): [6] Mulhall KJ, Ghomrawi HM, Engh GA, et al. Radiographic prediction of intraoperative bone loss in knee arthroplasty revision. Clin Orthop Relat Res. 2006;446: [7] Reish TG, Clarke HD, Scuderi GR, et al. Use of multi-detector computed tomography for the detection of periprosthetic osteolysis in total knee arthroplasty. J Knee Surg.2006;19(4): [8] Rand JA. Bone deficiency in total knee arthroplasty. Use of metal wedge augmentation. Clin Orthop Relat Res. 1991;(271): [9] Bargar WL, Murzic WJ, Taylor JK, et al. Management of bone loss in revision total hip arthroplasty using custom cementless femoral components. J Arthroplasty. 1993;8(3): [10] Engh GA, Parks NL. The management of bone defects in revision total knee arthroplasty. Instr Course Lect. 1997;46: [11] Engh GA, Ammeen DJ. Classification and preoperative radiographic evaluation: knee. Orthop Clin North Am. 1998;29(2): [12] Sugita T, Aizawa T, Sasaki A, et al. Autologous morselised bone grafting for medial tibial defects in total knee arthroplasty. J Orthop Surg (Hong Kong). 2015;23(2): [13] Sugita T, Aizawa T, Miyatake N, et al. Preliminary results of managing large medial tibial defects in primary total knee arthroplasty: autogenous morcellised bone graft. Int Orthop. 2017;41(5): [14],,,. [J]., 2013,16(1): [15],,,. [J]., 2015,27(12): [16] Kharbanda Y, Sharma M. Autograft reconstructions for bone defects in primary total knee replacement in severe varus knees. Indian J Orthop. 2014;48(3): [17],,. [J]., 2012,16(18): [18],,,. RandC[J]. ( ), 2012,50(11): [19] Hoell S, Sieweke A, Gosheger G, et al. Eradication rates, risk factors, and implant selection in two-stage revision knee arthroplasty: a mid-term follow-up study. J Orthop Surg Res, 2016,11(1):93. [20] Vasso M, Beaufils P, Cerciello S, et al. Bone loss following knee arthroplasty: potential treatment options. Arch Orthop Trauma Surg, 2014,134(4): [21] Hockman DE, Ammeen D, Engh GA. Augments and allografts in revision total knee arthroplasty: usage and outcome using one modular revision prosthesis. J Arthroplasty.2005;20(1): [22] Frehill B, Crocombe AD, Agarwal Y, et al. Finite element assessment of block-augmented total knee arthroplasty. Comput Methods Biomech Biomed Engin. 2015;18(15): [23],,,. [J]., 2012,18(10): [24] Lee JK, Choi CH. Management of tibial bone defects with metal augmentation in primary total knee replacement: a minimum five-year review. J Bone Joint Surg Br. 2011;93(11): P.O. Box 10002, Shenyang

7 . [J] (15): DOI: /j.issn [25] Tsukada S, Wakui M, Matsueda M. Metal block augmentation for bone defects of the medial tibia during primary total knee arthroplasty. J Orthop Surg Res.2013;8:36. [26] Patel JV, Masonis JL, Guerin J, et al. The fate of augments to treat type-2 bone defects in revision knee arthroplasty. J Bone Joint Surg Br. 2004;86(2): [27] Stuchin SA. Allografting in total knee replacement arthroplasty. Semin Arthroplasty.1993;4(2): [28] Brooks PJ, Walker PS, Scott RD. Tibial component fixation in deficient tibial bone stock. Clin Orthop Relat Res. 1984;(184): [29] Ritter MA. Screw and cement fixation of large defects in total knee arthroplasty. J Arthroplasty.1986;1(2): [30] Ritter MA, Harty LD. Medial screws and cement: a possible mechanical augmentation in total knee arthroplasty. J Arthroplasty. 2004;19(5): [31] Ritter MA, Harty LD, Davis KE, et al. Simultaneous bilateral, staged bilateral, and unilateral total knee arthroplasty. A survival analysis. J Bone Joint Surg Am. 2003;85-A(8): [32] Sculco PK, Abdel MP, Hanssen AD, et al. The management of bone loss in revision total knee arthroplasty: rebuild, reinforce, and augment. Bone Joint J. 2016;98-B(1 Suppl A): [33] Panni AS, Vasso M, Cerciello S. Modular augmentation in revision total knee arthroplasty. Knee Surg Sports Traumatol Arthrosc. 2013;21(12): [34] Heesterbeek PJ, Wymenga AB, van Hellemondt GG. No difference in implant micromotion between hybrid fixation and fully cemented revision total knee arthroplasty: a randomized controlled trial with radiostereometric analysis of patients with mild-to-moderate bone loss. J Bone Joint Surg Am. 2016;98(16): [35] Kosse NM, van Hellemondt GG, Wymenga AB, et al. Comparable stability of cemented vs press-fit placed stems in revision total knee arthroplasty with mild to moderate bone loss: 6.5-year results from a randomized controlled trial with radiostereometric analysis. J Arthroplasty. 