Pedicle screw placement combined with filler for lumbar vertebra fractures 19(22): doi: /j.issn

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1 Chinese Journal of Tissue Engineering Research May 28, 2015 Vol.19, No ( ) (XYDCX ) / Cobb :R318 :B : (2015) [J] (22): doi: /j.issn Pedicle screw placement combined with filler for lumbar vertebra fractures Zhou Gang 1, Gan Zi-ming 2, Huang Wei-min 1, Wang Cheng-wei 1 ( 1 Department of Spine Surgery, Sixth Affiliated Hospital, Xinjiang Medical University, Urumqi , Xinjiang Uygur Autonomous Region, China; 2 Basic Medical College, Xinjiang Medical University, Urumqi , Xinjiang Uygur Autonomous Region, China) Abstract BACKGROUND: Conventional cross-segment pedicle screw fixation will cause some complications such as kyphosis and loss of corrective angle. Fixation of pedicle screw placement of the injured vertebral body improves the disadvantages of conventional posterior screw placement, and obtains ideal outcomes. OBJECTIVE: To investigate the clinical application value of pedicle screw placement combined with filler for lumbar vertebra fracture. METHODS: Clinical data of patients with pedicle screw placement combined with filler for lumbar vertebra fracture were retrospectively analyzed. They were repaired with pedicle screw placement combined with bone graft as well as pedicle screw placement combined with bone cement. The ratio of anterior border to posterior border of the injured vertebral body after surgery and changes in Cobb angle were observed. Patients were followed up and results were compared. RESULTS AND CONCLUSION: Pedicle screw placement combined with filler has many advantages, and obtained good outcomes in the treatment of lumbar vertebral fracture. However, the extensive application has some problems and disputes. Clinical physicians should pay more attention on choice of surgical indications, prevention and treatment of perioperative and long-term complications and postoperative treatment of osteoporosis. The pedicle screw fixation combined with calcium phosphate bone cement has a broad prospect, can maintain the effect of spine reduction, and is worth to spread in the clinical treatment of lumbar fractures. Zhou Gang, Studying for master s degree, Attending physician, Department of Spine Surgery, Sixth Affiliated Hospital, Xinjiang Medical University, Urumqi , Xinjiang Uygur Autonomous Region, China Corresponding author: Gan Zi-ming, Professor, Master s supervisor, Basic Medical College, Xinjiang Medical University, Urumqi , Xinjiang Uygur Autonomous Region, China Accepted: P.O. Box 10002, Shenyang

2 . Subject headings: Pedicle Screw; Fractures, Bone; Calcium Phosphates Funding: Research Innovation Fund Project of Xinjiang Medical University, No. XYDCX Zhou G, Gan ZM, Huang WM, Wang CW. Pedicle screw placement combined with filler for lumbar vertebra fractures. Zhongguo Zuzhi Gongcheng Yanjiu. 2015;19(22): Introduction [1] [2] / β-tcp [3-7] [5] [8-12] 1Data and methods d 14 d4 d Certibein 1 A1 2 A2 10 A3 5 B1 4 B Frankel 4 B 2 C 6 D 22 [13] SPSS 13.0 Cobb 2 Results Cobb (P < 0.01) 1 1 Cobb (x _ ±s) Cobb ( ) 0.31± ± ± ± ± ± Cobb (P > 0.05) 12 ISSN CN /R CODEN: ZLKHAH 3591

3 . FrankelB 2 C 3 D 3 E [14] [15] ( ) [16] ( n=34) ( n=38) Cobb (P > 0.05) 1 Cobb (P < 0.05) ; (P < 0.05) Cobb 2 3 [17] 2 [14] [15] Cobb (x _ ±s ) [14] 21.8± ± ±1.2 [15] 33.6± ± ±2.5 3 [16] Cobb (x _ ±s ) ± ± ± ± ± ± Discussion [23] [24] Cobb 3592 P.O. Box 10002, Shenyang

4 . 4 ( ) [18] [19] [20] > 12 [21] [22] (n= 42 A ) 58 80(n=36 B ) A B [18] [19] [20] [21] [22] Cobb (P < 0.05) Frankel (P < 0.05) Cobb, (P < 0.05);(P > 0.05) 25,,,, 1 1,,, Cobb VAS A B (P > 0.05) Cobb VAS B A (P < 0.05) (P < 0.05) X CT2 A B Cobb VAS (P < 0.05) 1 A B (P < 0.05) 1 3 A B (P > 0.05) Cobb 50% % 60% [25] [26] Cobb ; ISSN CN /R CODEN: ZLKHAH 3593

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