2017;32(1): [36] Gofton WT, Tsigaras H, Butler RA, et al. Revision total knee arthroplasty: fixation with modular stems. Clin Orthop Relat Res. 2002;(404): [37],,,. [J]., 2015,8(4): [38] Wang JW, Hsu CH, Huang CC, et al. Reconstruction using femoral head allograft in revision total knee replacement: an experience in Asian patients. Bone Joint J. 2013;95-B(5): [39] Clatworthy MG, Ballance J, Brick GW, et al. The use of structural allograft for uncontained defects in revision total knee arthroplasty. A minimum five-year review. J Bone Joint Surg Am. 2001;83-A(3): [40] Backstein D, Safir O, Gross A. Management of bone loss: structural grafts in revision total knee arthroplasty. Clin Orthop Relat Res. 2006;446: [41] Black J. Biological performance of tantalum. Clin Mater. 1994; 16(3): [42] Girerd D, Parratte S, Lunebourg A, et al. Total knee arthroplasty revision with trabecular tantalum cones: Preliminary retrospective study of 51 patients from two centres with a minimal 2-year follow-up. Orthop Traumatol Surg Res. 2016;102(4): [43] Brown NM, Bell JA, Jung EK, et al. The use of trabecular metal cones in complex primary and revision total knee arthroplasty. J Arthroplasty. 2015;30(9 Suppl): [44] Fedorka CJ, Chen AF, Pagnotto MR, et al. Revision total knee arthroplasty with porous-coated metaphyseal sleeves provides radiographic ingrowth and stable fixation. Knee Surg Sports Traumatol Arthrosc [45] Kamath AF, Lewallen DG, Hanssen AD. Porous tantalum metaphyseal cones for severe tibial bone loss in revision knee arthroplasty: a five to nine-year follow-up. J Bone Joint Surg Am. 2015;97(3): [46] van Hamersveld KT, Marang-van de Mheen PJ, Tsonaka R, et al. Fixation and clinical outcome of uncemented peri-apatite-coated versus cemented total knee arthroplasty : five-year follow-up of a randomised controlled trial using radiostereometric analysis (RSA).Bone Joint J. 2017;99-B(11): [47] Nelson CL, Vanushkina M, Irgit K, et al. Stemmed femoral implants show lower failure rates in revision total knee arthroplasty. Knee. 2015;22(5): [48] Lachiewicz PF, Soileau ES. A 30-mm cemented stem extension provides adequate fixation of the tibial component in revision knee arthroplasty. Clin Orthop Relat Res. 2015;473(1): [49] Nadorf J, Kinkel S, Gantz S, et al. Tibial revision knee arthroplasty with metaphyseal sleeves: The effect of stems on implant fixation and bone flexibility. PLoS One. 2017;12(5):e [50] Berend ME, Ritter MA, Keating EM, et al. Use of screws and cement in primary TKA with up to 20 years follow-up. J Arthroplasty. 2014;29(6): [51] Beckmann NA, Mueller S, Gondan M, et al. Treatment of severe bone defects during revision total knee arthroplasty with structural allografts and porous metal cones-a systematic review. J Arthroplasty. 2015;30(2): [52] Garcia RM, Kraay MJ, Conroy-Smith PA, et al. Management of the deficient patella in revision total knee arthroplasty. Clin Orthop Relat Res. 2008;466(11): [53] Masri BA, Meek RM, Greidanus NV, et al. Effect of retaining a patellar prosthesis on pain, functional, and satisfaction outcomes after revision total knee arthroplasty. J Arthroplasty. 2006;21(8): [54] Ries MD, Cabalo A, Bozic KJ, et al. Porous tantalum patellar augmentation: the importance of residual bone stock. Clin Orthop Relat Res. 2006;452: [55] Busfield BT, Ries MD. Whole patellar allograft for total knee arthroplasty after previous patellectomy. Clin Orthop Relat Res. 2006;450: [56] Rorabeck CH, Mehin R, Barrack RL. Patellar options in revision total knee arthroplasty. Clin Orthop Relat Res. 2003;(416): [57] Maheshwer CB, Mitchell E, Kraay M, et al. Revision of the patella with deficient bone using a biconvex component. Clin Orthop Relat Res. 2005;440: [58] Seo JG, Moon YW, Lim SJ, et al. Augmentation with transcortical wiring of an onlay-type prosthesis for a deficient patella during revision total knee arthroplasty. Clin Orthop Surg. 2012;4(2): [59] Gililland JM, Swann P, Pelt CE, et al. What Is the role for patelloplasty with Gullwing osteotomy in revision TKA? Clin Orthop Relat Res. 2016;474(1): [60] Nasser S, Poggie RA. Revision and salvage patellar arthroplasty using a porous tantalum implant. J Arthroplasty. 2004;19(5): [61] Qiu YY, Yan CH, Chiu KY, et al. Review article: bone defect classifications in revision total knee arthroplasty. J Orthop Surg (Hong Kong). 2011;19(2): [62] Luo W, Huang L, Liu H, et al. Customized knee prosthesis in treatment of giant cell tumors of the proximal tibia: application of 3-dimensional printing technology in surgical design. Med Sci Monit. 2017;23: ISSN CN /R CODEN: ZLKHAH

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